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Kandungan Metilparaben Dan Propilparaben Dalam Krim Wajah Yang Beredar Di Wilayah Labuan Kabupaten Pandeglang Neng Nurul Fitri; Nita Rusdiana; La Ode Akbar Rasydy
Jurnal Ilmu Farmasi dan Farmasi Klinik No 1 (2024): JIFFK Special Edition Suppl. 2
Publisher : Universitas Wahid Hasyim Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/jiffk.v2i1.9113

Abstract

Methylparaben and propylparaben are compounds that can be used as antibacterials in cosmetics, one of which is in cream preparations. However, if parabens are used excessively, they can cause side effects in the form of increased estrogen, weight gain, irritation, decreased reproductive health, and premature aging. This study aims to identify and determine the levels of methylparaben and propylparaben contained in face creams circulating in the Labuan Region, Pandeglang Regency using the High Performance Liquid Chromatography method. The mobile phase used was methanol: water (4:6), temperature 25oC, flow rate 1.2 mL/min, wavelength 257 nm using an octadecylsilane (C18) column. The results of the four face cream samples used, the samples with the KW 1 and KW 2 codes were not identified as using the preservative methylparaben, the samples with the KW 3 and KW 4 codes contained methylparaben with levels that were still below the maximum limit set by BPOM, namely 0.4% for single preservative use and 0.8% for mixed preservative use. The average percentage of methylparaben content in KW 3 and KW 4 was 0.21% and 0.20%. Meanwhile, the preservative propylparaben was not identified in samples with the codes KW 1, KW 2, KW 3 and KW 4.
Sosialisasi Manajemen Kesehatan dan Pemeriksaan Kesehatan Gratis pada Peserta Game Mobile legends Rasydy, La Ode Akbar; Patriyah, Siti; Muthmainnah, Siti; Saputra, Teguh Wibowo; Apriyana, Tiara; Anni, Rohimah
Jurnal SOLMA Vol. 14 No. 1 (2025)
Publisher : Universitas Muhammadiyah Prof. DR. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/solma.v14i1.16932

Abstract

Background: Dengan prevalensi gaya hidup sedentari yang meningkat di kalangan pemain game, pentingnya edukasi kesehatan dan pemeriksaan rutin menjadi fokus utama Pengabdian ini bertujuan untuk mengevaluasi efektivitas sosialisasi manajemen kesehatan dan pemeriksaan kesehatan gratis bagi peserta game Mobile Legends dalam acara Pekan Raya Mahasiswa. Metode: Sosialisasi manejemen kesehatan, penyelenggaraan pemeriksaan kesehatan dasar meliputi erat badan, tinggi badan, tekanan darah, rabun mata, frekuensi olahraga dan gangguan-gangguan kesehatan yang dirasakan, kemudian dilanjutkan dengan senam dan evaluasi kegiatan pengabdian. Hasil: Sebanyak 36 peserta game Mobile Legends terlibat dalam kegiatan ini. Hasil penelitian menunjukkan peningkatan kesadaran kesehatan peserta yang menyatakan pemahaman yang lebih baik tentang risiko kesehatan terkait gaya hidup sedentari dan menunjukkan minat untuk mengikuti pemeriksaan kesehatan rutin. Pemeriksaan kesehatan gratis berhasil mengidentifikasi individu dengan faktor risiko yang memerlukan tindak lanjut medis. Kesimpulan: Studi ini merekomendasikan integrasi kegiatan serupa dalam acara e-sports lainnya sebagai strategi pencegahan kesehatan publik dan promosi gaya hidup sehat di kalangan pemain game. Kegiatan ini tidak hanya meningkatkan kesadaran kesehatan tetapi juga mendorong komunitas gaming untuk mengadopsi praktik kesehatan yang lebih baik.
PEMERIKSAAN TEKANAN DARAH GRATIS MENGGUNAKAN TENSI DIGITAL PESERTA RAKERDA PDM KABUPATEN TANGERANG Istiyono, Yogi Priyo; Rohimah, Anni; Ghazali, Ahmad Sulton; Rasydy, La Ode Akbar; Pratiwi, Dina; Sulistyo, Suryo; Kuncoro, Banu; Fhatonah, Nuriyatul
Ekalaya: Jurnal Pengabdian Kepada Masyarakat Indonesia Vol. 2 No. 3 (2023): Ekalaya Journal
Publisher : Nindikayla Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57254/eka.v2i3.93

Abstract

The Muhammadiyah Regional Leadership (Pimpinan Daerah Muhammadiyah or PDM) of Tangerang Regency is committed to improving the welfare of the community in its area. One concrete effort to achieve this goal is by organizing free blood pressure checks using digital blood pressure monitors. This activity aims to provide easily accessible healthcare services to the public and raise awareness about the importance of monitoring blood pressure for maintaining good health. In its implementation, this community service initiative involves experienced medical professionals who conduct blood pressure examinations for participants of the Muhammadiyah Regional Leadership's (PDM) Tangerang Regency event. The examination results are directly communicated to the participants, and they receive information and education about blood pressure and the steps to maintain heart health. Overall, the health examination results, particularly body temperature checks, are very satisfactory, with 100% within the normal range. However, for blood pressure examinations, it was found that 25.37% of the participants had low blood pressure, 32.83% were in the normal range, and 41.84% had high blood pressure. With activities like this, it is hoped that participants can take the necessary preventive actions promptly. Furthermore, free blood pressure checks also serve to educate the community about the importance of a healthy lifestyle and regular health monitoring
REVIEW OF THE USE OF UV-VIS SPECTROPHOTOMETRY IN ANALYSIS ACTIVE COMPOUNDS IN HERBAL PRODUCTS Nurul Azizah; Firda Sahara Nida; Siti Nurdiana; Sheva Firdaus. N; La Ode Akbar Rasydy
International Journal of Social Science, Educational, Economics, Agriculture Research and Technology (IJSET) Vol. 4 No. 9 (2025): AUGUST
Publisher : RADJA PUBLIKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54443/ijset.v4i9.872

Abstract

UV-Visible spectrophotometry (UV-Vis) is one of the most widely used instrumental analytical methods in the fields of pharmacy, food science, and analytical chemistry, particularly for determining the concentration of active compounds in various types of samples. The working principle of UV-Vis spectrophotometry is based on the ability of a compound to absorb light at a specific wavelength, resulting in an absorbance value proportional to the concentration of the substance in solution. This method is considered efficient due to its relatively simple operation, short analysis time, and lower cost compared to other instrumental methods such as HPLC, AAS, or GC-MS. In addition, UV-Vis spectrophotometry can be applied to a wide range of compounds containing chromophoric groups, making it suitable for analyzing herbal products that consist of complex natural matrices. This study aims to review the application of UV-Vis spectrophotometry in the analysis of active compounds in herbal products through a literature review of ten relevant and recent scientific journals. Based on the results of the review, it was found that UV-Vis spectrophotometry is widely used to analyze compounds such as flavonoids, vitamin C, caffeine, paracetamol, and oxalates derived from natural sources such as tea, fruits, vegetables, as well as traditional herbal preparations such as jamu and supplements. In addition, this method is also applied in solubility studies of active compounds within drug delivery systems such as Self-Nanoemulsifying Drug Delivery Systems (SNEDDS), analytical method validation, and evaluation of compound stability in final formulations. Several studies also demonstrated the ability of UV-Vis spectrophotometry to detect the presence of synthetic contaminants in herbal products quickly and simply. From the overall findings, it can be concluded that UV-Vis spectrophotometry plays a significant role in the development, formulation, and quality testing of herbal-based products. This method is not only practical and efficient but also capable of producing reliable quantitative data that can be applied in various research and industrial contexts.
Pemberdayaan Masyarakat Pesisir melalui Pelatihan Pembuatan Permen Ikan untuk Mencegah Stunting Rasydy, La Ode Akbar; Naim, Abu; Zuhro, Siti Fatimatul; Apriyani, Tiara; Saputra, Teguh Wibowo; Budiyanto, Rizki
Jurnal SOLMA Vol. 14 No. 2 (2025)
Publisher : Universitas Muhammadiyah Prof. DR. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/solma.v14i2.18895

Abstract

Background: Desa Karang Serang, yang terletak di pesisir pantai Kecamatan Sukadiri, Kabupaten Tangerang, memiliki banyak potensi berupa sumber daya alam hasil laut, tetapi juga menghadapi banyak masalah kesejahteraan dan kesehatan masyarakat berupa jumlah stunting yang tinggi pada anak-anak yang disebabkan oleh asupan gizi yang tidak seimbang. Pengabdian ini bertujuan untuk memberdayakan masyarakat melalui pelatihan dan pendampingan produksi permen sehat dari ikan di Desa Karang Serang. Metode: Penyuluhan dan pelatihan langsung meliputi sosialisasi stunting dan pembuatan pemen ikan, bimbingan strategi pemasaran produk dan penggunaan media promosi web dan pendampingan halal serta pendampingan produk untuk sertifikat halal sebagai peningkatan nilai mutu jual produk. Kegiatan ini dilakukan pada Mitra UKM Sinar Mutiara yang beranggotakan 10 orang. Hasil: Mitra telah memahami tentang stunting dan meningkatkan softskill cara pembuatan permen dari ikan sebagai sumber penghasilan lokal dan dapat memanfaatkan teknologi digital untuk membantu dalam proses pemasaran produk-produk olahannnya selain itu juga dapat mengetahui tata cara pengajuan setifikasi halal guna dapat meningkatkan nilai kualitas dan harga produk olahannya. Hasil evaluasi menunjukan peningkatan pengetahuan dan keterampilan peserta dari 35% (pre-test) menjadi 100% (post-test). Kesimpulan: Peningkatan pemahaman dan keterampilan mengenai stunting, pembuatan permen serta strategi pemasaran berupa web dan sertifikasi halal telah dapat meningkatkan kesejateraan mitra dan diharapkan mampu menurunkan angka stunting kedepannya.
Characterization and dissolution test of recrystallized mefenamic acid by fast cooling methods Rasydy, La Ode Akbar; Damayanti, Hilda; Satrio, Erza; Supriyanta, Jaka
Pharmaciana Vol. 15 No. 2 (2025): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v15i2.26467

Abstract

Mefenamic acid, classified as a Biopharmaceutics Classification System (BCS) Class II drug, exhibits high permeability but low dissolution rates, limiting its bioavailability. This study aims to enhance the dissolution rate of mefenamic acid through crystal structure modification using fast cooling recrystallization with three distinct solvents: acetone (AMA), ether (AMEt), and ethyl acetate (AME). The recrystallized crystals were characterized using advanced techniques, including polarized microscopy, X-ray Diffraction (XRD), Fourier Transform Infrared (FTIR) spectroscopy, and Differential Scanning Calorimetry (DSC), alongside solubility and dissolution testing. Recrystallization yielded crystals with varied morphologies and sizes, achieving high crystal yields of 92.66% (AMA), 85.54% (AMEt), and 94.59% (AME). FTIR analysis revealed that AME crystals exhibited stronger OH bonding, indicated by the highest peak intensity. XRD diffractograms demonstrated distinct peak patterns at specific 2θ positions for AME crystals, suggesting internal structural changes (polymorphism) while maintaining identical chemical composition. DSC thermograms further confirmed variations in melting points between recrystallized crystals and pure mefenamic acid. Dissolution tests revealed that recrystallized mefenamic acid exhibited significantly improved solubility and dissolution rates compared to its pure form. These findings highlight that rapid cooling recrystallization can produce mefenamic acid polymorphs with optimized dissolution properties, potentially enhancing its pharmacological performance and also provides a promising approach to improving the bioavailability of poorly soluble drugs, offering significant implications for pharmaceutical formulation development.
ANALYSIS OF DANGEROUS DRUG CHEMICALS (BKO) CONTENT IN JAMU USING KCKT: A REVIEW STUDY IN VARIOUS AREAS OF INDONESIA Rochmad Nurchahyo; Amanda Zahira; Aprilia Salwa Maulidina; Elvania Putri; La Ode Akbar Rasydy
International Journal of Social Science, Educational, Economics, Agriculture Research and Technology (IJSET) Vol. 4 No. 5 (2025): APRIL
Publisher : RADJA PUBLIKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54443/ijset.v4i5.942

Abstract

Abstract The rampant abuse of illegal medicinal chemicals (BKOs) in Indonesian traditional herbal medicine has raised serious concerns, with a recent study using HPLC/HPLC analysis on ten studies revealing the content of hazardous substances such as diclofenac sodium (reaching 297,123 mg/L), dexamethasone (exceeding the safe limit), as well as antalgin and sibutramin HCl in several products in circulation. These findings emphasize the need for strict measures, ranging from strict supervision, public education, to legal action, to protect consumers while ensuring herbal medicine remains a safe and sustainable traditional medicine option for future generations.
ANALYSIS OF TANNIN COMPOUNDS IN TURMERIC RHIZOMES (CURCUMA LONGA L.) USING UV-VIS SPECTROPHOTOMETRY Chaerani Chaiis; Lintang Suci Ayu; Celsi andriyani; Siti Mupti Zaenul Inzi; Elvira Atriyani; La Ode Akbar Rasydy
International Journal of Social Science, Educational, Economics, Agriculture Research and Technology (IJSET) Vol. 4 No. 5 (2025): APRIL
Publisher : RADJA PUBLIKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54443/ijset.v4i5.945

Abstract

This study aims to analyze the levels of tannin compounds in fresh and dried turmeric (Curcuma longa L.) rhizomes using the UV-Vis spectrophotometric method. Tannins are phenolic compounds that have important biological activities, such as antioxidant, antimicrobial, and anti-inflammatory. Turmeric rhizome samples were extracted using 96% ethanol solvent by maceration method for three days. Analysis was performed using Folin-Ciocalteu reagent and saturated sodium carbonate solution to form colored complexes measured at a maximum wavelength (λ max) of 706 nm. Quantification was performed by comparing the absorbance results against the gallic acid standard calibration curve, which showed a linear relationship with a coefficient of determination (r²) value of 0.9955. The results showed that fresh turmeric rhizomes had higher tannin levels (57,046 mg GAE/g) than dried turmeric (29,005 mg GAE/g). Qualitative and quantitative analysis showed that the UV-Vis spectrophotometric method was effective for detecting and measuring tannin content accurately and sensitively. In addition, the measurement principle based on the Lambert-Beer law, as well as the use of a spectrophotometer with accurate specifications supports the validity of the results. Literature review from Google Scholar, PubMed, and ScienceDirect of ten supporting journals corroborated that this method has been widely applied for the analysis of phenolic compounds in various natural materials. Thus, This study concluded that turmeric rhizome is a potential source of tannins and the UV-Vis method can be used as a reliable phenolic analysis tool in the pharmaceutical and food fields.
KULIAH KERJA NYATA UNIMAR 2025: IMPLEMENTASI PENGABDIAN MASYARAKAT BERDAMPAK DI KECAMATAN CISOKA, KABUPATEN TANGERANG Anni Rohimah; La Ode Akbar Rasydy; Abu Naim; Yogi Gumilar; Rosidawaty Rosidawaty; Dindin Aminudin; Nurul Setiani; Jaka Supriyanta; Abdul Aziz Setiawan; Dadang Dadang; Fitria Budi Utami; Sena Atmaja
Jurnal Abdi Insani Vol 13 No 1 (2026): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v13i1.2986

Abstract

Fiels Study and Community Service Program is the realization of community service by Unimar students and lecturers in rural community development. Unimar's 2025 Fiels Study and Community Service Program was conducted in four villages in Cisoka District, namely Jeungjing, Cisoka, Caringin, and Bojong Loa. The scope of activities carried out included education, health, social, and religious fields. The objective of Unimar's Fiels Study and Community Service Program activities is to train students' soft skills so they can have a positive impact on the community. The activity was opened by the Regent of Tangerang and the release was carried out by the Cisoka Subdistrict Head. The method used was participatory, involving the community. The programs carried out included education, social, health, MSME empowerment, and simple technological innovations. The output of Fiels Study and Community Service Program was to show an increase in community participation in maintaining environmental health, awareness of stunting prevention, and strengthening collaboration between students and villagers. The Fiels Study and Community Service Program program is a tangible manifestation of campus-community synergy in achieving Sustainable Development Goals (SDGs) 3 (Good Health and Well-being) and 6 (Clean Water and Sanitation). The outcomes of the service program include the availability of supporting facilities for waste management and sanitation.
Analisis Kadar Karboksihemoglobin (COHb) pada Montir Motor di Area Kota Samarinda Rifky Saldi A. Wahid; Georgius Kaperius; La Ode Akbar Rasydy
Jaringan Laboratorium Medis Vol 5 No 2 (2023): November 2023
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jlm.v5i2.10526

Abstract

The quality of air is very important for the environment and human life, however, along with developments in today's increasingly developed and modern era, the quality of the air itself is getting worse and the substances that become air pollutants, one of which is carbon monoxide. Exposure to high amounts of carbon monoxide gas over a continuous exposure period can of course increase carboxyhemoglobin levels in the blood, which will cause health problems. To determine the relationship between carboxyhemoglobin levels in the blood of motor vehicle mechanic workers in the Samarinda city area based on factors such as age, length of work, length of service, and smoking habits. This research used a cross sectional analytical survey design, and sample measurements used the Hindsberg-Lang method which was carried out in May 2023 with a sample size of 17 people and a Spearman rank statistical test was carried out to see whether there was a relationship between variables. 17 motor vehicle mechanics had COHb concentrations that exceeded the normal limit of <3.5%, where the lowest carboxyhemoglobin level was 6.10% and the highest was 9.64%. Correlation data obtained from the p value of age (p=0.000), length of service (p=0.000), time worked (p=0.000), and smoking habits (p=0.004) on COHb levels in the blood of motor vehicle mechanics. The Conclusion: COHb levels in motor vehicle mechanics are above 3.5% and there is a significant relationship between age, length of service, working time and smoking habits on COHb levels in the blood of motor vehicle mechanics.
Co-Authors Abdul Aziz Setiawan Abdul Latif Junaedi Abu Naim Abu Naim Ach. Faruk Alrosyidi Faruk Alrosyidi Alrosyidi Alasya Sihotang Alviolita, Dini Amanda Zahira Anni Rohimah Aprilia Salwa Maulidina Apriyana, Tiara Apriyani, Tiara Ari Yuniarto Ariadin Nurfi Budiyanto, Rizki Celsi andriyani Chaerani Chaiis Dadang Dadang Damayanti, Hilda Devi Ika Lianti Dian Ratih Laksmitawati Dina Pratiwi Dina Pratiwi, Dina Dindin Aminudin Dwi Novita Edi Sumatirta Effionora Anwar Elsa, Restia Elsi Widiarti Elvania Putri Elvira Atriyani Fadila Helma Savira Fhatonah, Nuriyatul Firda Sahara Nida Fitria Budi Utami Georgius Kaperius Ghazali, Ahmad Sulton Ghozali, Ahmad Sulthon Hamidu, La Hendig Winarno Irfan Rusydi Triyanto Jaka Supriyanta Jaka Supriyanta Kuncoro, Banu Kurniasukmawati, Ika Lintang Suci Ayu Megawati, Sefi Mira Eria Anggraini Mohammad Zaky Muhammad Yusuf Hasibuan Muthmainnah, siti Nadila Melva Anggraeni Nasrullah Nasrullah Neng Nurul Fitri Nita Rusdiana Nita Rusdiana S.Farm., M.Sc, Apt Nuraini Nuraini Nuriyatul Fhatonah Nurul Setiani Patriyah, Siti Reza Aditya Sunaryo Rifky Saldi A. Wahid Roby Candra Rochmad Nurchahyo Rohimah Rohimah Rosidawaty Rosidawaty Rulyta Aulia Munandar Sabrina, Anida Adelia Saipullah Pratama Santi Olivia Saputra, Teguh Wibowo Saru Noliqo Rangkuti Satrio, Erza Sena Atmaja Septia Indah Lestari Shella Raudhatul Jannah Sheva Firdaus. N Siti Fatimatul Zuhroh Siti Mupti Zaenul Inzi Siti Nurdiana Soerahman Supriyanta, Jaka Surtiana, Rika Suryo Sulistyo Suryo Sulistyo Syamsudin Syamsudin Sylvia, Diana Tatu Nihayatus Sholehah Sholehah Tresna Ardian Vira Apriliana Widyatari, Ade Dwi wulandari, sisca Yogi Gumilar Yogi Priyo Istiyono Yuniarto, Ari Zenith Putri Dewianti Putri Dewianti Dewianti Zenniah Anggraeni Zein