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All Journal Medula Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Kesehatan JK Unila (Jurnal Kedokteran Universitas Lampung) Nusantara Hasana Journal Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine
Oktadoni Saputra
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Journal : medula

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Sarkoma Ewing: Diagnosis dan Tatalaksana Hisbul Waton; Helmi Ismunandar; Oktadoni Saputra; Ratna Dewi Puspita Sari
Medula Vol 13 No 2 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i2.657

Abstract

Ewing's sarcoma (ES) is the second most common bone malignancy. It is accompanied by osteosarcoma. Ewing's sarcoma is most common in people between the ages of 10 and 20, or becomes more common in their 20s, and most cases affect males. The exact cause of Ewing's sarcoma is unknown, but it is currently associated with a translocation of chromosomes 11 and 12 which results in fusion of the EWS and FL-1 genes in 90% of cases. Ewing's sarcoma is often diagnosed with an extensive lesion and metastases, so the patient's prognosis is poor. Complaints that are often found in patients with Ewing's sarcoma are pain, fever, mass and fracture pathology. In addition, laboratory tests found an increase in blood sedimentation levels (ESR), anemia followed by an increase in white blood cells, lactate dehydrogenase (LDH). Radiographs show ill-defined, punctate, penetrating, or moth-eaten lesions, onion-like periosteal reaction, and abundant soft tissue around the diaphysis or metaphysis. Treatment of Ewing's sarcoma is a multimodal approach that combines chemotherapy, physical therapy, and radiation therapy. This combination has been shown to increase the 5-year survival rate of patients with Ewing's sarcoma to over 50%.
Orchitis Sebagai Komplikasi Infeksi Mumps (Gondongan): A Case Series Rizqiani Astrid Nasution; Oktadoni Saputra
Medula Vol 16 No 2 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i2.1896

Abstract

Mumps is a viral infectious disease that is generally self-limiting but may lead to serious complications, including orchitis, which can adversely affect future fertility, particularly in adolescent males. This case series aims to describe the clinical manifestations, diagnostic approach, and management of mumps-associated orchitis in a prepubertal child and an adolescent. Two male patients aged 11 and 15 years who were treated at Dr. H. Abdul Moeloek Hospital in 2024 were diagnosed with mumps orchitis. Both patients initially presented with parotid gland swelling followed by fever, scrotal swelling, and testicular pain several days later. Diagnosis was established through history taking, physical examination, laboratory investigations, and scrotal ultrasonography in one patient. Ultrasonographic findings demonstrated epididymo-orchitis characterized by enlargement of the testis and epididymis with increased vascularity. Both patients received supportive management, including hydration and analgesics, with additional therapies administered according to clinical indications. Clinical improvement was observed in both patients during hospitalization. This report highlights that orchitis may occur as a complication of mumps in both prepubertal and adolescent males, including those with a complete immunization history. Early recognition of orchitis symptoms in patients with mumps is essential to ensure timely diagnosis and appropriate management, thereby reducing the risk of long-term reproductive complications.
Demam Tifoid disertai Ankilostomiasis pada Anak Usia 5 Tahun: Sebuah Laporan Kasus Muhammad Morsa Habibie; Oktadoni Saputra
Medula Vol 17 No 1 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v17i1.2036

Abstract

Typhoid fever remains one of the most common infectious diseases affecting children in developing countries, particularly in areas with poor sanitation and hygiene. Meanwhile, hookworm infection continues to be a significant public health problem because it may cause chronic blood loss, iron deficiency anemia, malnutrition, and impaired growth in children. The coexistence of these two infections may aggravate clinical manifestations and requires a comprehensive diagnostic and therapeutic approach. This case report aims to describe the clinical presentation, diagnostic evaluation, and management of typhoid fever accompanied by hookworm infection in a child. A 5-year-11-month-old girl was admitted to the Emergency Department of dr. H. Abdul Moeloek Regional Hospital with a two-week history of fever accompanied by abdominal pain, vomiting, and diarrhea. Physical examination revealed fever, pale conjunctiva, and abdominal distension. Laboratory investigations demonstrated microcytic hypochromic anemia, leukocytosis, thrombocytosis, and hypoalbuminemia. Serological testing for anti-Salmonella IgM (TUBEX) yielded a positive result with a score of 6, while stool examination identified Ancylostoma duodenale eggs. The patient was diagnosed with typhoid fever and hookworm infection and was treated with intravenous antibiotics, an anthelmintic agent, supportive therapy, adequate fluid and nutritional management, and education regarding personal hygiene and sanitation. During hospitalization, the patient's clinical condition gradually improved, as evidenced by the resolution of fever, abdominal pain, vomiting, and diarrhea, along with improved tolerance to oral intake, and she was discharged in good condition. This case highlights the importance of considering coinfection in children presenting with prolonged fever, anemia, and poor sanitation-related risk factors. An integrated approach involving accurate diagnosis, appropriate antimicrobial and anthelmintic therapy, nutritional support, and preventive education is essential to improve clinical outcomes and reduce the risk of complications and reinfection.
Faktor Kecemasan Terhadap Ujian pada Mahasiswa Azzahra Fadhilla Amelia; Oktafany Oktafany; Shinta Nareswari; Oktadoni Saputra
Medula Vol 16 No 2 (2026): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v16i2.1798

Abstract

Test anxiety is a common psychological condition experienced by university students and can negatively affect academic performance and psychological well-being. This study aimed to examine the causes, manifestations, and impacts of test anxiety among students through a literature review approach. Relevant literature was obtained from Google Scholar and national and international scientific databases using the keywords “test anxiety,” “exam anxiety,” “students,” and “academic performance.” A total of 23 articles published between 2010 and 2025 met the inclusion criteria and were analyzed narratively. The findings revealed that test anxiety is influenced by various factors, including academic demands, social pressures, individual characteristics, and learning environment conditions. One of the reviewed studies by Bhuwana (2025) reported that 98.5% of students (197 of 200 respondents) experienced anxiety during the Objective Structured Clinical Examination (OSCE), with the primary causes being limited examination time (21%), the large amount of material to be studied (20.5%), and difficulties maintaining concentration or experiencing forgetfulness during examinations (19.5%). Manifestations of test anxiety include physical, cognitive, and behavioral symptoms such as increased heart rate, excessive worry, negative thoughts, impaired concentration, and procrastination. These symptoms may contribute to lower academic achievement, reduced learning motivation, increased stress levels, and emotional exhaustion. Therefore, effective stress management strategies and institutional support are essential to help students cope with examination-related stress, improve academic performance, and maintain psychological well-being through supportive learning environments and accessible counseling services.
Co-Authors Ani Yuli Yanti Puspitasari Ayu Aprilia Azzahra Fadhilla Amelia Bayu Anggileo Pramesona Chalida, Aprilly Adlina Dwita Oktaria Erlita Kusuma Wardani Evi Kurniawaty Galih Prasetio Ekin Basuki Utomo Hanifah Rahmania Helmi Ismunandar Hisbul Waton Idzni Mardhiyah Indri Windarti Khairun Nisa Lariza Serafina Tobroni Liana Sidharti Made Afryan Merry Indah Sari Muhammad Mahardika Malik Muhammad Morsa Habibie Muhammad Yazid Daradjat Nabilla Nabilla Natasyah Hana Zafirah Novita Carolia Nurul Utami Oktafany Oktafany Oktafany, Oktafany Ratna Dewi Puspita Sari Reni Zuraida Rika Lisiswanti Rika Lisiswati Rizqiani Astrid Nasution Rodiani Rodiani Shinta Nareswari Siti masruroh TA Larasati Winda Trijayanthi Utama, Winda Trijayanthi Zamahsjari Sahli