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All Journal Biomedika Jurnal Kesehatan Herb-Medicine Journal Bioscientia Medicina : Journal of Biomedicine and Translational Research Prosiding University Research Colloquium International Journal of Health Science and Technology JHeS (Journal of Health Studies) Magna Neurologica
Sulistyani Sulistyani
Universitas Muhammadiyah Surakarta
Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Education Engineering Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health

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Relationship of acid–base imbalance with hemorrhage volume and mortality in intracerebral stroke hemorrhage Gavin Mukti; Iwan Setiawan; Metana Puspitasari; Sulistyani Sulistyani
JHeS (Journal of Health Studies) Vol. 10 No. 1 (2026): Maret
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/jhes.4008

Abstract

This study aimed to evaluate the relationship between acid-base balance disturbances and intracerebral hemorrhage volume with mortality rates in hemorrhagic stroke cases. The research used an observational analytic design with a cross-sectional approach and was conducted at Dr. Soeratno Gemolong General Hospital, Sragen, from September to November 2024. The study population consisted of medical records of patients diagnosed with hemorrhagic stroke at the hospital between August 2021 and August 2024 who met the inclusion criteria. A total of 50 samples were selected using a purposive sampling technique. Data analysis included univariate analysis, bivariate analysis using the Chi-Square test, and multivariate analysis using logistic regression. The results showed a significant relationship between acid–base balance disturbances and intracerebral hemorrhage volume with mortality in hemorrhagic stroke cases (p=0.001). In addition, intracerebral hemorrhage volume was significantly associated with mortality (p=0.007). Multivariate analysis confirmed that both acid–base imbalance and hemorrhage volume significantly influence mortality outcomes. These findings indicate that acid–base imbalance and intracerebral hemorrhage volume greater than 30 ml are strong predictors of mortality in hemorrhagic stroke patients. Therefore, strict monitoring of arterial blood gases, neurological status, and hemodynamic stability is essential during the acute phase of care. Early detection of physiological deterioration and prompt intervention may help reduce the risk of adverse outcomes. Future research is recommended to use prospective multicenter designs with larger sample sizes to further clarify causal relationships and evaluate whether early correction of acid–base disturbances can improve mortality outcomes in hemorrhagic stroke patients.
Co-Authors ., Subandi Aditya Nur Rahman Anika Candrasari Anita Arum Wijayatri Annisa Qotrunnajah Arif Apriyanto Arif Setiawan Arum Setya Pertiwi Atika Fatwa Yukhabilla Azahra Khansa Muza Baarid Lukman Hamidi Budianto, Pepi Burhannudin Ichsan Dessy Wahyuni Diah Kurnia Mirawati Dodik Nursanto Dwi Kusumaningsih Endang Kusuma Dewi Erna Herawati Gavin Mukti Hanindya Riani Prabaningtyas hinta Riana Setiawati Iin Novita Nurhidayati Mahmuda Iwan Setiawan Iwan Setiawan Iwan Setiawan Izzati Paramadina Metana Puspitasari Nadya Dwi Puspitasari Nanda Arum Andyani Ninda Pradani Futana Nining Lestari Oktaberika Putri Indah Yasinta Retno Sintowati Rivan Danuaji Siti Soekiswati Siti Zulfatul Afifah Sri Wahyu Basuki Suroto Suroto Tri Agustina Yetty Hambarsari Yusuf Alam Ramadhan Yusuf Alam Romadhon