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All Journal Journal of Food and Pharmaceutical Science Indonesian Journal of Pharmaceutical Science and Technology STOMATOGNATIC- Jurnal Kedokteran Gigi JURNAL PHARMASCIENCE Majalah Obat Tradisional INDONESIAN JOURNAL OF PHARMACY Acta Pharmaciae Indonesia : Acta Pharm Indo Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Majalah Farmaseutik Indonesian Journal of Chemistry JSFK (Jurnal Sains Farmasi & Klinis) Journal of Herbal, Clinical and Pharmaceutical Science (HERCLIPS) Jurnal Farmasi Sains dan Praktis Jurnal Farmasi Indonesia Journal of General Procedural Dermatology and Venereology Indonesia Journal of Food and Pharmaceutical Sciences
Ronny Martien
Departement of Pharmaceutics, Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, Sekip Utara Yogyakarta 55281, Indonesia
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Physics Public Health

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ANTIOXIDANT ACTIVITY OF INDONESIAN BROWN MARINE ALGAE (Sargassum turbinarioides) Artemisia, Rahma; Sinurat, Ellya; Setyowati, Erna Prawita; Martien, Ronny; Nugroho, Akhmad Kharis
Jurnal Farmasi Sains dan Praktis Vol 11 No 3 (September-December 2025)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v11i3.9673

Abstract

Brown marine algae are provided for an excellent source of bioactive compounds especially fucoidan. Fucoidan is primarily composed of L-fucose residues linked by α-1,3 and α-1,4 glycosidic bonds, with sulfate groups as its main chemical components. One of the biological activities of fucoidan is antioxidant. Antioxidant activities of Indonesian brown marine algae were investigated. The phytochemical screening of the crude extract was conducted to identify various phytochemical constituents, including carbohydrates, flavonoids, phenolic compound, terpenoids, and proteins and amino acid. The antioxidant activity of the brown marine algae Sargassum turbinarioides was evaluated using free radical scavenging through the DPPH assay and a reducing power assay. The antioxidant capacity of the extracted fucoidan was measured against ascorbic acid, revealing that fucoidan from brown marine algae exhibited lower DPPH radical scavenging activity compared to vitamin C. Meanwhile, the reducing power of the extract increased with higher concentrations, demonstrating a dose-dependent effect. These findings suggest that brown marine algae extract has potential for commercialization as a functional food or dietary supplement owing to its significant antioxidative properties.
Co-Authors Abdul Rohman Adhyatmika, Adhyatmika Agung Endro Nugroho Akhmad Kharis Nugroho Anggriani, Firhani Artemisia, Rahma Artemisia, Rahma Dewi, Siska Noviana Endang Lukitaningsih Erna Prawita Setyowati Fajar Waskito He Yeon Asva Nafaisa Hilda Ismail, Hilda Iis Wahyuningsih Irawan, Muhamad Bayu Irnawati Irnawati Kusumadewi, Awal P. Lina Winarti Lutfi Chabib, Lutfi Madarina Julia Nakhil, Umaimatun Ningrum, Karina Primatyas Novitasari, Laras Nugroho, Akmad Kharis Nuri Ari Efiana Nuryanti Nuryanti Perkasa, DP Pradana, Theophani Bagas Rohmat Mujahid, Rohmat Rony, Zahara Tussoleha Sinurat, Ellya Sismindari . Siti Fatmawati Fatimah, Siti Fatmawati Sofia Mubarika Haryana Styawan, Anita A. Sugiyanto - Sumadi, Firasti A.N Tri Rini Nuringtyas Triana Hertiani wardana, Tirta Yuswanto, Ag