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All Journal JURNAL GIZI INDONESIA Nurse Media Journal of Nursing Journal of Nutrition College Psikohumaniora: Jurnal Penelitian Psikologi Holistic Nursing and Health Science Medica Hospitalia Dharma Raflesia : Jurnal Ilmiah Pengembangan dan Penerapan IPTEKS Jurnal Penyakit Dalam Indonesia International Journal of Cell and Biomedical Science

Muchlis Achsan Udji Sofro

2Staf Pengajar Bagian Ilmu Penyakit Dalam FK UNDIP/RSUP Dr. Kariadi Semarang

Author-ID : 384564

Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Karakteristik dan Keluaran Pasien COVID-19 dengan DM di RS Umum Pusat Dr. Kariadi (Tinjauan pasien periode Maret-Juli 2020) Minuljo, Tania Tedjo; Anindita, Yohana Prima Ceria; Seno, Heri Nugroho Hario; Pemayun, Tjokorda Gde Dalem; Sofro, Muchlis Achsan Udji
Medica Hospitalia : Journal of Clinical Medicine Vol. 7 No. 1A (2020): Med Hosp
Publisher : RSUP Dr. Kariadi

Pendahuluan Jawa Tengah merupakan propinsi dengan kasus COVID-19 terbanyak ke-4 di Indonesia (lebih dari 8.000 kasus). RS Umum Pusat Dr. Kariadi (RSDK) sebagai RS rujukan memiliki 436 kasus terkonfirmasi COVID-19 per 10 Juli 2020. Diabetes mellitus (DM) diketahui menurunkan sistem imun dan memperburuk reaksi inflamasi. Karakteristik dan keluaran pasien COVID-19 dengan DM di RSDK belum pernah dilaporkan sebelumnya. Metode Data dari rekam medis RSDK. Diagnosis DM: riwayat DM dan/atau GDS >200 mg/dL atau HbA1c >7%. Diagnosis COVID-19: PCR usapan nasofaring-orofaring positif. Karakteristik dasar: usia, jenis kelamin, keluhan, riwayat kontak, riwayat perjalanan, jenis dan tempat perawatan, lama perawatan, komorbid, serta terapi DM. Pemeriksaan penunjang: GDS, HbA1c, kreatinin, saturasi O2, C-reactive protein (CRP), proklasitonin, D-dimer, dan fibrinogen dikelompokkan berdasarkan keluaran (hidup vs. mati); dilakukan uji beda. Analisis dengan SPSS v.24 (IBM, New York, USA). Hasil Pasien COVID-19 dengan DM periode Maret-10 Juli 2020 sebanyak 42 dari total 436 kasus (9,63%). Pria lebih banyak (59,5%). Kasus terbanyak usia >50 tahun (64,3%). Batuk, demam, dan sesak nafas adalah keluhan tersering. Mayoritas pasien menyangkal riwayat kontak ataupun bepergian (>75%). Hampir separuh perlu perawatan intensif sejak awal (40,5%). Komorbid terbanyak hipertensi. Separuh kasus mendapat insulin. Persentase kematian 42,9% (18 dari 42). Rerata kendali glikemik (HbA1c 9,7%) dan saturasi O2 (Sat O2 90%) buruk. Rerata penanda gangguan koagulasi (D-dimer, fibrinogen) dan inflamasi akut (CRP, prokalsitonin) meningkat, berturut-turut 3937,4 ng/mL; 496,1 mg/dL; 16,6 mg/L; 12 ng/mL. Tidak ada beda bermakna antara kelompok hidup dan mati. Kesimpulan Mortalitas dan morbiditas COVID-19 sangat tinggi pada DM. Hampir seluruh pasien mengalami gangguan koagulasi dan inflamasi akut. Kata kunci: COVID-19, DM, RS Kariadi Introduction Central Java province has the 4th largest cases of COVID-19 in Indonesia with more than 8.000 cases. Dr. Kariadi General Hospital (RSDK) is one of the referral hospital with 436 confirmed cases of COVID-19 until July 10th 2020. Diabetes mellitus (DM) known to decreases the immune system and worsens the inflammatory reaction. The characteristics and outcomes of patients with COVID-19 and DM in the RSDK have not been reported yet. Method Data were taken from the RSDK medical record. Diagnosis of DM: history of diabetes and/or RBG >200 mg/dL or HbA1c >7%. Diagnosis of COVID-19 infection: positive PCR from nasopharyngeal-oropharyngeal smear. Baseline characteristics: age, sex, chief complaints, contact and travel history, type and place of care, duration of treatment, comorbidity, and diabetes treatment options. Laboratory result: RBG, HbA1c, creatinine, O2 saturation, C-reactive protein (CRP), proclasitonin, D-dimers, and fibrinogen were grouped according to patient output (life vs. death) and different tests was performed. Data analysis was performed with SPSS v.24 (IBM, New York, USA). Result The number of patients with COVID-19 and DM was 42 out of 436 cases (9.63%). Men was more prevalent (59.5%). Most cases were >50 years of age (64.3%). Cough, fever, and shortness of breath were the most prevalent chief complaints. The majority of patients denied contact or travel history (>75%). Nearly half of the cases needed intensive care (40.5%) at arrival. Hypertension was the no.1 comorbid. Half cases received insulin therapy. Percentage of death was 42.9% (18 out of 42). Average of glycemic control (HbA1c 9.7%) and O2 saturation (Sat O2 90%) were poor. Coagulation (D-dimer, fibrinogen) and acute inflammatory (CRP, procalsitonin) markers were increased, respectively 3937.4 ng/mL; 496.1 mg/dL; 16.6 mg/L; 12 ng/mL. There was no significant difference between the life and death groups. Conclusion Mortality and morbidity of patients with COVID-19 and DM was very high. Almost all patients suffered from disseminated intravascular coagulation (DIC) and severe acute inflammation. Key words: COVID-19, DM, Kariadi Hospital

Korelasi Antara Jumlah Cd4 Dengan Global Longitudinal Strain Ventrikel Kiri Pada Penderita Human Immunodeficiency Virus Pratama, Yanuar Surya; Chairunnisa, Andita; Bahrudin, Udin; Uddin, Ilham; Nugroho, Mochamad Arif; Sofro, Muchlis Achsan Udji; Kristina, Tri Nur
Medica Hospitalia : Journal of Clinical Medicine Vol. 8 No. 1 (2021): Med Hosp
Publisher : RSUP Dr. Kariadi

Latar Belakang: Jumlah CD4 merupakan parameter penting pada penderita HIV dan berhubungan dengan peningkatan risiko disfungsi sistolik. Hingga saat ini, korelasi antara jumlah CD4 dengan parameter global longitudinal strain (GLS) sebagai indikator fungsi sistolik subklinis masih belum jelas. Metode: Penelitian ini merupakan studi observasional dengan metode belah lintang. GLS ventrikel kiri diperiksa menggunakan ekokardiografi dua dimensi. Jumlah CD4 baseline dan nadir diperoleh dari rekam medis sedangkan jumlah CD4 aktual dan CD4 percentage (CD4%) diperiksa menggunakan metode flow cytometry. Hasil: Total 37 pasien HIV asimptomatik mengikuti penelitian dengan rerata umur 31,95± 7,54 tahun dan median durasi penggunaan ARV adalah 34 bulan. Median CD4 baseline dan CD4 nadir adalah 272 sel/uL dan 223 sel/uL, sedangkan rerata CD4 aktual dan CD4% adalah 516,08±252,03 sel/uL dan 19,66±7,97 %. Semua subyek penelitian memiliki fungsi sistolik normal. Rerata GLS ventrikel kiri adalah 17,02±0,71. GLS ventrikel kiri berkorelasi positif dengan CD4 aktual (r=0,43; p=0,008) dan CD4% (r=0,349; p=0,034). Penderita HIV dengan jumlah CD4 aktual ?400 sel/uL memiliki GLS ventrikel kiri yang lebih baik dibandingkan dengan yang <400 sel/uL (p=0,022). Kesimpulan: Jumlah CD4, terutama CD4 aktual dan CD4 percentage berkorelasi dengan disfungsi sistolik subklinis yang diukur dengan global longitudinal strain pada penderita HIV asimtomatik. Hal ini mungkin dapat menjelaskan peran CD4 terhadap patogenesis gagal jantung pada penderita HIV.

Peer Education with Smart Card Effects on the Stigma of HIV/AIDS among Non-HIV Inmates Anisah, Retno Lusmiati; Andriany, Megah; Sofro, Muchlis Achsan Udji; Piriyasart, Jitlada
Holistic Nursing and Health Science Vol 7, No 1 (2024): June
Publisher : Master of Nursing, Faculty of Medicine, Universitas Diponegoro, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/hnhs.7.1.2024.30-39

Inmates with HIV/acquired immunodeficiency syndrome (AIDS) are often exposed to psychosocial problems due to stigma. Limited study proved effect of peer education with smart card on the stigma of HIV/AIDS among non-HIV inmates. The purpose of this study was to know the effects of peer education with smart card method on the stigma of HIV/AIDS among inmates. The study design was pre-experimental design. The sample was 94 male inmates without HIV taken using purposive sampling. The stigma was measured used the Visser Personal and Perceived Community Stigma questionnaire. Non-HIV prisoners was educated regarding using HIV/AIDS Smart Cards, Anti-HIV/AIDS Stigma and Discrimination Cards as well as involving a positive HIV for hand shaking role play. Data were analyzed using the Wilcoxon signed rank test. The results showed significant differences between the pre and post-test on personal and perceived community stigma. The findings recommend for correctional nurses to imply this intervention in preventing the stigma of HIV/AIDS and future studies to examine this intervention toward other outcomes such as discrimination in correctional settings.

A social support for housewives with HIV/AIDS through a peer support group Sofro, Muchlis Achsan Udji; Hidayanti, Ema
Psikohumaniora: Jurnal Penelitian Psikologi Vol. 4 No. 1 (2019)
Publisher : Faculty of Psychology and Health - Universitas Islam Negeri Walisongo Semarang

Housewives with HIV/AIDS are faced with internal problems because the virus continues to invade their bodies and external problems such as caring for their husbands and children infected with HIV/AIDS, stigma and discrimination, maintaining family integrity and even taking responsibility for economic problems when the husband dies. They need social support. One of the most important sources of social support is peers, especially for those who have not done open status to the family. Peer support can be obtained through Peer Support Groups (KDS) through counseling, education, and information. This qualitative research using the methodology approach tries to explore the social support that is obtained by housewives with HIV/AIDS through peer support groups that they participate in General Hospital Dr. Kariadi Semarang. Research involving 15 informants shows that peer support groups can provide social support for them, including information support about the treatment and development of HIV/AIDS; emotional support, self-esteem support, and network support such as intensive communication and strong friendships; and real assistance: venture capital assistance, business skills, and assistance in accessing treatment

Factors Influencing the Barriers to Performing Five Daily Prayers among Muslim Inpatients at RSUP Dr. Kariadi Sofro, Muchlis Achsan Udji; Ardani, Yanuar; Sammy, Alwi
International Journal of Cell and Biomedical Science Vol 3 No 7 (2024)
Publisher : Stem Cell and Cancer Research (SCCR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59278/cbs.v3i7.45

Background: Prayer is a fundamental obligation for Muslims, performed five times daily. For hospitalized Muslim patients, maintaining regular prayer routines can be challenging due to physical limitations, hospital infrastructure barriers, lack of religious knowledge, and insufficient support from healthcare providers. Objective: This study aims to identify the barriers Muslim inpatients face in performing prayers and to propose recommendations for improving spiritual accommodations in hospital settings.Methods: A qualitative study was conducted at RSUP Dr. Kariadi using in-depth interviews and participatory observation. Thirty Muslim inpatients, along with family members and medical personnel, were involved. Data were collected through semi-structured interviews and direct observations, then analyzed using thematic analysis to identify major influencing factors.Results: Physical limitations such as pain (40%), difficulty standing (50%), and movement restrictions from medical devices (33.3%) were key barriers. Facility-related issues, including inaccessible prayer rooms (70%) and lack of prayer aids (55%), significantly impacted patients' ability to pray. Religious knowledge gaps were notable, with 60% of patients unaware of permissible prayer adjustments (rukhsah). Furthermore, 80% reported no assistance from healthcare staff in facilitating prayer. Psychological factors such as stress (30%) and fatigue (25%) also affected patients' motivation, while encouragement from family and staff (50%) positively influenced prayer practices. Conclusion: Muslim inpatients encounter multiple barriers to performing prayers during hospitalization. Structured interventions, including improving hospital facilities, providing religious education, and training healthcare providers in spiritual care, are essential to support the spiritual well-being of Muslim patients.

REKOMENDASI STRATEGI PENGENDALIAN DENGUE DI KOTA BENGKULU TAHUN 2023-2025: FOCUS GROUP DISCUSSION (FGD) Triana, Dessy; Gunasari, Lala Foresta Valentine; Martini, Martini; Suwondo, Ari; Sofro, Muchlis Achsan Udji
DHARMA RAFLESIA Vol 23 No 1 (2025): JUNI (ACCREDITED SINTA 5)
Publisher : Universitas Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/dr.v23i1.39717

Dengue is a global health problem. There has been an increase in cases of more than 15 times over the last two decades. The causes of the rise in the number of cases and the increase in infected areas are very complex and multifactorial, including viral, vector, environmental, and human factors. A comprehensive prevention strategy is needed that includes all component factors that influence dengue disease to predict the incidence of the disease. This activity aimed to implement effective dengue control in Bengkulu City to reduce the number of dengue cases. The activity partners were the Bengkulu City Health Service, Bengkulu Provincial Health Service, Community Health Centers in Bengkulu City, and surveillance officers. The method of this activity was to focus group discussion to formulate a dengue control strategy in Bengkulu City for 2023-2025. The dengue control strategy that has been formulated can be implemented in the work area of the community health center to reduce the number of dengue cases.

Co-Authors Alifiati Fitrikasari Anak Agung Gede Sugianthara Anindita, Yohana Prima Ceria Anisah, Retno Lusmiati Anjani, Gemala Ardani, Yanuar Ari Suwondo Ariani Ariani Arifah, Meika Rahmawati Chairunnisa, Andita Darmono Dessy Triana Ema Hidayanti Franzeska Anna Dewi Mursita Widinartasari, Franzeska Anna Dewi Mursita Gede Arya Bagus Arisudhana Gunasari, Lala Foresta Valentine Haidati, Titis Hari Peni Julianti Hindaryani, Nurul Ilham Uddin Innawati Jusup Joyeti Darni K. Heri Nugroho HS, K. Heri Kis Djamiatun Kusmiyati Tjahjono Linda Kartika Sari Martini Martini Megah Andriany Minuljo, Tania Tedjo Mochamad Arif Nugroho Mohammad Sulchan Muflihatunnaimah, Muflihatunnaimah Muhammad Ali Sodiq, Muhammad Ali Peni, Hari Piriyasart, Jitlada Pratama, Yanuar Surya Raharja, Tommy S.S, Darmono Salahudin, Muhammad Ismail Sammy, Alwi Suparno Suparno Tjokorda Gde Dalem Pemayun Tri Nur Kristina Tri Winarni Agustini Udin Bahrudin, Udin Untung Sujianto Wicaksono, Yamaji Adi Widiastuti, Yuliati

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