Claim Missing Document
Check
Articles

Education of the People of Srimenanti Village Through Print and Social Media During The COVID-19 Pandemic Adisyahputra Adisyahputra; Robby Gus Mahardika
Indonesian Journal of Community Empowerment (IJCE) Vol 1 No 02 (2020): Indonesian Journal of Community Empowerment (November)
Publisher : Fakultas Kewirausahaan Universitas Garut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35899/ijce.v1i02.183

Abstract

The spread of the corona virus is increasingly widespread in several areas of Indonesia including the province of the Bangka Belitung Islands. One area that is very strategic and often traversed by people that may be exposed to the spread of the corona virus is Srimenanti Village, Bangka Regency. Therefore, community service activities were carried out in Srimenanti Village which aims to educate the public about COVID-19 through social media and printed media. This activity is assisted by the team of Real Work Lectures (KKN) Universitas Bangka Belitung 2020. Education is carried out using printed media in the form of posters and banners as well as virtual media in the form of videos which are distributed to the people of Srimenanti Village and distributed through social media. The result of this activity is an increase in public understanding and awareness regarding the prevention and handling of COVID-19.
Sintesis Senyawa Vanilil Metil Keton dan Uji Aktivitas Antiinflamasi terhadap Enzim COX-1 dan COX-2 melalui Analisis In Silico Khoirotul Ummah; Robby Gus Mahardika; Ana Mardliyah
ALCHEMY:Journal of Chemistry Vol 8, No 2 (2020): ALCHEMY: Journal of Chemistry
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/al.v8i2.10863

Abstract

This study reports the synthesis of vanillyl methyl ketone from eugenol through Wacker oxidation and anti-inflammatory activity test toward COX-1 and COX-2 through in silico analysis. Wacker oxidation process was catalyzed by PdCl2 and CuCl2 using DMF solvent under the aerobic condition at room temperature for 48 hours. The product of the synthesis was purified by column chromatography and was characterized by NMR, IR, and MS spectroscopy. Characterization by spectroscopic methods showed that vanillyl methyl ketone was formed with a yield of 45% and vanillin (3%) was produced as a by-product. The anti-inflammatory activity of vanillyl methyl ketone was carried out by molecular docking toward   COX-1 and COX-2 obtained from PDB. The analysis showed that the anti-inflammatory activity and selectivity toward COX-2 of vanillyl methyl ketone was higher than eugenol. This was shown by the low binding energy affinity and the number of hydrogen bonds formed between the vanillyl methyl ketone and the active site of the enzyme. Keywords: eugenol, Wacker, vanillyl methyl ketone, antiinflammatory, in silico Pada penelitian ini dilakukan sintesis senyawa vanilil metil keton dari eugenol melalui oksidasi Wacker serta dilakukan uji aktivitas antiinflamasi terhadap enzim COX-1 dan COX-2 melalui analisis in silico. Proses oksidasi Wacker dikatalisis oleh PdCl2 dan CuCl2 menggunakan pelarut DMF dalam kondisi aerob pada suhu ruang selama 48 jam. Senyawa hasil sintesis dipisahkan menggunakan kolom kromatografi dan dikarakterisasi menggunakan spektroskopi NMR, IR dan MS. Hasil karakterisasi menunjukkan bahwa senyawa vanilil metil keton telah terbentuk dengan randemen sebanyak 45% dan juga dihasilkan senyawa vanillin (3%) sebagai produk samping. Aktivitas antiinflamasi senyawa vanilil metil keton dilakukan dengan docking molekuler terhadap enzim COX-1 dan COX-2 yang diperoleh dari PDB. Hasil analisis menunjukkan bahwa aktivitas antiinflamasi dan selektivitas terhadap COX-2 pada senyawa vanilil metil keton lebih tinggi dibandingkan eugenol. Hal ini ditunjukkan melalui rendahnya afinitas energi pengikatan dan banyaknya ikatan hidrogen yang terbentuk antara vanilil metil keton dengan sisi aktif enzim. Kata kunci : eugenol, Wacker, vanilil metil keton, antiinflamasi, in silico
Pengaruh Salinitas terhadap Kepadatan Populasi dan Konsentrasi Klorofil-a Spirulina pada Media Kultur Modifikasi Walne dan Air Limbah Budidaya Ikan Anggraeni Anggraeni; Eva Utami; Robby Gus Mahardika
EKOTONIA: Jurnal Penelitian Biologi, Botani, Zoologi, dan Mikrobiologi Vol 7 No 2 (2022): Ekotonia: Jurnal Penelitian Biologi, Botani, Zoologi dan Mikrobiologi
Publisher : Department of Biology, Faculty of Agriculture, Fisheries and Biology, University of Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (336.683 KB) | DOI: 10.33019/ekotonia.v7i2.3729

Abstract

Spirulina merupakan mikroalga hijau kebiruan yang mengandung klorofil-a. Kandungan klorofil-a Spirulina sangat dipengaruhi oleh faktor lingkungan pada media kultur, salah satunya salinitas. Salinitas yang optimal dapat meningkatkan kadar pigmen klorofil-a, namun peningkatan kadar salinitas juga memberikan pengaruh negatif pada pertumbuhan Spirulina, karena dapat menghambat proses fotosintesis, respirasi dan penyerapan nutrisi. Tujuan penelitian ini yaitu untuk menganalisis peningkatan salinitas terhadap penyerapan nutrisi media kultur yang dilihat dari kepadatan sel dan konsentrasi klorofil-a. Penelitian dilakukan secara eksperimental laboratoris. Kadar salinitas yang digunakan pada penelitian ini yaitu 0, 10, 15, 20, 25, dan 30 ppt. Media kultur dimodifikasi dengan penambahan nutrisi walne dan air limbah budidaya ikan dengan perbandingan 1:1, dengan waktu kultur selama 20 hari. Hasil penelitian menunjukkan kepadatan sel tertinggi terdapat pada salinitas 30 ppt sebesar 0,635±0,091 dan terendah pada salinitas 0 ppt sebesar 0,293±0,037. Kepadatan sel tertinggi pada semua salinitas rata-rata terjadi pada hari ke-8 hingga ke-10. Konsentrasi klorofil-a tertinggi pada salinitas 10 ppt sebesar 107,153 mg/L dan terendah pada salinitas 25 ppt sebesar 19,684 mg/L. Pada kadar salinitas yang lebih tinggi menghasilkan konsentrasi klorofil-a yang lebih rendah. Berdasarkan penelitian disimpulkan bahwa peningkatan salinitas memberi pengaruh terhadap kepadatan populasi, namun tidak pada konsentrasi klorofil-a Spirulina.
Ekstrak Batang Pelawan (Tristaniopsis merguensis Griff.) sebagai Antibakteri pada Staphylococcus aureus dan Escherichia coli Genta Febri Kusuma; Robby Gus Mahardika; Fajar Indah Puspita Sari
Stannum : Jurnal Sains dan Terapan Kimia Vol 4 No 2 (2022): Oktober 2022
Publisher : Department of Chemistry - Universitas Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33019/jstk.v4i2.3063

Abstract

Currently, diseases caused by infection with pathogenic microorganisms are increasing, this is indicated by the increasing interest in antibacterial substances. This research was conducted on the stem of the pelawan plant (Tristaniopsis merguensis Griff.) with the aim of identifying the secondary metabolites contained in the extract of n-hexane, ethyl acetate, and methanol of the stem of pelawan which have the potential to have antibacterial activity. Determination of the profile of the compounds contained in the extract of pelawan stem using a qualitative phytochemical test. Antibacterial test using disc diffusion method. Phytochemical qualitative test showed positive results in the flavonoid and phenol groups. The results of the disc diffusion antibacterial test on the diameter of the inhibitory zone of the stem extract showed that the methanol extract of the stem against the S. aureus had the greatest inhibition against the bacteria S. aureus at a concentration of 10000 ppm with an average inhibitory power of 8.07 mm and against the bacteria E. coli at the concentration of 10000 ppm. concentration of 10000 ppm with an average inhibition of 8.19 mm.
The Effectiveness of Pandan Sea (Pandanus Tectorius) Cellulose Active Charcoal in Reducing BOD, COD, TSS Level’s in Liquid Waste Tapioca Dianti Aviliani; Fajar Indah Puspita Sari; Robby Gus Mahardika
Stannum : Jurnal Sains dan Terapan Kimia Vol 4 No 2 (2022): Oktober 2022
Publisher : Department of Chemistry - Universitas Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33019/jstk.v4i2.3326

Abstract

Tapioca liquid waste contains high organic substances and suspended solids. This research utilizes the cellulose activated charcoal of sea pandan leaves to adsorb the organic matter content and suspended solids. This study aims to determine the lignin and cellulose content of pandan sea leaves before and after delignification, determine characteristics, determine the optimum mass and optimum efficiency of tapioca wastewater adsorption. Analysis of lignin and cellulose content refers to the Chesson method with a decrease in lignin content of 11.5% to 5.4% as cellulose content increases from 65.1% to 83.6%. The results of the characteristics of water content 11.6% and ash content of 4.2%, GSA analysis showed a surface area of ​​12.6495 m2/g, a total pore volume of 0.0124607 cm3/g which included micropores and an average pore radius of 1.97015 nm. Characterization using FTIR showed cellulose functional groups such as O-H, C-H, CH2, C-O and lignin functional groups, namely aromatic CH. Adsorption was carried out with a mass variation of 1, 5 and 10 grams in 250 ml of tapioca liquid waste for 30 minutes. /L to 5.40 mg/L, TSS 875 mg/L to 9.03 mg/L and optimum efficiency at 10 gram mass with removal of COD 99.64%, BOD 99.81%, TSS 98.94%. The adsorption of cellulose activated charcoal from sea pandan leaves is superior to using microorganisms in tapioca wastewater at PT Sinar Batu Rusa Prima. Further modification is needed in the application of activated charcoal in the waste to produce a colorless filtrate.
Pendampingan Pembuatan Disinfektan dan Pembersihan Lingkungan dalam Upaya Pencegahan Covid-19 di Kelurahan Parit Padang Kecamatan Sungailiat Kabupaten Bangka Occa Roanisca; Robby Gus Mahardika; Nosa Mayasani
Dharma Pengabdian Perguruan Tinggi (DEPATI) Vol 1 No 1 (2021): Mei 2021
Publisher : Fakultas Teknik, Universitas Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (421.316 KB) | DOI: 10.33019/depati.v1i1.2308

Abstract

Parit Padang is a sub-district located in Sungaliat District, Bangka Regency, Bangka Belitung Islands Province. Parit Padang Village is in the middle of the city of Sungailiat, where the spread of covid-19 will spread faster. In order to prevent covid-19, the students of the Parit Padang Community Service Program at Bangka Belitung University conducted socialization on how to make disinfectants and clean the environment. The method of KKN UBB activities is in the form of socialization and direct practice to the target community. The result of the UBB Community Service Program is that the community understands how to prevent COVID-19 by using disinfectants to clean the surface of objects that are often physically contacted, and understand how to make disinfectants. The environmental cleaning activities of Parit Padang were carried out with the residents. The Parit Padang community really welcomes the mutual cooperation activities carried out with UBB KKN students.
Upaya Preventif Masyarakat Srimenanti dari COVID-19 melalui Pembagian Masker dan Handsanitizer Adisyahputra Adisyahputra; Robby Gus Mahardika; Gita Afriza
Dharma Pengabdian Perguruan Tinggi (DEPATI) Vol 1 No 1 (2021): Mei 2021
Publisher : Fakultas Teknik, Universitas Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (252.793 KB) | DOI: 10.33019/depati.v1i1.2311

Abstract

Indonesia is currently being shaken by the COVID-19 pandemic, which has infected thousands of people and even died. The government has given an appeal to the community to reduce the spread of the COVID-19 virus. However, not many people have complied with the government's appeal. Especially in Srimenanti Village, very few people know how dangerous the COVID-19 virus is. Therefore it is necessary to understand the health protocol for breaking the COVID-19 chain. Based on these problems, the authors carry out community service through Real Work Lecture (KKN) activities with the theme COVID-19, the method used to support public safety against COVID-19, namely in the form of distribution of masks and hand sanitizers also educating the public about COVID-19. The results show that people who previously did not care about the pandemic are currently progressing and are more concerned about themselves and those around them. Evidenced by always using a mask and hand sanitizer when leaving the house.
Peningkatan Daya Saing UMKM Kelurahan Sri Menanti Melalui Fasilitasi Perolehan Perizinan Dasar Occa Roanisca; Robby Gus Mahardika; Maya Yusnita
Jurnal Pengabdian Pada Masyarakat Vol 7 No 2 (2022): Jurnal Pengabdian Pada Masyarakat
Publisher : Universitas Mathla'ul Anwar Banten

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (464.851 KB) | DOI: 10.30653/002.202272.52

Abstract

IMPROVING THE COMVETITVENESS OF UMKM IN SRI MENANTI VILLAGE THROUGH FACILITATING THE ACQUISITION OF PRODUCT LEGALITY. Micro, Small and Medium Enterprises (UMKM) have a very strategic role in the people-based economic development in Indonesia. The strengthening of this role must be increased by equipping businesses with permits that have been determined by the Government, such as food safety education certificates, sanitation hygene-worthy certificates, and home industry food production certificates. There are still many UMKM in Sri Menanti Village that do not have these product legality. Therefore, this service activity will facilitate the management of these permits. The method in this service activity is in the form of direct assistance for submissions, facilitation of laboratory testing costs so that all fostered partners obtain these permits. The fostered partners in this activity amounted to seven UMKM determined by the Sri Menanti Village Party. The result of this service activity is that the seven assisted UMKM managed to get these permits. The seven UMKM already have food safety education certificates, two UMKM have received HS-worthy certificates and five other UMKM have received PIRT certificates. Obtaining this license will make it easier for the assisted UMKM to market their products more broadly.
Nanoencapsulation of Simpur (Dillenia indica L.) Leaf Extract For Antibacterial Robby Gus Mahardika; Shania Sakhila; Nurhadini Nurhadini
ALKIMIA Vol 6 No 2 (2022): ALKIMIA
Publisher : SCIENCE AND TECHNOLOGY FACULTY OF UNIVERSITAS ISLAM NEGERI RADEN FATAH PALEMBANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19109/alkimia.v6i2.13675

Abstract

Simpur leaf (Dillenia indica L.) as a traditional medicinal plant spread in the Bangka Belitung Islands. Secondary metabolites contained in simpur leaf extract are alkaloids, flavonoids, phenols, tannins, saponins, steroids, and terpenoids. Compounds that provide pharmacological properties such as polyphenols are unstable to the influence of temperature and high light intensity so that they are easily oxidized. The challenge to protect the damage of these compounds can be done by means of nanoencapsulation. This study aims to determine the size and efficiency of the nanoencapsulation of simpur leaf extract and its antibacterial bioactivity against Staphylococcus aureus and Escherichia coli bacteria. Manufacture of nanoencapsulation using the nanoprecipitation method with the constituent components of PCL (1.5 g), Tween 80 (50 mL), simpur leaf extract (0.15 g; 0.25 g; 0.35 g). Antibacterial activity testing using disc diffusion method. Nanoencapsulated extract mass 0.15 g; 0.25 g; and 0.35 g have sizes of 167.2 nm, respectively; 208.7 nm; and 229.1 nm and encapsulation efficiency of 88.21%; 56.77%; and 5.34%. The antibacterial activity of the nanoencapsulation and extract was more effective in inhibiting the growth of Staphylococcus aureus bacteria than Escherichia coli bacteria. Strength of activity against Staphylococcus aureus bacteria in nanoencapsulated extracts was categorized as moderate to strong and Escherichia coli bacteria in extracts were categorized as moderate.
Synthesis of Diazo Quinolinone Stefan Marco Rumengan; Khoirotul Ummah; Robby Gus Mahardika; Ana Mardliyah; Mariam Ulfah; Ajeng Triane Syawila
Jurnal Kimia Fullerene Vol 8 No 2 (2023): Fullerene Journal of Chemistry
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37033/fjc.v8i2.600

Abstract

Quinolones are important heterocyclic compounds in medicine and materials for DSSC or OLED. This study aims to make a quinolinone framework that has several functional groups. These functional groups can be coupled with various other heterocyclic compounds. The synthesis of the target compound consists of forming a quinolinone framework using phenyldiamine and ethyl aceto acetate via the Penchmann reaction then iodination using ICl. The Penchmann reaction succeeded in forming a quinolinone framework as indicated by shown a proton signal at 11.22 ppm. The iodination reaction was successfully carried out by adding iodo to the benzene ring and the appearance peak of (M+H) m/z was 300.9839 on mass spectroscopy. The compound 7-amino-8-iodo-4-methyl-2-quinolinone (compound 2) has been successfully synthesized. Compound 2 has 3 functional groups (amine, iodo and alkene) that can be used for coupling with the other heterocycles.