Hermawan Udiyanto
Faculty Of Medicine, Universitas Sebelas Maret / Department Of Obstetrics And Gynecology, Dr. Moewardi Hospital, Ir. Sutami 36 A, Kentingan Surakarta 57126 Telp. (0271) 662622

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Insidensi Infeksi Bayi Baru Lahir Berdasarkan Lama Ketuban Pecah Dini di RSUD Dr. Moewardi Surakarta Ernawati, Rika; Udiyanto, Hermawan; Wicaksono, Bagus
Nexus Kedokteran Klinik Vol 3, No 3 (2014): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (14.046 KB)

Abstract

Background: The incidence of Premature Rupture of Membranes (PROM) approaches 10% of all delivered which one of the most pregnancy complications. During the latency period of PROM, the bacterias raise inflammation in the vagina, move up in the fetal membranes, umbilical cord, and placenta. Fetal infection caused by aspiration of infected amniotic fluid may lead neonatus stillbirth, preterm delivery, or neonatal sepsis. This study conducted to prove the differences of the incidence in neonatal infection based on the latent period of PROM at Dr. Moewardi Surakarta Hospital. Methods: An observational analytic study with cross sectional method conducted to mother criteria which were term gestation, aged around 20-35 years old, spontaneous vaginal delivery, give birth an infant with a birth weight ≥ 2500 grams. The independent variable was a latent period of PROM while the dependent variable was a neonatal infection. The subjects were divided into two groups: PROM < 24 hours and PROM ≥ 24 hours. Further, their neonatal were observed the results of blood culture, leukocyte, neutrophil, thrombocyte, and temperature through medical records. The variable was analyzed by Chi Square test. Results: The subjects were 64 samples in two groups, each consisted of 32 samples. The result of the test stated that the p -value was 0.040 (p < 0.05) with RR = 3.400, thus it could be conclude that there was a statistically significant difference in the incidence of neonatal infection based on the latent period of PROM, where the neonatal at PROM ≥ 24 hours had opportunity 3.4 times more than the risk of infection of the PROM  < 24 hours. Conclusion: There was a statistically significant difference in the incidence of neonatal infection based on the latent period of PROM at Dr. Moewardi Surakarta Hospital. Keywords: Premature Rupture of Membranes, Neonatal infection, Blood culture 
Ekspresi Heat Shock Protein 70 (HSP70) dan Caspase-3 sebagai Prediktor terhadap Operabilitas Kanker Serviks Stadium IIB setelah Mendapat Kemoterapi Neoajuvant Paclitaxel-Carboplatin Udiyanto, Hermawan; Askandar, Brahmana; Fauziah, Dyah
Indonesian Journal of Cancer Vol 7, No 3 (2013): Jul - Sep 2013
Publisher : "Dharmais" Cancer Center Hospital

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Abstract

Penelitian ini bertujuan untuk mengetahui peran ekspresi HSP70 dan Caspase-3 terhadap keberhasilan operabilitas kanker serviks stadium IIB setelah pemberian kemoterapi neoajuvant Paclitaxel-Carboplatin 3 seri. Metode: ekspresi HSP70 dan caspase-3 diperiksa dengan pengecatan imunohistokimia pada 40 potongan biopsi jaringan pasien kanker serviks IIB yang memenuhi kriteria inklusi, yang melakukan pengobatan di RSUD dr. Soetomo, Departemen Obstetri dan Ginekologi, Fakultas Kedokteran Universitas Airlangga, Surabaya, mulai Desember 2006 hingga Juli 2011. Kriteria inklusi meliputi penderita yang telah dilakukan evaluasi keberhasilan terapi (operabilitas) pasca-kemoterapi neoajuvant Paclitaxel-Carboplatin sebanyak 3 seri berturut-turut, dengan interval pemberian 3 minggu. Evaluasi keberhasilan terapi (operabilitas) tidak mengikuti kriteria respons terapi berdasarkan RECIST (Response Evaluation Criteria in Solid Tumours). Waktu pemeriksaan 3 – 4 minggu setelah pemberian kemoterapi yang terakhir. Operabilitas tumor, yaitu kondisi klinis kanker serviks di mana pada pemeriksaan dalam vagina (vaginal toucher/VT) dan pemeriksaan dalam rektum oleh tim ginekologi onkologi setelah penderita mendapatkan kemoterapi neoajuvant Paclitaxel-Carboplatin 3 seri dinyatakan bahwa pada parametrium secara klinis tidak didapatkan infiltrasi tumor. Jenis dan bentuk penelitian ini merupakan penelitian analitik observasional, studi case control pada penderita kanker serviks IIB yang mendapat kemoterapi neoajuvant Paclitaxel-Carboplatin sebanyak 3 kali dengan interval pemberian kemoterapi 3 minggu.Hubungan antara ekspresi HSP70 dan caspase-3 dengan operabilitas post-kemoterapi neoajuvant Paclitaxel-Carboplatin dianalisis dengan regresi logistik. Ekspresi HSP70 negatif dan HSP70 positif mempunyai jumlah total yang sama, yaitu 20 orang (50%), masing-masing 9 orang pada kelompok operabel dan 11 orang pada kelompok inoperabel. Tidak ada perbedaan yang bermakna hubungan antara HSP70 dengan operabilitas ( p = 1 ), dengan OR = 1,00 ( 95%CI : 0,28-3,47 ). Ekspresi caspase-3 positif sebanyak 24 orang (60,0%), masing-masing 13 orang pada kelompok operabel dan 11 orang pada kelompok inoperabel. Pada ekspresi Caspase-3 negatif, sebanyak 16 orang (40,0%), masing-masing 5 orang pada kelompok operabel dan 11 orang pada kelompok inoperabel. Tidak ada perbedaan yang bermakna hubungan antara ekspresi caspase-3 dengan operabilitas ( p = 0,154 ), dengan OR = 0,06 ( 95%CI : 0,69-9,81). Kombinasi antara ekspresi HSP70 (+) dan ekspresi caspase-3 (-), sebanyak 8 orang (20%), masing-masing 2 orang pada kelompok operabel dan 6 orang pada kelompok inoperabel. Sedangkan pada kelompok selain kombinasi antara ekspresi HSP70 (+) dan ekspresi caspase-3 (-) sebanyak 32 orang (80%), masing-masing 16 orang pada kelompok inoperabel dan 16 orang pada kelompok operabel. Tidak ada perbedaan yang bermakna hubungan antara kombinasi ekspresi HSP70 (+) dan ekspresi caspase-3 (-) dengan operabilitas ( p = 0,217 ), dengan OR = 3,0 ( 95 % CI : 0,525-17,159).Kesimpulan: ekspresi HSP70 dan caspase-3 tidak dapat dijadikan sebagai prediktor operabilitas pada kanker serviks stadium IIB yang mendapatkan neoajuvant kemoterapi Paclitaxel-Carboplatin.Kata kunci: Kanker serviks stadium IIB, kemoterapi neoajuvant Paclitaxel-Carboplatin, operabilitas pascakemoterapi neoajuvant.
Improved Understanding of IUD and Implant Family Planning Acceptors in Family Planning Services at Solo Peduli Clinic Budihastuti, Uki Retno; Laqif, Abdurahman; Melinawati, Eriana; Prakosa, Teguh; Udiyanto, Hermawan; Priyanto, Heru; Darto, Darto; Ratnasari, Affi Angelia; Anggraeni, Asih; Prisasanti, Dympna Prameilita
Journal of Maternal and Child Health Vol. 5 No. 4 (2020)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Abstract

Background: Family planning acceptor's understanding of intra uterine device (IUD) and implant contracep
Insidensi Infeksi Bayi Baru Lahir Berdasarkan Lama Ketuban Pecah Dini di RSUD Dr. Moewardi Surakarta Rika Ernawati; Hermawan Udiyanto; Bagus Wicaksono
Nexus Kedokteran Klinik Vol 3, No 3 (2014): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (14.046 KB)

Abstract

Background: The incidence of Premature Rupture of Membranes (PROM) approaches 10% of all delivered which one of the most pregnancy complications. During the latency period of PROM, the bacterias raise inflammation in the vagina, move up in the fetal membranes, umbilical cord, and placenta. Fetal infection caused by aspiration of infected amniotic fluid may lead neonatus stillbirth, preterm delivery, or neonatal sepsis. This study conducted to prove the differences of the incidence in neonatal infection based on the latent period of PROM at Dr. Moewardi Surakarta Hospital. Methods: An observational analytic study with cross sectional method conducted to mother criteria which were term gestation, aged around 20-35 years old, spontaneous vaginal delivery, give birth an infant with a birth weight ? 2500 grams. The independent variable was a latent period of PROM while the dependent variable was a neonatal infection. The subjects were divided into two groups: PROM < 24 hours and PROM ? 24 hours. Further, their neonatal were observed the results of blood culture, leukocyte, neutrophil, thrombocyte, and temperature through medical records. The variable was analyzed by Chi Square test. Results: The subjects were 64 samples in two groups, each consisted of 32 samples. The result of the test stated that the p -value was 0.040 (p < 0.05) with RR = 3.400, thus it could be conclude that there was a statistically significant difference in the incidence of neonatal infection based on the latent period of PROM, where the neonatal at PROM ? 24 hours had opportunity 3.4 times more than the risk of infection of the PROM < 24 hours. Conclusion: There was a statistically significant difference in the incidence of neonatal infection based on the latent period of PROM at Dr. Moewardi Surakarta Hospital. Keywords: Premature Rupture of Membranes, Neonatal infection, Blood culture
Peningkatan Pemahaman Akseptor KB terhadap Efek Samping IUD dan Implan dalam Pelayanan KB di Klinik Solo Peduli Uki Retno Budihastuti; Abdurahman Laqif; Eriana Melinawati; Teguh Prakosa; Hermawan Udiyanto; Heru Priyanto; Darto -; Affi Angelia Ratnasari; Asih Anggraeni
PLACENTUM: Jurnal Ilmiah Kesehatan dan Aplikasinya Vol 9, No 1 (2021): February
Publisher : Program Studi Kebidanan Fakultas Kedokteran Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/placentum.v9i1.44306

Abstract

ABSTRAKLatar Belakang: Pemahaman akseptor KB (Keluarga Berencana) tentang KB IUD dan implan masih rendah, hal ini dikarenakan minimnya pengetahuan dan adanya persepsi negatif mengenai kontrasepsi IUD dan implan di masyarakat. Perlu adanya upaya peningkatan pemahaman akseptor KB untuk meningkatkan kualitas dalam pelayanan KB untuk mencapai kesehatan individu yang optimal dan menurunkan angka fertilitas melalui peningkatan pemakaian alat kontrasepsi.Tujuan: Mengetahui pengaruh perlakuan penyuluhan terhadap peningkatan pemahaman dan kesiapan akseptor KB terhadap efek samping alat kontrasepsi di Klinik Solo Peduli.Metode: Pengabdi memberikan penyuluhan kepada akseptor KB mengenai KB IUD dan implan. Kemudian, Akseptor KB dibagikan kuesioner meliputi pertanyaan tentang efek samping yang dirasakan, serta langkah yang dapat dilakukan ketika efek samping timbul.Hasil: Dari 60 responden, didapatkan mayoritas tingkat pengetahuan efek samping alat kontrasepsi akseptor KB sebanyak 65% adalah “baik”, 35% adalah “kurang”, dan terdapat 18 (30%) orang yang mengalami efek samping minimal, diantaranya: nyeri, ketidaknyamanan hubungan seksual, kenaikan berat badan, jerawat, siklus mentruasi berubah setelah pemasangan alat kontrasepsi.Kesimpulan: Terdapat peningkatan pengetahuan efek samping alat kontrasepsi setelah dilakukan penyuluhan dan efek samping yang relatif minimal.Kata Kunci: Akseptor KB, IUD, Implan, Pelayanan KB. ABSTRACTBackground: The understanding of family planning acceptors about IUD and implant contraception is still low, this is due to the lack of knowledge and negative perceptions about IUD contraception and implants in the community. There needs to be an effort to increase understanding of family planning acceptors to improve the quality of family planning services to achieve optimal individual health and to reduce fertility rates through increased use of contraceptives.Objective: To determine the effect of counseling treatment on increasing understanding and readiness of family planning acceptors on the side effects of contraceptives at the Solo Peduli Clinic.Methods: The service provider provides counseling to family planning acceptors about IUD and implant family planning. Then, family planning acceptors were distributed questionnaires covering questions about side effects that were felt, as well as steps that could be taken when side effects arose.Results: Of the 60 respondents, it was found that the majority of the level of knowledge about the side effects of contraceptives acceptors of family planning as much as 65% were "good", 35% were "less", and there were 18 (30%) people who experienced minimal side effects, including: pain, discomfort of sexual intercourse, weight gain, acne, menstrual cycles changed after the insertion of contraceptives.Conclusion: There is an increase in knowledge of the side effects of contraceptives after counseling and the relatively minimal side effects.Keywords: family planning acceptors, IUD, implants, family planning services.
Ekspresi Heat Shock Protein 70 (HSP70) dan Caspase-3 sebagai Prediktor terhadap Operabilitas Kanker Serviks Stadium IIB setelah Mendapat Kemoterapi Neoajuvant Paclitaxel-Carboplatin Hermawan Udiyanto; Brahmana Askandar; Dyah Fauziah
Indonesian Journal of Cancer Vol 7, No 3 (2013): Jul - Sep 2013
Publisher : National Cancer Center - Dharmais Cancer Hospital

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1074.677 KB) | DOI: 10.33371/ijoc.v7i3.287

Abstract

Penelitian ini bertujuan untuk mengetahui peran ekspresi HSP70 dan Caspase-3 terhadap keberhasilan operabilitas kanker serviks stadium IIB setelah pemberian kemoterapi neoajuvant Paclitaxel-Carboplatin 3 seri. Metode: ekspresi HSP70 dan caspase-3 diperiksa dengan pengecatan imunohistokimia pada 40 potongan biopsi jaringan pasien kanker serviks IIB yang memenuhi kriteria inklusi, yang melakukan pengobatan di RSUD dr. Soetomo, Departemen Obstetri dan Ginekologi, Fakultas Kedokteran Universitas Airlangga, Surabaya, mulai Desember 2006 hingga Juli 2011. Kriteria inklusi meliputi penderita yang telah dilakukan evaluasi keberhasilan terapi (operabilitas) pasca-kemoterapi neoajuvant Paclitaxel-Carboplatin sebanyak 3 seri berturut-turut, dengan interval pemberian 3 minggu. Evaluasi keberhasilan terapi (operabilitas) tidak mengikuti kriteria respons terapi berdasarkan RECIST (Response Evaluation Criteria in Solid Tumours). Waktu pemeriksaan 3 4 minggu setelah pemberian kemoterapi yang terakhir. Operabilitas tumor, yaitu kondisi klinis kanker serviks di mana pada pemeriksaan dalam vagina (vaginal toucher/VT) dan pemeriksaan dalam rektum oleh tim ginekologi onkologi setelah penderita mendapatkan kemoterapi neoajuvant Paclitaxel-Carboplatin 3 seri dinyatakan bahwa pada parametrium secara klinis tidak didapatkan infiltrasi tumor. Jenis dan bentuk penelitian ini merupakan penelitian analitik observasional, studi case control pada penderita kanker serviks IIB yang mendapat kemoterapi neoajuvant Paclitaxel-Carboplatin sebanyak 3 kali dengan interval pemberian kemoterapi 3 minggu.Hubungan antara ekspresi HSP70 dan caspase-3 dengan operabilitas post-kemoterapi neoajuvant Paclitaxel-Carboplatin dianalisis dengan regresi logistik. Ekspresi HSP70 negatif dan HSP70 positif mempunyai jumlah total yang sama, yaitu 20 orang (50%), masing-masing 9 orang pada kelompok operabel dan 11 orang pada kelompok inoperabel. Tidak ada perbedaan yang bermakna hubungan antara HSP70 dengan operabilitas ( p = 1 ), dengan OR = 1,00 ( 95%CI : 0,28-3,47 ). Ekspresi caspase-3 positif sebanyak 24 orang (60,0%), masing-masing 13 orang pada kelompok operabel dan 11 orang pada kelompok inoperabel. Pada ekspresi Caspase-3 negatif, sebanyak 16 orang (40,0%), masing-masing 5 orang pada kelompok operabel dan 11 orang pada kelompok inoperabel. Tidak ada perbedaan yang bermakna hubungan antara ekspresi caspase-3 dengan operabilitas ( p = 0,154 ), dengan OR = 0,06 ( 95%CI : 0,69-9,81). Kombinasi antara ekspresi HSP70 (+) dan ekspresi caspase-3 (-), sebanyak 8 orang (20%), masing-masing 2 orang pada kelompok operabel dan 6 orang pada kelompok inoperabel. Sedangkan pada kelompok selain kombinasi antara ekspresi HSP70 (+) dan ekspresi caspase-3 (-) sebanyak 32 orang (80%), masing-masing 16 orang pada kelompok inoperabel dan 16 orang pada kelompok operabel. Tidak ada perbedaan yang bermakna hubungan antara kombinasi ekspresi HSP70 (+) dan ekspresi caspase-3 (-) dengan operabilitas ( p = 0,217 ), dengan OR = 3,0 ( 95 % CI : 0,525-17,159).Kesimpulan: ekspresi HSP70 dan caspase-3 tidak dapat dijadikan sebagai prediktor operabilitas pada kanker serviks stadium IIB yang mendapatkan neoajuvant kemoterapi Paclitaxel-Carboplatin.Kata kunci: Kanker serviks stadium IIB, kemoterapi neoajuvant Paclitaxel-Carboplatin, operabilitas pascakemoterapi neoajuvant.
Education on Assisted Reproductive Technology Program with Low Cost Uki Retno Budihastuti; Abdurahman Laqif; Eriana Melinawati; Teguh Prakosa; Hermawan Udiyanto; Heru Priyanto; Darto .; Affi Angelia Ratnasari; Asih Anggraeni; Agung Sari Wijayanti
Placentum: Jurnal Ilmiah Kesehatan dan Aplikasinya Vol 11, No 1 (2023): February
Publisher : Program Studi Kebidanan Fakultas Kedokteran Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/placentum.v11i1.64796

Abstract

Background: Assisted reproductive technology (ART) programs have proven to be a solution to help infertility couples to conceive. However, most couples face a financial crisis related to the relatively expensive cost of ART treatment. This service aims to educate about ART's meaning, direction, and procedures. Thus, couples want children to be able to understand the ART program at an affordable cost (low-cost) and undergo the ART program without any concerns about costs.Method: Seminar participants be given socialization in person and online through zoom software by the service provider. It is in two stages, in-person and online, so participants who cannot attend in person can follow this service program. In addition, participants are given a pre-test and post-test questions to assess their understanding of the ART program at an affordable cost.Result: The pre-test and post-test results were analyzed using Wilcoxon, which showed that after providing education about the ART program, the post-test results were significantly better than the pre-test results. Down value: 5.5%, fixed value: 15.2%, value rise: 79.3% with significance p<0.001.Conclusion: There are significant differences in the pre-test and post-test scores, which means that the participants understood the explanation the servicer gave.
Biopsychosocial Analysis of Factors on COVID-19 Screening Awareness of Infertile Couples in Assisted Reproductive Technology Budihastuti, Uki Retno; Laqif, Abdurahman; Melinawati, Eriana; Prakosa, Teguh; Udiyanto, Hermawan; Priyanto, Heru Priyanto; Darto, Darto; Rantasari, Affi Angelia; Wasyanto, Trisulo; Anggraeni, Asih; Wijayanti, Agung Sari
Journal of Maternal and Child Health Vol. 6 No. 5 (2021)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (36.67 KB) | DOI: 10.26911/thejmch.2021.06.05.04

Abstract

Background: The development of screening methods for infertility patients during the Coronavirus-2019 (COVID-19) pandemic provides new challenges in the adaptation of children's want programs in the era of the COVID-19pandemic. Several screening methods have been developed but various factors affect the awareness of couples to want to do COVID-19 screening. This study aimed to analyze biopsychosocial factors associated with awareness of COVID-19 screening in infertile couples. Subjects and Method: A cross-sectional study conducted at The Sekar Polyclinic of Dr. Moewardi Regional General Hospital during the COVID-19 pandemic. A number of 60 infertile couple of reproductive age who underwent the ART program was selected by random sampling. The dependent variable was awareness for COVID-19 screening. The independent variables were anxiety, knowledge, age, and length of infertility. The data were obtained from medical record and questionnaire and analyzed by a multiple logistic regression. Results: Anxiety (OR= 26; 95% CI; p<0.001) and above-average knowledge levels (OR=16; 95% CI; p<0.001) affected awareness for COVID-19 screening. While the age and length of infertility do not affect awareness for COVID-19 screening (p >0.05). Conclusion: Anxiety and above-average knowledge levels affect awareness for COVID-19 screening.
Expression of Bax Protein as A Prognosis Factor of Radiotherapy Response to Decreased Tumor Size in Stage IIB-IIIB Cervical Cancer Fitriawan, Ahmad; Udiyanto, Hermawan; Respati, Supriyadi Hari; Ratnasari, Affi Angelia; Prabowo, Wisnu
Journal of Maternal and Child Health Vol. 7 No. 3 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (35.074 KB) | DOI: 10.26911/thejmch.2022.07.03.07

Abstract

Background: Cervical cancer plays a role as the leading cause of cancer death for women in developing countries. Radiation therapy kills cancer cells through double strand breaks and the apoptotic process. Bax protein is one of the regulators of apoptosis. This study analyzed the role of Bax expression as a prognostic factor in radiation therapy response in reducing tumor size in patients with advanced cervical cancer (IIB-IIIB). Subjects and Method: This research is a retrospective cohort observational analytic study from January 2021 to April 2021 in the Department of Obstetrics and Gynecology in collaboration with the Department of Anatomical Pathology, Dr. Moewardi Hospital, Surakarta, Indonesia. This study involved 30 cervical cancer stage IIB-IIIB patients. The level of Bax expression was determined by immunohistochemical examination. ROC curve analysis was used to find cut-off points and evaluate the sensitivity and specificity of Bax in the prognosis of radiotherapy in patients with advanced cervical cancer (IIB-IIIB). Chi square test was used to determine the relationship between Bax expression and changes in tumor size in cervical cancer patients. Results: The ROC curve analysis showed that the AUC Bax score in prognosis of radiation therapy was 0.575 (CI 95%= 0.32 to 0.83) and the cutoff point was 62.5%. Based on the analysis of the ROC curve, the Bax expression of 62.5% shows a sensitivity of 56.5% and a specificity of 71.4%. Analysis of the relationship between Bax protein expression on changes in tumor size using the Chi Square test showed a P value of 0.390 (p> 0.05). Conclusion: The expression of Bax protein cannot play a role as a prognostic factor in the response of radiation therapy to the reduction in tumor size in stage IIB-IIIB uterine cervical cancer.
Efforts to Increase Understanding of COVID-19 Screening in Assisted Reproductive Technology Services Uki Retno Budihastuti; Abdurahman Laqif; Eriana Melinawati; Teguh Prakosa; Hermawan Udiyanto; Heru Priyanto; Darto .; Affi Angelia Ratnasari; Asih Anggraeni
Placentum: Jurnal Ilmiah Kesehatan dan Aplikasinya Vol 11, No 2 (2023): August
Publisher : Program Studi Kebidanan Fakultas Kedokteran Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/placentum.v11i2.74618

Abstract

Background: The assisted reproductive technology (ART) program for examining infertile couples requires face-to-face with a doctor. This face-to-face examination for the ART program has a risk for the transmission of COVID-19 to all medical personnel and infertile couples who want to undergo the ART program. This study aims to understand pre- and post-test education about COVID-19 screening on ART services.Methods: A total of 50 infertile couples in the ART program are given education online. The use of online methods using the Zoom application due to the COVID-19 pandemic. Evaluation of the level of understanding using pre and post-test providing education. Data analysis was carried out using the SPSS 23 application.Results: Analysis of the level of understanding of pre-test and post-test education using the Wilcoxon test. Pre-test results were 69.90±12.05, post-test 73.00±10.83 with significance values p<0.001. Chi-Square test analysis results obtained p<0.001 and OR = 15.68.Conclusion: There was a significant increase in understanding of COVID-19 screening in the post-test education ART service via the Zoom application compared to pre-test education.