Claim Missing Document
Check
Articles

Found 25 Documents
Search

Antioxidant Effect of Bilimbi Fruit (Averrhoa Bilimbi Linn) Extract on SGPT Level in Mice Induced by Reheated Palm Oil Mulyono, Rosi Dwi; Putranto, R Prihandjojo Andri; ., Sarsono
Nexus Kedokteran Translasional Vol 5, No 2 (2016): Nexus Kedokteran Translasional
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (14.209 KB)

Abstract

Introduction: Reheated palm oil was known to contain free radicals that cause damage and death of liver cell, antioxidant is needed to prevent. One source of antioxidant is Bilimbi fruit. This research aims to determine the effect of Bilimbi fruit extract and variant in dosage of Bilimbi fruit extract on levels of Serum Glutamic Piruvic Transaminase in mice induced by reheated palm oil. Methods: This research was a laboratory experimental with a post-test only control grup design. The subject of research was Swiss Webster mice, male, age 2-3 mounths, weight + 20 grams. The subject ware chosen by incidental sampling for 30 individuals, devided randomly into 5 groups, each groups consist of 6 mice. The control group (K) was given aquadest (0,3 ml/20 g BW and 0,2 ml/20 g BW). Mice in treated group 1 (P1) was given aquadest (0,3 ml/20 g BW) and reheated palm oil (0,2 ml/20 g BW). Mice in treated group 2 (P2), treated group 3 (P3) and treated group 4 (P4) was given Bilimbi fruit extract with dosage 5,6 mg/20 g BW; 11,2 mg/20 g BW; and 22,4 mg/20 g BW and reheated palm oil (0,2 ml/20 g BB). Bilimbi fruit extract was given 1 hour before reheated palm oil for 14 days. At the day-15, mice ware sacrificed and the animal blood was collected from pleksus retroorbitalis. The result was analyzed statistically by one way ANOVA and followed by LSD test (α =  0,05). Results: Mean of SGPT level in each group was K = 37,5 + 8,256 U/L; P1 = 50,92 + 8,267 U/L; P2 = 37,08 + 5,043 U/L; P3 = 43,34 + 7,834 U/L; P4 = 51,12 + 13,526 U/L. There wes significant difference between K – P1, K – P4, P1 – P2, and P2 – P4, there was not significant difference between K – P2, K – P3, P1 – P3, P1 – P4, P2 – P3, and P3 – P4. Conclusions: The extract of Bilimbi fruit decrease SGPT level in mice induced by reheated palm oil. An increase in dose of Bilimbi fruit extract cannot increase the influence to decrease SGPT level in mice induced by reheated palm oil. Keywords: Bilimbi fruit extract, SGPT, reheated palm oil, SGPT. 
Ekstrak Etanol Propolis Menurunkan Kadar IL-17 Serum pada Mencit Balb/C Model Asma Kronik Hadinoto, Sri Hartati; Sarsono, Sarsono; Aisyah, Siti; Prasetyo, Diding H.
Majalah Kedokteran Bandung Vol 45, No 4 (2013)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1249.341 KB)

Abstract

Interleukin-17 (IL-17) menginduksi perekrutan neutrofil ke dalam saluran napas dan berperan dalam patogenesis asma serta penentuan keparahan penyakit. Tujuan penelitian ini adalah menganalisis efek ekstrak etanol propolis (EEP) isolat Gunung Lawu terhadap kadar IL-17 serum pada mencit Balb/C model asma kronik. Penelitian ini merupakan penelitian eksperimental laboratoris dengan sampel 28 ekor mencit Balb/C jantan yang dibagi menjadi empat kelompok: kontrol, asma, asma+EEP, dan asma+antihistamin. Penelitian dilakukan di Laboratorium Histologi dan Biomedik, Fakultas Kedokteran, Universitas Sebelas Maret, Surakarta, selama periode April-September 2012. Model asma kronik dibuat dengan menginduksi mencit Balb/C jantan menggunakan injeksi intraperitoneal (i.p.) ovalbumin (OVA, 100 μg/mencit) dan aluminium hidroksida (10%, 50 mg/mencit) dalam phosphate-buffered saline (PBS). Hewan coba disensitisasi selama 6 minggu dengan inhalasi 2% (b/v) OVA aerosol dalam NaCl 0,9% selama 30 menit/hari setiap 3 hari/minggu, untuk kelompok asma, asma+EEP, dan asma+antihistamin. Mencit kontrol tidak diinokulasi selama penelitian. Deteksi kadar IL-17 serum menggunakan enzyme-linked immunosorbent assay (ELISA). Uji kadar IL-17 serum menggunakan analysis of variance (ANOVA) dan untuk menentukan perbedaan kemaknaan digunakan p<0,05. Kadar IL-17 serum kelompok kontrol menunjukkan 17,15±8,25 pg/mL dan antihistamin 38,98±7,57 pg/mL. Ekstrak etanol propolis secara bermakna menurunkan kadar IL-17 serum (75,62±17,64 pg/mL vs 45,59±10,69 pg/mL, p<0,001) dibandingkan dengan kelompok asma. Simpulan, EEP isolat Gunung Lawu menurunkan kadar IL-17 pada hewan coba model asma kronik. [MKB. 2013;45(4):213–7]Kata kunci: Asma, interleukin-17 (IL-17), propolisEthanolic Extract of Propolis Decreases Serum IL-17 Levels in Balb/C Model of Chronic AsthmaInterleukin-17 (IL-17) induces the neutrophil recruitment into the respiratory tract while playing a role in the pathogenesis of asthma and determining the severity of disease. The aim of this study was to analyze the effect of ethanol extract of propolis (EEP) Lawu mountain isolates on IL-17 serum levels in Balb/C mice model with chronic asthma. This study was an experimental research laboratory with 28 male Balb/C mice divided into control, asthma, asthma+EEP and asthma+antihistamine groups. The study was conducted at the Histology and Biomedical Laboratory, Faculty of Medicine, Sebelas Maret University, Surakarta, during April to September 2012. A model of chronic asthma was induced in male Balb/C mice using an intraperitoneally (i.p.) injection ovalbumin (OVA, 100 μg/mice) and aluminum hydroxide (10%, 50 mg/mice) in phosphate-buffered saline (PBS). Experimental animals were sensitized for 6 weeks with inhaled 2% (w/v) OVA aerosol in 0.9% NaCl for 30 minutes/day, 3 days in a week, for asthma, asthma with EEP, and asthma with antihistamine mice model groups. Control mice were not inoculated during the study. Detection of IL-17 serum level was conducted by using enzyme-linked immunosorbent assay (ELISA). One way analysis of variance (ANOVA) for IL-17 serum level and p<0.05 were used to determine significant differences. Serum levels of IL-17 showed 17.15±8.25 pg/mL in control group and 38.98±7.57 pg/mL in antihistamine, respectively. Ethanol extract of propolis showed significant decreased in IL-17 levels (75.62±17.64 pg/mL vs 45.59±10.69 pg/mL, p<0.001) compared to asthma group. In conclusion, EEP Lawu mountain isolates can decrease IL-17 level in chronic asthma animal models. [MKB. 2013;45(4):213–7]Key words: Asthma, interleukin-17 (IL-17), propolis DOI: http://dx.doi.org/10.15395/mkb.v45n4.167
ENGARUH EKSTRAK PATIKAN KEBO (EUPHORBIA HIRTA L.) TERHADAP HITUNG EOSINOFIL DARAH TEPI PADA MENCIT MODEL ASMA ALERGI Heri Prasetyo, Diding; Putranto, R.P. Andri; Martini, Martini; Sarsono, Sarsono
Jurnal Kedokteran YARSI Vol 16, No 3 (2008): SEPTEMBER - DESEMBER 2008
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (147.327 KB) | DOI: 10.33476/jky.v16i3.246

Abstract

Asthma is characterized by both chronic inflammation and remodeling of the airways. Eosinophils may contribute to inflammation associated with bronchial asthma by causing tissue damage and subsequently organ dysfunction, but also by the generation of cytokines and lipid mediators. It was reported in previous studies that pharmacological activities were identified in various compounds extracted fromEuphorbia hirta L. such as antiinflammatory,histamine inhibitor, lipoxygenase inhibitor, anti-allergic and cyclooxygenase inhibitor. This study was aimed to determine the effect of E. hirtaextract onperipheral blood eosinophils count in mice model of allergic asthma. MaleBalb/C mice were sensitized and challenged intraperitoneally (i.p) with ovalbumin(OVA). Mice were immunized i.p. on days 1 and 14 with 2.5 mgof OVA adsorbed to 7.75ml of Aluminium hydroxide gel. OVA challenges (10 mgOVA in l ml of PBS) were administered aerosolly on days 21, 23, 25 and 27, andperipheral blood eosinophilscount was determinedon day 28.A one-way analysis of variance (ANOVA) with LSDpost hocanalysis was used to determine significant differences. Results were expressed as mean+SEM, and values of p 0.05wereconsidered statistically significant. The results showed thatperipheral blood eosinophilscountin the OVA group was51.0+10.4cells/mm E. hirtaextract dose 500 mg/BW/day was30.2+6.3cells/mm3,E. hirtaextract dose 1,000 mg/BW/day was 30.4+6.0cells/mm and antihistamine group was32.2+8.6cells/mm respectively, whilecontrol mice showed46.6-8.8 cells/mm3. It was concluded that E. hirta extract could minimizeperipheralblood eosinophilscount.
KINERJA ANGGOTA KEPOLISIAN REPUBLIK INDONESIA DITINJAU DARI KEPEMIMPINAN, KEDISIPLINAN, DAN KOMPETENSI (STUDI PADA POLRES BOYOLALI) miatmaja, harjanti; Hartono, Sri; Sarsono, Sarsono
Jurnal Edueco Vol. 7 No. 1 (2024): Juni
Publisher : Prodi Pendidikan Ekonomi Universitas Balikpapan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36277/edueco.v7i1.185

Abstract

Studi ini dijalankan dengan maksud agar analisis pengaruh kepemimpinan, kedisiplinan, dan kompetensi pada kinerja Polres Boyolali bisa diketahui. Penelitian kuantitatif adalah metode penelitian yang dipakai dalam studi ini. Purposive sampling dipakai sebagai teknik untuk mengambil sampel dalam studi ini. Observasi, dokumentasi, kuesioner, wawancara, dan studi pustaka adalah sejumlah metode yang dipakai untuk menghimpun data dalam studi ini. Uji regresi linier berganda, uji F, uji t dan koefisien determinasi adalah sejumlah uji yang dipakai peneiti untuk menganalisis data. Hasilnya kepemimpinan mempengaruhi positif signifikan atas kinerja anggota Polres Boyolali. Kedisiplinan mempengaruhi positif signifikan atas kinerja anggota Polres Boyolali. Kompetensi mempengaruhi positif signifikan atas kinerja anggota Polres Boyolali. Hasil uji koefisien determinasi nilai Adjusted 0,415 dan sisanya mendapat pengaruh dari variabel lainnya yang tidak ada dalam studi ini.
Employee Performance at PT Bank Mandiri (Persero) Tbk. Small Medium Enterprise Segment Solo Area Qosim, Nanang; Sarsono, Sarsono; Mursito, Bambang
Journal of Business Innovation and Research Vol 2, No 1 (2023): Journal of Business Innovation and Research
Publisher : UPN Veteran Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31315/jubir.v2i1.9984

Abstract

The Employee Performance reviewed emotional intelligence, style of leadership, organizational commitment and job satisfaction (Study at PT. Bank Mandiri (Persero) Tbk. Small Medium Enterprise Segment in Solo. Thesis for Master of Science Postgraduate Program (M.Si) at Universitas Islam Batik Surakarta 2023. This study aims to determine the effect simultaneously (concurrently) or partial variables of emotional intelligence, leadership style, organizational commitment and job satisfaction on employee performance at PT. Bank Mandiri (Persero) Tbk. Small Medium Enterprise Segment in Solo. This research method used a quantitative research design. The population of all employees working at PT. Bank Mandiri (Persero) Tbk. the Small Medium Enterprise Segment in Solo, with a total of 51 people. The sampling technique used the census technique with a sample of 51 respondents. Data collection was conducted by a questionnaire. The data analysis techniques used statistical analysis, namely multiple linear regression test, F test, t-test, and coefficient of determination. The results showed that emotional intelligence, leadership style, organizational commitment and job satisfaction simultaneously and partially have a positive and significant effect on employee performance at PT. Bank Mandiri (Persero) Tbk., the small-medium enterprise segment in Solo. Suggestions from this study for PT. Bank Mandiri (Persero) Tbk. the Small Medium Enterprise Segment in Solo, continues to improve existing emotional intelligence, leadership style, organizational commitment and job satisfaction thus that it will make employee performance increase and become better than previous.Keyword: employee performances, emotional intelligence, style of leadership, organizational commitment, job satisfaction
LITERASI KEUANGAN MELALUI GEMAR MENABUNG PADA ANAK SEJAK DINI DI SD NEGERI 1 DUWET KELURAHAN DUWET KECAMATAN BAKI KABUPATEN SUKOHARJO Sarsono, Sarsono; Istiqomah, Istiqomah; Kustiyah, Eny; Prasetya, Sosiawan Aji; Rafli, Muhammad; Lestari, Dewi
Bakti Banua : Jurnal Pengabdian Kepada Masyarakat Vol. 4 No. 2 (2023): BAKTI BANUA : JURNAL PENGABDIAN KEPADA MASYARAKAT
Publisher : Sekolah Tinggi Ilmu Manajemen Indonesia (STIMI) Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35130/bbjm.v4i2.501

Abstract

Financial Management is important for managing finances, one of which can be done by saving. Saving must be instilled from an early age. Because savings have an important role in the future. Saving is one way to manage money. The easiest way to save is at home because you can do it any time. SD Negeri 1 Duwet is one of the public elementary schools in Kelurahan Duwet, where the majority of parents work as entrepreneurs, civil servants, and laborers. The children of SDN 1 Duwet City are a little further behind than other public SDs where the parents' lack of interest in education can be seen from the lack of people with a bachelor's degree. Low education has an impact on a lack of understanding in financial management. Community service activities are carried out using the lecture method about the importance of saving, the practice of decorating piggy banks for places to save, giving rewards to children whose piggy banks are best decorated. As a result of this activity the children were very enthusiastic and gave a positive response by listening and competing to decorate their piggy banks, so that it is hoped that the mentality of children who are more thrifty and can spend the pocket money given by their parents wisely and diligently saves
Effect of Cnidoscolus aconitifolius Leaf Extract in Lowering Triglyceride Levels and Body Weight of Wistar Rats with Metabolic Syndrome Sarsanti, Arifa Sherina Noor; Putranto, R. Prihandjojo Andri; Sarsono, Sarsono; Nurwati, Ida; Baihaqy, Fathu Thaariq
Althea Medical Journal Vol 11, No 3 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v11n3.3315

Abstract

Background: Cnidoscolus aconitifolius has the potential to be antidyslipidemic which has the effect of lowering triglyceride levels. This study aimed to explore the effect of Cnidoscolus aconitifolius leaf extract on triglyceride levels and body weight of Wistar rats with metabolic syndrome.Methods: This randomized controlled trial with a pre- and posttest design was conducted in 2021 at the Center for Food and Nutrition Studies, Yogyakarta, Indonesia. Male Wistar rats were subjected into metabolic syndrome state with a high-fat and high-fructose diet (HFHFD) for 21 days, then injected with Streptozotocin (STZ, 45 mg/kg) and Nicotinamide (NA, 110 mg/kg), and designated as positive control group. The intervention group was given 150 mg/kg, 300 mg/kg, and 450 mg/kg dose of leaf extract for 28 days. Triglyceride, glucose, high-density lipoprotein or HDL, and cholesterol were measured before and after intervention, using serum samples taken from the retro-orbital vein and analyzed using an enzymatic colorimetric method. The Wistar weight was measured every week. Data was analyzed by paired T-test and One-way ANOVA with Post-hoc Bonferroni and Games-Howell.Results: There was a significant decrease in triglyceride levels after the intervention (p< 0.005). Interestingly, there was also a significant increase in weight gain in all groups after the intervention (p=0.000), both were dose dependent.Conclusion: Cnidoscolus aconitifolius leaf extract is significantly lowering triglyceride levels in the Wistar rats model. In addition, weight gain has also been observed after intervention. Clinical studies are needed to further explore the potential of Cnidoscolus aconitifolius leaves as anti-dyslipidemia.
PENGARUH KUALITAS PELAYANAN TERHADAP KEPUASAN KONSUMEN SIAP EXPRESS PT. ANGKASA PURA LOGISTIK CABANG SOLO Putra, Alridho Harisma; Aryati, Ida; Sarsono, Sarsono
JURNAL DIMENSI Vol 13, No 2 (2024): JURNAL DIMENSI (JULI 2024)
Publisher : Universitas Riau Kepulauan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33373/dms.v13i2.6085

Abstract

Tujuan penelitian ini adalah mengetahui pengaruh pengaruh kualitas pelayanan terhadap keuasan konsumen SIAP Express PT. Angkasa Pura Logistik Cabang Solo. Penulis menggunakan pendekatan kuantitatif bersifat deskriptif. Penelitian ini dilakukan di SIAP Express PT. Angkasa Pura Logistik Cabang Solo. Populasi dalam penelitian ini adalah konsumen SIAP Express PT. Angkasa Pura Logistik Cabang Solo dengan jumlah konsumen sebanyak 310 orang. Untuk memudahkan perhitungan, penulis membulatkan sampel menjadi 100 responden. Penelitian ini menggunakan teknik purposive sampling. Peneliti menggunakan analisis regresi linier berganda. Hasil dari penelitian ini terdapat pengaruh positif dan signifikan secara simultan variabel bebas yaitu bukti fisik (tangibles), keandalan (reliability), daya tanggap (responsiveness), jaminan (assurance), empati (empathy) secara bersamaan memiliki pengaruh yang signifikan terhadap kepuasan konsumen di SIAP Express PT. Angkasa Pura Logistik. Berdasarkan uji t di peroleh hasil variabel bebas yaitu bukti fisik (tangibles) tidak memiliki pengaruh yang positif dan signifikan sedangkan keandalan (reliability), daya tanggap (responsiveness), jaminan (assurance), empati (empathy) memiliki pengaruh yang positif dan signifikan terhadap kepuasan konsumen di SIAP Express PT. Angkasa Pura Logistik.
PERAN KEPERCAYAAN KONSUMEN DALAM MEMEDIASI ELECTRONIC WORD OF MOUTH, BRAND IMAGE TERHADAP KEPUTUSAN PEMBELIAN PRODUK WARDAH (STUDI PADA GENERASI Z DI SURAKARTA) Istiqomah, Aulia; Sudarwati, Sudarwati; Sarsono, Sarsono
JURNAL DIMENSI Vol 14, No 1 (2025): JURNAL DIMENSI (MARET 2025)
Publisher : Universitas Riau Kepulauan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33373/dms.v14i1.7271

Abstract

Tujuan penelitian ini adalah untuk mengetahui pengaruh kepercayaan konsumen terhadap electronic word of mouth dan brand image terhadap penjualan produk Wardah pada Generasi Z Surakarta. Metode pengumpulan data menggunakan kusioner. Kepopuleran penelitian ini dikaitkan dengan Generasi Z di Surakarta yang mengonsumsi produk Wardah dengan sampel sebanyak 100 responden. Teknik sampel yang digunakan adalah purposive sampling. Analisis data dilakukan dengan menggunakan smartPLS. Hasil penelitian menunjukkan bahwa electronic word of mouth dan brand image memiliki pengaruh yang kecil terhadap keputusan pembelian. Electronic word of mouth dan brand image sama-sama memiliki pengaruh terhadap kepercayaan konsumen. Kepercayaan konsumen mempengaruhi keputusan pembelian. Electronic word of mouth mempengaruhi keputusan pembelian berdasarkan kepercayaan konsumen. Brand image mempengaruhi keputusan pembelian melalui kepercayaan konsumen.
A Conversational Implicature Analysis in the Movie “Bird Box” Directed by Susanne Bier Sarsono, Sarsono; Abdulloh, Abdulloh; Muslim, Ikhwan; Basuki, Slamet; Silaban, Delvina
JELL (Journal of English Language and Literature) STIBA-IEC Jakarta Vol 10 No 01 (2025): JELL STIBA IEC
Publisher : STIBA IEC JAKARTA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37110/jell.v10i01.284

Abstract

The research aims to show the types of conversational implicatures between the main characters in the movie Bird Box and to show the contextual meanings of conversational implicatures between the main characters in the movie Bird Box. To determine the generalized and particularized conversational implicature, the researchers employ a qualitative approach to data analysis. Watching the film for many times and recording any utterances that contain the sort of conversational implicature in a data form is how the research's data are gathered. According to the research findings, conversational implicature is present in 15 utterances. Seven of the fifteen data included generalized conversational implicature, and eight of the fifteen contained particularized conversational implicature. Malorie has four particularized conversational implicature data and seven generalized conversational implicature data. On the other hand, Tom and Jessica have two examples of particularized conversational implicature. The contextual meaning of conversational implicature amongst the main characters is also discovered by the researchers, who discover that while Jessica and Tom frequently speak explicitly in the context, Malorie tends to speak out of it