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MALONDIALDEHIDE (MDA) URINE AS AN EARLY MARKER OF DEVELOPMENTAL DISORDERS OF CHILDREN LIVING AROUND GOLD MINES Ernawati; Adi Heru Sutomo; Indwiani Astuti; Enda Silvia Putri; Marniati; Itza Mulyani; Sufyan Anwar; Eva Flourentina Kusumawardani; Suci Eka Putri; Hasanuddin Husin
Multidiciplinary Output Research For Actual and International Issue (MORFAI) Vol. 4 No. 2 (2024): Multidiciplinary Output Research For Actual and International Issue
Publisher : RADJA PUBLIKA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54443/morfai.v4i2.1664

Abstract

Children born to mothers living around gold mines are at risk of mercury exposure (Hg) and can cause developmental disorders. These developmental disorders can be detected early through stress oxidation mechanisms based on Hg toxicity that directly harm brain cells. It can be detected early on from the level of DNA damage, which is malondialdehyde (MDA) in the urine. Examining children's MDA urine levels near gold mines is the aim of this study. The Observational Research Method performs measurement of MDA of baby urine with TBARS examination of 16 babies in the age range of 2-14 weeks babies who live around the gold mining village Kalirejo Prefecture Kokap district of Kulon Progo Yogyakarta. The result was a rate of 3.23 μmol/L of MDA in baby urine, which is above the normal level of 1.03 μMol/L. So it can be concluded that the high level of MDI in the baby's urine is an early indication of a child's developmental disorder living around the gold mining.
Descriptions of Child Developmental Disorders Living Around Gold Mining Ernawati, Ernawati; Sutomo, Adi Heru; Astuti, Indwiani; Putri, Enda Silvia; Putri, Suci Eka; Marniati, Marniati; Mulyani, Itza
Journal of Nutrition Science Vol 5, No 1 (2024): May, 2024
Publisher : Universitas Teuku Umar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35308/jns.v5i1.9945

Abstract

Living around the gold mining area, at risk of exposure to mercury (Hg). Pregnant women exposed to Hg alkyl can cause fetal brain damage so that the baby is born with d  efects. This is due to the target toxicity of Hg, especially the organic metal compounds are the nervous system. Based on a child development screening questionnaire, ±100 children were questioned about their development, motor development, language and social interaction. This research was to see a picture of the development of children living around the Gold Mining village of Kalirejo, Kokap district, Kulon Progo District, Yogyakarta.  The Longitudinal Observational Research Method with serial measurement measured the level of child development in five domains: cognitive, linguistic, motor, social, emotional and behavioral (adaptive behavior) with the Bayley Scale of Infant and Toddler Development Third Edition (BSID III) against 16 infants in the age range of 2-14 weeks (stage I) and 14-26 weeks. (tahap II). The baby's development observations resulted in an average composite development score of 85. Stage I obtained composite scores of cognitive domain; 102.81, language; 107.38, motor: 98.94, social emotional: 100,63 and behavioral: 90.00, while Stage II of each domain had the same scores as 105.94 : cognitive, 105.38: language, 104.81: motor, social-emotional: 98,69 and behavioural: 92.44. The conclusion that the composite child development score was in the average range of 90 - 109 for all domains, means that the child development composite score was still within the normal range (85-115), indicating that there is no developmental impediment. It is recommended to reduce Hg exposure, provide optimal nutrition to the baby and enhance developmental interventions with stimulation to stimulate auditorium, visual, tactile and kinesthetic, thereby improving the quantity and quality of brain cell synapses, to optimize brain function. 
Development of Pandemic Burnout Inventory for Health Personnel Phuspa, Sisca Mayang; Dharmastuti, Anjarie; Sutomo, Adi Heru; Alim, Syahirul
Kesmas Vol. 18, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The COVID-19 pandemic has increased the workload of health personnel in Indonesia, and the risk of burnout has thus doubled. Several instruments exist to assess burnout, but none have been specifically developed for health personnel during the COVID-19 pandemic. Therefore, to close this gap, developing a Pandemic Burnout Inventory for health personnel is important. This study used mixed methods with a sequential exploratory design at five COVID-19 referral hospitals. A total of 30 informants were employed in the qualitative phase, selected using an intensity sampling approach, and 731 respondents in the quantitative phase were obtained in field trials and online questionnaires. Finally, a Pandemic Burnout Inventory was formed with 14 items. The content validity, based on expert judgment, showed very good results. The assessment of item discrimination and construct validity showed good results. The concurrent validity and reliability of the instrument showed fairly good results. In general, the Pandemic Burnout Inventory meets the criteria for a good instrument according to psychometrics: it is objective, standard, valid, and practical. Health care institutions can use this instrument to evaluate and prevent the deterioration of the mental health condition of health personnel handling COVID-19 or similar health crises.
Co-Authors - Sudiyono - Sudiyono . Norlatifah Abu Tholib Aman Ade Indah Wahdini Agus Surono Agus Suwarni Angelina Candra Dewi Anggit Pratiwi Angki Irawan Anjarie Dharmastuti Anwar, Sufyan Apriyani Apriyani Arifin Arifin Ariyanto Nugroho Baiq Liana Widiyanti Carla R. Marchira Carla R. Marchira Cempaka Tursina Dina Merisa Damanik Dyah Suryani Enda Silvia Putri Endang Tri Wahyuni Ernawati Ernawati Eva Flourentina Kusumawardani Fitriana Fitriana Hariyono, Widodo Hariyono, Widodo hartono hartono Husin, Hasanuddin Ig. L. Setyawan Purnama Ika Ambar Trisnawati Ika Muthya Anggraini Ika Muthya Anggraini Indwiani Astuti Ishana Balaputra Iswanto Iswanto Iswanto Iswanto Itza Mulyani Joko Subandono Khayan Khayan Mahar Agusno Marniati Marniati Marniati, Marniati Mora Claramita Mulyani, Itza Nanda Kusumaningrum Nasution, Annio Indah Lestari Norlatifah, . Norlatifah, . Nur Alifa Istiani Phuspa, Sisca Mayang Purnama, Setyawan Purwanta Purwanta Putri, Enda Silvia Putri, Suci Eka Rahmat Hidayat Reni Wijayanti Sarto Setiadi Setiadi Setiadi, Setiadi Setiarni, Sri Marisya Setiarni, Sri Marisya Sitti Rahmah Umniyati Soeyoko Soeyoko Soeyoko Soeyoko Solikhah Solikhah Sri Marisya Setiarni Sri Mukti Suhardini, Sri Mukti Sri Puji Ganefati Su Ritohardoyo Suci Eka Putri Sudarmadji Sudarmadji SUDARMAJI SUDARMAJI Sukandarrumidi Sukandarrumidi Sukandarrumidi Sukandarrumidi Sumardiyono Sumardiyono Sumarni Sumarni Susi Iravati Susi Iravati Susi Iravati Suyitno Suyitno Syahirul Alim Tanto Kusworo Thaharuddin Thaharuddin, Thaharuddin Triatmi Dyah Wahyuning Wahyu Pamungkasih Widodo Hariyono Widodo Hariyono Widodo Hariyono Widya Asmara Windi Wulandari Yayi Suryo Prabandari Yulia Dewi Irawati Yulia Rina Wijaya Yulia Rina Wijaya Yuni Wijayanti Zuzun Nazila