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All Journal PHARMACON Biology, Medicine, & Natural Product Chemistry SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Pharmasipha Majalah Farmasetika Jurnal Kefarmasian AKFARINDO Pharma Xplore : Jurnal Sains dan Ilmu Farmasi JPK: Jurnal Proteksi Kesehatan Medfarm: Jurnal Farmasi dan Kesehatan Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Farmasi Etam Jurnal Pengabdian Masyarakat Tjut Nyak Dhien Journal of Biotechnology and Natural Science Jurnal Pepadu Media Farmasi Jurnal Sains dan Kesehatan Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Nurillahi Febria Leswana
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Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Edukasi dan Pelatihan Pembuatan Sabun Organik Eco-Friendly dari Bahan Alam Lemon dan Kayu Manis di KSP Credit Union Daya Lestari TP. Selili Samarinda Maria Elvina Tresia Butar-Butar; Nurillahi Febria Leswana; Agnes Elisa
ABDIMASKU : Jurnal Pengabdian Masyarakat UTND Vol 3 No 2 (2024): Edisi Juli 2024 - Desember 2024
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/jpmtnd.v3i2.1236

Abstract

Penggunaan sabun merupakan salah satu cara mudah dan efektif untuk membersihkan dan mencegah infeksi atu penyakit dan banyak digunakan sebagai salah satu kebutuhan rumah tangga. Berbagai macam jenis sabun komersil sudah banyak beredar dipasaran. Namun, sabun yang beredar umumnya mengandung detergen kimia yang berpotensi menimbulkan pencemaran lingkungan, terutama perairan. Pengembangan produk sabun yang ramah lingkungan, seperti penggunaan bahan alami, dianggap lebih aman dan minum mencemari lingkungan. Oleh sebab itu, kegiatan Pengabdian kepada Masyarakat (PkM) ini melakukan edukasi dan pelatihan pembuatan sabun organik eco-friendly berbahan lemon dan kayu manis kepada anggota masyarakat di KSP Credit Union Daya Lestari TP. Selili Samarinda. Kegiatan ini diikuti oleh 30 peserta, melalui kegiatan edukasi, diskusi, dan praktek langsung pembuatan sabun, serta penutup. Hasil yang diperoleh pada kegiatan PkM ini adalah produk sabun menggunakan bahan alami lemon dan kayu manis. Tingginya antusias peserta saat proses presentasi edukasi dan kegiatan pelatihan pembuatan sabun yang dihasilkan menjadi bukti ketercapaian PkM yang dilakukan. Pada kegiatan PkM ini dapat menjadi masukkan bagi peserta untuk meningkatkan pengetahuan, kreativitas, dan jiwa kewirausahaan
Antihypercholesterolemic Activity of Tahongai Leaf infusion (Kleinsovia hospita L.) In Mice (Mus musculus L.) Sianturi, Sister; Sinaga, Clara Ritawany; Leswana, Nurillahi Febria; Butar-Butar, Maria Elvina Tresia
Biology, Medicine, & Natural Product Chemistry Vol 14, No 1 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.141.233-238

Abstract

Tahongai (Kleinhovia hospita L.) is an indigenous plant of East Kalimantan known for its health benefits, including antibacterial, anti-inflammatory, antioxidant, anticancer, and antidiabetic properties. This study evaluates the antihypercholesterolemic activity of Tahongai leaf infusion in hypercholesterolemic mice (Mus musculus L.), induced by egg yolk. The test groups included a positive control (simvastatin), a negative control (distilled water), and three treatment groups with Tahongai leaf infusion at concentrations of 15%, 30%, and 60%. The results indicated that the highest reduction in cholesterol levels was observed in the P1 group (15% infusion) with an average decrease of 30.84%, followed by P2 (30% infusion) at 24.79%, and P3 (60% infusion) at 9.31%. The positive control group showed an average reduction of 8.64%. Statistical analysis using One-Way ANOVA revealed a significant difference (p<0.05) in cholesterol level reduction among the treatment groups.
Formulation of Keruing (Dipterocarpus grandiflorus) Oleoresin Aromatherapy Candles Butar-Butar, Maria Elvina Tresia; Agus, Adhe Septa Ryant; Leswana, Nurillahi Febria; Fernandes, Andrian
Jurnal Sains dan Kesehatan Vol. 6 No. 4 (2024): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v6i4.2331

Abstract

Aromatherapy is an alternative treatment method that utilizes essential oils and volatile components, such as terpenes and aromatic compounds. The active compounds of keruing oleoresin are phthalic acid, namely phthalic acid di(3-methoxybenzyl) ester and phthalic acid, 5-ethyl-1,3-dioxan-5-yl octyl ester causing keruing oleoresin to have a distinctive fragrance. The purpose of this study was to formulate keruing oleoresin in aromatherapy candle preparations. This research method includes base optimization, formulation of keruing oleoresin aromatherapy candles with concentrations of 0%; 2.5%; 5%; 7.5%; and 10%, and evaluation of aromatherapy candles including organoleptic testing, melting point, and burning time. The results of organoleptic testing of aromatherapy candles in shape, aroma, and color showed that F4 with 10% oleoresin concentration had a more dominant aroma and color. Melting point and burning time tests showed F1 with a concentration of 2.5% had a higher melting point of 54.6°C and a longer burning time of 144 minutes. Keywords:          Dipterocarpus grandiflorus, oleoresin, aromatherapy candle
ANALISIS RHODAMIN B PADA LIPSTIK IMPOR YANG BEREDAR DI PASAR PAGI KOTA SAMARINDA DENGAN SPEKTROFOTOMETRI UV-VISIBLE Ruth Gratia Dwi Pangestika; Nurillahi Febria Leswana; Adhe Septa Ryant Agus
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 11 No. 1 (2025): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v11i1.848

Abstract

Rhodamine B is commonly used as a dye for textiles (silk, wool, cotton), paint, paper, and clothing. Prolonged ingestion or exposure may irritate the respiratory tract, eyes, and skin, cause nausea and vomiting, and potentially lead to liver cancer or even cell death. This study aims to identify the presence of Rhodamine B dye in imported lipsticks sold at Pasar Pagi, Samarinda City. The research involved both qualitative and quantitative analyses. The qualitative test was conducted using Thin Layer Chromatography (TLC) with an eluent mixture of ethyl acetate : ethanol : ammonia (11:2:1), while the quantitative test employed UV-Vis spectrophotometry. The qualitative results using TLC showed that sample H had an Rf value of 0.529 cm, which closely resembled the standard Rhodamine B Rf value of 0.623 cm. The quantitative analysis revealed Rhodamine B concentrations in sample A (0.12%), sample B (0.19%), sample C (0.16%), sample F (0.20%), sample G (0.16%), sample H (0.37%), sample I (0.27%), and sample J (0.03%). The validity test indicated a linear result. The precision test showed Relative Standard Deviation (RSD) values of 1.7% for samples G, H, and I. The accuracy test yielded recovery percentages in sample G of 92% (2 ppm), 99% (4 ppm), and 86% (6 ppm); and in sample H of 88% (2 ppm), 98% (4 ppm), and 94% (6 ppm).
PEMBERDAYAAN UMKM KELURAHAN SUNGAI KAPIH MELALUI INOVASI PANGAN FUNGSIONAL JAMUR TIRAM FORTIFIKASI DAUN PANDAN UNTUK MENDUKUNG SDG’S3 Leswana, Nurillahi Febria; Taufiqurrahman, Muh; Hutagalung, Remita Ully
Jurnal Pepadu Vol 6 No 4 (2025): Jurnal Pepadu
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/pepadu.v6i4.8313

Abstract

This community service program in Sungai Kapih Village, Samarinda City, was implemented to strengthen the capacity of micro, small, and medium enterprises (MSMEs) through the development of functional food innovations based on oyster mushrooms (Pleurotus ostreatus) fortified with pandan leaves (Pandanus amaryllifolius). The program was motivated by the limited product diversification and underutilization of local ingredients as sources of functional food. A participatory approach was applied, consisting of needs assessment, socialization on the concept of functional food, technical training, production and packaging assistance, as well as monitoring and evaluation. The results showed significant improvements in participants’ knowledge of functional foods and technical skills in producing oyster mushroom–pandan fortified products, such as noodles and nuggets. Pre-test and post-test evaluations revealed an increase in processing skills from 40% to 80%, and a rise in positive attitudes toward innovation from 35% to 85%. The developed products demonstrated higher nutritional value and better sensory attributes, offering strong market potential and enhancing MSME competitiveness. Beyond economic benefits, this innovation also contributes to public health, as oyster mushrooms provide protein, fiber, and bioactive compounds, while pandan leaves enrich antioxidant properties and sensory appeal. The program aligns with the Sustainable Development Goal (SDG) 3 on Good Health and Well-Being, while simultaneously supporting local food security and sustainable community empowerment  
Antihyperuricemic Activity of Tahongai (Kleinhovia hospita L.) Leaf Infusion in Mice (Mus musculus L.) Sianturi, Sister; Sinaga, Clara Ritwany; Leswana, Nurillahi Febria; Butar-Butar, Maria Elvina Tresia; Simanullang, Raymon
Journal of Biotechnology and Natural Science Vol. 5 No. 2 (2025): December
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/jbns.v5i2.14723

Abstract

Tahongai (Kleinhovia hospita L.) is recognized as a traditional medicinal plant originating from East Kalimantan. This species possesses various bioactive properties that contribute to health benefits, particularly from its leaves, which contain active compounds such as flavonoids, alkaloids, saponins, and terpenoids. These bioactive constituents have been reported to exhibit anti-hyperuricemic properties. This study aimed to evaluate the anti-hyperuricemic activity of K. hospita leaf infusion in hyperuricemic mice (Mus musculus L.), which were induced using chicken liver juice. The test material used was an infusion prepared from K. hospita leaves. The experimental design consisted of five treatment groups: a positive control group receiving allopurinol, a negative control group receiving distilled water, and three treatment groups administered K. hospita leaf infusion at varying concentrations of P1=15%, P2=30%, and P3=60%. The results indicated that the highest mean reduction in uric acid levels was observed in the P2 group, which received a 30% concentration of K. hospita leaf infusion, with an average percentage decrease of 19.12%. However, statistical analysis using One-Way ANOVA revealed a p-value greater than 0.05, indicating that there was no significant difference in uric acid reduction among the treatment groups.
Pemberdayaan masyarakat desa sungai bawang melalui pelatihan diversifikasi olahan lele dan pemasaran digital Muh. Taufiqurrahman; Maria Elvina Tresia Butar-Butar; Remita Ully Hutagalung; Maria Floriana Ping; Nurillahi Febria Leswana; Angel Natalia Nainggolan; Falen Sindi Ayugistia
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 9, No 3 (2025): May
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v9i3.31056

Abstract

AbstrakDesa Budaya Sungai Bawang merupakan salah satu desa binaan STIKES Dirgahayu Samarinda yang memiliki potensi besar dalam pengembangan program ketahanan pangan dan peningkatan derajat kesehatan masyarakat. Pada tahun 2024, melalui anggaran desa, masyarakat menerima bantuan bibit ikan lele sebagai bentuk inisiasi budidaya perikanan di pekarangan rumah. Melihat potensi ini, kegiatan pengabdian kepada masyarakat dilakukan untuk mendukung hilirisasi hasil budidaya ikan lele dalam bentuk produk olahan pangan yang bernilai ekonomi tinggi serta berdaya saing pasar. Kegiatan pengabdian dilaksanakan melalui tiga tahapan utama, yaitu penyuluhan, pelatihan, dan pendampingan izin edar Pangan Industri Rumah Tangga (PIRT). Penyuluhan diberikan dengan metode presentasi dan diskusi interaktif, yang membahas pentingnya diversifikasi produk olahan ikan dan pembentukan kelompok usaha. Pelatihan dilakukan secara langsung dengan metode demonstrasi pembuatan produk berupa nugget dan sosis lele, melibatkan 30 peserta dari anggota PKK. Selanjutnya, dilakukan pendampingan teknis dalam proses pengurusan izin edar PIRT agar produk dapat dipasarkan secara legal dan luas. Hasil kegiatan menunjukkan adanya peningkatan pengetahuan dan keterampilan peserta dalam mengolah hasil budidaya ikan. Kegiatan ini juga mendorong terbentuknya satu kelompok usaha baru yang siap memproduksi pangan olahan secara mandiri. Dampak jangka pendek berupa peningkatan partisipasi masyarakat dalam kegiatan ekonomi produktif, sedangkan dampak jangka panjang diharapkan berupa peningkatan pendapatan rumah tangga dan kemandirian ekonomi berbasis potensi lokal. Kata kunci: pelatihan;  digitalisasi marketing; ikan lele. AbstractSungai Bawang Cultural Village is one of the villages fostered by STIKES Dirgahayu Samarinda which has great potential in developing food security programs and improving public health. In 2024, through the village budget, the community received assistance in the form of catfish seeds as a form of initiation of fish farming in their yards. Seeing this potential, community service activities were carried out to support the downstreaming of catfish cultivation results in the form of processed food products that have high economic value and are competitive in the market. Community service activities were carried out through three main stages, namely counseling, training, and assistance for the distribution permit for Household Industry Food (PIRT). Counseling was provided using presentation and interactive discussion methods, which discussed the importance of diversifying processed fish products and forming business groups. The training was carried out directly using a demonstration method for making products in the form of catfish nuggets and sausages, involving 30 participants from PKK members. Furthermore, technical assistance was provided in the process of managing the PIRT distribution permit so that the products could be marketed legally and widely. The results of the activities showed an increase in the knowledge and skills of participants in processing fish farming products. This activity also encourages the formation of a new business group that is ready to produce processed food independently. The short-term impact is in the form of increasing community participation in productive economic activities, while the long-term impact is expected to be in the form of increasing household income and economic independence based on local potential. Keywords: training; digital marketing; catfish.
PERBANDINGAN AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL 96% DAN EKSTRAK ASETON RIMPANG TEMULAWAK (Curcuma xanthorrhiza Roxb.) DENGAN METODE DPPH (1,1-diphenyl-2- picrylhydrazyl) Erika Sudin; Muh. Taufiqurrahman; Nurillahi Febria Leswana
Jurnal Farmasi Etam (JFE) Vol 5 No 1 (2025): Juni
Publisher : Unit Penelitian dan Pengabdian Kepada Masyarakat (UPPM) STIKES Dirgahayu Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52841/jfe.v5i1.846

Abstract

Temulawak (curcuma xanthorriza roxb.) merupakan salah satu jenis tanaman obat yang banyak digunakan masyarakat. Temulawak diketahui memiliki banyak manfaat salah satunya potensi sebagai antioksidan. Komponen aktif yang bertanggung jawab sebagai antioksidan dalam rimpang temulawak adalah kurkumin. kandungan senyawa aktif di dalam temulawak, terutama adalah kurkumin dan xanthorizol. Berbagai penelitian telah banyak dilakukan terhadap temulawak, terutama dari aspek khasiatnya. Kecendrungan masyarakat global pada semangat “back to nature” membuka peluang temulawak sebagai salah satu sumber bahan baku obat. Penelitian ini bertujuan untuk mengetahui perbandingan aktivitas antioksidan ekstrak etanol 96% dan aseton terhadap rimpang temulawak. Bahan baku yang digunakan adalah rimpang temulawak yang dijual wilayah kota samarinda. Pengujian antioksidan dilakukan dengan metode DPPH. Ekstrak temulawak memiliki aktivitas antioksidan tergolong aktif sehingga berpotensi sebagai antioksidan alami yang baik. Kata kunci : Kadar Kurkumin, Aktivitas Antioksidan, Temulawak
IDENTIFIKASI BAHAN KIMIA OBAT (BKO) PARACETAMOL PADA JAMU PEGAL LINU YANG BEREDAR DI PASAR PAGI KOTA SAMARINDA Viola Apristarani; Susana Linden; Nurillahi Febria Leswana
Jurnal Farmasi Etam (JFE) Vol 5 No 1 (2025): Juni
Publisher : Unit Penelitian dan Pengabdian Kepada Masyarakat (UPPM) STIKES Dirgahayu Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52841/jfe.v5i1.850

Abstract

Jamu pegal linu merupakan obat tradisional yang digunakan untuk mengurangi rasa lelah, nyeri otot, serta menyegarkan tubuh. Paracetamol merupakan obat yang paling umum digunakan masyarakat untuk meredakan gejala nyeri dan menurunkan demam. Penggunaan paracetamol dalam jamu dilarang karena dapat menyebabkan terjadinya interaksi yang tidak diinginkan antara obat tradisional dengan obat sintetik dan jika dikonsumsi dalam jangka panjang dapat menyebabkan gagal ginjal dan gangguan hati. Tujuan penelitian ini adalah untuk mengetahui adanya bahan kimia obat paracetamol dalam jamu pegal linu yang beredar di Pasar Pagi Kota Samarinda secara kualitatif yaitu menggunakan uji kromatografi lapis tipis dan kuantitatif yaitu menggunakan metode spektrofotometri UV-Vis. Serta memenuhi uji validasi dengan parameter validasi metode dalam penelitian meliputi linieritas, limit of detection (LOD) dan limit of Quantification (LOQ). Sampel yang diuji sebanyak 10 sampel. Hasil pengamatan pada uji kualitatif menggunakan plat KLT dengan fase gerak kloroform : etanol (8:1) terdapat sampel yang positif mengandung paracetamol yaitu sampel dengan nilai Rf A (0,135), B (0,121), C (0,121), D (0,189) dan E (0,135) yang mendekati dengan standar paracetamol Rf (0,135). Pada uji kuantitatif menggunakan spektrofotometri UV-Vis dengan panjang gelombang maksimum 242 nm. Kadar rata-rata paracetamol dalam 10 sampel yaitu 0.41 % - 74,87% hal ini menunjukkan bahwa jamu pegal linu yang beredar tidak memenuhi syarat BPOM karena mengandung paracetamol. Kata Kunci : Jamu pegal linu, Paracetamol, Kromatografi Lapis Tipis, Spektrofotometri UV-Vis
PERBANDINGAN EFEKTIVITAS BIOADSORBEN KULIT PISANG AMBON DAN KULIT SUKUN TERHADAP LOGAM Pb(II) PADA LIMBAH CAIR LABORATORIUM FARMASI DENGAN METODE SPEKTROFOTOMETRI UV-VISIBLE Desti Natalia Lantika T; Nurillahi Febria Leswana; Maria Elvina Tresia Butar-Butar
Jurnal Farmasi Etam (JFE) Vol 5 No 2 (2025): Desember
Publisher : Unit Penelitian dan Pengabdian Kepada Masyarakat (UPPM) STIKES Dirgahayu Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52841/jfe.v5i2.848

Abstract

Kegiatan manusia mengakibatkan pencemaran limbah logam berat ke ling- kungan dalam aneka macam bentuk, termasuk limbah kegiatan industri, limbah laboratorium, pembuangan transportasi, limbah kota, kawasan pembuangan sampah, limbah pertambangan, dan pelapisan listrik. Tujuan dari penelitian ini adalah menentukan perbandingan efektivitas bioadsorbeni serbuk kulit buah pisang ambon dan serbuk kulit buah sukun terdapat logam Pb limbah cair laboratorium farmasi dan mengetahui perbandingan kemampuan bioadsorben serbuk kulit buah pisang ambon dan serbuk kulit buah sukun terhadap logam Pb limbah cair laboratorium farmasi. Penelitian ini menggunakan metode Spektrofotometri UV-Visible. Berdasarkan kurva hubungan absorbansi terhadap waktu diperoleh kondisi yang stabil yaitu pH 4 pada menit ke 45 sampai 60. Pada penelitian ini menunjukkan pisang ambon waktu optimum kulit pisang ambon adalah 60 menit pada 23,4% dan efektivitas dari pisang ambon yaitu sebesar 29,7% dengan kondisi pH optimum pada pH 5. Sedangkan kulit sukun pada waktu optimum 60 menit 27,4%. Dari data didapat dikatakan bahwa bioadsroben kulit sukun memiliki efektivitas yang cukup baik dalam proses penyerapan Pb dengan nilai efektivitas sebesar 79,6%. sedangkan sukun dengan kondisi optimum pH 5, waktu kontak 60 menit dan massa 125 mg semakin bertambahnya bobot maka semakin menurunnya absorbansi dari limbah. Kata Kunci : Kulit Pisang Ambon, Kulit Sukun, Timbal Pb (II), Limbah Laboratorium Farmasi
Co-Authors Abdul Rahim Adhitasari Suratman Agnes Elisa Agus, Adhe Septa Ryant Andrian Fernandes, Andrian Angel Natalia Nainggolan Atika Cristina Bua, Tin Sanda Liling Butar-Butar, Maria Elvina Tresia Clara Ritawany Sinaga Dari, Dewi Wulan Desti Natalia Lantika T Dwi Siswanta Erika Sudin Falen Sindi Ayugistia Hiasinta Meliana Hangin Husna husna husna Hutagalung, Remita Ully Iju, Sesilia Karolina Jenly Adinata Karolina Yordan Linden, Susana Maria Elvina Tresia Butar - Butar Maria Elvina Tresia Butar-Butar Maria Meylennia Bulan Monika Julan Morijan, Risky asrina Nadia Panca Wati Pijaryani, Indria Ping, Maria Floriana Remita Ully Hutagalung Ruth Gratia Dwi Pangestika Silaban Erllin Tirza Stevany Simanullang, Raymon Sinaga, Clara Ritwany Sister Sianturi Sulistiani Sulistiani, Sulistiani susana linden Susana Linden Susana Linden Taufiqurrahman, Muh Viola Apristarani Yesi Bayaq