Article Per Year (5 Year)
p-Index From 2020 - 2025
2.554
P-Index
This Author published in this journals
All Journal Jurnal Gizi dan Pangan Jurnal Gizi Jurnal Kesehatan Masyarakat Indonesia MEDIA MEDIKA INDONESIANA Journal of Nutrition and Health JURNAL GIZI INDONESIA Journal of Nutrition College Sari Pediatri Universa Medicina Health Notions Jurnal Ilmu Kefarmasian Indonesia Medica Hospitalia Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia World Nutrition Journal IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) Berita Kedokteran Masyarakat
Hertanto Wahyu Subagio
Clinical Nutrition Department, Medical Faculty, Diponegoro University
Biochemistry, Genetics & Molecular Biology Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

Published : 41 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 41 Documents
Search

 1   2   3   4   5 
HUBUNGAN DERAJAT KEPARAHAN STROKE DENGAN PERUBAHAN STATUS GIZI PASIEN DI UNIT STROKE Camelia Bomaztika Sari; Hertanto Wahyu Subagio; Etisa Adi Murbawani
IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN Vol 3 No 1 (2020): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN)
Publisher : Perhimpunan Dokter Gizi Klinik Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54773/ijcnp.v3i1.20

Abstract

Latar belakang : Defisit neurologis akibat stroke akut menyebabkan perburukan malnutrisi selama perawatan di rumah sakit dan dikaitkan dengan outcome klinis lebih buruk, masa rawat lebih lama dan biaya lebih besar. Tujuan: Menganalisis hubungan derajat keparahan stroke dengan perubahan status gizi pasien selama pelayanan di Unit Stroke dan faktor-faktor yang mempengaruhinya. Metode : Penelitian cross-sectional dilakukan di Unit Stroke RSUP dr. Kariadi Semarang pada bulan Maret - Mei 2019 terhadap 60 subyek pasien stroke yang dipilih secara consecutive sampling serta memenuhi kriteria inklusi dan eksklusi. Penilaian NIHSS dilakukan pada awal dan akhir pengamatan; pengukuran dan perubahan LLA pada hari ke-1, ke-3, ke-7, ke-14; status diare serta status disfagia. Uji Chi-square dilakukan untuk melihat hubungan antara derajat keparahan stroke dengan faktor-faktor yang berhubungan dengan perubahan status gizi pasien. Hasil: Derajat keparahan stroke sedang dan berat lebih banyak dijumpai. Target pemenuhan energi hari ke-5 dapat dicapai 80% subyek, penurunan LLA 35%, diare 11,7% dan disfagia 46,7%. Terdapat hubungan signifikan antara derajat keparahan stroke dengan perubahan LLA (p < 0,05). Simpulan : Derajat keparahan stroke berhubungan dengan perubahan status gizi selama perawatan yang dinilai dari penurunan LLA.
HUBUNGAN ANTARA ANGKA KECUKUPAN ENERGI DAN PROTEIN DENGAN KESEMBUHAN LUKA PADA PASIEN ULKUS DEKUBITUS Nathalia Safitri; Hertanto Wahyu Subagio; Etisa Adi Murbawani; Niken Puruhita; Amalia Sukmadianti
IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN Vol 4 No 2 (2021): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN)
Publisher : Perhimpunan Dokter Gizi Klinik Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54773/ijcnp.v4i2.76

Abstract

ABSTRAK Latar belakang : Ulkus dekubitus merupakan masalah kesehatan di banyak negara dan malnutrisi merupakan salah satu faktor yang berpengaruh dalam perkembangan ulkus dekubitus, namun investigasi klinis masih jarang dilakukan untuk mengamati kebutuhan jumlah energi dan protein pada kesembuhan luka. Tujuan penelitian : Menganalisis hubungan antara angka kecukupan energi dan protein dengan kesembuhan luka pada pasien ulkus dekubitus. Menganalisis hubungan antara angka kecukupan energi dan protein dengan kesembuhan luka pada pasien ulkus dekubitus dikontrol dengan faktor usia, indeks massa tubuh, dan adanya infeksi. Metode penelitian : Studi observasional dengan pendekatan cross sectional melibatkan 40 subjek sesuai kriteria inklusi dan eksklusi. Kesembuhan luka dinilai menggunakan PUSH score tools 3.0, angka kecukupan energi dan angka kecukupan protein dinilai berdasarkan rata-rata asupan total masing-masing yang diberikan dalam seminggu. Hasil : Terdapat hubungan lemah antara angka kecukupan energi dengan kesembuhan luka (r= 0,37 dan p= 0,02). Adanya hubungan sedang antara angka kecukupan protein dengan kesembuhan luka (r= 0,42 dan p= 0,01). Simpulan : Terdapat hubungan bermakna antara angka kecukupan energi dan protein dengan kesembuhan luka pada pasien ulkus dekubitus. Faktor usia, indeks massa tubuh, dan infeksi pada ulkus dekubitus bukan merupakan variabel perancu dalam penelitian ini. Kata kunci : Angka kecukupan energi, angka kecukupan protein, kesembuhan luka, ulkus dekubitus.
FAKTOR YANG BERHUBUNGAN DENGAN KEJADIAN DIARE DI UNIT STROKE RSUP DR. KARIADI: diare Taufik Hilmansyah; Hertanto Wahyu Subagio; Annta Kern
IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN Vol 5 No 1 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN)
Publisher : Perhimpunan Dokter Gizi Klinik Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54773/ijcnp.v5i1.85

Abstract

Abstrak Latar belakang: Diare disebabkan oleh multifaktorial dan beberapa faktor diketahui berhubungan dengan diare selama pasien dirawat yaitu usia lanjut, lama rawat inap, kejadian infeksi, penggunaan antibiotik, dan status gizi malnutrisi. Di RSUP Dr. Kariadi Semarang belum pernah dilakukan penelitian faktor yang berhubungan dengan diare. Tujuan: Menghitung besar risiko usia lanjut, lama rawat inap, kejadian infeksi, penggunaan antibiotik, formula nutrisi enteral non pabrikasi, dan status gizi malnutrisi dengan kejadian diare. Metoda: Jenis penelitian case control dengan mengambil data restrospektif pasien stroke yang memenuhi kriteria inklusi dan eksklusi selama Januari – April 2020. Dilakukan pemeriksaan data berdasarkan variabel bebas, dilakukan pencatatan dan dianalisis hubungan dengan menggunakan uji statistik Chi Square. Hasil: Sebanyak 40 subyek penelitian yang di rawat di unit stroke RSUP Dr Kariadi mayoritas diagnosis stroke non hemoragik (55%) dan laki-laki (60%). Mayoritas subyek usia non geriatri yaitu kurang dari 60 tahun. Hasil penelitian menunjukkan adanya hubungan yang signifikan pada faktor usia lanjut, lama rawat inap dan penggunaan antibiotik terhadap diare. Usia lanjut subyek (p = 0,043) dengan risiko 10 kali lipat. Lama rawat inap > 5 hari (p = 0,031) dengan risiko 11,56 kali lipat. Penggunaan antibiotik dengan risiko 13,5 kali lipat. Sedangkan variabel lain tidak signifikan. Simpulan: Terdapat hubungan usia lanjut, lama rawat inap >5 hari dan penggunaan antibiotik terhadap kejadian diare pada pasien stroke yang di rawat di unit stroke RSUP Dr Kariadi Kata kunci: diare, unit stroke, geriatri, antibiotik, lama rawat inap
Ekspresi VEGF Sel Adenokarsinoma Mamma Pada Pemberian Oral Ekstrak Andrographis paniculata NUGRAHANINGSIH NUGRAHANINGSIH; SARJADI SARJADI; EDI DHARMANA; HERTANTO WAHYU SUBAGIO
JURNAL ILMU KEFARMASIAN INDONESIA Vol 13 No 1 (2015): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (234.677 KB)

Abstract

Angiogenesis was needed to fulfill nutrition and oxygen demand for tumor growthh and its metastase. Vascular endothelial growth factor (VEGF) was a potential proangiogenic factor of angiogenesis process. In vitro study of Andrographis paniculata extract showed decreasing tend of VEGF level serum on PC-3 cancer cell line. The aim of this study was to prove the effect of oral administered Andrographis paniculata extract on VEGF expression of adenocarcinoma mammae C3H mice. Twenty four mice was transplanted with adenocarcinoma mammae randomly to four groups. Andrographis paniculata extract at dose 5, 10, and 15 mg/day were given on mice group along 14 days. One group another as a control. VEGF expression were examined use immunohistochemistry staining. Anova test showed difference VEGF expression among reseach groups (p=0,000, r=-0,953). The highest of VEGF expression index 24,8 was found on control group, and the lowest 19,4 was found on group which received 15 mg/day. We concluded that oral administration of Andrographis paniculata extract decreased VEGF expression of adenocarcinoma mamme C3H mice.
Correlation of dietary intake and physical activity with nutritional status, body composition and hand grip strength in elderly Etisa Adi Murbawani; Hertanto Wahyu Subagio; Niken Puruhita; Enny Probosari; Aryu Candra
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 10, No 1 (2021): December
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jgi.10.1.21-27

Abstract

ABSTRACT               Background: Increased life expectancy has both positive and negative impacts. Elderly group are prone to nutritional issues and body function disorder such as sarcopenia. Factors including dietary intake and physical activity are contributors of sarcopenia.Objectives: The purpose of this study is to analyze the correlation of dietary intake and physical activity with nutritional status, body composition and hand grip strength (HGS) in elderly.Materials and Methods: The study was held on July-October 2020 at the Panti Wredha Dharma Bakti Surakarta. This was a cross-sectional study of 54 elderly subjects. Subjects were selected by purposive sampling method. The data included height was measured using microtoise, while weight and body composition was measured using Bioelectrical Impedance Analyzer (BIA). Dietary intake was obtained through comstock observation. Physical activity was measured by the International Physical Activity Questionnaire. Hand grip strength values was measured by hand grip dynamometer. Data normality analyzed by Kolmogorov-Smirnov test. Bivariate test analyzed by Rank Spearman test.Results: Energy, carbohydrate and fat intake had no correlation with nutritional status, total body fat percentage, subcutaneous fat percentage and skeletal muscle mass percentage (p value > 0.05), but there was a relationship between energy (p value = 0.33), carbohydrate (p value = 0.016) and fat intake (p value = 0.047) with visceral fat percentage. Physical activity had relation with nutritional status (p = 0.048) but had no relationship with total body fat percentage, visceral fat percentage, subcutaneous fat percentage and skeletal muscle mass percentage. Protein intake also had no relationship with HGS value (p value> 0.05).Conclusions: Dietary intake only correlated with visceral fat percentage, but had no correlation with other body composition parameters. Physical activity correlated with nutritional status, but had no correlation with all of body composition parameters. Protein intake also had no correlation with HGS.
KECEPATAN PENCAPAIAN TARGET ENERGI DAN PROTEIN SERTA HUBUNGANNYA DENGAN PENURUNAN INDEKS MASSA TUBUH DAN LINGKAR LENGAN ATAS PADA PASIEN STROKE Joriandhita Ramadhan; Hertanto Wahyu Subagio; Enny Probosari
IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN Vol 5 No 1 (2022): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN)
Publisher : Perhimpunan Dokter Gizi Klinik Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54773/ijcnp.v5i1.84

Abstract

Background: Some anthropometrics assessment on risk of malnutrition are by measuring the mid-arm circumference (MAC) and calculating the body mass index (BMI). Objective: To analyze the relationship between days of energy and protein target achievement to the reduction of MAC and BMI in stroke patients in Indonesia. Method: The study design was an observational study with a cross-sectional approach to determine the relationship between days of energy and protein target achievement to the reduction of MAC and BMI. A total of 55 subjects who met the inclusion and exclusion criteria were taken at the Stroke Unit of RSUP Dr. Kariadi Semarang during January-March 2021. MAC measurements and BMI calculations were carried out. Analysis of the relationship between dependent and independent variables using the chi square statistical test. Results: Most of the subjects achieved their energy and protein targets within ≤ 3 days. Days of energy and protein target achievement did not correlate with the reduction in MAC and BMI statistically (p> 0.05), but the research data stated that as a percentage, one third of the subjects who reached the energy and protein targets ≤ 3 days did not experience reduction. Conclusion: All subjects were stroke patients aged 19-59 years where 49 (89,1%) could meet their energy and protein targets within ≤ 3 days and 17 (34,7%) subjects did not experience reduction in MAC and BMI. Keywords: Stroke, MAC, BMI, malnutrition, anthropometry
Status besi, seng dan vitamin A pada kehamilan Hertanto Wahyu Subagio
Berita Kedokteran Masyarakat (BKM) Vol 21, No 4 (2005)
Publisher : Fakultas Kedokteran Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/bkm.3665

Abstract

Introduction: Micronutrients problems in pregnancy gain less attention than iron deficiency. This study was aimed to describe iron, zinc and vitamin A status and their changes during second and third trimester of pregnancy. Methods: Serum transferrin receptor (sTfR) as measurement for iron status, zinc level and retinol were obtained from serum of 70 pregnant women who were purposively chosen. The measurements were conducted in the second and third trimester. The changes of micronutrients level were analyzed using paired t-test Results: The prevalence of anemia in the second and third trimester was 77,1% and 64,3% respectively. Only 31,4% of subjects had iron deficiency, while zinc and vitamin A deficiency occurred in 64,7% and 11,4% of the subjects respectively. The level of the micronutrients significantly changed during the third semester of pregnancy. The prevalence of iron deficiency in the third trimester decreased to 17,1%. All subjects had zinc deficiency while vitamin A deficiency was observed in 25,7% of the pregnant women Conclusion: The prevalence of zinc and vitamin A deficiency is high, as well as iron deficiency. There is an increase in iron status from second to third trimester of pregnancy. Conversely, zinc and vitamin A status decrease significantly. Keywords: anemia micronutrient pregnancy
HUBUNGAN PHASE ANGLE DENGAN TINGKAT KEPARAHAN INFARK MIOKARD Rosa Kristiansen; Niken Puruhita; Febe Christianto; Hertanto Wahyu Subagio; Enny Probosari
IJCNP : INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN Vol 6 No 1 (2023): IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN)
Publisher : Perhimpunan Dokter Gizi Klinik Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54773/ijcnp.v6i1.156

Abstract

Latar belakang : Phase angle (PhA) yang merupakan indikator integritas seluler mungkin berhubungan dengan tingkat keparahan IM yang tercermin dari penanda cedera miosit yaitu kadar troponin. Tujuan : Menganalisis hubungan PhA dengan tingkat keparahan IM. Metode : Penelitian observasional, melibatkan 40 subjek dengan IM yang memenuhi kriteria inklusi dan eksklusi. Tingkat keparahan IM diukur dari kadar troponin I, PhA didapatkan dari bioelectrical impedance analysis, dan data komorbid diambil dari rekam medis pasien. Uji hipotesis menggunakan analisis bivariat untuk melihat hubungan phase angle dan beberapa komorbid dengan tingkat keparahan IM. Hasil : Mayoritas subyek penelitian berjenis kelamin laki-laki (82,5%), rerata usia 56,1 tahun, dan rerata IMT 25,56 kg/m2. Dislipidemia merupakan jenis komorbid yang paling banyak diderita (92,5%) dan 62,5% subyek penelitian memiliki 2 atau lebih komorbid. Hasil analisis bivariat PhA, jenis komorbid, jumlah komorbid, usia, IMT, dan jenis kelamin terhadap kadar troponin I adalah tidak signifikan (p>0,05). Kesimpulan : PhA, diabetes, hipertensi, dislipidemia, jumlah komorbid, usia, IMT, dan jenis kelamin tidak berhubungan dengan tingkat keparahan IM. Kata kunci : BIA, komorbid kardiovaskular, phase angle, tingkat keparahan infark miokard
Difference Between BMI At Admission and Discharge and NIHSS at Admission and Discharge In Iscemic Stroke Patients at Dr.Kariadi Horpital Fauziah, Annisa; Subagio, Hertanto Wahyu; Nugrohowati, Annta Kern; SS, Darmono; Probosari, Enny
Medica Hospitalia : Journal of Clinical Medicine Vol. 10 No. 1 (2023): Med Hosp
Publisher : RSUP Dr. Kariadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36408/mhjcm.v10i1.777

Abstract

BACKGROUND : Hospitalized patients are at risk for malnutrition. Decreased BMI (Body Mass Index) in stroke patients is negatively correlated with patient outcomes. Studies on differences in BMI and NIHSS (National Institutes of Health Stroke Scale) at admission and discharge in stroke patients have not been conducted in Indonesia. OBJECTIVE: To describe the difference between BMI and NIHSS at admission and discharge in ischemic stroke patients at Dr. Kariadi hospital METHOD : An observational study on 49 hospitalized ischemic stroke patients at the Stroke Unit of dr. Kariadi hospital. Outcomes were measured using the National Institutes of Stroke Scale (NIHSS). Data was collected from the patient's medical record and analyzed using Paired Sample t Test. RESULT : There was no significant difference between BMI at admission and discharge (p = 0.161). There was a significant difference between the NIHSS at the time of admission and at the time of discharge (p= 0.014). CONCLUSION : There is no significant difference between BMI at admission and discharge. There is functional improvement in ischemic stroke patients during treatment
Effect of vitamin D3 supplementation on serum 25 (OH)D Levels, hand grip strength, blood sugar levels, and cognitive function in the elderly Probosari, Enny; Subagio, Hertanto Wahyu; Winarni, Tri Indah; Nugroho, Heri; Manikam, Nurul Ratna Mutu
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 13, No 1 (2024): December
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jgi.13.1.79-87

Abstract

ABSTRACTBackground: The aging process in the elderly can be caused by a decrease in vitamin D precursors and reduced Vitamin D levels due to impaired absorption of Vitamin D. Vitamin D plays a role in cognitive function, acts as an immunomodulator affecting blood glucose levels, promotes muscle atrophy, and affects the intranuclear VDR concentration and gene expression of VDR.Objectives: To determine the effect of vitamin D3 supplementation on Serum 25(OH)D levels, hand grip strength, blood sugar levels, and cognitive function in the elderly.Materials and Methods: This study used a quasi-experimental pre-posttest control group design with a total of 60 subjects included and divided into two groups. The treatment group received vitamin D3 at a dosage of 1000 IU/day for three months, while the control group was given a placebo. Blood serum levels were used to obtained serum 25(OH)D and blood sugar level. Hand grip strength values were measured by a hand grip dynamometer, and cognitive function was assessed using the Mini-Mental State Examination (MMSE) Questionnaire. The data was analyzed using the Wilcoxon test, and the bivariate analysis was performed using the Mann-Whitney test.Results: Most subjects were between 60 and 92 years old and had a vitamin D deficiency. Significant (P<0,05) differences were observed in serum 25(OH)D levels, blood sugar levels, and cognitive function following the intervention. The differences in serum 25(OH)D levels were 8,50±6,17, blood sugar levels were -21,68±25,88, and cognitive function was 2,23±3,05. Additionally, hand grip strength increased after the intervention (mean=0,42±4,66) but was not statistically significant (P=0,633).Conclusion: There is an improvement in cognitive function and a decrease in blood glucose levels, along with an increase in 25(OH)D levels after three months of vitamin D supplementation. However, hand grip strength did not significantly increase after supplementation.Keywords: Vitamin D3 Supplementation; serum 25(OH)D; hand grip strength; blood sugar level; cognitive function; elderly.
Co-Authors Adriyan Pramono Ag Soemantri Agustinus Soemantri Ali Manfaluthi Ahmad Amalia Sukmadianti Amalia Sukmadianti Amin Samiasih Annisa Fauziah, Annisa Annta Kern Annta Kern Nugrohowati Annta Kern Nugrohowati Apoina Kartini Apoina Kartini Aris Sudiyanto Aryu Candra Atmaja, Diana Bagoes Widjanarko Banundari Rachmawati Besari Adi Pramono Binar Panunggal Budi Santoso Camelia Bomaztika Sari Darmono SS Darmono SS Denny Apriyanto Dewi Masitha Dewi, Amalia Andansari Dewi, Clara Rashinta Dian Ratna Sawitri Dodik Tugasworo EDI DHARMANA Edi Dharmana Enny Probosari Enny Probosari Etisa Adi Murbawani Eunika Lusiana Febe Christianto Febe Christianto Febriana Rahmawati Hardhono Susanto Hardian Hardian Hardono Susanto, Hardono Hartanti Sandi Wijayanti Henna Rya Sunomo Heri Nugroho Jennifer Setiawan Joriandhita Ramadhan Lisyani Suromo Luciana Sutanto Lukman, Petrin Redayani M Herumuryawan M Mexitalia M Sakundarno Maharatih, Gusti Ayu MARTHA ARDIARIA Mexitalia Mexitalia Minidian Fasitasari Mohammad Zen Rahfiludin MR Arientasari Himawan MS Anam Muchlis Achsan Udji Muchlis Ahsan Udji Sofro Muhammad Heru Muryawan Muhammad Sulchan Muji Mulyati Nanan Sekarwana Natalia Dewi Wardani Nathalia Safitri Niken Puruhita Nugrahaningsih Nugrahaningsih Nurrohmiati, Siti Nurul Ratna Mutu Manikam Nuryanto Nuryanto Nyoman Suci Widyastiti Phitra Sekar Dianggra Pusaka, Semerdanta Retnaningsih - Rimahardika, Rosita Riwanto Rosa Kristiansen Roziana Roziana, Roziana RRJ. Sri Djokomoeljanto Santi Rahayu SARJADI SARJADI Septiawan, Debree Sofyan Harahap Sri Djokomoeljanto suhartono - Suhartono Suhartono Suhartono, Suhartono Suharyo Hadisaputro Suharyo Hadisaputro Suprapti, Rini Suratman Suratman Susilo, Kezia Natalia Daniast Taufik Hilmansyah Tri Indah Winarni Ulfa, Viny Rosaliana Wendiranti, Catra Ibriza Widiastuti, Maria Immaculata Widya Budiarni Wijayanto Wijayanto Wiwid Widiyatni Wiwid Widiyatni, Wiwid Yuliyani, Ni Nyoman Sri