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All Journal Diponegoro Law Journal Damianus Journal of Medicine Journal of Agromedicine and Medical Sciences Syifa' MEDIKA: Jurnal Kedokteran dan Kesehatan Buletin Poltanesa Jurnal Industri Pariwisata Solo Journal of Anesthesi, Pain and Critical Care Jurnal Rekonstruksi dan Estetik International Journal on Health and Medical Sciences Jember Medical Journal (JMJ) International Journal of Health and Information System (IJHIS) Jurnal Otorinolaringologi Kepala dan Leher Indonesia (JOKLI) Folia Medica Indonesiana Jurnal Veteriner

Laksmi Indreswari

Anatomi, Universitas Jember

Author-ID : 3307493

Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Library & Information Science Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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Sinonasal Bone Destruction caused by Frontal Meningioma Invasion related with Respiratory Tract Infection Incident: A Case Report Adji, Novan Krisno; Putri, Komang Yunita Wiryaning; Indreswari, Laksmi; Nugraha, Muhammad Yuda
Jember Medical Journal Vol. 1 No. 1 (2022)
Publisher : Faculty of Medicine, University of Jember

Meningioma is uncommonly found in extracranial. Extracranial meningioma can be extension from primary intracranial tumors that accompany osteolytic changes in the skull or causes bone destruction. In this article, we report about intracranial meningioma in the frontal region that extend to the sinonasal bone causes bone destruction and being predisposing factor for respiratory tract infection. A 47-years old female brought to the emergency department due to dyspnea and fever since a week ago and there was found a lump in the frontal region. During the surgical procedure, there was invasion of tumor and caused sinonasal bone destruction. The endotracheal tube (ETT) can be seen from the surgical field. In this case the patient was threated pneumonia infection, it can be related as complication of sinonasal bone destruction that caused by invasion of meningioma to extracranial manifestation. The clinical important that must be informed to the patient the possibility of recurrent respiratory tract infection incidents.

Physical Water Quality and Intestinal Protozoa Contamination on Household Water in Ajung District, Jember Regency Dicky Setiawan; Wiwien Sugih Utami; Laksmi Indreswari; Yunita Armiyanti; Bagus Hermansyah
Jember Medical Journal Vol. 1 No. 1 (2022)
Publisher : Faculty of Medicine, University of Jember

Intestinal protozoa infections are still a major health problem in worldwide. The prevalence of intestinal protozoa infections are relatively high in countries facing lack of safe drinking water and lack of suitable sanitation facilities. Lack of sanitation facilities, open defecation, and contamination of environmental feces can make water quality worse, both in terms of physically, chemically, and biologically. Physical water quality is poor when the household water used daily does not meet the standard parameters of the physical water quality standard. The purpose of this study was to determine the relationship between physical water quality and intestinal protozoa contamination in household water in Ajung District, Jember Regency. This type of research is an observational analytic study with a cross sectional research design. The research method used is the correlation method, namely the relationship between physical water quality and intestinal protozoa contamination in household water. The population in this study is household water in Ajung District, Jember Regency. Data analysis consisted of univariate analysis to see the distribution and percentage of temperature, total dissolves solid, color, odor, and intestinal protozoa contamination in household water, and then bivariate analysis using the Chi-square test to analyze physical water quality and intestinal protozoa contamination. The conclusion is there is a relationship between physical water quality and intestinal protozoa contamination in household water.

Extraction of Air Gun Pellet in Lung Base Thoracic Vertebrae Region with Lateral Extracavitary Approach: A Case Report Adji, Novan Krisno; Putri, Komang Yunita Wiryaning; Indreswari, Laksmi; Nugraha, Muhammad Yuda; Habibi, Ali
Jember Medical Journal Vol. 2 No. 2 (2023)
Publisher : Faculty of Medicine, University of Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/jembermedicaljournal.v2i2.452

Thoracic gunshot injuries are associated with significant morbidity and mortality, but fatal accidents from air guns are rare. Surgery in this area is challenging, especially if the gun pellet penetrates the visceral organ like the lung. In this case, we present a case of an 18-year-old male who came to the emergency department with an air gunshot (pellet) that penetrated the chest and settled in the lung base. After being shot by an air gun, the patient came with pain in the right back and weakness in both lower extremities. Based on the radiological examination, metallic corpus allienum measuring ± 0.8 x 0.7 cm has shown at the lung base as high as the Thoracic 12 vertebrae, 9.5 cm right lung laceration, right hemothorax, and emphysema subcutis on the right inferior side of hemithorax. The patient planned surgery to extract the corpus allienum through a lateral extra cavitary approach to expose the lungs at the level of the Th10-12 vertebrae. The lateral extra cavitary approach can be an alternative, less invasive method to extract foreign body lung base in front of vertebrae thoracic region.

EFEKTIVITAS SATUAN TUGAS PENCEGAHAN DAN PENANGANAN KEKERASAN SEKSUAL UNIVERSITAS DIPONEGORO DALAM PERSPEKTIF TEORI SISTEM HUKUM LAWRENCE M. FRIEDMAN Rofifah, Salma Putri; Purwanti, Ani; Indreswari, Tri Laksmi
Diponegoro Law Journal Vol 13, No 4 (2024): Volume 13 Nomor 4, Tahun 2024
Publisher : Program Studi S1 Ilmu Hukum, Fakultas Hukum, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dlj.2024.45563

Kekerasan seksual di perguruan tinggi dapat berimplikasi pada terhambatnya akses peserta didik terhadap pendidikan yang nyaman dan tidak diskriminatif. Permendikbudristek No. 30 Tahun 2021 memandatkan pembentukan Satuan Tugas Pencegahan dan Penanganan Kekerasan Seksual (Satgas PPKS) bagi masing-masing perguruan tinggi. Universitas Diponegoro membentuk Satgas PPKS sebagai upaya strategis mendorong terciptanya lingkungan Universitas Diponegoro yang aman dari kekerasan seksual. Penelitian ini menjabarkan mengenai regulasi perlindungan hukum nasional terhadap kekerasan seksual, implementasi pembentukan serta pelaksanaan tugas dan wewenang Satgas PPKS Undip, serta menganalisis efektivitas kinerja Satgas PPKS Undip dalam tinjauan Teori Sistem Hukum Lawrence M. Friedman dengan menggunakan metode pendekatan yuridis-sosiologis. Berdasarkan hasil penelitian, ditemukan bahwa masih diperlukan evaluasi dan perbaikan untuk mendorong kinerja Satgas PPKS Undip yang efektif dan sesuai dengan ketentuan Permendikbudristek No. 30 Tahun 2021 seperti perbaikan landasan hukum Satgas PPKS Undip, optimalisasi kinerja Satgas PPKS Undip dan penyediaan fasilitas dan sarana-prasarana pendukung, serta peningkatan pengetahuan masyarakat.

ANALYSIS OF RAT PLATELET COUNT AFTER ELECTRICAL EXPOSURE IN ACUTE AND SUBACUTE PHASE OF BURN INJURY F P H, Fransiska Nooril; Elfiah, Ulfa; Indreswari, Laksmi; Wisudanti, Desie Dwi
Jurnal Rekonstruksi dan Estetik Vol. 4 No. 1 (2019): Jurnal Rekonstruksi dan Estetik, June 2019
Publisher : Universitas Airlangga

Highlights: In the acute phase of electric burn injury, there was a significant change in platelet count. Contrarily, no significant change in platelet count was observed during the subacute phase of electric burn injury. Abstract: Introduction: Electrical burns are one of the causes of important health burdens throughout the world with incidences varying between 4–18% of all burns. In electrical burns, blood vessels are the heavily damaged tissue characterized by endothelial erosion, followed by adhesion and aggregation of platelets to form a hemostatic plug. The screening test for assessing the formation of a hemostatic plug is platelet count. Platelet count monitoring is very important during the resuscitation phase and treatment periods in severe burns, namely in acute and subacute phases of burns. The purpose of this study is to determine and analyze the changes in the platelet count of rats after electrical exposure in the acute and subacute phases of burns. Methods: This is a quasi-experimental study in vivo with post-test-only group design. The control group in this study was not given electrical exposure and the rat's blood was taken directly after the adaptation process. In the other five groups, P1, P2, P3, P4, and P5 were exposed to 140 V for 17 seconds, then their blood was taken for platelet counts on days 0, 3, 7, 10, and 14 post-exposure. Results : The result of this study based on a Post Hoc LSD test showed that there was a change of platelet number after exposure in the acute phase of burn injury and there was no change of platelet number after exposure in the burning subacute phase. Conclusions: Platelet count difference in acute phase of electric burn injury and no difference in platelet count difference in subacute phase of electric burn injury.

ANALISIS RISIKO PENGEMBANGAN WISATA KULINER TIRTA AGUNG DI KABUPATEN BONDOWOSO Amilia, Winda; Rusdianto, Andrew Setiawan; Suryaningrat, Ida Bagus; Prasetya, Rendra Chriestedy; Fatimatuzzahro, Nadie; Sampurna, Hadi; Rokhani, Rokhani; Indreswari, Laksmi; Pranata, Dadin Gilang; Baladraf, Thabed Tholib
Jurnal Industri Parawisata Vol 6 No 1 (2023): Jurnal Industri Pariwisata JULY 2023
Publisher : Universitas Sahid

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36441/pariwisata.v6i1.1219

Pandemi Covid-19 melumpuhkan berbagai sektor salah satunya pariwisata. Hal ini berdampak terhadap mobilitas masyarakat sehingga banyak ditemui wisata yang tutup, seiring membaiknya keadaan saat ini mulai banyak ditemui wisata yang mulai dibuka kembali, salah satu tempat wisata yang dibuka adalah wisata kuliner Tirta Agung. Wisata kuliner Tirta Agung merupakan kawasan rekreasi yang terdiri dari kolam renang, wisata kuliner, dan pemandangan. Wisata kuliner Tirta Agung kawasan rekreasi terbaik yang dimiliki Kabupaten Bondowoso. Tujuan penelitian ini adalah untuk memberikan rekomendasi kepada pengelola kawasan Wisata Tirta Agung terkait dengan kesehatan dan keselamatan wisatawan. Penelitian dimulai dengan pengumpulan data primer melalui wawancara wisatawan menggunakan kuesioner dan data sekunder. Selanjutnya dilakukan pengolahan data menggunakan metode House of Risk (HOR) yang terdiri dari dua fase. Fase pertama dilakukan identifikasi sumber dan kejadian risiko serta dilakukan perhitungan pada nilai Risk Priority Number dan Risk Potential Number. Data yang sudah didapatkan lalu dianalisis pada HOR fase kedua sehingga dapat tercipta strategi mitigasi risiko bagi pelaku wisata. Hasil menunjukkan terdapat 7 agen risiko yang diprioritaskan yaitu tidak adanya pemeriksaan awal, luas lahan yang sempit, jam operasional yang panjang, meja dan kursi tidak steril, tidak tersedianya mesin EDC, rendahnya kesadaran karyawan dan rendahnya kesadaran pengunjung. Dari agen risiko yang ditemukan, didapatkan 4 strategi penanganan antara lain pengecekan terkait kondisi kesehatan pengunjung, perawatan aksesoris, penyampaian aturan yang berlaku kepada pengunjung, dan mempertegas kebijakan yang ada terhadap setiap pengunjung dan karyawan wisata.

Cardiac Tamponade in a Chronic Renal Failure Patient with Suspicion of Dialysis Pericarditis: A Case Report Wulandari, Pipiet; Suryono, Suryono; Prasetyo, Aris; Firdaus, Jauhar; Sofiana, Kristianingrum Dian; Indreswari, Laksmi; Handoko, Adelia; Setia, Bagus
International Journal of Health and Information System Vol. 2 No. 1 (2024): May
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/ijhis.v2i1.39

Pericardial effusion is a condition characterized by fluid accumulation in the pericardial cavity. This fluid accumulation can cause disturbances in cardiac contractility, affecting hemodynamic stability. Fluid accumulation is caused by several factors, ranging from the amount of fluid, the speed of fluid accumulation, and the ability of the pericardium to accommodate fluid. One of the causes of pericardial effusion is pericarditis. Pericarditis can be caused by infection and non-infection, such as in patients with chronic renal failure with an incidence of 2-21%, which can lead to cardiac tamponade. In this study, a 46-year-old male patient who came to the emergency room of Dr. Soebandi Hospital, Jember with complaints of shortness of breath in the last 2 months. The patient also complained of heartburn. The patient had a history of chronic renal failure and routinely performed hemodialysis. On examination of vital signs, thoracic photographs, and echocardiography, a picture of cardiac tamponade was found. Cardiac tamponade can occur in patients with chronic renal failure. This is due to the condition of uremia which causes pericarditis. Inflammation of the pericardium causes blood that is intravascular to enter the pericardial cavity, causing fluid accumulation there. If not treated immediately, it can lead to cardiac tamponade which endangers the patient's life.

Konsumsi Ikan Asin Meningkatkan Risiko Kanker Nasofaring: Tinjauan Sistematik dan Meta-analisis MUNAWIR, AL; Dika Pangestu, Yusufa; Indreswari, Laksmi
Jurnal Otorinolaringologi Kepala dan Leher Indonesia Vol. 2 No. 1 (2023)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jokli.v2i1.46

Latar Belakang: Kanker nasofaring atau sering disebut sebagai KNF adalah penyakit keganasan sel skuamosa pada lapisan epitel nasofaring. Konsumsi makanan diawetkan menyumbang persentase tertinggi penyebab KNF sebesar 35,5%, salah satu makanan diawetkan adalah ikan asin. Terdapat perbedaan pendapat di antara studi-studi yang ada mengenai pengaruh konsumsi ikan asin terhadap risiko kanker nasofaring. Beberapa studi menunjukkan adanya peningkatan risiko, sementara studi lainnya menyatakan bahwa konsumsi ikan asin tidak memiliki pengaruh signifikan terhadap kejadian kanker nasofaring. Tujuan: membuktikan konsumsi ikan asin meningkatkan risiko kanker nasofaring. Metode: Tinjauan sistematik dan meta-analisis. Hasil; Dari enam studi, lima studi menunjukkan hasil yang signifikan dan satu studi menunjukkan hasil yang tidak signifikan. Hasil meta-analisis didapatkan nilai p<0,00001 dan crude OR sebesar 1,65. Kesimpulan: Konsumsi ikan asin lebih dari tiga kali dalam satu bulan dapat meningkatkan risiko kanker nasofaring sebesar 1,65 kali. Background: Nasopharyngeal cancer, often referred to as NPC, is a disease of squamous cells on the epithelial layer of the nasopharynx. Consumption of foods contributed to the highest percentage of KNF causes at 35.5%, one of the foods consumed was salted fish. There are differences of opinion between existing studies on the influence of salted fish consumption on the risk of nasopharyngeal cancer. Some studies indicate an increased risk, while other studies state that salted fishing has no significant influence on the incidence of nasopharynx cancer. Objective: Prove that the consumption of salted fish increases the risk of nasopharyngeal cancer. Methods: Systematic review and meta-analysis. Results; Out of six studies, five studies showed significant results and one study showed insignificant results. The meta-analysis resulted in a p<0,00001 and a crude OR of 1.65. Conclusion: Consumption of salted fish more than three times in a month can increase the risk of nasopharyngeal cancer by 1.65 times.

Analisis Penggunaan Jumlah Bahan Aktif Pestisida dan Banyaknya Keluhan Masalah Kesehatan Pada Petani di Wilayah Agroindustri Jember Sofiana, Kristianningrum Dian; Indreswari, Laksmi; Firdaus, Jauhar; Prasetyo, Aris; Pralampita, Pulong wijang; Supangat, Supangat
Poltanesa Vol 23 No 1 (2022): Juni 2022
Publisher : P3KM Politeknik Pertanian Negeri Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51967/tanesa.v23i1.1209

Pestisida dapat menyebabkan masalah kesehatan baik akut ataupun kronik. Latar belakang dari penelitian ini adalah Penggunaan pestisida di kawasan agroindustri Jember yang tidak dapat dihindari.. Paparan pestisida pada petani Jember, baik paparan langsung ataupun tidak langsung, diduga menjadi salah satu penyebab munculnya masalah kesehatan.. Keterkaitan antar penggunaan bahan aktif pestisida dan masalah kesehatan pada petani di wilayah agroindustri jember perlu diteliti. Penelitian ini bertujuan untuk menganalisis penggunaan jumlah bahan aktif pestisida dengan banyaknya masalah kesehatan pada petani di wilayah Agroindustri Jember. Penelitian ini menggunakan metode deskriptif observational dengan pendekatan cross-sectional. Populasi yang diambil adalah petani yang berada di kabupaten jember yang diwakili oleh 11 kecamatan. Besar sampel berjumlah 84 orang yang diambil dengan accidental sampling. Variabel yang diambil adalah jenis pestisida, jumlah bahan aktif yang dipakai, keluhan masalah kesehatan, Analisis menggunakan analisis unvaried dan bivariate menggunakan Chi square tes dengan p <0,05. Penggunaan bahan aktif yang digunakan selama penyemprotan mayoritas 1 bahan aktif 51,19% .Keluhan masalah kesehatan sebesar 52,38% dengan keluhan terbanyak adalah pusing sebesar 29,76%.Hasil Analisis jumlah bahan aktif saat penyemprotan dengan banyaknya keluhan kesehatan dengan menggunakan Chi Square tes, p= 0,009 dengan nilai p<0,05. Dari penelitian ini didapatkan ada hubungan penggunaan bahan aktif residu pestisida dengan keluhan masalah kesehatan pada petani di Jember. Petani yang terpapar kebanyakan tidak merasakan keluhan kesehatan.

Combination Therapy for Cryptosporidiosis in Immunocompromised Patients: A Systematic Review Utami, Wiwien Sugih; Rozaq, M.S. Irham; Indreswari, Laksmi; Abrori, Cholis; Hermansyah, Bagus
Folia Medica Indonesiana Vol. 60, No. 4
Publisher : Folia Medica Indonesiana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Cryptosporidium sp. is a gastroenteritis-causing pathogen that may increase mortality and morbidity in immunocompromised patients. Diarrhea is a common problem among acquired immunodeficiency syndrome (AIDS) patients, with 30–60% of patients in developed countries and 90% in developing countries affected. The prevalence of cryptosporidiosis is 3–5% of the global population, with 14.42% of those affected being immunocompromised. There is currently no vaccine available to prevent cryptosporidiosis, while nitazoxanide monotherapy is ineffective in eradicating the organism in immunocompromised hosts and malnourished children. This study aimed to determine the most effective combination therapy for cryptosporidiosis in immunocompromised patients. This study used a systematic review design and implemented eligibility criteria for the literature search across PubMed, ScienceDirect, Epistemonikos, Google Scholar, Nature, Springer, and John Wiley databases. The search utilized specific keywords and Boolean operators, i.e., “Cryptosporidium,” OR “cryptosporidiosis,” AND “combination therapy,” OR “combination treatment,” AND “immunocompromised.” Two cohort studies and two case reports were selected, three of which used a nitazoxanide and azithromycin combination as the intervention, whereas only one cohort study used a nitazoxanide and fluoroquinolone combination. The studies comprised 54 samples from post-kidney transplantation patients and one sample from an acute lymphoblastic leukemia (ALL) patient. The nitazoxanide and fluoroquinolone combination showed superior outcomes than the nitazoxanide and azithromycin combination. The stool clearance was significantly lower with nitazoxanide monotherapy than the nitazoxanide and fluoroquinolone combination (OR=0.65, 95% CI=0.34–0.92, p=0.01). However, it was non-significantly lower with the nitazoxanide and azithromycin combination compared to monotherapy (OR=0.27, 95% CI=0.01–5.77, p=0.24). Nitazoxanide monotherapy exerted a significantly lower effect than the nitazoxanide and fluoroquinolone combination in stopping diarrhea symptoms (OR=0.45, 95% CI=0.21–0.81, p=0.004). In conclusion, a combination therapy using nitazoxanide and fluoroquinolone for cryptosporidiosis in immunocompromised patients offers more favorable outcomes compared to monotherapy, particularly in stopping diarrhea and enhancing stool clearance.

Co-Authors Adinningtyas Intansari Adji, Novan Krisno Ahmad Baihaqi Al Munawir Alif Mardijana Ancah Caesarina Novi Marchianti Ani Purwanti Anisa Rizca Putri Aris Prasetyo Aris Prasetyo Armianti, Yunita Bagus Hermansyah Baladraf, Thabed Tholib BJ Azmy As'ady Cholis Abrori, Cholis Desie Dwi Wisudanti Dicky Setiawan Dika Pangestu, Yusufa Dini Agustina Dwita Aryadina Rachmawati El Milla, Kardiana Izza ENNY SUSWATI Erisadana, Rifaldy Nabiel F P H, Fransiska Nooril Furqon, Achmad Nazalal Habibi, Ali Hairrudin Hairrudin Handoko, Adelia Ida Bagus Suryaningrat Jauhar Firdaus Kristianningrum Dian Sofiana Lathifa Rusyda Gani Laylatul Fitriah Mukarromah Luh Putu Ratna Sundari M.S. Irham Rozaq Murniati, Yunita Nadie Fatimatuzzahro Nugraha, Muhammad Yuda Pipiet Wulandari Pralampita, Pulong Wijang Pranata, Dadin Gilang Prasetyo, Aris Purnomo, Farah Fadhila Nasywa Putri, Komang Yunita Wiryaning Rahmad Adi Prasetyo Rena Normasari Rendra Chriestedy Prasetya Rofifah, Salma Putri Rokhani Rokhani Rozaq, M.S. Irham Rusdianto, Andrew Setiawan Safitri, Raghda Gita Sampurna, Hadi septa surya wahyudi, septa surya Setia, Bagus Sofiana, Kristianingrum Dian Supangat Supangat Supangat Supangat Supranoto, Yehuda Tri Nugroho Suryono Suryono Tohari, Achmad Ilham Tristianti, Farmitalia Nisa Ulfa Elfiah Winda Amilia Wiwien Sugih Utami Yunita Armiyanti Yunita Dewi Anggraeni

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