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All Journal Archive of Community Health Media Kesehatan Masyarakat Indonesia e-Journal Pustaka Kesehatan Berkala Ilmiah Pertanian Jurnal Kesehatan Masyarakat (IKESMA) MPI (Media Pharmaceutica Indonesiana) UNEJ e-Proceeding Health Notions Multidiciplinary Journal Jurnal Kesehatan Jurnal Ners Jurnal Kesehatan Amanah
Isa Marufi
Bagian Kesehatan Lingkungan Dan Kesehatan Keselamatan Kerja Fakultas Kesehatan Masyarakat Universitas Jember
Agriculture, Biological Sciences & Forestry Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Library & Information Science Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health

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Analisis Risiko Kesehatan Lingkungan Sisa Klor (Cl2) pada ZAMP Perumda Air Minum Tugu Tirta Kota Malang Hanung Sinandi Arista Putra; Isa Ma'rufi; Ellyke Ellyke
Pustaka Kesehatan Vol 10 No 2 (2022): Volume 10 No.2, 2022
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v10i2.29406

Abstract

Zona Air Minum Prima (ZAMP) drinking water produced by the Perumda Air Minum Tugu Tirta Kota Malang can be consumed through taps directly from people's homes or ZAMP ready-to-drink water taps in public facilities. One of the processing processes is by adding chlorine gas to ZAMP water so that if the water consumed by the community is not processed further, there will be residual chlorine that enters the human body. The aim of this study is to analize the health risk due to residual chlorine that enters the human body. This descriptive study examined ZAMP water samples located in 9 public facilities in Sawojajar Malang. The residual chlorine was determined with laboratory test and analyzed with Enviromental Health Risk Assessment (EHRA). The result showed that the average residual chlorine content in ZAMP drinking water is 0.00611 mg/l, with a maximum value of 0.2 mg/L and a minimum of 0.001 mg/L. Risk characterization in the population shows that the risk of residual chlorine through ingestion is less than one (RQs < 1) both in adult and the children's category. There was no risk of exposure to residual chlorine contained in ZAMP within the next 30 years. Efforts to manage the risk of residual chlorine from exposure to residual chlorine in drinking water of ZAMP Perumda Water Drinking Tugu Tirta Malang City are not needed.
Effect of High Density Polyethylene on Inflammatory Responses in Wistar Rats (Rattus norvegicus) Talitha Maurilla Zulkarnain; Isa Ma’Rufi; Candra Bumi
Jurnal Ners Vol. 10 No. 1 (2026): JANUARI 2026
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v10i1.53107

Abstract

Microplastics were a newly emerging type of environmental pollutant composed of plastic particles with a diameter of less than 5 mm. The use of plastic food containers, plastic packaging, and plastic bottles could lead to direct contact and contamination of plastic into food. Microplastics were particles that could not be degraded by phagocytes, allowing inflammation to persist chronically and potentially cause organ dysfunction.The objective of this study was to analyze the effect of oral administration of various doses of HDPE microplastics on neutrophil levels in Wistar rats (Rattus norvegicus). The research method was an experimental study with a post-test only control group design, consisting of one control group and three treatment groups. Neutrophil levels in Wistar rats were measured using an automatic hematology analyzer. The results of neutrophil measurements were analyzed using the Kruskal–Wallis test followed by the Bonferroni post hoc test.The the research results indicate the highest neutrophil levels were observed in the treatment group receiving the highest dose of 0.4 mg/kg/day (X3). The Krus kal–Wallis test yielded a p-value of 0.000 < 0.05, indicating a significant effect among the treatment groups receiving various doses of orally administered HDPE microplastics on the neutrophil levels of Wistar rats.
Bibiliometrics Menggunakan Analisis R-Bibiloshiny Resistensi Insulin pada Obesitas Kelompok Dewasa Database Scopus (2019-2025) Krish Naufal Anugrah Robby; Rachmad Gusti Irwansyah; Leersia Yusi Ratnawati; Candra Bumi; Irma Prasetyowati; Isa Ma’rufi; Dedek Sutinbuk; Farida Wahyu Ningtyias; Anita Dewi Prahastuti Sujoso; Dewi Rokhmah; Ida Srisurani Wiji Astuti
Jurnal Kesehatan Amanah Vol. 8 No. 2 (2024): Jurnal Kesehatan Amanah
Publisher : Universitas Muhammadiyah Manado

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57214/jka.v8i2.678

Abstract

contributing to the global burden of type 2 diabetes, cardiovascular diseases, and other metabolic complications. This bibliometric study aims to analyze trends, thematic focuses, and collaborations in scientific publications related to insulin resistance in adult obesity, utilizing data from the Scopus database covering the period from 2019 to 2025. Bibliometric tools such as RStudio, Biblioshiny, and VoS Viewer were employed to extract and visualize findings from 8,037 publications. The results reveal that research activity peaked in 2021, followed by a decline in subsequent years. Dominant keywords, such as "insulin resistance," "obesity," and "metabolic syndrome," highlight the clinical and metabolic focus of current research. Biomolecular markers, such as "glycated hemoglobin" and the "triglyceride-glucose index," reflect a growing interest in more precise diagnostic tools. The United States, China, and Italy emerged as major contributors, with journals like Nutrients and Frontiers in Endocrinology leading in publications. Despite significant progress, there remains a considerable gap, particularly in exploring the role of epigenetics and the microbiota in insulin resistance. Additionally, cross-disciplinary collaboration and participation from institutions in developing countries remain limited. This study emphasizes the importance of global, interdisciplinary efforts to address these gaps and drive innovation in interventions, providing a foundation for future research aimed at reducing the impact of insulin resistance in adult obesity.
Co-Authors Abu Khoiri Aditya Sapta Wardana Ahmad Afifuddin Sholeh Akbar, Kurnia Ardiansyah Al Munawir Ana Islamiyah Syamila Ancah Caesarina Novi Marchianti Anita Dewi Moelyaningrum Anita Dewi Prahastuti Anita Dewi Prahastuti Sujoso Anita Dewi Prahastuti Sujoso Anita Dewi PS. Ari Rizki Racheshi Aristha Dwi Wirapraja Ariusta, Indriany Maya Candra Bumi Dedek Sutinbuk Devit Dewi Anggraini Dewi Prihatini Dewi Rokhmah Dewi Rokhmah Rokhmah Dhanny Indra Prasetya Dian Septivita Ekin Akhsa Febriandini Ellyke Endah Putri Erdi Istiaji Eri Witcahyo Erisa Yuniardiningsih Farida Wahyu Ningtyias, Farida Wahyu Fariha Mariroh Fihris Maulidiah Suhma Globila Nurika Hadi Prayitno Hanung Sinandi Arista Putra Heri Prasetyo Icha Rohmah Damayanti Agustin Ida Srisurani Wiji Astuti Ikmala, Riskita Indriany Maya Ariusta Irma Prasetyowati Khairul Anwar Krish Naufal Anugrah Robby Lailatul Rahmawati Leersia Yusi Ratnawati Luh Putu Ratna Sundari Mardiyanti Mardiyanti Meri Dwi Apriliyanti Meri Dwi Apriliyanti Mochammad Sholehhudin Nonik Aisyah Rohman Novita Firdaus Nurul Hidayat Pandan Wangi Pramudita, Merissa Prehatin Trirahayu Ningrum Rachmad Gusti Irwansyah Ragil Ismi Hartanti Rahayu Sri Pujiati Rayi Siti Nurbaya Reny Indrayani Riselvia Nurhayati Riskita Ikmala Ristya Widi E Y Ristya Widi Endah Yani Rosyta Dwi Untika Putri Septivita, Dian Siti Fatimatun Navisah Sri Hernawati Talitha Maurilla Zulkarnain Titit Pramiasih Weni Widiyasari Yessinta Trizna Amanda Zarah Puspitaningtyas