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All Journal Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga. Biology, Medicine, & Natural Product Chemistry Biomedika Jurnal Pengabdian Kepada Masyarakat (Indonesian Journal of Community Engagement) Herb-Medicine Journal Health Information : Jurnal Penelitian Medica Arteriana (Med-Art) Lontara: Journal of Health Science and Technology Proceeding ISETH (International Summit on Science, Technology, and Humanity) Prosiding University Research Colloquium Jurnal Pengabdian Masyarakat Medika JHeS (Journal of Health Studies) Ibnu Sina: Jurnal Kedokteran dan Kesehatan - Fakultas Kedokteran Universitas Islam Sumatera Utara Lontara Journal Of Health Science And Technology Biomedika
Devi Usdiana Rosyidah
Universitas Muhammadiyah Surakarta
Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Phenytoin Topical as Pain Neuropathic Therapy: A Scoping Review Sulistyani, S; Rosyidah, Devi Usdiana; Rahmawati, Nailena Widya; Nugrahaen, Sarwasri Fajra; Goprani, Lidya; Sulistiyo, Azka Hafiy; Prameswari, Elza; Hutami, Norma Putri; Azwar, Muhammad Thoriq; Amalia, Riza
Proceeding ISETH (International Summit on Science, Technology, and Humanity) 2024: Proceeding ISETH (International Summit on Science, Technology, and Humanity)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/iseth.5500

Abstract

Background: Neuropathic pain is a type of pain that can cause prolonged pain in patients. Oral treatment takes a long time and can cause side effects, which can further reduce patient compliance with therapy. Topical treatment is a more acceptable alternative because it has minimal systemic side effects. Phenytoin is an anticonvulsant drug that can be used as a therapy for neuropathic pain. The side effects of oral phenytoin are minimized by using topical preparations. Objective: To obtain information on the effectiveness of topical phenytoin in neuropathic pain. Long-term goal, conduct clinical trials in patients and make topical phenytoin preparations in collaboration with one of the PBF (Large Pharmaceutical Companies) in Indonesia. Methods: Three electronic databases were searched on January 13, 2022: Google Scholar. PubMed and ScienceDirect. All relevant literature was included after screening according to the PRISMA statement. Data obtained were synthesized based on PICO (population, interventions, comparisons, and outcomes). Results: This paper examines case reports, case series, and pre-existing research articles in which topical phenytoin significantly reduces neuropathic pain. Conclusion: Topical phenytoin may be an alternative in the selection of neuropathic pain therapy due to its minimal side effects compared to oral therapy. However, further studies need to be conducted to compare with other topical anticonvulsants.
Sleep quality and low-density lipoprotein cholesterol levels with the risk of ischemic stroke Sari, Nur Amalia; Sulistyani, Sulistyani; Rosyidah, Devi Usdiana; Romadhon, Yusuf Alam
JHeS (Journal of Health Studies) Vol. 9 No. 1 (2025): Maret
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/jhes.3558

Abstract

Stroke is a multi-causal disease, and many factors can lead to stroke. There are also some unseen behavioral factors, such as poor diet. In recent years, poor sleep quality has been considered a potential trigger of stroke. If these factors are not well controlled, it can have an impact on the incidence of ischemic stroke. The aim of this research is to assess the correlation between sleep quality and low-density lipoprotein cholesterol levels with the incidence of ischemic stroke. This study used an analytic observational design with a cross-sectional approach using the PSQI (Pittsburgh Sleep Quality Index) questionnaire and secondary data. A total of 60 respondents were selected with a purposive sampling technique and met the inclusion and exclusion criteria. This research was conducted at Fatmawati Soekarno Hospital, Surakarta City. Statistical analysis showed that the Chi-Square test produced a significance value, with a p value of 0.007 for the correlation of sleep quality with the incidence of ischemic stroke, and a p value of 0.688 for the correlation of low-density lipoprotein cholesterol levels with the incidence of ischemic stroke. It can be concluded that there is a correlation between sleep quality and the incidence of ischemic stroke, but there is no relationship between low-density lipoprotein cholesterol levels and the incidence of ischemic stroke.
INVESTIGATION OF THE ANTIBACTERIAL EFFICACY OF DERSONO WATER APPLE LEAVES (SYZYGIUM MALACCENSE) AS A SUBSTITUTE THERAPY FOR STREPTOCOCCUS PYOGENES INFECTIONS Rosyidah, Devi Usdiana; Mahmudah, Nur; Fithriyah, Sa’idatul; Sintowati, Retno
Biomedika Vol 17, No 2 (2025): Biomedika August 2025
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v17i2.12007

Abstract

Streptococcus pyogenes caused different illnesses, including pharyngitis and dermatological infections. The Dersono water apple leavesSyzygium malaccense) are recognized for their bioactive ingredients, which may serve as antibacterial agents. This study purpose was to determine the antibacterial potential of ethanol extract and acetone fraction of Syzygium malaccense against Streptococcus pyogenes infection. This research was a laboratory xperiment, a post-test only with control group design. Assessing growth inhibition by measuring the diameter of halo around the well of blood agar plate. Statistical tests using the Sapiro-Wilk test, Lavene test, Kruskal Wallis est and Mann-Whitney test. The study's findings demonstrated that the ethanol extract 25% (11.80 mm) and 50% (16.51) concentrations and acetone fraction of Dersono water apple leaves, at 25% (11.25 mm) and 50% (12.08) concentrations, had strong inhibitory power. The concentrations of 6.25% (8.15 mm) and 12.50% (9.63 mm), the ethanol extract's inhibitory power was superior than the concentrations of 6.25% (4.42 mm) and 12.50% (3.38 mm) acetone fraction, had moderate range. Both the ethanol extract and the acetone fraction's phytochemical analyses identified alkaloids, tannins, and saponins. The conclusion was ethanol extract and acetate fraction of Dersono water apple leaves have antibacterial effects against Streptococcus pyogenes.
PELATIHAN USAHA KESEHATAN SEKOLAH (UKS) DAN PERTOLONGAN PERTAMA PADA KECELAKAAN (P3K) GURU SEKOLAH AMAL USAHA MUHAMMADIYAH Rosyidah, Devi Usdiana; Mahmudah, Nur; Sulistyani, Sulistyani; Agustina, Tri; Lestari, Nining; Nurwaini, Setyo
Jurnal Pengabdian Masyarakat Medika Vol 5. No. 2, September 2025
Publisher : Universitas Muhamamdiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/jpmmedika.v5i2.12204

Abstract

ABSTRAK Kemandirian siswa-siswi Taman Kanak-kanak (TK) dan Madrasah Ibtidaiyah (MI) masih rendah. Guru menjadi pembimbing dan pengganti orang tua saat kegiatan sekolah. Guru dituntut untuk memiliki kemampuan bidang akademik, dan non akademik berkaitan dengan kesehatan anak didik saat kegiatan di dalam dan diluar sekolah. Lingkungan sekolah sehat, ketersediaan perlengkapan kesehatan, personil guru yang kompeten dibidang Usaha Kesehatan Sekolah (UKS) dan Pertolongan Pertama Pada Kecelakaan (P3K) menjadi salah satu modal menciptakan lingkungan kondusif bagi anak didik. Guru penanggung jawab UKS sekolah Muhammadiyah tingkat TK dan MI di Kecamatan Gondangrejo belum pernah mendapatkan pelatihan khusus mengenai UKS dan P3K. Berdasarkan hal tersebut kami mengadakan pengabdian masyarakat melalui pelatihan Usaha Kesehatan Sekolah (UKS) dan Pertolongan Pertama Pada Kecelakaan (P3K) untuk Guru Sekolah Taman Kanak-Kanak dan Madrasah Ibtidaiyah Amal Usaha Muhammadiyah. Metode kegiatan berupa seminar, workshop, pembuatan buku panduan UKS, poster kesehatan, serta pembagian perlengkapan UKS dan P3K. Peserta pelatihan adalah perwakilan guru dari TK dan MI Muhammadiyah se-kecamatan Gondangrejo Kabupaten Karanganyar. Peningkatan kompetensi dapat diberikan dengan pemberian pengetahuan dan pelatihan. Nilai postes lebih tinggi dibanding nilai pretes. Menciptakan sekolah sehat merupakan tanggung jawab seluruh civitas sekolah, baik guru, siswa, karyawan sekolah, maupun orang tua siswa.   ABSTRACT The independence of kindergarten (TK) and Madrasah Ibtidaiyah (MI) students is still low. Teachers act as mentors and substitutes for parents are required to have academic and non-academic skills related to the health of students during activities. A healthy school environment, the availability of health equipment, and teaching staff who are competent in School Health Services (UKS) and First Aid (P3K) are some of the factors that contribute to creating a conducive environment for students. Teachers in charge of UKS at Muhammadiyah kindergarten and MI levels in Gondangrejo Subdistrict have never received special training on UKS and P3K. Based on this, we held a community service program through training on School Health Efforts and First Aid for Accidents for teachers. The methods used were seminars, workshops, the creation of UKS guidebooks and posters, and the distribution of UKS and P3K equipment. The training participants were teacher representatives from Muhammadiyah kindergartens and elementary schools in the Gondangrejo sub-district of Karanganyar Regency. Competency improvement can be achieved through the provision of knowledge and training. The post-test scores were higher than the pre-test scores. Creating a healthy school is the responsibility of the entire school community, including teachers, students, school employees, and parents.
Effect of PEG and CMC on Papaya (Carica papaya L.) Extract Against Aedes aegypti Larvae Bestari, Rochmadina Suci; Rif'aini, Fidhia Nur; Aisyah, Riandini; Dewi, Listiana Masyita; Rosyidah, Devi Usdiana; Sintowati, Retno; Karuniawati, Hidayah
Biology, Medicine, & Natural Product Chemistry Vol 14, No 2 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.142.961-968

Abstract

Dengue haemorrhagic fever (DHF) cases are still high in America and Asia region, including Indonesia. Eradication of DHF can be done by larvacide. Temephos 1%, chemical larvacide used in Indonesia for decades, can cause environment degradation and allergic reaction in human. Papaya stem extract as biolarvacide contains saponins, tannins, alkaloids, flavonoids, papain and essential oils which have larvicidal activity. It can be applicable in all over the world. This study was conducted to determine the better suspending agent between CMC or PEG of papaya stem extract to kill Aedes aegypti larvae. Objective: To determine the better suspending agent to kill Aedes aegypti larvae. Method: This study was true experimental study in laboratory, used post-test only controlled group design. This study used samples consist of Aedes aegypti instar III-IV larvae. There were seven experimental groups, consist of positive control group, negative control group for CMC, negative control group for PEG, extract concentration of 1.5% with CMC suspending agent, extract concentration of 1.5% with PEG suspending agent, extract concentration of 2% with CMC suspending agent, extract concentration of 2% with PEG suspending agent. Each group was repeated 4 times and counted every 6 hours (6th, 12th, 18th, 24th). Data analysis using the SPSS application ver 23. Probit test used to determine the effectiveness of the larvacide, LC50 and LT50 to determine the concentration and time to kill 50% of Aedes aegypti larvae. It used Kruskal Wallis Test to compare four dependent groups. It used Mann Whitney Test to compare the differences of each group. Result: The study showed that LC50 PEG was 0.033%, LC50 CMC was 0.321%, LT50 (PEG+1.5%) was 20.8 hours, LT50 (PEG+2%) was 30.7 hours, LT50 (CMC+1.5%) was 23.5 hours, LT50 (CMC+2%) was 40.7 hours. Based on the probit test, the LC50 and LT50 results showed that papaya stem methanol extract with PEG suspending agent was more effective than CMC suspending agent, it needed lower concentration and lower time to kill 50% of larvae. Kruskall Wallis Test result p<0.05, so there was significantly difference between groups. Post hoc Mann-Whitney Test result p<0.05 between C(-) PEG group with P1, P2, P3, P4 and between C(-) CMC group with P1, P2, P3, P4, so there was significantly difference between C(-) PEG with each group and C(-) CMC with each group. Conclusion: It can be concluded that papaya stem methanol extract with PEG suspending agent was more effective than CMC suspending agent to kill Aedes aegypti larvae.
Review Efektivitas Hipnoterapi Dalam Menurunkan Kualitas Dan Kuantitas Gejala Irritable Bowel Syndrome (Ibs) El Mubaraq, Syahrun; Herawati, Erna; Rosyidah, Devi Usdiana; Risanti, Erika Diana
Prosiding University Research Colloquium Proceeding of The 13th University Research Colloquium 2021: Mahasiswa (Student Paper)
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Irritable bowel syndrome merupakan salah satu penyakitpsikosomatik yang paling sering dijumpai. Irritable bowelsyndrome mengenai mengenai sistem saluran cerna bagianbawah. Mekanisme pasti sampai saat ini masih belum diketahuisecara pasti namun salah satu bukti yang kuat menyatakanadanya kaitan masalah signaling sistem saraf enterik dengan otak(brain-gut-axis) yang ada kaitannya dengan gangguan jiwaberupa depresi dan kecemasan yang meningkat 3 kali lipat selamaera pandemi COVID 19. Hipnoterapi bekerja pada sistem sarafpusat dan dapat memodifikasi fungsi dari brain-gut-axis yangsecara teori dapat menjadi terapi untuk perbaikan gejala IBS.Tujuan dari penelitian ini adalah menganalisis efektivitashipnoterapi dalam menurunkan gejala IBS. Metode penelitian iniberupa review literatur secara naratif dengan melakukanpencarian secara daring dengan menggunakan database yangmeliputi PubMed, Science Direct, dan Cochrane Library denganmenggunakan kata kunci “Hypnosis” dan “Irritable BowelSyndrome” baik dalam bentuk MeSH termnya maupun dalambentuk free termsnya. Hasil yang ditemukan adalah 5 artikel yangsesuai dengan tahun pencarian. Terdapat 4 artikel yangmembahas terkait penurunan gejala IBS dan 3 artikel yangmembahas terkait peraikan kualitas hidup penderita IBS. Hasilyang didapatkan adalah hipnosis secara efektif dapat menurunkangejala IBS. Hipnoterapi juga secara efektif dapat meningkatkankualitas hidup penderita IBS. Hasil post test dan follow up tetapmemberikan hasil yang konsisten. Tidak ada laporan efeksampaing terkait penggunaan hipnoterapi, namun efikasinyasangat bergantung pada kemampuan terapis dan tingkatsugestibilitas pasien.
Co-Authors Afif Iqbal Hibatullah Ahmad Rosid Nasrulloh Arifqi Alghozi, Muhammad Hilmi Amalia, Riza Anam, Zahra Hafizha Fitria Ananda Asriany Perdana Ananda Asriany Perdana, Ananda Asriany Anika Candrasari Anshar, Rizadin Azwar, Muhammad Thoriq Burhannudin Ichsan Burhanuddin Ichsan E. M. Sutrisna El Mubaraq, Syahrun Em Sutrisna Erika Diana Risanti Erna Herawati Erna Herawati, Erna Faatiha, Arsyal Wanda Fadhila, Zahra Hayuna Farid Santya Budi Febrian Dwi Cahyo Fithriyah, Sa’idatul Futana, Ninda Pradani Goprani, Lidya Graffico Eryza Oldiara Hibatullah, Afif Iqbal Hidayah Karuniawati Hutami, Norma Putri Iin Novita Nurhidayati Mahmuda Ilham Fahrudin Indra Nuroso Indwiani Astuti Indwiani Astuti Iwan Setiawan Jayanti Wulansari Jayanti Wulansari, Jayanti Kusumaningrum, Tanjung Anitasari Indah Lestari, Nining Listiana Masyita Dewi Listyana Masyita Dewi Maulana , Iqbal Nugrahaen, Sarwasri Fajra Nur Mahmudah Oktein Satriyani Prameswari, Elza Primayanti, Yustika Qasthari Rahmawati, Nailena Widya Ratih Pramuningtyas Retno Sintowati - Riandini Aisyah Rif'aini, Fidhia Nur Rizadin Anshar Rochmadina Suci Bestari Safari Wahyu Jatmiko Santosa, Talitha Ulima Santoso, Talitha Ulima Sari, Nur Amalia Satriyani, Oktein Setyo Nurwaini Sitarina Widyarini Sulistiyo, Azka Hafiy Sulistyani Sulistyani Sulistyani, S Supraba, Intan Pratiwi Susanto, Syarafina Ayu Putri Syah, Devan Adil Syahrun El Mubaraq Talitha Ulima Santoso Tanjung Anitasari Indah Kusumaningrum Tri Agustina Tri Agustina, Tri Utami, Indari Wibowo, Muhammad Irfan Sulystyo Yustika Qasthari Primayanti Yusuf Alam Romadhon Zelindrah, Virgil