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Leaf Extract Microencapsulation of Stevia rebaudiana Bert Using Inulin-Chitosan as Anti-Diabetes Diet Mutmainah Mutmainah; Yohanes Martono; Ika Puspitaningrum; Lia Kusmita
Journal of Tropical Pharmacy and Chemistry Vol. 5 No. 3 (2021): J. Trop. Pharm. Chem.
Publisher : Faculty of Pharmacy, Universitas Mulawarman, Samarinda, Indonesia, 75117, Gedung Administrasi Fakultas Farmasi Jl. Penajam, Kampus UNMUL Gunung Kelua, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jtpc.v5i3.270

Abstract

Diabetes mellitus is a collection of symptoms that arise in someone who has increased blood glucose levels. The Stevia plant (Stevia rebaudiana Bert) contains a compound of diterpene glycosides as steviosida and rebaudiosida A. Purified extract of steviosida and rebaudiosida A is widely used as a sweetener for low calorie food and beverage products or as a sugar substitute for diabetics and has the effect of lowering blood sugar levels. This study aims to determine the antidiabetic effect of microencapsulated preparations of Stevia leaf extract (Stevia rebaudiana) with a combination of inulin chitosan encapsulation. Antidiabetic mellitus test was carried out in vivo using test animals of male white rats of Wistar strain. The inducing compound that can cause the condition of diabetes mellitus test animals is Aloxan with a dose of 150 mg / kg Body weight of rats. given intraperitoneally for one day, then the mice were allowed to stand for 3 days to reach a state of diabetes mellitus. Blood glucose levels of test animals were measured on days 1 (initial), 5 (induction) and 12 (treatment) to determine the initial blood glucose levels, after induction of alloxan and after administration of test compounds both CMC Na 0.5% , glibenclamide, and preparations microencapsulation of Stevia leaf extract at a dose of 100; 300; and 700 mg / kg body weight. The results were obtained after 7 days of treatment, it was seen that blood glucose levels in the CMC group remained high, while the Glibenclamid administration group, and the three dosages of microencapsulation preparations of Stevia leaf extract could reduce blood glucose levels. This can be seen from the statistical test that there is a significant difference (p
Combination of polyherbal Phyllanthus reticulatus with Zingiber officinale and Cymbopogon citratus to optimize the antioxidant capacity Kristiani, Elizabeth Betty Elok; Kasmiyati, Sri; Martono, Yohanes
Pharmaciana Vol. 14 No. 1 (2024): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v14i1.28002

Abstract

Currently, the public is interested in polyherbal-based foods and beverages as a source of natural antioxidants. The aim of the study is to evaluate the antioxidant properties and the phenolic and flavonoid compounds of formulations containing Z. officinale, C. citratus, and P. reticulatus (ZCP). Each sample was extracted using the maceration process in an ethanol solvent at room temperature for three 72-hour periods. There were fourteenth formulation of Z. officinale rhizome, C. citratus leaves, and P. reticulatus fruit which used Design of Expert (DoE). The DPPH method was used to determine the power of antioxidants. The flavonoid content of the extract was measured using the colorimetric method and AlCl3 reagent, while phenolics content using Folin-Ciocalteu. The formulations ZCP 1:0:0, 0:0:1, and 1:1:1 showed the antioxidant capacity in a strong categorization, with an IC50 value less than 50 µg/ml, while ZCP 0:1:0 was in a weak categorization (IC50 > 250 µg/ml). Another ZCP formulation was in a medium category. The ZCP 1:1:1 formulation was suggested as the best one for this investigation, which contains three plant samples. This formulation is interesting for further toxicity studies and in vivo testing so that it can be applied as an antioxidant-rich supplement product.
Synthesis and Characterization of Nano Activated Carbon Tea Waste (Camellia sinensis L.) Viewed from the Content and Ratio of Orthophosphoric Acid Wijaya, Daniel Ricky Putra; Martono, Yohanes; Riyanto, Cucun Alep
INDONESIAN JOURNAL OF CHEMICAL RESEARCH VOLUME 3, ISSUE 2, 2018
Publisher : Chemistry Department, Universitas Islam Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (567.07 KB) | DOI: 10.20885//ijcr.vol3.iss2.art2

Abstract

Waste of tea is still limited in terms of utilization, potentially to be made into nanocarbon. In this research, nanocarbon synthesis from the waste of tea through carbonation method using furnace and purification with HNO3 with activator substance used is H3PO4. The specific objective of this study was to determine the optimal levels and ratios of ortho-phosphoric acid and to determine the properties and characteristics of nanocarbon from tea waste. Based on the FT-IR spectra, the best ortho-phosphate acid levels and ratios are 50% and 1:2 (w/w) H3PO4. The XRD analysis showed that the activated carbon dregs obtained were C graphite which was characterized by the diffraction peak at 2theta: 26.2°; 26.5°; 42.2°; 42.4°; and 44.3°. Based on the TEM image obtained shows that the activated carbon of the resulting tea waste has a particle size of 20-40 nm.
Studi Optimalisasi Perparkiran dan Pedestrian di Fakultas Teknik Jurusan Sipil Universitas Lampung Nawawi, Sherly Novita Sari; Sulistyorini, Rahayu; Martono, Yohanes
Jurnal Rekayasa Sipil dan Desain (JRSDD) Vol. 3 No. 1 (2015): Edisi Maret 2015
Publisher : Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jrsdd.v3i1.395

Abstract

Faculty of Civil Engineering Department as one of the majors at the University of Lampung whichhas the number of students, faculty and others are quite large, this has resulted in demand forparking at the Faculty of Engineering Department of Civil is a problem that can not be ignoredbecause of the Faculty of Civil Engineering Department as a center of community activityacademic need a good arrangement and the campus community college population continues toincrease each academic year. This study aims to investigate the characteristics of the motorvehicle users both motorcycles and cars in the Faculty of Engineering Department of Civil,knowing parking needs in the Faculty of Engineering Department of Civil, find out if parking andpedestrian facilities in the Faculty of Engineering Department of Civil been sufficient,, analyzeparking management solution and pedestrian in the Faculty of Civil Engineering Department.Characteristics of motor vehicle users both motorcycles and cars derived from a comparisonbetween the accumulation of the highest parking vehicles with the number of parking spacesavailable, vehicle car I is 14 pieces of land, land second car that is 20 pieces, motorcycle land I is20 pieces, motorcycles land II is 27 pieces, motorcycles III, 11 pieces of land and land motorcycleIV is 4 pieces. Based on a survey and analysis parking requirements for the Faculty ofEngineering Department of Civil to cars I and II land at 192% / day, for the motorcycle land I of11.2% / day, for the motorcycle land II, III and IV of 126% / day .Keywords: Transportation, Parking, Pedestrian
Analisis Kemacetan Lalu Lintas Sepanjang Jalan Z.A. Pagar Alam Dengan Metode Manual Kapasitas Jalan Indonesia (Studi kasus segmen Universitas Lampung sampai dengan Mall Boemi Kedaton) Novitasari, Shartyka; Martono, Yohanes; Putra, Sasana
Jurnal Rekayasa Sipil dan Desain (JRSDD) Vol. 7 No. 1 (2019): Edisi Maret 2019
Publisher : Universitas Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jrsdd.v7i1.1145

Abstract

Road facilities aim to accomodate existing traffic volumes the designing is also adjusted to traffic characteristic. However, in fact, the comfort level has not meet the requirements of the guide book. This problem is indicated by the slowing down of passing vehicles, the long traffic jam that makes road density this research, simulated to compare vehicles volume and the road capacity along the research road, analysis the level of service catagory based on the road density, predicted the time traveled of the traffic and accomodated by types of road, degree of saturation and speed allowed.  Based on the date analysis the highest traffic jam for traffic volume is in Purnawirawan, then after the analysis of capacity, the highess road density is in University of Lampung, the underpass project for the degree of saturation the analysis is compared with the on the spot real time date. And the result is the highest traffic jam is in underpass project in University of Lampung wich is the real time distance traveled is more density than the distance allowed.  In conclusion, we need to review the geometric design of road, because the geometric design of road is really affect traffic jam. And we have to re-announced about public transportation, so the vehicles volume will decrease. Keywords: traffic volumes. Degree of saturation, speed, road capacity..
THE EFFECT OF TEMPE FERMENTATION TIME ON THE TOTAL PHENOLIC AND ISOFLAVONE GENISTEIN CONTENTS Suharto, Kiki Fransiska; Soetjipto, Hartati; Martono, Yohanes
ALCHEMY Jurnal Penelitian Kimia Vol 13, No 2 (2017): September
Publisher : UNIVERSITAS SEBELAS MARET (UNS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/alchemy.13.2.5094.228-238

Abstract

The objective of this study was to evaluate total phenolic compounds and isoflavone genistein contents during 0 - 9 days of fermentation time. Isoflavone extract were obtained by maceration and fractionation. Total phenolic compounds were measured by Folin ciocalteau method, meanwhile, the isoflavone genistein contents were analyzed by a High Performance Liquid Chromatography. The yield of isoflavone extract and the total phenolic compounds were analyzed using a randomized completely block design and the mean between treatments was compared by the Honestly Significant Difference (HSD) test using significance level of 5 %. The highest amount of total phenolic compounds during the incubation time was obtained on 4 days of fermentation time, i.e., 232.05n ± 7.71 μg/g, while the highest content of isoflavone genistein was obtained on 5 days of fermentation time, i.e., 100.48 μg/g. This research confirms that the fermentation process of tempe induces the total phenolic contents and the production of isoflavone genistein is fluctuating.
Produksi Video Edukasi Partisipatif: Implementasi Service-Learning Mahasiswa DKV UKSW dalam Literasi Kesehatan Masyarakat di Dusun Kendal, Kabupaten Semarang Michael Bezaleel; Desi Desi; Debora Natalia Sudjito; Rully Adi Nugroho; Novriest Umbu Walangara Nau; Yohanes Martono; Desti Christian Cahyaningrum
Karunia: Jurnal Hasil Pengabdian Masyarakat Indonesia Vol. 5 No. 1 (2026): Maret : Karunia: Jurnal Hasil Pengabdian Masyarakat Indonesia
Publisher : Fakultas Teknik Universitas Maritim AMNI Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58192/karunia.v5i1.4183

Abstract

Higher education institutions are increasingly expected to provide tangible solutions to social dynamics through the integration of curricula with Service-Learning (S-L) programs. This article documents the integration of a Cinematography course with the S-L concept to address the low level of environmental health literacy in Dusun Kendal, Semarang Regency. Three major environmental health issues were identified in the area: waste burning, pesticide spraying without the use of personal protective equipment (PPE), and the presence of flies caused by cattle sheds located close to residential areas. Using a three-day live-in method and a participatory video approach, 42 Visual Communication Design students from Satya Wacana Christian University collaborated with local residents to produce educational media. The outcomes of this program consisted of four educational videos addressing issues of waste management, fly pest control, and the use of PPE for farmers. The findings indicate that participatory video is effective as an educational instrument due to its sociocultural proximity to local audiences. In addition to benefiting the community, the program successfully transformed students’ paradigms from merely aesthetic content creators into social communicators who possess empathy and moral responsibility toward humanitarian issues.
Co-Authors A. Rindang Anggit Laksono Abdul Rohman Agung Rimayanto Gintu Agung Rimayanto Gintu Agung Rimayanto Gintu Agung Rimayanto Gintu Agung Rimayanto Gintu Andreas Setiawan Andriyani Rosita Sari Anggelia Essi Christian Ari Hasna Widyapuspa Bereka Meidelivia Raharjianti Betsy Felita Betsy Felita Cucun Alep Riyanto Debora Natalia Sudjito Desi, Desi Desti Christian Cahyaningrum Devina Intan Sari Devinta Lestari Dewi Kurnianingsih Arum Kusumahastuti Diyonisio Kevin Elisando Eliana Prabalaras Elisabeth Betty Elok Kristiani Elizabeth Betty E. Kristiani Elizabeth Betty Elok Kristiani Erlien Giovani Soeroso Fahmi Puteri Perdani Ferdy Semuel Rondonuwu Fidelia Novitasari Fransiskus Tri Wahyu Hananto Franyoto, Yuvianti Dwi Harry Setiawan Hartati Soetjipto Hartati Soetjipto Hindra, Ronal Febria Ida Suskawati Ika Puspitaningrum Ika Puspitaningrum Ira Tyas Kurniasari Kusmita Kusmita Lia Kusmita Lucia Devi Danriani Lydia Ninan Lestario Maria Endah Retno Palupi Michael Bezaleel Wenas Muhamad Syaiful Ampri Mutmainah Mutmainah Mutmainah Mutmainah Mutmainah Mutmainah Nawawi, Sherly Novita Sari November Rianto Aminu Noviana Gunawan Novitasari, Shartyka Novriest Umbu Walangara Nau Nur Ayu Hidayati Rahayu Sulistyorini Rahayu Sulistyorini Rema Fitriyani Rully Adi Nugroho Salsabila Eka Ghina Rana Sandra Ayu Apriliyani Sasana Putra, Sasana Sekar Nurani Saptaningtyas Sherly Novita Sari Nawawi Slamet Widodo Sri Hartini Sri Hartini Sri Kasmiyati Sudibyo Martono Sudibyo Martono Sugeng Riyanto Suharto, Kiki Fransiska Suryasatriya Trihandaru Susanti Pudji Hastuti Tiffany Febetania Widodo Tonia Nur Fitria Widhi Nugroho Meindra Wijaya, Daniel Ricky Putra Yayi Suryo Prabandari Yoko Putra Nusantara Yuniarti, Zulfa Zulfa Yuniarti