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All Journal PHARMACON Biology, Medicine, & Natural Product Chemistry SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Pharmasipha Majalah Farmasetika Jurnal Kefarmasian AKFARINDO Pharma Xplore : Jurnal Sains dan Ilmu Farmasi JPK: Jurnal Proteksi Kesehatan Medfarm: Jurnal Farmasi dan Kesehatan Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Farmasi Etam Jurnal Pengabdian Masyarakat Tjut Nyak Dhien Journal of Biotechnology and Natural Science Jurnal Pepadu Media Farmasi Jurnal Sains dan Kesehatan Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Nurillahi Febria Leswana
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Religion Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Edukasi dan Pelatihan Pembuatan Sabun Organik Eco-Friendly dari Bahan Alam Lemon dan Kayu Manis di KSP Credit Union Daya Lestari TP. Selili Samarinda Maria Elvina Tresia Butar-Butar; Nurillahi Febria Leswana; Agnes Elisa
ABDIMASKU : Jurnal Pengabdian Masyarakat UTND Vol 3 No 2 (2024): Edisi Juli 2024 - Desember 2024
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/jpmtnd.v3i2.1236

Abstract

Penggunaan sabun merupakan salah satu cara mudah dan efektif untuk membersihkan dan mencegah infeksi atu penyakit dan banyak digunakan sebagai salah satu kebutuhan rumah tangga. Berbagai macam jenis sabun komersil sudah banyak beredar dipasaran. Namun, sabun yang beredar umumnya mengandung detergen kimia yang berpotensi menimbulkan pencemaran lingkungan, terutama perairan. Pengembangan produk sabun yang ramah lingkungan, seperti penggunaan bahan alami, dianggap lebih aman dan minum mencemari lingkungan. Oleh sebab itu, kegiatan Pengabdian kepada Masyarakat (PkM) ini melakukan edukasi dan pelatihan pembuatan sabun organik eco-friendly berbahan lemon dan kayu manis kepada anggota masyarakat di KSP Credit Union Daya Lestari TP. Selili Samarinda. Kegiatan ini diikuti oleh 30 peserta, melalui kegiatan edukasi, diskusi, dan praktek langsung pembuatan sabun, serta penutup. Hasil yang diperoleh pada kegiatan PkM ini adalah produk sabun menggunakan bahan alami lemon dan kayu manis. Tingginya antusias peserta saat proses presentasi edukasi dan kegiatan pelatihan pembuatan sabun yang dihasilkan menjadi bukti ketercapaian PkM yang dilakukan. Pada kegiatan PkM ini dapat menjadi masukkan bagi peserta untuk meningkatkan pengetahuan, kreativitas, dan jiwa kewirausahaan
Antihypercholesterolemic Activity of Tahongai Leaf infusion (Kleinsovia hospita L.) In Mice (Mus musculus L.) Sianturi, Sister; Sinaga, Clara Ritawany; Leswana, Nurillahi Febria; Butar-Butar, Maria Elvina Tresia
Biology, Medicine, & Natural Product Chemistry Vol 14, No 1 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.141.233-238

Abstract

Tahongai (Kleinhovia hospita L.) is an indigenous plant of East Kalimantan known for its health benefits, including antibacterial, anti-inflammatory, antioxidant, anticancer, and antidiabetic properties. This study evaluates the antihypercholesterolemic activity of Tahongai leaf infusion in hypercholesterolemic mice (Mus musculus L.), induced by egg yolk. The test groups included a positive control (simvastatin), a negative control (distilled water), and three treatment groups with Tahongai leaf infusion at concentrations of 15%, 30%, and 60%. The results indicated that the highest reduction in cholesterol levels was observed in the P1 group (15% infusion) with an average decrease of 30.84%, followed by P2 (30% infusion) at 24.79%, and P3 (60% infusion) at 9.31%. The positive control group showed an average reduction of 8.64%. Statistical analysis using One-Way ANOVA revealed a significant difference (p<0.05) in cholesterol level reduction among the treatment groups.
Formulation of Keruing (Dipterocarpus grandiflorus) Oleoresin Aromatherapy Candles Butar-Butar, Maria Elvina Tresia; Agus, Adhe Septa Ryant; Leswana, Nurillahi Febria; Fernandes, Andrian
Jurnal Sains dan Kesehatan Vol. 6 No. 4 (2024): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v6i4.2331

Abstract

Aromatherapy is an alternative treatment method that utilizes essential oils and volatile components, such as terpenes and aromatic compounds. The active compounds of keruing oleoresin are phthalic acid, namely phthalic acid di(3-methoxybenzyl) ester and phthalic acid, 5-ethyl-1,3-dioxan-5-yl octyl ester causing keruing oleoresin to have a distinctive fragrance. The purpose of this study was to formulate keruing oleoresin in aromatherapy candle preparations. This research method includes base optimization, formulation of keruing oleoresin aromatherapy candles with concentrations of 0%; 2.5%; 5%; 7.5%; and 10%, and evaluation of aromatherapy candles including organoleptic testing, melting point, and burning time. The results of organoleptic testing of aromatherapy candles in shape, aroma, and color showed that F4 with 10% oleoresin concentration had a more dominant aroma and color. Melting point and burning time tests showed F1 with a concentration of 2.5% had a higher melting point of 54.6°C and a longer burning time of 144 minutes. Keywords:          Dipterocarpus grandiflorus, oleoresin, aromatherapy candle
ANALISIS RHODAMIN B PADA LIPSTIK IMPOR YANG BEREDAR DI PASAR PAGI KOTA SAMARINDA DENGAN SPEKTROFOTOMETRI UV-VISIBLE Ruth Gratia Dwi Pangestika; Nurillahi Febria Leswana; Adhe Septa Ryant Agus
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 11 No. 1 (2025): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v11i1.848

Abstract

Rhodamine B is commonly used as a dye for textiles (silk, wool, cotton), paint, paper, and clothing. Prolonged ingestion or exposure may irritate the respiratory tract, eyes, and skin, cause nausea and vomiting, and potentially lead to liver cancer or even cell death. This study aims to identify the presence of Rhodamine B dye in imported lipsticks sold at Pasar Pagi, Samarinda City. The research involved both qualitative and quantitative analyses. The qualitative test was conducted using Thin Layer Chromatography (TLC) with an eluent mixture of ethyl acetate : ethanol : ammonia (11:2:1), while the quantitative test employed UV-Vis spectrophotometry. The qualitative results using TLC showed that sample H had an Rf value of 0.529 cm, which closely resembled the standard Rhodamine B Rf value of 0.623 cm. The quantitative analysis revealed Rhodamine B concentrations in sample A (0.12%), sample B (0.19%), sample C (0.16%), sample F (0.20%), sample G (0.16%), sample H (0.37%), sample I (0.27%), and sample J (0.03%). The validity test indicated a linear result. The precision test showed Relative Standard Deviation (RSD) values of 1.7% for samples G, H, and I. The accuracy test yielded recovery percentages in sample G of 92% (2 ppm), 99% (4 ppm), and 86% (6 ppm); and in sample H of 88% (2 ppm), 98% (4 ppm), and 94% (6 ppm).
PEMBERDAYAAN UMKM KELURAHAN SUNGAI KAPIH MELALUI INOVASI PANGAN FUNGSIONAL JAMUR TIRAM FORTIFIKASI DAUN PANDAN UNTUK MENDUKUNG SDG’S3 Leswana, Nurillahi Febria; Taufiqurrahman, Muh; Hutagalung, Remita Ully
Jurnal Pepadu Vol 6 No 4 (2025): Jurnal Pepadu
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/pepadu.v6i4.8313

Abstract

This community service program in Sungai Kapih Village, Samarinda City, was implemented to strengthen the capacity of micro, small, and medium enterprises (MSMEs) through the development of functional food innovations based on oyster mushrooms (Pleurotus ostreatus) fortified with pandan leaves (Pandanus amaryllifolius). The program was motivated by the limited product diversification and underutilization of local ingredients as sources of functional food. A participatory approach was applied, consisting of needs assessment, socialization on the concept of functional food, technical training, production and packaging assistance, as well as monitoring and evaluation. The results showed significant improvements in participants’ knowledge of functional foods and technical skills in producing oyster mushroom–pandan fortified products, such as noodles and nuggets. Pre-test and post-test evaluations revealed an increase in processing skills from 40% to 80%, and a rise in positive attitudes toward innovation from 35% to 85%. The developed products demonstrated higher nutritional value and better sensory attributes, offering strong market potential and enhancing MSME competitiveness. Beyond economic benefits, this innovation also contributes to public health, as oyster mushrooms provide protein, fiber, and bioactive compounds, while pandan leaves enrich antioxidant properties and sensory appeal. The program aligns with the Sustainable Development Goal (SDG) 3 on Good Health and Well-Being, while simultaneously supporting local food security and sustainable community empowerment  
Antihyperuricemic Activity of Tahongai (Kleinhovia hospita L.) Leaf Infusion in Mice (Mus musculus L.) Sianturi, Sister; Sinaga, Clara Ritwany; Leswana, Nurillahi Febria; Butar-Butar, Maria Elvina Tresia; Simanullang, Raymon
Journal of Biotechnology and Natural Science Vol. 5 No. 2 (2025): December
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/jbns.v5i2.14723

Abstract

Tahongai (Kleinhovia hospita L.) is recognized as a traditional medicinal plant originating from East Kalimantan. This species possesses various bioactive properties that contribute to health benefits, particularly from its leaves, which contain active compounds such as flavonoids, alkaloids, saponins, and terpenoids. These bioactive constituents have been reported to exhibit anti-hyperuricemic properties. This study aimed to evaluate the anti-hyperuricemic activity of K. hospita leaf infusion in hyperuricemic mice (Mus musculus L.), which were induced using chicken liver juice. The test material used was an infusion prepared from K. hospita leaves. The experimental design consisted of five treatment groups: a positive control group receiving allopurinol, a negative control group receiving distilled water, and three treatment groups administered K. hospita leaf infusion at varying concentrations of P1=15%, P2=30%, and P3=60%. The results indicated that the highest mean reduction in uric acid levels was observed in the P2 group, which received a 30% concentration of K. hospita leaf infusion, with an average percentage decrease of 19.12%. However, statistical analysis using One-Way ANOVA revealed a p-value greater than 0.05, indicating that there was no significant difference in uric acid reduction among the treatment groups.
Relationship of Knowledge and Motivation with Compliance in Taking Anti-Tuberculosis Drugs in TB Patients at North Bontang Health Center 1 husna, Husna husna; Leswana, Nurillahi Febria; Butar-Butar, Maria Elvina Tresia
MEDFARM: Jurnal Farmasi dan Kesehatan Vol 14 No 2 (2025): Medfarm: Jurnal Farmasi dan Kesehatan
Publisher : LPPM Akafarma Sunan Giri Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.48191/medfarm.v14i2.619

Abstract

Tuberculosis (TB) treatment requires six months of continuous Anti-Tuberculosis Drug (OAT) therapy; non-compliance leads to treatment failure and Multi-Drug Resistant TB. This study aimed to analyze the relationship between patient knowledge and motivation with medication compliance among TB patients at the North Bontang Health Center 1, Indonesia. This cross-sectional study involved tuberculosis patients at North Bontang 1 Health Center. From a total registered population of 325 patients, a strict purposive sampling technique was applied based on inclusion and exclusion criteria, resulting in 30 eligible patients who participated in this study during the period of December 2024 to January 2025. Data on knowledge and motivation were collected using structured questionnaires; compliance was determined via triangulation (interviews, TB Form 01, PMO). Bivariate analysis used the Fisher's Exact Test (n=30). Results showed the majority demonstrated good knowledge (83.3%) and high motivation (90.0%), resulting in a high overall compliance rate (93.3%). Statistical analysis revealed a significant relationship between knowledge and compliance (p=0.006). No statistically significant relationship was found between motivation and compliance (p=0.193), likely due to data homogeneity
Pemberdayaan masyarakat desa sungai bawang melalui pelatihan diversifikasi olahan lele dan pemasaran digital Muh. Taufiqurrahman; Maria Elvina Tresia Butar-Butar; Remita Ully Hutagalung; Maria Floriana Ping; Nurillahi Febria Leswana; Angel Natalia Nainggolan; Falen Sindi Ayugistia
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 9, No 3 (2025): May
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v9i3.31056

Abstract

AbstrakDesa Budaya Sungai Bawang merupakan salah satu desa binaan STIKES Dirgahayu Samarinda yang memiliki potensi besar dalam pengembangan program ketahanan pangan dan peningkatan derajat kesehatan masyarakat. Pada tahun 2024, melalui anggaran desa, masyarakat menerima bantuan bibit ikan lele sebagai bentuk inisiasi budidaya perikanan di pekarangan rumah. Melihat potensi ini, kegiatan pengabdian kepada masyarakat dilakukan untuk mendukung hilirisasi hasil budidaya ikan lele dalam bentuk produk olahan pangan yang bernilai ekonomi tinggi serta berdaya saing pasar. Kegiatan pengabdian dilaksanakan melalui tiga tahapan utama, yaitu penyuluhan, pelatihan, dan pendampingan izin edar Pangan Industri Rumah Tangga (PIRT). Penyuluhan diberikan dengan metode presentasi dan diskusi interaktif, yang membahas pentingnya diversifikasi produk olahan ikan dan pembentukan kelompok usaha. Pelatihan dilakukan secara langsung dengan metode demonstrasi pembuatan produk berupa nugget dan sosis lele, melibatkan 30 peserta dari anggota PKK. Selanjutnya, dilakukan pendampingan teknis dalam proses pengurusan izin edar PIRT agar produk dapat dipasarkan secara legal dan luas. Hasil kegiatan menunjukkan adanya peningkatan pengetahuan dan keterampilan peserta dalam mengolah hasil budidaya ikan. Kegiatan ini juga mendorong terbentuknya satu kelompok usaha baru yang siap memproduksi pangan olahan secara mandiri. Dampak jangka pendek berupa peningkatan partisipasi masyarakat dalam kegiatan ekonomi produktif, sedangkan dampak jangka panjang diharapkan berupa peningkatan pendapatan rumah tangga dan kemandirian ekonomi berbasis potensi lokal. Kata kunci: pelatihan;  digitalisasi marketing; ikan lele. AbstractSungai Bawang Cultural Village is one of the villages fostered by STIKES Dirgahayu Samarinda which has great potential in developing food security programs and improving public health. In 2024, through the village budget, the community received assistance in the form of catfish seeds as a form of initiation of fish farming in their yards. Seeing this potential, community service activities were carried out to support the downstreaming of catfish cultivation results in the form of processed food products that have high economic value and are competitive in the market. Community service activities were carried out through three main stages, namely counseling, training, and assistance for the distribution permit for Household Industry Food (PIRT). Counseling was provided using presentation and interactive discussion methods, which discussed the importance of diversifying processed fish products and forming business groups. The training was carried out directly using a demonstration method for making products in the form of catfish nuggets and sausages, involving 30 participants from PKK members. Furthermore, technical assistance was provided in the process of managing the PIRT distribution permit so that the products could be marketed legally and widely. The results of the activities showed an increase in the knowledge and skills of participants in processing fish farming products. This activity also encourages the formation of a new business group that is ready to produce processed food independently. The short-term impact is in the form of increasing community participation in productive economic activities, while the long-term impact is expected to be in the form of increasing household income and economic independence based on local potential. Keywords: training; digital marketing; catfish.
ANALISIS KANDUNGAN ZAT WARNA METHANYL YELLOW PADA TAHU KUNING YANG BEREDAR DI KECAMATAN SAMARINDA ULU DENGAN METODE SPEKTROFOTOMETRI UV-VISIBLE Cristina, Atika; Linden, Susana; Leswana, Nurillahi Febria
Jurnal Farmasi Etam (JFE) Vol 4 No 2 (2024): Desember
Publisher : Unit Penelitian dan Pengabdian Kepada Masyarakat (UPPM) STIKES Dirgahayu Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52841/jfe.v4i2.819

Abstract

Research on methanyl yellow dye in yellow tofu was carried out to determine the presence or absence of methanyl yellow and to determine the levels of methanyl yellow in yellow tofu samples circulating on the market in Samarinda Ulu sub- district by Thin Layer Chromatography and UV-Vis Spectrophotometry. This study began with a TLC test on 10 samples of yellow tofu so that the results obtained after the test obtained a standard Rf value of 0.946 while in the 10 samples of yellow tofu, the presence of methanyl yellow dye was not identified. In the UV-Vis Spectrophotometry test, the maximum wavelength was 422 nm with an absorbance of 0.279, which is still within the standard range for the maximum wavelength of methanyl yellow, namely 390-450 nm. The standard curve equation results obtained are y = 0.1062x – 0.0719 with a correlation coefficient (r) of 0.9989, this indicates that the correlation is very strong if the R2 value obtained is above 0.9 but less than 1.0. The UV-Vis spectrophotometry method was also carried out on 10 samples of yellow tofu although it had been tested using the thin layer chromatography method and did not identify the presence of methanyl yellow dye. The aim was to see the wavelength produced by each sample along with its absorbance value.
PERBANDINGAN AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL 96% DAN EKSTRAK ASETON RIMPANG TEMULAWAK (Curcuma xanthorrhiza Roxb.) DENGAN METODE DPPH (1,1-diphenyl-2- picrylhydrazyl) Erika Sudin; Muh. Taufiqurrahman; Nurillahi Febria Leswana
Jurnal Farmasi Etam (JFE) Vol 5 No 1 (2025): Juni
Publisher : Unit Penelitian dan Pengabdian Kepada Masyarakat (UPPM) STIKES Dirgahayu Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52841/jfe.v5i1.846

Abstract

Temulawak (curcuma xanthorriza roxb.) merupakan salah satu jenis tanaman obat yang banyak digunakan masyarakat. Temulawak diketahui memiliki banyak manfaat salah satunya potensi sebagai antioksidan. Komponen aktif yang bertanggung jawab sebagai antioksidan dalam rimpang temulawak adalah kurkumin. kandungan senyawa aktif di dalam temulawak, terutama adalah kurkumin dan xanthorizol. Berbagai penelitian telah banyak dilakukan terhadap temulawak, terutama dari aspek khasiatnya. Kecendrungan masyarakat global pada semangat “back to nature” membuka peluang temulawak sebagai salah satu sumber bahan baku obat. Penelitian ini bertujuan untuk mengetahui perbandingan aktivitas antioksidan ekstrak etanol 96% dan aseton terhadap rimpang temulawak. Bahan baku yang digunakan adalah rimpang temulawak yang dijual wilayah kota samarinda. Pengujian antioksidan dilakukan dengan metode DPPH. Ekstrak temulawak memiliki aktivitas antioksidan tergolong aktif sehingga berpotensi sebagai antioksidan alami yang baik. Kata kunci : Kadar Kurkumin, Aktivitas Antioksidan, Temulawak
Co-Authors Abdul Rahim Adhitasari Suratman Agnes Elisa Agus, Adhe Septa Ryant Andrian Fernandes, Andrian Angel Natalia Nainggolan Bua, Tin Sanda Liling Butar-Butar, Maria Elvina Tresia Clara Ritawany Sinaga Cristina, Atika Desti Natalia Lantika T Dwi Siswanta Erika Sudin Falen Sindi Ayugistia Hiasinta Meliana Hangin Husna, Husna Husna Hutagalung, Remita Ully Iju, Sesilia Karolina Jenly Adinata Linden, Susana Maria Elvina Tresia Butar-Butar Maria Meylennia Bulan Monika Julan Morijan, Risky asrina Muh. Taufiqurrahman Pijaryani, Indria Ping, Maria Floriana Remita Ully Hutagalung Ruth Gratia Dwi Pangestika Silaban Erllin Tirza Stevany Simanullang, Raymon Sinaga, Clara Ritwany Sister Sianturi Sulistiani Sulistiani, Sulistiani susana linden Susana Linden Taufiqurrahman, Muh Viola Apristarani