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Efek Penggunaan Minyak Kelapa Murni yang Beredar di Pasaran terhadap Nafsu Makan Tikus (Rattus norvegicus
Belinda, Febri Akhmad;
Makiyah, Sri Nabawiyati Nurul
Mutiara Medika: Jurnal Kedokteran dan Kesehatan Vol 8, No 1(s) (2008): April
Publisher : Universitas Muhammadiyah Yogyakarta
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DOI: 10.18196/mmjkk.v8i1 (s).1639
Recently, obesity being public ’s enemy which makes people try to against it effectively, one of the way is by consuming virgin coconut oil to press on appetite. Whether virgin coconut oil can press on rat ’s appetite, needs to be studied. Objectives of this research is to determine effect of market products of virgin coconut oil related to white rat appetite Design of this research is an experimental research in vivo on animal test which uses 20 rats winstar strain 2 months age, 138-212 gram body weight as subject. Rats divided into 4 groups; 3 groups as treatment and 1 group as control. Treatment group given virgin coconut oil from 3 different products per oral in 30 days in converse dosage of human 50cc/hari x 0,018 x rats bodyweight /200 gr. Then measuring the bodyweight each 5 days and measuring the pigswill everyday in 30 days. Result of this research showed that the bodyweight in totally and specially the feed intake in treatment groups lower than control group. It could concluded that virgin coconut oil can decrease the appetite of white rat (Rattus norvegicus) which can be measured from the bodyweight in totally and specially the feed intake.Akhir-akhir ini obesitas menj adi musuh masyarakat, dimana kemudian masyarakat berlomba- lomba untuk melawannya dengan berbagai cara, salah satunya dengan mengkonsumsi minyak kelapa murni untuk menekan nafsu makan. Apakah minyak kelapa murni dapat menekan nafsu makan pada tikus putih perlu diteliti. Tujuan penelitian ini adalah untuk mengetahui efek penggunaan minyak kelapa murni (VCO) yang beredar di pasaran Desain penelitian adalah eksperimental laboratori in vivo pada hewan uj i, menggunakan 20 ekor tikus putih (Rattus norvegicus) galur Wistar usia ± 2 bulan dengan berat antara 138-212 gram. Dibagi menjadi 4 kelompok dengan 3 kelompok perlakuan dan 1 kelompok kontrol. Kelompok perlakuan diasup minyak kelapa murni dengan 3 merek berbeda per oral setiap hari selama 30 hari dengan dosis konversi dari manusia 50cc/hari x 0,018 x berat badan tikus/ 200 gr. kemudian ditimbang berat badannya tiap 5 hari sekali dan ditimbang sisa pakannya setiap hari. Setelah 30 hari kemudian dianalisa. Hasil penelitian menunjukkan bahwa tikus yang diberi perlakuan dengan minyak kelapa murni mempunyai intake pakan dan berat badan lebih rendah dibandingkan dengan kelompok kontrol. Dapat disimpulkan bahwa minyak kelapa murni dapat menurunkan nafsu makan tikus putih (Rattus norvegicus) diukur dari intake pakan dan berat badan secara menyeluruh.
EFEKTIVITAS YOGA DALAM MENGATASI KECEMASAN DAN DEPRESI KEHAMILAN : A SCOPING REVIEW
Sarmin, Sukati;
Makiyah, Sri Nabawiyati Nurul;
Fatmawati, Elis
JURNAL ILMIAH OBSGIN : Jurnal Ilmiah Ilmu Kebidanan & Kandungan P-ISSN : 1979-3340 e-ISSN : 2685-7987 Vol 16 No 1 (2024): MARET
Publisher : NHM PRESS
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DOI: 10.36089/job.v16i1.1914
Psychological disorders can occur during pregnancy and become serious health problems, such as depression and anxiety. Anxiety that occurs simultaneously with depression during pregnancy has a negative impact on the mother and baby. Practicing yoga while pregnant is beneficial as a health improvement and has therapeutic effects on illness, depression, stress and anxiety. This review aims to determine the effectiveness of yoga in treating anxiety and depression during pregnancy. This research method uses the scoping review method with the Arksey and O'Malley framework. Systematic review through PubMed, Willey, ProQuest and Gray Literature databases using predetermined keywords. It was found that 11 of the 562 articles were selected based on inclusion and exclusion criteria. The effectiveness of yoga is described in three themes, namely the effectiveness of yoga in overcoming anxiety, depression and yoga safety. The conclusion of this review states that yoga is effective in reducing depression and anxiety in pregnant women with or without depression.
Pelatihan Keterampilan Observasi Gaya Belajar Dalam Upaya Penanganan Permasalahan Siswa
Tinartayu, Seshy;
Makiyah, SN Nurul;
Suryandari, Galuh;
Kurniawan, Muhammad;
Nafi'ah, Fadila Nurun
Darmabakti : Jurnal Pengabdian dan Pemberdayaan Masyarakat Vol 5 No 02 (2024): Darmabakti : Jurnal Pengabdian dan Pemberdayaan Masyarakat
Publisher : Lembaga Peneliian dan Pengabdian Masyarakat (LPPM) Universitas Islam Madura (UIM)
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DOI: 10.31102/darmabakti.2024.5.02.327-332
This research is based on the importance of the teacher's role in the teaching and learning process such as understanding student characteristics such as learning styles. The purpose of this research is to increase the ability to maximize human resources in students by understanding their learning styles so that they can create an effective teaching and learning environment. This community service was carried out at SMA Muhammadiyah III Yogyakarta which was attended by 41 teachers as participants. The results of this training show that the teacher's view of observing student learning styles increases and has a better understanding of the use of several methods to observe student learning styles, the benefits, and the importance of the teacher's role in maximizing student learning performance.
Comparison of Yam Composite Cookies Sensory Characteristic Between Sugar and Stevia Sweeteners
Makiyah, Sri Nabawiyati Nurul;
Setyawati, Ika;
Rahmadhia, Safinta Nurindra;
Tasminatun, Sri;
Kita, Masaki
Journal of Agri-Food Science and Technology Vol. 5 No. 2 (2024): November
Publisher : Universitas Ahmad Dahlan
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DOI: 10.12928/jafost.v5i2.10211
Yam (Dioscorea alata L.) is one source of carbohydrates with a low glycemic index. It is useful for controlling blood glucose levels. Yam has high carbohydrate and protein content but low sugar content. This research contributed to compare the sensory characteristics of the yam composite cookies between sugar and stevia sweeteners. This research is a quasi-experimental study with a cross-sectional design. Purple yam tubers were made into yam flour. The composite was made from yam flour and green bean flour (F1=100:0; F2= 80:20; F3= 60:40; F4= 40:60; F5= 20:80) (%w/w). Composites were processed into cookies with sugar and stevia sweeteners. Cookies with sugar and stevia sweeteners tested sensory characteristics to 31 in healthy adults aged 25-35. The results showed that the sensory characteristics of shape, size, color, texture, sweet taste and umami taste of yam cookies with sugar sweetener were not better than stevia sweetener. In contrast, the sub-variables of aroma, taste, and overall sweet potato cake with sugar were better than stevia. This implies that yam composite cookies with stevia sweeteners are healthier, but less desirable.
DUKUNGAN SOSIAL DAN MOTIVASI TERHADAP KEPATUHAN PEMBATASAN CAIRAN PASIEN YANG MENJALANI HEMODIALISIS
Sriyati Sriyati;
Sri Nabawiyati Nurul Makiyah
Bhamada: Jurnal Ilmu dan Teknologi Kesehatan (E-Journal) Vol 10 No 2 (2019)
Publisher : UNIVERSITAS BHAMADA SLAWI
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DOI: 10.36308/jik.v10i2.161
Kepatuhan pembatasan asupan cairan merupakan masalah pada pasiengagal ginjal kronik yang menjalani hemodialisis. Ketidakpatuhan menyebabkan kegagalan pengobataan, menurunkan kualitas hidup sehinggameningkatkan morbiditas dan mortalitas. Dukungan sosial dan motivasi marupakan faktor penting dalam kepatuhan pembatasan asupan cairan.Tujuan penelitian ini untukmemberikan gambaran tentang dukungan sosial dan motivasi dengan kepatuhan pembatasan asupan cairan pada pasien gagal ginjal kronik yang menjalani hemodialisis. Desain: Literature review.Metode:Penelusuran menggunakan database dari Jurnal, literatur review melalui Pub-Med, Google Scholar, ProQuest sesuaikriteria inklusi dan dipublikasikan dalam reviewjurnal. Beberapa istilah kata kunci yang menyerupai digabungkan untuk mendapatkan hasil pencarian yang tepat kemudian hasil dianalisis, dibahas dan disimpulkan. Hasil: Penelusuran menghasilkan beberapa artikel dan ada tiga artikel yang memenuhi kriteria inklusi. Pengumpulan data dari sampel menggunakan kuesioner dan atau wawancara yang semuanya membahas tentang ketidakpatuhan asupan cairan.Kesimpulan:Kepatuhan pembatasan asupan cairan pada pasien yang menjalani hemodialisis perlu diperhatikan agar pasien dapat menjalani hidup dengan nyaman dan tidak terjadi komplikasi yang tidak diharapkan. Menjaga self efficacy positifperlu ditekankan secara terus menerus untuk pengelolaan terapi yang baik, dimana pasien benar-benar diberi tanggung jawab untuk pengendalian pengobatan. Untuk menghasilkan tingkat kepatuhan yang optimal pasien perlu mendapatkan dukungan sosial baik dari keluarga, tim pelayanan kesehatan, teman senasib dan masyarakat sekitarnya. Motivasi yang muncul dari diri pasien perlu mendapatkan dukungan yang baik dari semua pihak.
The immunomodulatory activity of dioscorea alata on spleen histology of rats induced with 50% alcohol
Makiyah, Sri Nabawiyati Nurul;
Zahra, Adelia Nabilah
Science Midwifery Vol 13 No 1 (2025): April: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)
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DOI: 10.35335/midwifery.v13i1.1865
Dioscorea alata is frequently consumed and has several health advantages. The immune system-protecting spleen may be protected by bioactive substances in Dioscorea alata tubers. This study examined the influence of immunomodulatory ethanol extract of Dioscorea alata (EEDA) on the diameter of the white pulp of the spleen in 50% alcohol-induced rats (Rattus norvegicus). This research is quasi-experimental using post-test only controlled group design. Twenty-five Rattus norvegicus were separated into five groups. The normal control group (C) received Carboxymextyl Cellulose (CMC), the negative control group (NC) received CMC and 50% alcohol, and three groups received EEDA at doses of 50, 250, and 500 mg/kg for 14 days and 50% alcohol. The diameter of the white pulp of the spleen data analyzed with Kruskal-Wallis and Mann-Whitney tests. The study found a significantly increase in the diameter of the white pulp of the spleen (p<0.05) in the negative control group, EEDA doses of 50 and 250 mg/kg. The control group and EEDA doses 500 mg/kg groups had smaller the diameter of the white pulp of the spleen. The conclusions of this research proved that EEDA has an immunomodulatory activity, EEDA was immunostimulant at doses 50 and 250 mg/kg and immunosuppressant at doses 500 mg/kg.
The Barriers To Exclusive Breastfeeding: A Case-Control Study Among Mothers In Gorontalo City, Indonesia
Sarmin, Sukati;
Makiyah, Sri Nabawiyati Nurul;
Rokhanawati, Dewi
Jurnal Kesehatan Manarang Vol 9 No 3 (2023): December 2023
Publisher : Politeknik Kesehatan Kemenkes Mamuju
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DOI: 10.33490/jkm.v9i3.890
Exclusive breastfeeding is one of the important contributions to reducing maternal mortality, infant mortality, economic and environmental benefits. However, mothers still face many barriers during exclusive breastfeeding. This study aims to explain the perceived barriers to breastfeeding and find the most dominant barriers to breastfeeding. This type of research is quantitative research with analytic observational design and case-control method. The number of respondents in this study was 86 breastfeeding mothers, with a division of 43 mothers into case groups and 43 mothers into control groups. Sampling was determined by simple random sampling technique using an online number randomization application, namely random generator. Data were obtained from an original survey using an online questionnaire distributed through a social media platform in the form of a google form link. The results showed that barriers to exclusive breastfeeding from the social aspect, namely inadequate support from health care providers, were the most visible, followed by barriers from the maternal and infant aspects. Lack of health worker support (AOR= 22.621) was considered the main barrier to exclusive breastfeeding for six months among mothers in Gorontalo City, Indonesia. This was followed by lack of knowledge on breastfeeding. The lowest barrier was family support. Research on barriers to exclusive breastfeeding can help nurses and midwives develop breastfeeding promotion programs to increase exclusive breastfeeding among women in Gorontalo City, Indonesia.
Pengaruh Konseling terhadap Perubahan Sikap dan Perilaku Pencegahan Anemia pada Ibu Hamil Trimester I di Puskesmas Semanu 1 Gunungkidul
Wulandari, Estiyani;
Makiyah, Sri Nabawiyati Nurul;
Anjarwati, Anjarwati
MAHESA : Malahayati Health Student Journal Vol 3, No 7 (2023): Volume 3 Nomor 7 (2023)
Publisher : Universitas Malahayati
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DOI: 10.33024/mahesa.v3i7.10436
ABSTRACT One of the maternal mortality causes in Indonesia is anemia. The higher number of anemia incidence in pregnant women signals a prevention such as by counselling for pregnant women. The study is to analyse the effect of counselling on attitude change and anemia prevention behaviour in trimester 1 pregnant women at Semanu 1 primary health centre of Gunungkidul in 2019. The type of the study was mixed method and the design was sequential explanatory and one group pre-test – post-test. The sampling technique was purposive sampling. The quantitative instrument was questionnaire on attitude and behaviour of anemia prevention and the data were analysed using paired t-test and linear regression. The qualitative instrument was interview guidelines. Counselling was given at Semanu 1 primary health centre by using elective counselling method through anemia feedback form for pregnant women. Pre-test on attitude and behaviour was given before counselling and post-test was given 1 week after counselling.The result of the study showed that attitude and anemia prevention behaviour in pregnant women was improving after counselling. The attitude mean value before and after counselling was 4.250 and the behaviour mean value improvement before and after counselling was 1.625. The conclusion of the study is that there is an effect of attitude and behaviour of anemia prevention in trimester 1 pregnant women after counselling. It is hoped that the results of this study can be used as a reference for the implementation of antenatal care (ANC), especially providing counselling in the management of anemia prevention in pregnant women. Keywords : Counselling, Attitude, Behaviour, Anemia. ABSTRAK Salah satu penyebab kematian ibu di Indonesia adalah anemia. Semakin meningkatnya kejadian anemia pada ibu hamil maka perlu dilakukan upaya pencegahan anemia salah satunya adalah pemberian konseling pada ibu hamil. Penelitian ini bertujuan untuk mengetahui pengaruh konseling terhadap perubahan sikap dan perilaku pencegahan anemia pada ibu hamil Trimester I di Puskesmas Semanu 1 Gunungkidul tahun 2019. Jenis penelitian adalah mixed method (campuran). Desain penelitian adalah sequential explanatory. Rancangan penelitian yang digunakan adalah one group pre test – post test. Teknik pengambilan sampel menggunakan purposive sampling. Instrumen kuantitatif menggunakan kuesioner sikap dan perilaku pencegahan anemia, dianalisis menggunakan uji pair t- test dan uji regesi linear, instrumen kualitatif menggunakan pedoman wawancara. Konseling diberikan di Puskesmas Semanu I dengan metode ellective counselling menggunakan panduan lembar balik anemia pada ibu hamil. Pre test sikap dan perilaku diberikan sebelum konseling, dan post tes diberikan 1 minggu setelah konseling. Hasil penelitian ini menunjukkan bahwa sikap dan perilaku pencegahan anemia pada ibu hamil mengalami peningkatan setelah konseling, dengan peningkatan nilai rata-rata sikap sebelum dan setelah konseling sebesar 4.250, peningkatan nilai rata-rata perilaku sebelum dan setelah konseling sebesar 1.625. Simpulan dari penelitian ini adalah ada pengaruh sikap dan perilaku pencegahan anemia pada ibu hamil trimester I setelah diberikan konseling. Diharapkan hasil penelitian ini dapat dijadikan sebagai acuan pelaksanaan antenatal care (ANC) khususnya pemberian konseling dalam pengelolaan pencegahan anemia pada ibu hamil. Kata Kunci: Konseling, Sikap, Perilaku, Anemia
Ovalbumin's potential as a wound-healing medicament in tooth extraction socket by induction of cell proliferation through the ERK2 pathway in silico
Makiyah, Sri Nabawiyati Nurul;
Puspita, Sartika
Dental Journal (Majalah Kedokteran Gigi) Vol. 56 No. 3 (2023): September
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en
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DOI: 10.20473/j.djmkg.v56.i3.p144-153
Background: The trend of studies on dental medicaments is increasing rapidly. Antibacterial or anti-inflammatory activity is most frequently studied. Ovalbumin is one of the proteins whose benefits have been studied, but these benefits are still limited because of ovalbumin's potential for proliferative bioactivity. Purpose: The aim of this study is to examine ovalbumin's potential as a woundhealing medicament through molecular docking analysis on a protein related to the extracellular signal-regulated kinases/mitogenactivated protein kinase (ERK/MAPK) signaling pathway. Methods: Ovalbumin was hydrolyzed through BIOPEP-UWM (The BIOPEPUWMâ„¢ database of bioactive peptides). Protein target and interaction were predicted using Similarity Ensemble Approach target prediction webserver, SuperPred webserver, STRING webserver, and Cytoscape version 3.9.1. Selected fragments were docked using Autodock Vina in PyRx 0.8 with Tukey's multiple comparison test and Biovia Discovery Studio version 19.1.0.18287 for visualization. Results: This study found that ovalbumin has the potential to positively regulate cell proliferation, angiogenesis, and fibroblast growth factor production. Six of the 131 fragments of ovalbumin could interact with 73 proteins, and the 20 proteins with the highest probability and score of betweenness centrality showed potential for bioactivity. Five fragments and povidone-iodine interacted inside the Adenosine triphosphate (ATP) phosphorylation site of ERK2, whereas fragment 1 (F1) and glycerin interacted outside the site. F1 could decrease the binding energy required for adenosine 5"²-[,-methylene]triphosphate or an ATP-analogue chemical compound to interact with ERK2 compared to the control, with a score that was not significant. Conclusion: Ovalbumin has the potential to induce cell proliferation by affecting ERK2-ligand interactions.
MEMBANGUN PERILAKU SEHAT: EDUKASI DAN PRAKTIK CUCI TANGAN UNTUK MENCEGAH PENYAKIT KECACINGAN
Makiyah, Sri Nabawiyati Nurul;
Kesetyaningsih, Tri Wulandari;
Istianah, Siti
JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai Vol. 10 No. 1 (2025): JURNAL PENGABDIAN MASYARAKAT RUWA JURAI
Publisher : FK Unila
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DOI: 10.23960/jpmrj.v10i1.3493
Anak usia sekolah rentan terhadap infeksi cacing akibat rendahnya kebersihan tangan dan kuku. Kegiatan pengabdian ini bertujuan meningkatkan pengetahuan siswa tentang penyakit kecacingan dan perilaku hidup bersih dan sehat (PHBS) melalui edukasi dan praktik mencuci tangan. Kegiatan dilakukan di SD Muhammadiyah Tengahan, Sleman, dengan metode penyuluhan. Rangkaian kegiatan diawali dengan pretes, penyuluhan dengan media audiovisual, diskusi, praktik kebersihan, dan postes. Sebanyak 110 siswa sekolah dasar Muhammadiyah Tengahan mengikuti kegiatan ini. Hasil pemeriksaan kuku menunjukkan masih ditemukannya kista Balantidium coli pada kuku siswa. Hasil uji t menunjukkan adanya peningkatan signifikan pengetahuan tentang PHBS setelah pemberian penyuluhan (p<0,05). Edukasi kesehatan terbukti efektif dalam meningkatkan kesadaran siswa terhadap pencegahan penyakit kecacingan dengan sosialisasi tentang penyakit kecacingan dan PHBS.