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All Journal Diponegoro Law Journal Journal of Agromedicine and Medical Sciences Pharmascience Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Journal of Health Promotion and Behavior Buletin Poltanesa Jurnal Industri Pariwisata Jurnal Rekonstruksi dan Estetik Jember Medical Journal (JMJ) International Journal of Health and Information System (IJHIS) Jurnal Otorinolaringologi Kepala dan Leher Indonesia (JOKLI) Folia Medica Indonesiana Jurnal Veteriner

Laksmi Indreswari

Anatomi, Universitas Jember

Author-ID : 3307493

Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Library & Information Science Medicine & Pharmacology Neuroscience Public Health Social Sciences Veterinary

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Sinonasal Bone Destruction caused by Frontal Meningioma Invasion related with Respiratory Tract Infection Incident: A Case Report Adji, Novan Krisno; Putri, Komang Yunita Wiryaning; Indreswari, Laksmi; Nugraha, Muhammad Yuda
Jember Medical Journal Vol. 1 No. 1 (2022)
Publisher : Faculty of Medicine, University of Jember

Meningioma is uncommonly found in extracranial. Extracranial meningioma can be extension from primary intracranial tumors that accompany osteolytic changes in the skull or causes bone destruction. In this article, we report about intracranial meningioma in the frontal region that extend to the sinonasal bone causes bone destruction and being predisposing factor for respiratory tract infection. A 47-years old female brought to the emergency department due to dyspnea and fever since a week ago and there was found a lump in the frontal region. During the surgical procedure, there was invasion of tumor and caused sinonasal bone destruction. The endotracheal tube (ETT) can be seen from the surgical field. In this case the patient was threated pneumonia infection, it can be related as complication of sinonasal bone destruction that caused by invasion of meningioma to extracranial manifestation. The clinical important that must be informed to the patient the possibility of recurrent respiratory tract infection incidents.

Physical Water Quality and Intestinal Protozoa Contamination on Household Water in Ajung District, Jember Regency Dicky Setiawan; Wiwien Sugih Utami; Laksmi Indreswari; Yunita Armiyanti; Bagus Hermansyah
Jember Medical Journal Vol. 1 No. 1 (2022)
Publisher : Faculty of Medicine, University of Jember

Intestinal protozoa infections are still a major health problem in worldwide. The prevalence of intestinal protozoa infections are relatively high in countries facing lack of safe drinking water and lack of suitable sanitation facilities. Lack of sanitation facilities, open defecation, and contamination of environmental feces can make water quality worse, both in terms of physically, chemically, and biologically. Physical water quality is poor when the household water used daily does not meet the standard parameters of the physical water quality standard. The purpose of this study was to determine the relationship between physical water quality and intestinal protozoa contamination in household water in Ajung District, Jember Regency. This type of research is an observational analytic study with a cross sectional research design. The research method used is the correlation method, namely the relationship between physical water quality and intestinal protozoa contamination in household water. The population in this study is household water in Ajung District, Jember Regency. Data analysis consisted of univariate analysis to see the distribution and percentage of temperature, total dissolves solid, color, odor, and intestinal protozoa contamination in household water, and then bivariate analysis using the Chi-square test to analyze physical water quality and intestinal protozoa contamination. The conclusion is there is a relationship between physical water quality and intestinal protozoa contamination in household water.

Extraction of Air Gun Pellet in Lung Base Thoracic Vertebrae Region with Lateral Extracavitary Approach: A Case Report Adji, Novan Krisno; Putri, Komang Yunita Wiryaning; Indreswari, Laksmi; Nugraha, Muhammad Yuda; Habibi, Ali
Jember Medical Journal Vol. 2 No. 2 (2023)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/jembermedicaljournal.v2i2.452

Thoracic gunshot injuries are associated with significant morbidity and mortality, but fatal accidents from air guns are rare. Surgery in this area is challenging, especially if the gun pellet penetrates the visceral organ like the lung. In this case, we present a case of an 18-year-old male who came to the emergency department with an air gunshot (pellet) that penetrated the chest and settled in the lung base. After being shot by an air gun, the patient came with pain in the right back and weakness in both lower extremities. Based on the radiological examination, metallic corpus allienum measuring ± 0.8 x 0.7 cm has shown at the lung base as high as the Thoracic 12 vertebrae, 9.5 cm right lung laceration, right hemothorax, and emphysema subcutis on the right inferior side of hemithorax. The patient planned surgery to extract the corpus allienum through a lateral extra cavitary approach to expose the lungs at the level of the Th10-12 vertebrae. The lateral extra cavitary approach can be an alternative, less invasive method to extract foreign body lung base in front of vertebrae thoracic region.

EFEKTIVITAS SATUAN TUGAS PENCEGAHAN DAN PENANGANAN KEKERASAN SEKSUAL UNIVERSITAS DIPONEGORO DALAM PERSPEKTIF TEORI SISTEM HUKUM LAWRENCE M. FRIEDMAN Rofifah, Salma Putri; Purwanti, Ani; Indreswari, Tri Laksmi
Diponegoro Law Journal Vol 13, No 4 (2024): Volume 13 Nomor 4, Tahun 2024
Publisher : Program Studi S1 Ilmu Hukum, Fakultas Hukum, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dlj.2024.45563

Kekerasan seksual di perguruan tinggi dapat berimplikasi pada terhambatnya akses peserta didik terhadap pendidikan yang nyaman dan tidak diskriminatif. Permendikbudristek No. 30 Tahun 2021 memandatkan pembentukan Satuan Tugas Pencegahan dan Penanganan Kekerasan Seksual (Satgas PPKS) bagi masing-masing perguruan tinggi. Universitas Diponegoro membentuk Satgas PPKS sebagai upaya strategis mendorong terciptanya lingkungan Universitas Diponegoro yang aman dari kekerasan seksual. Penelitian ini menjabarkan mengenai regulasi perlindungan hukum nasional terhadap kekerasan seksual, implementasi pembentukan serta pelaksanaan tugas dan wewenang Satgas PPKS Undip, serta menganalisis efektivitas kinerja Satgas PPKS Undip dalam tinjauan Teori Sistem Hukum Lawrence M. Friedman dengan menggunakan metode pendekatan yuridis-sosiologis. Berdasarkan hasil penelitian, ditemukan bahwa masih diperlukan evaluasi dan perbaikan untuk mendorong kinerja Satgas PPKS Undip yang efektif dan sesuai dengan ketentuan Permendikbudristek No. 30 Tahun 2021 seperti perbaikan landasan hukum Satgas PPKS Undip, optimalisasi kinerja Satgas PPKS Undip dan penyediaan fasilitas dan sarana-prasarana pendukung, serta peningkatan pengetahuan masyarakat.

Peningkatan Risiko Infeksi Genital pada Pengguna SGLT-2 Inhibitor Purnomo, Farah Fadhila Nasywa; Hairrudin, Hairrudin; Indreswari, Laksmi
Jurnal Pharmascience Vol 11, No 2 (2024): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v11i2.18846

SGLT-2 inhibitor merupakan salah satu terapi farmakologis oral yang diberikan pada pasien Diabetes Mellitus tipe 2. Risiko infeksi genitourinari pada pengguna SGLT-2 inhibitor masih belum jelas. Penelitian ini bertujuan untuk menganalisis risiko infeksi saluran genitourinari pada pasien diabetes melitus tipe 2 yang diterapi menggunakan sodium-glucose co-transporter-2 (SGLT-2) inhibitor. Metode penulisan menggunakan desain penelitian tinjauan sistematis (Systematic Review). Pencarian jurnal dilakukan pada basis data Pubmed Central, Science Direct dan Google Scholar (pencarian hingga 17 Mei 2023) lalu diseleksi menggunakan Flowchart PRISMA. Studi yang diseleksi menggunakan design studi cohort/observational studies yang dibandingkan dengan terapi nonSGLT-2 inhibitor. Analisis data menggunakan metaanalisis. Hasil penelitian didapatkan 10 jurnal yang ditinjau secara sistematis tetapi hanya 6 jurnal yang dipat di metaanalisis dikarenakan heterogenitas yang tinggi. Empat jurnal dengan outcome infeksi saluran kemih yang dimetaanalisis menunjukkan risiko tidak signifkan (RR 0,98 95%CI 0,85-1,14; p= 0,80; I2=57%). Dua jurnal dengan outcome infeksi genital yang dimetaanalisis menghasilkan risiko 2,3 kali lipat lebih tinggi dibanding non-SGLT-2 inhibitor(RR 2,32 95%CI 2,04-2,64; p<0,00001; I2=36%). Kesimpulannya terjadi peningkatan risiko infeksi genital pada pasien diabetes melitus tipe 2 yang diterapi menggunakan sodium-glucose co-transporter-2 (SGLT-2) inhibitor yang signifikan sedangkan peningkatan risiko infeksi saluran kemih tidak signifikan. Kata Kunci: Diabetes Melitus Tipe 2, Infeksi Genital, Infeksi Saluran Kemih, Antidiabetes, SGLT-2 Inhibitor SGLT-2 inhibitors are an oral pharmacological therapy given to patients with type 2 diabetes mellitus. The risk of genitourinary infections in SGLT-2 inhibitor users is still unclear. This study aims to analyze the risk of genitourinary tract infections in patients with type 2 diabetes mellitus treated with sodium-glucose co-transporter-2 (SGLT-2) inhibitors. The method uses a systematic review research design.. Journal searches were carried out on the Pubmed Central, Science Direct, and Google Scholar databases (search until 17 May 2023) and then selected using the PRISMA Flowchart. The selected studies used a cohort/observational study design compared to nonSGLT-2 inhibitor therapy. Data analysis using meta-analysis. The results showed that 10 journals were reviewed systematically, but only 6 journals were included in the meta-analysis due to high heterogeneity. Four journals with urinary tract infection outcomes that were meta-analyzed showed an insignificant risk (RR 0.98 95%CI 0.85-1.14; p= 0.80; I2=57%). Two journals with meta-analyzed outcomes of genital infections resulted in a 2.3-fold higher risk compared to non-SGLT-2 inhibitors (RR 2.32 95%CI 2.04-2.64; p<0.00001; I2=36%). In conclusion, there was a significant increase in risk for genital infections while it was not significant for urinary tract infections.

ANALYSIS OF RAT PLATELET COUNT AFTER ELECTRICAL EXPOSURE IN ACUTE AND SUBACUTE PHASE OF BURN INJURY F P H, Fransiska Nooril; Elfiah, Ulfa; Indreswari, Laksmi; Wisudanti, Desie Dwi
Jurnal Rekonstruksi dan Estetik Vol. 4 No. 1 (2019): Jurnal Rekonstruksi dan Estetik, June 2019
Publisher : Universitas Airlangga

Highlights: In the acute phase of electric burn injury, there was a significant change in platelet count. Contrarily, no significant change in platelet count was observed during the subacute phase of electric burn injury. Abstract: Introduction: Electrical burns are one of the causes of important health burdens throughout the world with incidences varying between 4–18% of all burns. In electrical burns, blood vessels are the heavily damaged tissue characterized by endothelial erosion, followed by adhesion and aggregation of platelets to form a hemostatic plug. The screening test for assessing the formation of a hemostatic plug is platelet count. Platelet count monitoring is very important during the resuscitation phase and treatment periods in severe burns, namely in acute and subacute phases of burns. The purpose of this study is to determine and analyze the changes in the platelet count of rats after electrical exposure in the acute and subacute phases of burns. Methods: This is a quasi-experimental study in vivo with post-test-only group design. The control group in this study was not given electrical exposure and the rat's blood was taken directly after the adaptation process. In the other five groups, P1, P2, P3, P4, and P5 were exposed to 140 V for 17 seconds, then their blood was taken for platelet counts on days 0, 3, 7, 10, and 14 post-exposure. Results : The result of this study based on a Post Hoc LSD test showed that there was a change of platelet number after exposure in the acute phase of burn injury and there was no change of platelet number after exposure in the burning subacute phase. Conclusions: Platelet count difference in acute phase of electric burn injury and no difference in platelet count difference in subacute phase of electric burn injury.

Good Knowledge of COVID-19 Increased Preventive Behavior on Last Year Undergraduate Medical Students at University of Jember, East Java, Indonesia Safitri, Raghda Gita; Marchianti, Ancah Caesarina Novi; Indreswari, Laksmi
Journal of Health Promotion and Behavior Vol. 6 No. 2 (2021)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Background: Indonesia is in first place in ASEAN regarding the high number of confirmed cases and deaths of Covid-19 on November 9, 2020. This can be caused by a lack of preventive behavior related to Covid-19, one of which is influenced by knowledge. The purpose of this study was to determine the relationship between knowledge level of Covid-19 and Covid-19 preventive behavior in last year undergraduate medical students at University of Jember.Subjects and Method: A cross sectional study was conducted online through a questionnaire that will be distributed using Google form in May 2021. A total of 121 last year undergraduate medical students at University of Jember were enrolled using a total sampling technique. The dependent variable is level of knowledge related to Covid-19 and the independent variable is Covid-19 preventive behavior. The data obtained through Google form will be analyzed using the SPSS version 26.0 application and using the Spearman Rho Correlation method. Results: Based on univariate analytic, 97.5% students have a good knowledge and 90.9% students perform high preventive behavior of Covid-19. Bivariate analytic by testing correlation ¬between one’s knowledge of Covid-19 and the preventive behavior obtained p <0.001 correlation coefficient of 0.504.Conclusion: The good knowledge of Covid-19 increased preventive behavior on last year undergraduate medical students at University of Jember.Keywords: Physical distancing, Covid-19, online questionnaire.Correspondence: Ancah Caesarina Novi Marchianti. Faculty of Medicine, University of Jember. Jl. Kalimantan Tegalboto 37, Jember, East Java, Indonesia. Email: ancah@unej.ac.id. Mobile Phone:+62331-337877.Journal of Health Promotion and Behavior (2021), 06(02): 97-103https://doi.org/10.26911/thejhpb.2021.06.02.02

ANALISIS RISIKO PENGEMBANGAN WISATA KULINER TIRTA AGUNG DI KABUPATEN BONDOWOSO Amilia, Winda; Rusdianto, Andrew Setiawan; Suryaningrat, Ida Bagus; Prasetya, Rendra Chriestedy; Fatimatuzzahro, Nadie; Sampurna, Hadi; Rokhani, Rokhani; Indreswari, Laksmi; Pranata, Dadin Gilang; Baladraf, Thabed Tholib
Jurnal Industri Parawisata Vol 6 No 1 (2023): Jurnal Industri Pariwisata JULY 2023
Publisher : Universitas Sahid

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36441/pariwisata.v6i1.1219

Pandemi Covid-19 melumpuhkan berbagai sektor salah satunya pariwisata. Hal ini berdampak terhadap mobilitas masyarakat sehingga banyak ditemui wisata yang tutup, seiring membaiknya keadaan saat ini mulai banyak ditemui wisata yang mulai dibuka kembali, salah satu tempat wisata yang dibuka adalah wisata kuliner Tirta Agung. Wisata kuliner Tirta Agung merupakan kawasan rekreasi yang terdiri dari kolam renang, wisata kuliner, dan pemandangan. Wisata kuliner Tirta Agung kawasan rekreasi terbaik yang dimiliki Kabupaten Bondowoso. Tujuan penelitian ini adalah untuk memberikan rekomendasi kepada pengelola kawasan Wisata Tirta Agung terkait dengan kesehatan dan keselamatan wisatawan. Penelitian dimulai dengan pengumpulan data primer melalui wawancara wisatawan menggunakan kuesioner dan data sekunder. Selanjutnya dilakukan pengolahan data menggunakan metode House of Risk (HOR) yang terdiri dari dua fase. Fase pertama dilakukan identifikasi sumber dan kejadian risiko serta dilakukan perhitungan pada nilai Risk Priority Number dan Risk Potential Number. Data yang sudah didapatkan lalu dianalisis pada HOR fase kedua sehingga dapat tercipta strategi mitigasi risiko bagi pelaku wisata. Hasil menunjukkan terdapat 7 agen risiko yang diprioritaskan yaitu tidak adanya pemeriksaan awal, luas lahan yang sempit, jam operasional yang panjang, meja dan kursi tidak steril, tidak tersedianya mesin EDC, rendahnya kesadaran karyawan dan rendahnya kesadaran pengunjung. Dari agen risiko yang ditemukan, didapatkan 4 strategi penanganan antara lain pengecekan terkait kondisi kesehatan pengunjung, perawatan aksesoris, penyampaian aturan yang berlaku kepada pengunjung, dan mempertegas kebijakan yang ada terhadap setiap pengunjung dan karyawan wisata.

Cardiac Tamponade in a Chronic Renal Failure Patient with Suspicion of Dialysis Pericarditis: A Case Report Wulandari, Pipiet; Suryono, Suryono; Prasetyo, Aris; Firdaus, Jauhar; Sofiana, Kristianingrum Dian; Indreswari, Laksmi; Handoko, Adelia; Setia, Bagus
International Journal of Health and Information System Vol. 2 No. 1 (2024): May
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/ijhis.v2i1.39

Pericardial effusion is a condition characterized by fluid accumulation in the pericardial cavity. This fluid accumulation can cause disturbances in cardiac contractility, affecting hemodynamic stability. Fluid accumulation is caused by several factors, ranging from the amount of fluid, the speed of fluid accumulation, and the ability of the pericardium to accommodate fluid. One of the causes of pericardial effusion is pericarditis. Pericarditis can be caused by infection and non-infection, such as in patients with chronic renal failure with an incidence of 2-21%, which can lead to cardiac tamponade. In this study, a 46-year-old male patient who came to the emergency room of Dr. Soebandi Hospital, Jember with complaints of shortness of breath in the last 2 months. The patient also complained of heartburn. The patient had a history of chronic renal failure and routinely performed hemodialysis. On examination of vital signs, thoracic photographs, and echocardiography, a picture of cardiac tamponade was found. Cardiac tamponade can occur in patients with chronic renal failure. This is due to the condition of uremia which causes pericarditis. Inflammation of the pericardium causes blood that is intravascular to enter the pericardial cavity, causing fluid accumulation there. If not treated immediately, it can lead to cardiac tamponade which endangers the patient's life.

Konsumsi Ikan Asin Meningkatkan Risiko Kanker Nasofaring: Tinjauan Sistematik dan Meta-analisis MUNAWIR, AL; Dika Pangestu, Yusufa; Indreswari, Laksmi
Jurnal Otorinolaringologi Kepala dan Leher Indonesia Vol. 2 No. 1 (2023)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jokli.v2i1.46

Latar Belakang: Kanker nasofaring atau sering disebut sebagai KNF adalah penyakit keganasan sel skuamosa pada lapisan epitel nasofaring. Konsumsi makanan diawetkan menyumbang persentase tertinggi penyebab KNF sebesar 35,5%, salah satu makanan diawetkan adalah ikan asin. Terdapat perbedaan pendapat di antara studi-studi yang ada mengenai pengaruh konsumsi ikan asin terhadap risiko kanker nasofaring. Beberapa studi menunjukkan adanya peningkatan risiko, sementara studi lainnya menyatakan bahwa konsumsi ikan asin tidak memiliki pengaruh signifikan terhadap kejadian kanker nasofaring. Tujuan: membuktikan konsumsi ikan asin meningkatkan risiko kanker nasofaring. Metode: Tinjauan sistematik dan meta-analisis. Hasil; Dari enam studi, lima studi menunjukkan hasil yang signifikan dan satu studi menunjukkan hasil yang tidak signifikan. Hasil meta-analisis didapatkan nilai p<0,00001 dan crude OR sebesar 1,65. Kesimpulan: Konsumsi ikan asin lebih dari tiga kali dalam satu bulan dapat meningkatkan risiko kanker nasofaring sebesar 1,65 kali. Background: Nasopharyngeal cancer, often referred to as NPC, is a disease of squamous cells on the epithelial layer of the nasopharynx. Consumption of foods contributed to the highest percentage of KNF causes at 35.5%, one of the foods consumed was salted fish. There are differences of opinion between existing studies on the influence of salted fish consumption on the risk of nasopharyngeal cancer. Some studies indicate an increased risk, while other studies state that salted fishing has no significant influence on the incidence of nasopharynx cancer. Objective: Prove that the consumption of salted fish increases the risk of nasopharyngeal cancer. Methods: Systematic review and meta-analysis. Results; Out of six studies, five studies showed significant results and one study showed insignificant results. The meta-analysis resulted in a p<0,00001 and a crude OR of 1.65. Conclusion: Consumption of salted fish more than three times in a month can increase the risk of nasopharyngeal cancer by 1.65 times.

Co-Authors Adinningtyas Intansari Adji, Novan Krisno Ahmad Baihaqi Al Munawir Alif Mardijana Ancah Caesarina Novi Marchianti Ani Purwanti Anisa Rizca Putri Aris Prasetyo Aris Prasetyo Bagus Hermansyah Baladraf, Thabed Tholib BJ Azmy As'ady Cholis Abrori, Cholis Desie Dwi Wisudanti Dicky Setiawan Dika Pangestu, Yusufa Dini Agustina Dwita Aryadina Rachmawati El Milla, Kardiana Izza ENNY SUSWATI F P H, Fransiska Nooril Habibi, Ali Hairrudin Hairrudin Handoko, Adelia Ida Bagus Suryaningrat Jauhar Firdaus Kristianningrum Dian Sofiana Lathifa Rusyda Gani Laylatul Fitriah Mukarromah Luh Putu Ratna Sundari M.S. Irham Rozaq Murniati, Yunita Nadie Fatimatuzzahro Nugraha, Muhammad Yuda Pipiet Wulandari Pralampita, Pulong Wijang Pranata, Dadin Gilang Prasetyo, Aris Purnomo, Farah Fadhila Nasywa Putri, Komang Yunita Wiryaning Rahmad Adi Prasetyo Rena Normasari Rendra Chriestedy Prasetya Rofifah, Salma Putri Rokhani Rokhani Rozaq, M.S. Irham Rusdianto, Andrew Setiawan Safitri, Raghda Gita Sampurna, Hadi septa surya wahyudi, septa surya Setia, Bagus Sofiana, Kristianingrum Dian Supangat Supangat Supangat Supangat Suryono Suryono Tristianti, Farmitalia Nisa Ulfa Elfiah Winda Amilia Wiwien Sugih Utami Yunita Armiyanti Yunita Dewi Anggraeni

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