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All Journal Medicina E-Jurnal Medika Udayana Jurnal Veteriner e-CliniC Medical Journal of Indonesia The Indonesian Biomedical Journal JBN (Jurnal Bedah Nasional) ISM (Intisari Sains Medis) : Jurnal Kedokteran Majalah Patologi Indonesia Jurnal Respirasi (JR) Neurologico Spinale Medico Chirurgico Jurnal Kedokteran Universitas Palangka Raya Indonesian Journal of Cancer Journal of Global Pharma Technology
Ni Putu Sriwidyani
Departemen Patologi Anatomi Fakultas Kedokteran Universitas Udayana
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health Veterinary

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Journal : Medicina

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THE CHARACTERISTIC OF CYTOLOGICAL AND PCR TESTS RESULT OF FINE NEEDLE ASPIRATION (FNA) SPECIMEN FROM NECK LYMPH NODE/S ENLARGEMENT CLINICALLY DIAGNOSED AS TUBERCULOUS LYMPH ADENITIS Winarti, Ni Wayan; Sriwidyani, Ni Putu
Medicina Vol 43 No 3 (2012): September 2012
Publisher : Medicina

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Abstract

Diagnosis of Tuberculous (TB) lymph adenitis is still problematic due to paucibacillar. Since histopathological biopsy examination is relatively expensive and needs times, FNA is being more frequently chosen. The specimen from FNA can be processed for cytological and PCR tests, but there is no data available describe the characteristic of the result of both methods. Hence, study is needed in order to improve knowledge and health services. A cross sectional study had been conducted from January 1st   until December 31st   , 2011, at Anatomical Pathology Laboratory of Medical School of Udayana University/Sanglah Hospital and Biomolecular Laboratory of Medical School of Udayana University. The subjects were all patients with clinical diagnosis TB lymph adenitis who met the eligibility criteria. During 6 months, there were 46 patients included in the study. They were 65% female and 35% male. The age was ranging from 5 years old until 83 years old and 30-39 years old age group was the highest in number (39%). Positive cytology result was found in 22 cases (48%), while PCR test revealed no positive result. There was significant diference between positive and negative cytology test in pain sensation category, conversely in onset, number of enlarged lymph node/s, localization, conglomeration and fixation categories. If every single clinical character was marked with score 1, node/s with accumulative scores 4-6 showed no different cytology result with node/s with score 1-3. This study shows that in detecting TB lymph adenitis using FNA specimen, cytology test was be#er than PCR
MUTASI K RAS PADA KARSINOGENESIS KANKER KOLOREKTAL Sriwidyani, Ni Putu
Medicina Vol 44 No 2 (2013): Mei 2013
Publisher : Medicina

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Karsinogenesis kanker kolorektal merupakan proses multi-step, melibatkan berbagai abnormalitasgenetik. Mutasi gen K RAS sering ditemukan pada tumor ini. K RAS adalah gen yang menyandi proteinK ras, suatu produk proto-onkogen yang merupakan komponen penting pada jalur pensignalan darireseptor permukaan sel untuk mengontrol proliferasi, diferensiasi, dan kematian sel. Kebanyakanmutasi terjadi pada kodon 12 dan 13 dari ekson 1. Protein K ras mutan akan menyebabkan aktivasipersisten dari banyak signal downstream dari pertumbuhan dan survival sel. Pemeriksaan adanyamutasi pada gen K RAS memegang peranan penting pada prognosis dan terapi dari kanker kolorektal.[MEDICINA 2013;44:97-100].
Co-Authors Anak Agung Ayu Ngurah Susraini Angelia Ongko Prabowo annie minerva datui Astuti, Ida Ayu Jelantik Bintang Dwi Oktaviani Cahyani, Kadek Cindy Dwi Citra, Dandy Damayanti, Ni Kadek Ayu Maya Desak Made Cittarasmi Saraswati Seputra Dewi, Ida Ayu Krisna Cantika Dewi, Ida Ayu Meilasari Dewi, Ni Putu Wulan Tantri Diahningrum, Sylvi Handoko, Jovi Carina Henky, . Herlina Eka Shinta Herman Saputra Herman Saputra Herman Saputra Herman Saputra Herman Saputra Herman Saputra Herman Saputra I Dewa Ayu Inten Primayanti I Gde Raka Widiana I Gede Indradika Pratama Putra I Gusti Ayu Dewi Ratnayanti I Gusti Ayu Sri Mahendra Dewi I Gusti Kamasan I Gusti Kamasan Arijana I Gusti Kamasan Nyoman Arijana I Gusti Ngurah Kade Mahardika I Gusti Ngurah Made Cesar Vajrashrava Sunantara I Gusti Ngurah Mayun I Gusti Ngurah Pratama Yuda Atmaja I Gusti Nyoman Sri Wiryawan I Kadek Yana Parastuta I Ketut Bawantika Adi Putra I Made Gotra I Made Jawi I Made Muliarta I MADE MULIARTA . I W. Sudarsa I Wayan Juli Sumadi I Wayan Niryana I Wayan Putu Sutirta Yasa I Wayan Sugiritama Ida Ayu Jasminarti Dwi Kusumawardani Ida Ayu, Priandini Iin Indrayani Maker, Luh Putu Ivana Juliarty Sitanggang Kadek Dwi Pradnyawati Kandy Rosa Ismalia Katrin Rotua Simbolon Ketut Mulyadi Komang Chandra Surya Dika Limantoro, Joshua Lisanthoni, Johnathan Luh Ayu Widayanti Luh Ayu Widayanti Luh Komang Ayu Widhiaty Karang Luh Putu Iin Indrayani Maker Luh Yeni Laksmini M. Arif Perdana Ariyansyah Made Agus Cahya Nugraha Koriawan Maker, Luh Putu Iin Indrayani Manuaba, Ida Bagus Tjakra Wibawa Moestikaningsih . Nariswari, Ida Ayu Ista Nathaniela, Jocelin Ni Gusti Ayu Agung Manik Yuniawaty Wetan Ni Kadek Ayu Maya Damayanti Ni Luh Gede Yoni Komalasari, Ni Luh Gede Yoni Ni Made Adi Tarini Ni Made Mahastuti Ni Putu Ekawati Ni Wayan Candrawati Ni Wayan Winarti Nornazirah Binti Azizan Popi Imelda Margareth Sitompul Pramitasuri, Tjokorda Istri Putra, Putu Krishna B. S. Putri, Kadek Sri Adi Putu Ayu Widya Pramesti Putu Erika Paskarani Putu Febry Krisna Pertiwi Putu Julia Chandra Devi Raka-Sudewi A. A. Sang Ayu Putu Yuliantini Setiawan, I Gede Budhi Silvia Nuhyil Indriani Sinaga, Naomi Juliana Sri Mahendra Dewi, I Gusti Ayu Suastini, Kadek Denik Sumadi, I Wayan J. Suryawisesa, Ida Bagus Made Susilawathi, Ni Made tanaka, Tanaka Tjandra Kristiana Volman Tampubolon Wetan, Ni Gusti Ayu Agung Manik Yuniawaty Wilananda, Ida Bagus Ardya Kurnia Wimpie I Pangkahila Winari, Ni Wayan Yasa, I Nyoman Wawan Tirtha