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All Journal Statistika Jurnal Peluang Proceedings of Annual International Conference Syiah Kuala University - Social Sciences Chapter Jurnal Gaussian Jurnal Pengajaran MIPA Jurnal Statistika Universitas Muhammadiyah Semarang Jurnal Pengajaran Matematika dan Ilmu Pengetahuan Alam Jurnal Riset Pendidikan Matematika Jurnal Elemen Jurnal Informatika Upgris Jurnal Penelitian Pendidikan IPA (JPPIPA) Numeracy : Jurnal Ilmiah Pendidikan Matematika International Journal for Educational and Vocational Studies ESTIMASI: Journal of Statistics and Its Application Journal of Applied Data Sciences Narra J International Journal of Education and Digital Learning (IJEDL) Jurnal Natural Jurnal Pendidikan Sains Indonesia (Indonesian Journal of Science Education) Heca Journal of Applied Sciences Journal of Educational Management and Learning Infolitika Journal of Data Science PESARE: Science and Engineering Service Journal Jurnal Didaktik Matematika Eduma : Mathematics Education Learning and Teaching
Muhammad Subianto
Department Of Statistics, Faculty Of Mathematics And Natural Science, Universitas Syiah Kuala, Banda Aceh 23111, Indonesia
Agriculture, Biological Sciences & Forestry Astronomy Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Physics Public Health Social Sciences Other

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Identification and Analysis of Potential Breast Anticancer Agents in Pogostemon Cablin through Network Pharmacology Syarifah Fathimah Azzahra; Essy Harnelly; Muhammad Subianto; Wisnu Ananta Kusuma; Widya Sari
Jurnal Penelitian Pendidikan IPA Vol 10 No SpecialIssue (2024): Science Education, Ecotourism, Health Science
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10iSpecialIssue.7049

Abstract

Breast cancer is one of the highest known causes of death in Indonesia, especially for women. Pogostemon cablin Benth is one of the Aceh's endemic herbal plants that has been studied to have potential such as anti-inflammatory, antiproliferative, antioxidant, antimicrobial, and proapoptotic. Network pharmacology approach was conducted to explore and analyze the potential of P. cablin as an anti-breast cancer. P. cablin plant compounds were obtained from GCMS and breast cancer genes data were obtained from OMIM, GeneCard, and DisGeNet databases. Target proteins and pathways involved were identified using STRING-DB and Metascape. Network analysis was performed using Cytoscape. A total of 65 plant compounds with 554 target proteins and 1854 disease genes were obtained. Based on the results of combining protein targets using Venn diagrams, 138 overlapping proteins between drug compounds and breast cancer disease targets were identified. Based on KEGG and GO analysis, P. cablin is known to have potential in breast cancer treatment/therapeutic mechanisms. Based on the "compound-protein target-pathway" multi-target mechanism, pogostol; 1H-Cycloprop[e]azulen-7-ol, decahydro-1,1,7-trimethyl-4-methylene-, [1ar-(1aα,4aα,7β,7aβ,7bα)]-; 3-Hexen-1-ol, 2,5-dimethyl-, acetate, (Z)-, 5β,7βH,10α-Eudesm-11-en-1α-ol; Acetic acid, 3-hydroxy-6-isopropenyl-4,8a-dimethyl 1,2,3,5,6,7,8,8a-octahydronaphthalen-2-yl ester; and Humulenol-II interacts with proteins that play a significant role in breast cancer, which are MAPK1, EGFR, TNF, AKT1, and JAK2. Hence, it can be concluded that P. cablin has good potential to be a source of therapeutic treatment against breast cancer. However, it needs to be tested clinically to further determine the effects of this P. cablin compound.
Design and Development of Website and Android-Based Aceh Biodiversity Applications Muhammad Subianto; Essy Harnelly; Alim Misbullah; Razief Perucha Fauzie Afidh; Fikrul Akhyar; Muhammad Irfan; Wira Dharma; Nazaruddin; Zulfan
Jurnal Penelitian Pendidikan IPA Vol 11 No 4 (2025): April
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i4.10535

Abstract

Aceh is an exceptional region in Indonesia characterized by significant biodiversity and abundant natural wealth. Despite these numerous benefits, there is limited information regarding the potential of biodiversity in this region. Therefore, this research aimed to design and develop Website and Android-based applications to facilitate access to information regarding biodiversity in Aceh. In the development process, the Waterfall method was used, and the applications consisted of two main components, namely the back-end and the front-end. The users were divided into three categories, including contributors, verificators, and admins. After the development was complete, functionality testing was conducted using the black box method, and usability was examined using the Post-Study System Usability Questionnaire (PSSUQ). The results of functionality testing showed that both applications operate efficiently, thereby providing users with a satisfying experience when accessing information about Aceh biodiversity. The usability score was approximately 7 for Website-based and 6 for Android-based applications, showing a high level of usability.
Mathematical Connection Ability through the Application of the AIR (Auditory Intellectualy Repetition) Learning Model Assisted by Geogebra Software Ainal Mardhiah; M. Ikhsan; Muhammad Subianto
International Journal of Education and Digital Learning (IJEDL) Vol. 1 No. 4 (2023)
Publisher : Lafadz Jaya Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/ijedl.v1i4.21

Abstract

expected model scan fosters students' mathematical connection skills, namely through the application of the AIR (Auditory Intellectual Repetition) model assisted by geogebra software. The purpose of this study was to determine differences in students' mathematical connection abilities after obtaining learning by applying the AIR (Auditory Intellectual Repetition) model assisted by geogebra software. This study used a quantitative approach with a pre-test and post-test control group design. The population of this study was class IX students of SMPN 1 Peukan Pidie by taking samples of two classes consisting of an experimental class and a control class. The sample selection was done by random sampling. The instrument used is a mathematical connection ability test. The data analysis technique uses the ANOVA test. Based on the results of the study, it was found that there were differences in the mathematical connection abilities of students who were taught through the application of the AIR (Auditory Intellectual Repetition) model assisted by geogebra software with conventional learning. Furthermore, the results of this study also identified that there was no interaction between learning and student level on students' mathematical connection abilities.
DEVELOPMENT OF STRAIGHT LINE EQUATION MODULE BASED ON GUIDED INQUIRY LEARNING TO IMPROVE THE MATHEMATICAL CONNECTION ABILITY OF MIDDLE SCHOOL STUDENTS Almunir Sihotang; Muhammad Subianto; Zainal Abidin
EduMa: Mathematics education learning and teaching Vol. 8 No. 1 (2019)
Publisher : Jurusan Tadris Matematika UIN Siber Syekh Nurjati Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24235/eduma.v8i1.3800

Abstract

Seeing students' mathematical connection ability is low, indicating that students' ability to study mathematics is also low. The media that fits this condition is the learning module. The research problem formulation is whether the development of guided inquiry based straight line equation learning can improve the mathematical connection ability of class VIII students?. The purpose of this research is to know module learning development equation-based guided inquiry straight line can improve the ability of class VIII student of mathematical connections. This research is through the Research and Development (R and D) research process. The subject of this research is the State Middle School students 3 Unggul Ingin Jaya as many as 20 students. The analysis in this study uses a questionnaire for students, the feasibility of a learning module that is an assessment by an expert (validator) using a questionnaire validity of material experts, student learning outcomes, student responses to the learning module. The results of the validator's assessment state an average of 3.45 in the valid category, while the average value of 3,25 in the category is quite effective. The average N-gain value of the experimental class is 0,36 compared to the N-gain average of the control class 0.33. The conclusions in this study are the development of a module of straight line equations with an inquiry approach can improve the mathematical connection ability of class VIII students of Middle School. Keywords: Module development equation of a straight line, connection matematics, Inquiry
Co-Authors . Zulfan Ahmad, Noor Atinah Ainal Mardhiah Ainal Mardhiah Alfian Futuhul Hadi Alim Misbullah Almunir Sihotang Asep Rusyana Baehaqi Bagus Sartono Cut Morina Zubainur Cut Mulyawati Cut Rina Rossalina Dwi Fadhiliani Earlia, Nanda Essy Harnelly Essy Harnelly EVI RAMADHANI Farsiah, Laina Fikrul Akhyar Fitriana AR Furqany, Nuwairy El Ghazi Mauer Idroes Hijriyana P., Meildha Hizir Sofyan Husdayanti, Noviana Idroes, Ghalieb Mutig Idroes, Ghazi M. Idroes, Ghifari M. INA YATUL ULYA Indah Manfaati Nur Irnanda , Irnanda, Irnanda Irvanizam, Irvanizam Jamil, Muhammad Salsabila Kairupan, Tara S. Kurniadinur, Kurniadinur M. Ikhsan M. Ikhsan M. Ikhsan M. Ikhsan Maulana, Aga Miftahuddin Miftahuddin Miftahuddin Miftahuddin Miftahuddin Mikyal Bulqiah, Mikyal Misbullah, Alim Muhammad Al Agani Muhammad Iqbal Muhammad Irfan Mukhamad Najib Mursyida, Waliam Nazaruddin Nisya Fajri Nurbaiti Nurbaiti Nurdjannah J. Niode Nurjani Nurjani Nurjannah Nurjannah Nurleila, Nurleila Prakoeswa, Cita RS. Purnama Mulia Farib Rahmah Johar Razief Perucha Fauzie Afidh Razief Perucha Fauzie Afidh Reza Wafdan Rika Fitriani Rika Siviani Rinaldi Idroes Rizal Munadi RR. Ella Evrita Hestiandari S.Pd. M Kes I Ketut Sudiana . Salmawaty Salmawati Salmawaty Salmawaty Sasmita, Novi Reandy sufriani, sufriani Sugara, Dimas Rendy Suhendra, Rivansyah Suryadi Suryadi Syarifah Fathimah Azzahra Teuku Rizky Noviandy Tuti Asmiati Vivi Dina Melani Vivi Dina Melani Vivi Dina Melani Widya Sari Wira Dharma Wisnu Ananta Kusuma Yusrizal Yusrizal Zahriah, Zahriah Zainal Abidin Zainal Abidin Zainal Abidin Zhilalmuhana, Teuku Zulfan