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All Journal HAYATI Journal of Biosciences Jurnal Sain Veteriner BioWallacea Journal of Biological Research Public Health of Indonesia Jurnal Kesehatan Vokasional Jurnal Ilmu dan Teknologi Kesehatan INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGY Bantenese Jurnal Pengabdian Masyarakat Journal of Nursing and Health (JNH) Akper Yakpermas Banyumas Gema Lingkungan Kesehatan Lansau: Jurnal Ilmu Kefarmasian Molekul: Jurnal Ilmiah Kimia Jurnal Abdi dan Dedikasi kepada Masyarakat Indonesia Jurnal Analis Kesehatan Kendari
Angriani Fusvita
Politeknik Bina Husada Kendari
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Earth & Planetary Sciences Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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Assessement of Candida albicans of the oral mucosa among type-2 diabetes mellitus patients attending Bahteramas Hospital, Southeast Sulawesi Province Firdayanti, Firdayanti; Fusvita, Angriani; Umar, Ani
JURNAL INDONESIA DARI ILMU LABORATORIUM MEDIS DAN TEKNOLOGI Vol 7 No 2 (2025): From Natural Compounds to Disease Mechanisms: An Integrated Research Outlook
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/ijmlst.v7i2.5496

Abstract

Diabetes Mellitus (DM) is a disease characterized by hyperglycemia resulting from either insulin deficiency or insulin resistance. Candida albicans is a fungus generally found on the surface of the mucous membrane, which usually dominates and overgrows among DM patients. This study aims to identify the presence of the C. albicans fungus on the oral mucosa of individuals with Type-2 Diabetes Mellitus at Bahteramas Hospital, Southeast Sulawesi Province, Indonesia. A descriptive study was employed, and a purposive sampling technique was used to select a sample of 62 patients. Swab samples were cultured on Potato Dextrose Agar medium for Gram staining and carbohydrate assimilation tests. The resulting culture was tested using CHROMagarTM Candida (CAC) media. Among the 62 samples, 56 samples were identified to have a convex colony, a cream-color surface, a smooth texture, and a Gram-positive nature. The carbohydrate assimilation test showed that the indicated samples could ferment glucose and maltose, but not lactose and sucrose. Green colonies are formed through CHROMagarTM Candida differential media testing. There are 56 identification results for C. albicans from oral mucosal swab samples from 62 patients with Type-2 Diabetes Mellitus at the Bahteramas Hospital, Southeast Sulawesi Province, yielding six other patients with negative results.
Uji Efektivitas Ekstrak Daun Twandokulo (Kleinhovia hospita Linn) Terhadap pertumbuhan Bakteri Streptococcus mutans ATCC 25175 Penyebab Karies Gigi Nur Awalia Putri Zainal; Ainun ayu yuniar; Angriani Fusvita; Rein Rahmat
Jurnal Analis Kesehatan Kendari Vol. 8 No. 1 (2025): Jurnal Analis Kesehatan Kendari (JAKK) : Vol. 8 (1) Desember 2025)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46356/jakk.v8i1.395

Abstract

leaf is one of the local medicinal plants of Southeast Sulawesi, which has several benefits. One of the benefits of the Kleinhovia hospita Linn plant is as an antibacterial. The purpose of this study was to determine the antibacterial effectiveness of tawandokulo leaf extract (Kleinhovia hospita Linn) on the inhibition zone of Streptcoccus mutans ATCC 25175 bacteria. This research is a laboratory experiment to see the antibacterial effectiveness test of tawandokulo leaf extract (Kleinhovia hospita Linn) against Streptcoccus mutans ATCC 25175 bacteria at various concentrations namely 20%, 40%, 60%, positive control Amoxcilin 0.001%, negative control DMSO. Tawandokulo leaf extract was obtained from maceration extraction using ethanol solvent. This study used the agar well diffusion method, incubated at 37oC for 24 hours and the inhibition was measured using a caliper, with extract samples carried out in triplicate. Based on the antibacterial effectiveness test of Tawandokulo Leaf Extract (Kleinhovia hospita Linn) against Streptcoccus mutans ATCC 25175 bacteria, the inhibition response results were obtained at concentrations of 20%, 40%, and 60%. The results obtained showed that the average diameter of the inhibition zone from the growth of Streptcoccus mutans ATCC 25175 bacteria obtained at 20% concentration had no inhibition zone, 40% concentration had no inhibition zone, 60% concentration had an average inhibition zone of 6,23 mm, positive control had an average inhibition zone of 19,13 mm, and negative control had no inhibition zone.
Platelet to cholesterol ratio of high density lipoprotein cholesterol is associated with diabetes and comorbidity risk Ani Umar; Firdayanti; Heni Umar; Angriani Fusvita; Susanti; Sri Aprilianti Idris
Gema Lingkungan Kesehatan Vol. 24 No. 2 (2026): Gema Lingkungan Kesehatan (on progress)
Publisher : Poltekkes Kemenkes Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36568/gelinkes.v24i2.452

Abstract

This study aims to analyze the relationship between platelet to HDL cholesterol (Platelet to HDL Ratio / PHR) ratio and the presence of type 2 diabetes mellitus, as well as evaluate the ability of PHR as a predictor of comorbidity risk. Multivariate logistic regression analysis was used to estimate the odds ratio (OR) and 95% CI. The discriminatory ability of the model is evaluated with the receiver operating characteristic curve (ROC), with the area under the curve (AUC) used to measure the model's performance. Sensitivity and specificity. This study used a cross-sectional observational design with 220 participants (110 type 2 diabetes patients and 110 non-diabetic controls) from the Southeast Sulawesi Provincial General Hospital. Samples were selected based on inclusion criteria (age 30–70 years, for the diabetes group) and exclusion (such as anemia or use of anticoagulant drugs). Data were collected through clinical examinations (age, BMI, blood pressure, platelet count, HDL). PHR is calculated as the number of platelets (per μL) divided by HDL levels (mg/dL). Statistical analysis was performed using independent t-test, multivariate logistic regression, and ROC curve with SPSS software (p < 0.05). The results showed that PHR was significantly higher in the diabetes group with comorbidities (mean 5.49±2.10) than in healthy individuals (4.25±2.39; p < 0.001). The ROC curve shows an AUC of 0.70 for PHR in predicting comorbidity risk, better than HDL alone (AUC 0.55). This study shows that platelet-to-HDL ratio (PHR) is proven to be a simple and economical potential biomarker for detecting an association with diabetes and predicting the risk of vascular comorbidities. These findings support the use of PHR in routine clinical practice, especially in developing countries such as Indonesia. This research contributes to the strategy for the early prevention of diabetes complications through easily accessible hematological parameters.
Co-Authors Adryan Fristiohady Afdillah, Nia Ainun ayu yuniar Anggraeni Anggraeni Ani Umar Ani Umar Ani Umar Umar Apriyanto Apriyanto Arfan Askrening Asriullah Jabbar Aulya, Muhammad Sultanul Badia, Esti Bobi Anggriawan Elma Winarti Esti Badia Fadhliyah Malik Fauziah, Yulianti Febriyani, Rani Firdayanti Firdayanti Firdayanti Firdayanti, Firdayanti Fitriani Fitriani Halik Hasan, Fonnie E Heni Umar Irdayanti Irdayanti irin aprilin janhar Mubarak Muh. Azdar Setiawan Muhammad Ilyas Y Muhammad Sultan aulya Musdalipah Musdalipah Musdalipah Niluh Eka Ayu Pratiwi Nirwati Rusli Nur Awalia Putri Zainal Nur Saadah Daud Nurhikma Nurul Afdhaliyah Nurdin Rahayu, Dian Yuniar Syanti Rein Rahmat Reni Yunus, Reni Reymon Romsyah Maryam Sahidin Sahidin Sahidin Sernita Sernita Sri Aprilianti Idris Sri Aprilianti Idris Sri Aprilianti Idris Sri Aprilianti Idris Sri Rahayu Sri Yosin Vinola Suci Devianti Ningsih Susanti Susanti Susanti Susanti Susanti Susanti Trees, Trees Wa Fifi WAHYUNI Wijayati, Fitri Yodha, Agung Wibawa Mahatva