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Phosphate Accumulation Using MgO-Fe3O4/Agarose/Oxalic Acid Gel as a Diffusive Gradient in Thin Films (DGT) Binding Layer Dinira, Layta; Rafif, Sullahudin Ahmad; Ulayya, Salwa; Rumhayati, Barlah; Darjito, Darjito; Sabarudin, Akhmad
EduChemia: Jurnal Kimia dan Pendidikan Vol 10, No 1 (2025)
Publisher : Department of Chemistr Education Faculty of Teacher Training and Education Universitas Su

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30870/educhemia.v10i1.29113

Abstract

Monitoring phosphate concentration in waters is critical because excessive phosphate can lead to the death of aquatic organisms. Phosphate can be monitored via a passive sampler called Diffusion Gradient in Thin Films (DGT). This study combines MgO and Fe3O4 impregnated in agarose crosslinked with oxalic acid to accumulate phosphate from the solution as a DGT binding gel. The parameters observed in this study were MgO/Fe3O4 mass ratio (1:3, 1:1, 3:1), accumulation time (20, 40, 60, 120, 240, and 1440 min), phosphate concentration (0.2, 0.4, 0.6, 0.8, and 1 mg/L) and pH (4, 5, 6, 7, and 8) on phosphate accumulation. XRD pattern confirmed that the adsorbents used were MgO and Fe3O4. SEM analysis showed that the gel had an average pore size of 31.78 μm, and the adsorbents were evenly distributed. Gel with MgO/Fe3O4 mass ratio 3:1 can adsorb phosphate up to 97.19 ± 0.36%. The phosphate accumulation reached optimum after a minimum adsorption time of 4 hours and when the phosphate concentration in the solution was 0.4 mg/L. The solution's pH had no significant effect on phosphate accumulation. This study shows that MgO-Fe3O4/agarose/oxalic acid gel is an excellent binding gel to accumulate phosphate from water.
Effect of Ethanol-water Concentration as Extraction Solvent on Antioxidant Activity of Acalypha indica Fadhila, Salma Iza; Hayati, Elok Kamilah; Rafi, Mohamad; Sabarudin, Akhmad
al Kimiya: Jurnal Ilmu Kimia dan Terapan Vol. 10 No. 2 (2023): al Kimiya: Jurnal Ilmu Kimia dan Terapan
Publisher : Department of Chemistry, Faculty of Science and Technology, UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/ak.v10i2.30081

Abstract

Acalypha indica is an abundant and obtainable wild weed plant in Indonesia. This is a possible opportunity to enhance its utility. The effect of free radicals is one of the factors that contribute to oxidative stress in the body, which can lead to cell damage and trigger various diseases. Plants rich in antioxidants can inhibit free radical reactions and protect the body from oxidative stress. In this study, we conducted the identification of major metabolite compounds using UHPLC-Q-Orbitrap HRMS from 70% ethanol extracts of Acalypha indica. We also performed phytochemical and antioxidant activity tests with various concentrations of ethanol-water solvents including water, 30%, 50%, 70% ethanol, and absolute ethanol to determine the optimal extraction conditions and the influence of solvent concentration on the antioxidant activity of Acalypha indica extract. The results of UHPLC-Q-Orbitrap HRMS identification showed that the 70% ethanol extract of Acalypha indica contains 10 major compounds suspected to correlate with its antioxidant activity. These include five flavonoids compounds (palasitrin, vitexin 2"-o-p-coumarate, isorhamnetin 3- (3",6"-di-p-coumarylglucoside), peucenin, and sulfuretin), two amino acid compounds (2-amino-3-carboxymuconic acid semialdehyde and N-Acetyl-L-phenylalanine), two carboxylic acid compound (citric acid and traumatic acid), and one phenolic compound (quinic acid). Phytochemical tests show positive results for flavonoids, tannins, alkaloids, and triterpenoids in each of water, 30%, 50%, 70% ethanol, and absolute ethanol extracts. The best antioxidant activity was obtained from the 70% ethanol extract with an IC50 value of 47.064 ppm, categorizing it as an extremely strong antioxidant.
Urine Glucose Detection Via Gold Nanoparticle Formation Using 3D-Connector Microfluidic Paper Based Analytical Devices Putri, Krista Firdaus Suwarno; Sulistyarti, Hermin; Sabarudin, Akhmad
al Kimiya: Jurnal Ilmu Kimia dan Terapan Vol. 11 No. 1 (2024): al Kimiya: Jurnal Ilmu Kimia dan Terapan
Publisher : Department of Chemistry, Faculty of Science and Technology, UIN Sunan Gunung Djati Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15575/ak.v11i1.35245

Abstract

A metabolic disorders that have experienced a significant increase in the world are diabetes mellitus. Diabetes is caused by two main factors: the first is damage to pancreatic beta cells, which prevents insulin from being produced, and the second is impaired insulin secretion and function. Chronic diabetes, if not treated properly, can lead to acute complications including eye, kidney, lung, nerve, and even death. Diabetes can be diagnosed through blood and urine. In general, glucose detection is carried out using invasive methods that use blood samples, which can cause pain and discomfort for users. Current research is developing non-invasive glucose detection using urine samples. This research aims to develop non-invasive glucose detection technology using 3D-connector μPADs (Microfluidic Paper Based Analytical Devices) which have the advantages of being safe, easy, and simple. The three-dimensional connector on the device functions as a connector to facilitate the coordination of fluid flow in the sample zone and detection zone. The glucose detection method uses gold (III) chloride as a gold nanoparticle (AuNPs) precursor, an aqueous extract of Acalypha indica Linn as a stabilizing agent, sodium hydroxide (NaOH) as a catalyst, and glucose in artificial urine as a sample. Method validation results using imageJ software indicated linearity with a coefficient of determination value (R2) of 0.9714, precision with a %RSD value (Relative Standard Deviation) of 2.69, and an accuracy level ranging from 92.22-99.23%.
Penyaring Air Keran untuk Pemenuhan Air Bersih di Desa Talangsuko, Kecamatan Turen, Kabupaten Malang Layta Dinira; Mulyasuryani, Ani; Rumhayati, Barlah; Sabarudin, Akhmad
Rengganis Jurnal Pengabdian Masyarakat Vol. 5 No. 2 (2025): November 2025
Publisher : Pendidikan Matematika, FKIP Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/rengganis.v5i2.877

Abstract

Desa Talangsuko, Kecamatan Turen, Kabupaten Malang is classified as an area with moderate risk of perilaku hidup bersih dan sehat (PHBS), indicating that PHBS management is not yet optimal. This community service aimed to improve household water management in Desa Talangsuko by implementing filtration and adsorption technology through tap water filters. The activities included water sampling, tap water filter design, education on clean water through counseling and hands-on demonstrations, and installation of tap water filters. The results showed an improvement in household water quality after the use of the tap water filters, as indicated by the reduction of chemical contaminants such as fluoride, nitrate, and water hardness. The counseling and hands-on demonstrations increased community awareness about clean water and the importance of regularly replacing water filter materials. These results suggest that this program demonstrated a positive impact on household water management in Desa Talangsuko.