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All Journal Paduraksa : Jurnal Teknik Sipil Universitas Warmadewa Alchemy : Journal of Chemistry Jurnal Harpodon Borneo Biotropika Jurnal Pendidikan dan Pembelajaran Kimia (JPPK) Jurnal Pengabdian Kepada Masyarakat Universitas Bangka Belitung Agrokreatif Jurnal Ilmiah Pengabdian kepada Masyarakat Elkawnie EduChemia: Jurnal Kimia dan Pendidikan Pharmascience Chimica et Natura Acta Acta Pharmaciae Indonesia : Acta Pharm Indo Prosiding SNFA (Seminar Nasional Fisika dan Aplikasinya) Indonesian Journal of Pure and Applied Chemistry Chemistry Indonesian Journal of Chemical Research Martabe : Jurnal Pengabdian Kepada Masyarakat Jurnal GEOSAPTA Fullerene Journal of Chemistry ALKIMIA : Jurnal Ilmu Kimia dan Terapan Stannum : Jurnal Sains dan Terapan Kimia ASEAN Journal of Chemical Engineering Jurnal Abdi: Media Pengabdian Kepada Masyarakat EKOTONIA: Jurnal Penelitian Biologi, Botani, Zoologi dan Mikrobiologi Jurnal Sains dan Edukasi Sains Jurnal Pijar MIPA Asian Journal of Health and Applied Sciences Indonesian Journal of Community Empowerment Dharma Pengabdian Perguruan Tinggi (DEPATI) Jurnal Pengabdian Pada Masyarakat
Robby Gus Mahardika
Departement Of Chemistry, Faculty Of Engineering, Universitas Bangka Belitung Jl. Kampus Peradaban, Merawang, Bangka, 33172
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Synthesis of dihydropyrimidinone derivatives using kelubi fruit (Eleiodoxa conferta) as a catalyst and its antibacterial activity Sari, Ratih Puspita; Nurhadini, Nurhadini; Mahardika, Robby Gus
Asian Journal of Health and Applied Sciences Vol. 1 No. 1 (2022): Asian Journal of Health and Applied Sciences (AJHAS)
Publisher : Lighthouse Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (555.555 KB) | DOI: 10.53402/ajhas.v1i1.5

Abstract

Kelubi fruit is one of the many fruits that grow in Bangka Belitung which has a sour taste. Kelubi fruit contains ascorbic acid, malic acid and oxalic acid. The potency and sour taste of Kelubi fruit can be used as a catalyst in the synthesis of dihydropyrimidinone compounds and activity as antibacterial. Dihydropyrimidinone compounds were synthesized using synthesis with the basic ingredients of benzaldehyde, urea and ethyl acetoacetate using natural catalysts that are more environmentally friendly. The purpose of this study was to determine the optimum volume, time and temperature catalyst used by kelubi fruit to synthesize pyrimidine-derived compounds as antibacterial. The optimization results on the synthesis of dihydropyrimidinone compounds using kelubi fruit water as a catalyst (Eleiodoxa conferta) with a lot of 0.3 mL catalyst, temperature of 50ºC and reaction time of 4 hours with yield of 46.75%. Antibacterial activity of dihydropyrimidinone compounds against Stapylococcus aureus bacteria at a concentration of 10 ppm, 30 ppm including the category and a concentration of 75 ppm including the medium category. Antibacterial activity against Eschericia coli bacteria at concentrations of 30 ppm and 75 ppm was categorized as weak.
Peel-off mask formulation from bintangur (Calophyllum inophyllum L.) leaf ethanol extract and its antibacterial activity Liska, Liska; Amanah, Hairil; Novianti, Shindi; Mahardika, Robby Gus
Asian Journal of Health and Applied Sciences Vol. 1 No. 2 (2022): Asian Journal of Health and Applied Sciences (AJHAS)
Publisher : Lighthouse Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53402/ajhas.v1i2.29

Abstract

One of the most widely distributed plant species in Bangka Belitung is Bintangur (Calophyllum inophyllum L.) which is a genus of the Clusiaceae family. Bintagur leaf has the potential as a mask against acne-causing bacteria because it has high bioactivity such as antioxidants and antibacterials. Bitangur leaf extract masks were made by mixing the raw materials in the form of PVA 10 g; HPMC 1 g; glycerin 6 g; TEA 0.5 g; methylparaben 0.1 g; propylparaben 0.025 g; 30 ml distilled water and ethanol extract of Bintangur leaf formulation 0% 0 g; formulation 1% 0.5 g; 2% formulation 1 g and 3% formulation 1.5 g. Bintangur leaf ethanol extract mask in formulations F3 and F2 was the highest concentration producing an inhibition zone to inhibit the growth of Staphylococcus aureus and Propionibacterium acnes bacteria which were in the medium category and for formulations F1 and F3 the highest concentrations were to inhibit the growth of epidermal Staphylococcus bacteria which were categorized as The ethanol extract of Bintangur leaf whose antioxidant activity was measured obtained an IC50 value of 9.87 g/mL which was included in the very strong category. The mask of Bintangur leaf extract in the form of the peel-off gel has the potential to be used and marketed.
PENDAMPINGAN PEMBUATAN MASKER PEEL OFF PUCUK KAYU LUBANG Timonius flavescens (Jacq.) Baker MENJADI PRODUK UNGGULAN DESA AIK ABIK Robby Gus Mahardika; Occa Roanisca; Henri Henri; Selvy Aprilia
Martabe : Jurnal Pengabdian Kepada Masyarakat Vol 7, No 1 (2024): MARTABE : JURNAL PENGABDIAN KEPADA MASYARAKAT
Publisher : Universitas Muhammadiyah Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31604/jpm.v7i1.161-165

Abstract

Dusun Aik Abik memiliki potensi tumbuhan obat yang sangat tinggi. Masyarakat masih sering memanfaatkan tumbuhan obat sebagai terapi pengobatan. Tumbuhan kayu lubang (Timonius flavescens (Jacq.) Baker) sering digunakan masyarakat setempat untuk perawatan wajah dan mengobati jerawat. Tumbuhan tersebut dapat dikembangkan menjadi produk turunan masker peel off yang dapat dijadikan sebagai produk unggulan desa. Oleh karena itu, melalui kegiatan pengabdian kepada masyarakat ini tim pengabdi mentransfer inovasi pengolahan pucuk kayu lubang sebagai masker peel off untuk mendukung pemanfatan tumbuhan lokal menjadi produk yang bernilai ekonomi tinggi. Metode yang digunakan pada kegiatan ini berupa sosialisasi dan pendampingan secara langsung kepada mitra sasaran perangkat lembaga adat Dusun Aik Abik dan masyarakat.  Hasil kegiatan pengabdian kepada masyarakat ini adalah mitra sasaran memahami cara formulasi masker peel off berbahan pucuk kayu lubang dan menerima desain kemasan yang telah dicetak oleh tim pengabdi. Komitmen mitra sasaran akan melanjutkan pengembangan masker peel off menjadi produk unggulan Dusun Aik Abik.
Cempedak leaf extract (Artocarpus champeden) as a novel ingredient in antibacterial peel-off gel face masks Putri, Faizah Alivia; Widia, Widia; Syarmila, Syarmila; Mahardika, Robby Gus
Acta Pharmaciae Indonesia : Acta Pharm Indo Vol 10 No 2 (2022): Acta Pharmaciae Indonesia : Acta Pharm Indo
Publisher : Pharmacy Department, Faculty of Health Sciences, Jenderal Soedirman University, Purwokerto, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.api.2022.10.2.4920

Abstract

Background: Phenolic compounds in plants act as natural antioxidants, with cempedak (Artocarpus champeden) leaf extract showing promise due to its high phenolic content and potential antibacterial properties against Propionibacterium acnes. Objective: This study explores the effectiveness of cempedak leaf extract as an active ingredient in peel-off gel face masks for antibacterial purposes. Methods: Cempedak leaf extract was analyzed for phenolic content and Fourier transform infrared (FTIR). Its antibacterial activity was tested against P. acnes using agar diffusion, comparing inhibition zones with positive control. A peel-off gel face mask was formulated with cempedak leaf extract, undergoing physical and an irritation test. Results: Cempedak leaf extract contained a total phenolic content of 342.35 mg EAG/g and exhibited significant antibacterial activity. The face mask formulation with cempedak leaf extract showed promising physical properties and did not irritate, meeting the peel-off gel face mask standards. Conclusion: Cempedak leaf extract has potent antibacterial properties, making it an effective ingredient in peel-off gel face masks for treating acne. Further research could explore its commercial potential in skincare products.
Aktivitas Antioksidan dan Fitokimia dari Ekstrak Etil Asetat Pucuk Idat (Cratoxylum glaucum) Mahardika, Robby Gus; Roanisca, Occa
Indonesian Journal of Chemical Research Vol 5 No 2 (2018): Edisi Bulan Januri (Edition For January)
Publisher : Jurusan Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/ijcr.2018.5-rob

Abstract

Neutralizing free radicals can use both synthetic and natural antioxidant compounds. Although synthetic antioxidant compounds are more active, but lately the use of synthetic antioxidants is being reduced because they are reported to have carcinogenic side effects. Natural antioxidant compounds found in plants are phenolic groups such as flavonoids, tannins, xanthones, and anthraquinones. This compound is widely found in the genus Cratoxylum where one of the species is pucuk idat (Cratoxylum glaucum). Pucuk idat are often used by people of Bangka as a flavoring dish and are believed to be traditional medicine to facilitate breastfeeding, tighten skin, treat fever, cough, and diarrhea. The increasing of antioxidants needs and lots efficacy of pucuk idat, hence this study aims to determine the antioxidant activity of ethyl acetate extract Cratoxylum glaucum. The antioxidant test in this study used the DPPH (Diphenylpicrylhydrazyl) method and vitamin C as a positive control. The results of this study indicate that the extract of ethyl acetate Cratoxylum glaucum has strong antioxidant activity with value IC50 32,213 μg / mL. Phytochemical content itself includes hydroquinone phenols (tannins), flavonoids, and steroids. This shows that ethyl acetate extract Cratoxylum glaucum can be used as natural antioxidant.
Potensi Antibakteri Ekstrak Daging Buah Kelubi (Eleiodoxa conferta) Bangka Belitung Menggunakan Microwave-Assisted Extraction (MAE) Surtina, Surtina; Sari, Ratih Puspita; Zulita, Zulita; Rani, Rani; Roanisca, Occa; Mahardika, Robby Gus
Indonesian Journal of Chemical Research Vol 7 No 2 (2020): Edisi Bulan Januari (Edition for January)
Publisher : Jurusan Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/ijcr.2020.7-sur

Abstract

Antibacterial tests were carried out using ethanol extract of kelubi meat (Eleidoxa conferta), extraction using the Microwave-Assisted Extraction method with a ratio of 2: 20 for 30 minutes at 60 °C. Antibacterial tests using diffusion methods with concentrations of 20%, 40%, 60%, 80%, and 100%; positive control of 0.005% amoxillin and DMSO negative control. Antibacterial test results showed that the inhibition zone of ethanol extract in E. coli bacteria with a concentration of 20% was in the moderate category, for a concentration of 40% including the strong category while the concentration of 60%, 80% and 100% was very strong. The inhibition zone of ethanol extract for the S. aureus bacterium with a concentration of 20% is included in the strong category while the concentration of 40%, 60%, 80%, and 100% is categorized as very strong. From these results it can be concluded that the inhibitory zone in Stapylococcus aureus bacteria is greater than that of E. coli bacteria.
Kapasitas Antioksidan Ekstrak Buah Rukam (Flacourtia rukam) Menggunakan Metode Microwave Assisted Extraction (MAE) Fadiyah, Inas; Lestari, Iin; Mahardika, Robby Gus
Indonesian Journal of Chemical Research Vol 7 No 2 (2020): Edisi Bulan Januari (Edition for January)
Publisher : Jurusan Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/ijcr.2020.7-ina

Abstract

Rukam fruit (Flacourtia rukam) is one of the species spread in Indonesia, specifically Bangka Island. Rukam has a higher phenolic ratio than guava (Psidium guajava). Phenolic compounds have a major role as antioxidants, while antioxidants have the ability to fight free radicals. Therefore a study was conducted to examine the application of secondary metabolites and antioxidant bioactivity of the Flacourtia rukam species using the Microwave Assisted Extraction method. Rukam fruit extract is obtained by using the Microwave Assisted Extraction (MAE) method. While for the antioxidant test using the DPPH method. The test results of antioxidant activity of rukam fruit extract with ethanol solvent were obtained with IC50 value 47.7022 ppm and in rukam fruit extract with acetone solvent IC50 33.1702 ppm obtained using this antioxidant antioxidant powder was very strong.
Potency of Bentonite and Pelawan Wood Active Charcoal as Virgin Coconut Oil (VCO) Purity Improvements Through Free Fatty Acid Binding Utami, Sri Risky; Lidya, Lidya; Afrilia, Mega; Mahardika, Robby Gus
Indonesian Journal of Chemical Research Vol 9 No 3 (2022): Edition for January 2022
Publisher : Jurusan Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598//ijcr.2022.9-mah

Abstract

Virgin Coconut Oil (VCO) is pure coconut oil produced from fresh coconuts and does not contain additional chemicals. VCO has a high lauric acid content which acts as an antibiotic, namely antiviral, antibacterial and antiprotozoal so that VCO can increase the human body's resistance to disease or viruses. Free fatty acid (FFA) levels will significantly affect the quality of VCO. The requirement for maximum fatty acid content in VCO to be suitable for consumption is 0.2%. One of the efforts to reduce the free fatty acid levels of VCO is to use adsorbents such as activated charcoal and bentonite. This study aims to determine the effect of bentonite and activated charcoal of pelawan wood (Tristaniopsis merguensis) enhancers of VCO purity. The results showed that the best reduction in free fatty acids was using bentonite and activated charcoal of wood-furnaced pelawan, which was 0.265, while the best turbidity test result was 0.193.
Antioxidant Capacity Fraction of the Pelawan Stems (Tristaniopsis merguensis Griff) Mahardika, Robby Gus; Fajri, Khairul; Henri, Henri
Indonesian Journal of Chemical Research Vol 10 No 3 (2023): Edition for January 2023
Publisher : Jurusan Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598//ijcr.2023.10-mah

Abstract

The impact of reactions free radical compounds can cause various health problems such as inflammation, aging, and cancer. Therefore, to avoid damage caused by free radicals, the body needs an important substance, antioxidants. Natural antioxidants are more recommended than synthetic antioxidants because synthetic antioxidants must be in accordance with the prescribed dose because they can cause side effects that are harmful to the body. This study aimed to determine the antioxidant activity of the extract and fraction of the Pelawan (Tristaniopsis merguensis Grifft.) stem extract. Antioxidant testing was carried out using the DPPH method on extracts and fractions of Pelawan stem extract (T. merguensis Grifft.). In addition, qualitative phytochemical testing was also carried out on extracts of the stems of Pelawan (T. merguensis). The results of the three solvent fractions, n-hexane, ethyl acetate, and methanol, were positive for flavonoid and phenolic secondary metabolites. Meanwhile, the antioxidant activity in reducing DPPH radicals in the methanol extract fraction of pelawan stems had a very strong activity with an IC50 value of 36.33 g/mL, while the ethyl acetate and n-hexane extract fractions had a very weak antioxidant activity with an IC50 value of 387.43 μg/mL dan 759.88 μg/mL.
PENGARUH SALINITAS TERHADAP PERTUMBUHAN SEL, KONSENTRASI FENOLIK DAN FLAVONOID SPIRULINA PADA MEDIA KULTUR MODIFIKASI WALNE DAN AIR LIMBAH BUDIDAYA IKAN Anggraeni, Anggraeni; Gus Mahardika, Robby; Utami, Eva
Jurnal Harpodon Borneo VOLUME 17 NO.1 APRIL 2024
Publisher : Fakultas Perikanan Dan Ilmu Kelautan Universitas Borneo Tarakan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35334/harpodon.v17i1.5551

Abstract

Spirulina merupakan mikroalga potensial untuk dikultur karena mengandung bahan aktif pada pangan fungsional, seperti pigmen fikosianin, fenolik dan senyawa flavonoid. Pertumbuhan dan produksi senyawa aktif Spirulina optimal apabila dikultur pada media yang mengandung nutrisi yang cukup, terutama nitrogen. Penyerapan nitrogen dipengaruhi oleh salinitas. Penelitian ini bertujuan untuk menganalisis salinitas optimum yang mampu meningkatkan pertumbuhan sel dan senyawa aktif Spirulina. Penelitian dilakukan secara eksperimental laboratoris. Perlakuan salinitas digunakan 6 taraf konsentrasi, yaitu 0, 10, 15, 20, 25, dan 30 ppt. Media kultur dimodifikasi dengan penambahan nutrisi walne dan air limbah budidaya ikan dengan perbandingan 1:1. Parameter yang diamati berupa laju pertumbuhan sel, konsentrasi senyawa fenolik dan flavonoid secara kuantitatif. Hasil penelitian menunjukkan bahwa perlakuan salinitas yang berbeda berpengaruh terhadap laju pertumbuhan, sintesis senyawa fenolik dan flavonoid. Salinitas 30 ppt menghasilkan pertumbuhan sel Spirulina tertinggi dengan jumlah 34.575 unit/mL. Konsentrasi fenolik dan flavonoid yang diberi perlakuan salinitas memiliki konsentrasi yang lebih tinggi dibandingkan tanpa perlakuan salinitas. Peningkatan salinitas memberikan reaksi positif terhadap peningkatan kadar flavonoid, namun menunjukkan reaksi negatif pada kadar fenolik.
Co-Authors Adisyahputra Adisyahputra Adisyahputra Adisyahputra Adisyahputra Adisyahputra Adisyahputra Adisyahputra, Adisyahputra Afrilia, Mega Ajeng Triane Syawila Amanah, Hairil Amelia, Ririn Ana Mardliyah Anggraeni Anggraeni Ary Samsiar Ary Samsiar Benget Harmoko Manik Boy Dian Anugra Sandy Delvia Safitri Dewi Septia Ningsih Dianti Aviliani Eva Utami Fadiyah, Inas Fajar Indah Puspita Sari Fajar Indah Puspita Sari Fajar Indah Puspita Sari Fitri Afriani Fusfita Istiqomah Genta Febri Kusuma Gita Afriza Guskarnali, Guskarnali Henri Henri Henri Henri, Henri Herman Aldila Ila Rosilawati Janiar Pitulima Kasro Daniati khairul fajri, khairul Khoirotul Ummah Khoirotul Ummah Lestari, Iin Lidya, Lidya Liska Liska, Liska Mariam Ulfah Maya Yusnita Megiyo Megiyo Nazrun Nazrun Nina Kadaritna Nosa Mayasani Novianti, Shindi Nur Hidayatiandri Nurhadini Nurhadini Putri, Faizah Alivia Rani Rani RANI RANI, RANI Ristika Oktavia Asriza Roanisca, Occa Sari, Ratih Puspita Selvy Aprilia Sembiring, Rinawati Shakila, Shania Shania Sakhila Sito Enggiwanto Sito Enggiwanto Stefan Marco Rumengan Surtina, Surtina Susanti Susanti Syarmila, Syarmila Utami, Sri Risky Verry Andre Fabiani Widia, Widia Widodo Budi Kurniawan Yopan Pratama Yulia Yulia Zulita, Zulita