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All Journal BALI MEDICAL JOURNAL (BMJ) INDONESIAN JOURNAL OF LEGAL AND FORENSIC SCIENCES Buletin Udayana Mengabdi E-Jurnal Medika Udayana Jurnal Veteriner The Indonesian Biomedical Journal ISM (Intisari Sains Medis) : Jurnal Kedokteran Neurologico Spinale Medico Chirurgico Bali Anatomy Journal Essential: Essence of Scientific Medical Journal Makara Journal of Science Hang Tuah Medical Journal Journal of Global Pharma Technology Jurnal Sains dan Kesehatan
I Gusti Kamasan Arijana
Departemen Histologi Fakultas Kedokteran Universitas Udayana
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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DISTRIBUSI GOLONGAN DARAH ABO-RH SISWA SDN 3 KETEWEL SUKAWATI GIANYAR N.M. Linawati; I.G.K.N. Arijana; I.N. Wande; I.W. Sugiritama; I.G.N.S. Wiryawan; I.G.A.D. Ratnayanti; I.A.I. Wahyuniari; D.A.A.S. Laksmi
Buletin Udayana Mengabdi Vol 21 No 4 (2022): Buletin Udayana Mengabdi
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/BUM.2022.v21.i04.p02

Abstract

Blood group is one of the identification parameters of a person's identity. Blood group is important to know in relation to medical and non-medical problems. However, there are still many blood group data that are not known to students in Ketewel village. This activity aims to determine the ABO-Rhesus blood group in children at SDN 3 Ketewel. The activity was carried out after coordinating with the Village Head, the headmaster of SDN 3 and also Mantra Medika Clinical Laboratory in Ketewel. Implementation of activities in August 2021 by complying with health protocols during the pandemic of Covid-19. The results of the activity were obtained as many as 65 students consisting of 35 male and 30 female which was 100% positive Rhesus. The distribution of ABO blood typing in male students was 14% A, 25% B, 62% O and 3% AB. Meanwhile, distribution of ABO blood type in female students is 13% A, 33% B and 47% O. From the activity, it can be concluded that the distribution of ABO-Rhesus blood group in SDN 3 Ketewel students is mostly O, the least blood group is AB which were all students Rhesus positive. Keywords: Identification, ABO-Rhesus blood group, SDN 3 Ketewel
POTENSI GASTROPROTEKTIF EKSTRAK BUNGA CENGKIH (Syzygium aromaticum): ANTIULKUS LAMBUNG, ANTIOKSIDAN, ANTIINFLAMASI, DAN ANTIMIKROBA Juven Luvianto; Ni Made Linawati; I Gusti Kamasan Nyoman Arijana; I Wayan Sugiritama
Essence of Scientific Medical Journal Vol 21 No 2 (2024): Volume 21 No. 2 (Juli - Desember 2023) Essential: Essence of Scientific Medical
Publisher : Kelompok Ilmiah Hippocrates Fakultas Kedokteran Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/essential.v21i2.109987

Abstract

Pendahuluan: Cengkih (Syzygium aromaticum) merupakan salah satu tanaman asli yang berasal dari Indonesia. Kandungan utama bunga cengkih adalah eugenol, ?-kariofilen, dan eugenol asetat. Gangguan pada sistem pencernaan atau gastrointestinal merupakan gejala ataupun penyakit yang menyebabkan ketidaknyamanan pada penderitanya, misalnya dispepsia, gastritis, maag, infeksi, konstipasi, perdarahan, ulkus lambung, dan penyakit degeneratif kronis yang dapat disebabkan oleh obat-obatan, minuman beralkolhol, merokok, makanan asam atau lemak tinggi, dan malnutrisi. Pembahasan: Aktivitas antiuklus lambung ekstrak bunga cengkih melalui peningkatan faktor protektif lambung seperti sintesis mukus lambung, bikarbonat, regulasi aliran darah mukosa lambung, serta menghibisi asam lambung. Ekstrak bunga cengkih juga berperan sebagai antioksidan dan antiinflamasi dengan mengurangi sitokin proinflamasi, misalnya IL-1?, IL-6, TNF-?, nitrogen oksida, NF-?B dan meningkatkan antioksidan seluler seperti P450 reduktase, superoksida dismutase, katalase, glutathion peroksida, gluthation, dan thiol non-protein. Aktivitas antimikroba ekstrak bunga cengkih meliputi antibakteri, antivirus, antifungi, dan antiprotozoa. Simpulan: Ekstrak bunga cengkih memiliki berbagai aktivitas biologis, seperti antiulkus lambung, antibakteri, antifungi, antiinflamasi, dan antioksidan. Introduction: Clove (Syzygium aromaticum) is one of Indonesia’s native plant. The main components of clove bud are eugenol, ?-caryophyllene, dan eugenol acetate. Gastrointestinal symptoms or disease can lead to patient feeling uncomfortable. For examples dyspepsia, gastritis, infection, constipation, bleeding, gastric ulcer, and chronic degenerative disease that may be caused by drugs, alcohol, smoking, acidic or fatty foods, and malnutrition. Discussion: Clove bud extract has a lot of biological activities such as, antiulcer, antibacterial, antifungal, antiinflammation, and antioxidant. The methods used for this literature review are from 41 journals and electronic databases search. The antiulcer component of clove bud extract works by increasing the gastric protective factor, such as synthetizing gastric mucous, bicarbonate, regulating gastric mucosal blood flow, and inhibiting gastric acid. Clove bud extract also plays a role as antioxidant and antiinflammation by reducing cytokines proinflammation like IL-1?, IL-6, TNF-?, nitrite oxide, NF-?B and enhancing cellular antioxidant, for example P450 reductase, superoxide dismutase, catalase, glutathione peroxidase, glutathione, thiol non-protein. The microbial activity of clove bud extract includes antibacterial, antiviral, antifungal, and antiprotozoal. Conclusion: Clove bud extract has several biological activity, such as antiulcer, antimicrobial, antibacterial, antifungal, antiinflammation, and antioxidant.
Efek Blueberry (Vaccinium sp.) Terhadap Kelembapan Kulit yang Terpapar Sinar Ultraviolet Akut ADNYANA PUTRA, I GEDE AGUS DIVA; IDA AYU IKA WAHYUNIARI; NI MADE LINAWATI; I GUSTI KAMASAN NYOMAN ARIJANA
Hang Tuah Medical Journal Vol 21 No 1 (2023): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v21i1.337

Abstract

Introduction: Maintained skin moisture is an indication of healthy skin. Acute UV exposure can cause sunburn, which is characterized by a loss of moisture in the skin. Polyphenol compounds are one practical approach to protecting the skin from sunburn so that skin moisture is maintained. Blueberries are one of the natural ingredients consists of anthocyanin compounds, which are polyphenols from the flavonoid group. Aims: To determine the effect of blueberries on skin moisture exposed to acute ultraviolet rays. Methods: Literature study using references in the form of research articles and literature reviews from national and international journals and related books published in the last 10 years. In writing this literature review, 42 references were used which were accessed through Google Scholar, NCBI, Crossref, and Pubmed. Results: Blueberries anthocyanins can maintain skin moisture from increased transepidermal water loss (TEWL) due to acute UV ray exposure by reducing the formation of UV stimulated reactive oxygen species (ROS) and lipid peroxidation in keratinocyte cells to maintain the elastic modulus and mechanical properties of keratinocytes as well as can prevent sunburn by reducing the skin's modulation of UV exposure. However, the absorption of anthocyanin compounds in the intestine is so low that taking blueberries orally alone is not enough to achieve good biodistribution. Conclusion: Blueberries affect retaining moisture in skin exposed to acute UV rays, so they have the potential to be used as skincare ingredients. However, further research needs to be done, especially to determine the side effects that can be caused and the required extract concentration.
Potensi Senyawa Fitokimia pada Tumbuhan dalam Menurunkan Kadar Glukosa Darah pada Diabetes Melitus: Potential of Phytochemical Compounds in Plants in Lowering Blood Glucose Levels in Diabetes Raymond Elbert Budianto; Ni Made Linawati; I Gusti Kamasan Nyoman Arijana; Ida Ayu Ika Wahyuniari; I Gusti Nyoman Sri Wiryawan
Jurnal Sains dan Kesehatan Vol. 4 No. 5 (2022): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v4i5.1259

Abstract

Diabetes melitus adalah gangguan metabolik kronis yang ditandai dengan hiperglikemia atau tingginya glukosa dalam darah karena gangguan dalam sekresi maupun respons terhadap hormon insulin. Menurut data dari International Diabetes Federation, prevalensi diabetes melitus di seluruh dunia sudah sangat tinggi, yaitu 537 juta pada tahun 2021. Akan tetapi, sudah ada berbagai obat alternatif alami yang dapat digunakan untuk menangani penyakit tersebut. Dalam beberapa penelitian, banyak tanaman yang sudah teruji khasiatnya sebagai obat antidiabetes alami karena kandungan fitokimianya. Studi literature review ini dilakukan dengan pencarian data melalui Google Scholar dan Science Direct dalam kurun  waktu 10 tahun terakhir (2013-2022). Dari 29 artikel yang sesuai diperoleh hasil bahwa beberapa kandungan fitokimia pada tumbuhan seperti alkaloid dengan kemampuannya memperbaiki sel beta pankreas, flavonoid sebagai astringen, saponin dengan kemampuannya menstimulasi sekresi insulin dari sel beta pankreas, dan tanin sebagai antioksidan alami berpotensi menurunkan glukosa darah pada diabetes melitus tipe 1 dan 2.
Co-Authors ADNYANA PUTRA, I GEDE AGUS DIVA Agus Dody Pranata Suadi Putra Anak Agung Ngurah Subawa Apolonia Berenika Badu Ayu Gita Bhagawanti Ayu Saka Laksmita W D.A.A.S. Laksmi Desak Putu Citra Udiyani Desak Putu Risky Vidika Apriyanthi Dewa Ayu Agus Sri Laksmi Dinesh Tanabbal ELVINA VERONICA Eugenia Meidy Fedik Abdul Ratam Gayathiri Mohana Krishnan Gede Wirata Hamsu Kadriyan Henky Henky I Dewa Ayu Eka Widiari Putri I Dewa Ayu Inten Primayanti I Dewa Made Agus Paramarta Putra I Gde Raka Widiana I Gusti Ayu Dewi Ratnayanthi I Gusti Ayu Dewi Ratnayanti I Gusti Kamasan I Gusti Ngurah Mayun I Gusti Nyoman Sri Wiryawan I Kadek Swastika I Ketut Tunas I Made Adi Satria Darma I Made Agus Endra Permana I Made Jawi I Made Sudarmaja I Nyoman Hariyasa Sanjaya I Nyoman Wande I Nyoman Wiryawan I Putu Dema Prasetya I Wayan Gede Artawan Eka Putra I Wayan Putu Sutirta Yasa I Wayan Sugiritama I Wayan Sugiritama I. G. A. D. Ratnayanthi I.G.N.S. Wiryawan I.N. Wande I.W. Sugiritama Ida Ayu Dewi Wiryantini Ida Ayu Ika Wahyuniari Intan Syahirah Bt Abdul Rauap JOHAN AXEL PARIURY Joshua Ezra Ronaldo Bayak JUAN PAUL CHRISTIAN HERMAN Juven Luvianto Komang Jegek Triangga Apsari Made Satria Yudha Dewangga Mahen Isaac Pannir Chelvam N. M. Linawati N.M. Linawati Ni Ketut Susilawati Ni Luh Ariwati Ni Luh Putu Eka Diarthini Ni Made Linawati Ni Made Mertaniasih Ni Made Yuli Lestari Ni Nyoman Mas Utari Rena Ni Nyoman Sri Budayanti Ni Putu Candra Paramita Ni Putu Sriwidyani Ni Putu Widayanti Ni Wayan Devi Yulianti Nyoman Intan Cahaya Pertiwi Nyoman Pratiwi Hapsari Dewi P.P.A.P. Dewi Putu Ayu Asri Damayanti Raymond Elbert Budianto Romdhoni, Achmad Chusnu Ruthirar Kalaichelvam Sri Maliawan Tarvin Jit Singh Gill TIFFANY REBECCA Tjokorda Gde Agung Suwardewa Wayan Aryadana Wayan Aryadana Wayan Suardana Yogarani V.C Rajappan