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All Journal Jurnal Entropi Sainstek Jurnal Tadris Kimiya Lantanida Journal JSFK (Jurnal Sains Farmasi & Klinis) Jambura Journal of Educational Chemistry Jurnal Riset Rumpun Matematika dan Ilmu Pengetahuan Alam (JURRIMIPA) Jurnal Pendidikan Sains Indonesia (Indonesian Journal of Science Education) Nian Tana Sikka: Jurnal Ilmiah Mahasiswa Pentagon: Jurnal Matematika dan Ilmu Pengetahuan Alam Algoritma: Jurnal Matematika, Ilmu Pengetahuan Alam, Kebumian dan Angkasa Damhil: Jurnal Pengabdian kepada Masyarakat Jurnal Pendidikan Kimia, Fisika dan Biologi
Mangara Sihaloho
Universitas Negeri Gorontalo
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Earth & Planetary Sciences Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Mathematics Medicine & Pharmacology Public Health Social Sciences Other

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Pelatihan Pembuatan Pestisida Nabati Sebagai Alternatif Pengendalian Serangga Hama Tanaman Pada Petani Sayur di Desa Bulotalangi Timur Nurhayati Bialangi; Erni Mohamad; Mangara Sihaloho; Ahmad Kadir Kilo; Julhim S Tangio
Damhil: Jurnal Pengabdian kepada Masyarakat Vol 2, No 1: June 2023
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34312/damhil.v2i1.20825

Abstract

This service activity aims to provide training on making vegetable pesticides to farmers and housewives. As an alternative to controlling plant insect pests, the use of vegetable pesticides is considered safe to use. Botanical Pesticides are pesticides whose active ingredients come from plants or herbs and other organic materials which are efficacious in controlling pest attacks on plants. This pesticide does not leave harmful residues on plants or the environment and can be made easily using inexpensive materials and simple equipment. Vegetable pesticides are relatively easy to make with natural or vegetable ingredients which make these pesticides easy to decompose in nature so they don't pollute the environment. This organic pesticide is able to overcome and repel pests that destroy agricultural and plantation crops in general, such as fleas, caterpillars, grasshoppers and so on. The method used is direct training to groups of housewives and vegetable farmers using innovative technology. From the results of the implementation of these activities, the community was very enthusiastic about participating in these activities and was interested in making/producing their own pesticides from materials that are easy to obtain from the surrounding environment
Pencarian Inhibitor DYRK2 dari Database Bahan Alam Zinc15: Analisis Farmakofor, Simulasi Docking dan Dinamika Molekuler Aman, La Ode; Sihaloho, Mangara; Arfan, Arfan
JSFK (Jurnal Sains Farmasi & Klinis) Vol 10 No 1 (2023): J Sains Farm Klin 10(1), April 2023
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.10.1.100-113.2023

Abstract

DYRK2 (Dual-specificity tyrosine phosphorylation-regulated kinase 2) merupakan protein kinase yang memiliki banyak peranan dalam berbagai proses biologis, termasuk pembelahan sel, proliferasi sel, diferensiasi sel, dan apoptosis. DYRK2 diantaranya terlibat dalam regulasi siklus sel dengan cara mengatur aktivitas proteasom 26S sehingga inhibisi aktivitas DYRK2 dapat menghambat fungsi proteasom 26S dan mengurangi proliferasi sel kanker. Secara in vitro, kurkumin menunjukan kemampuan mengurangi proliferasi sel kanker melalui penghambatan enzim DYRK2. Pada penelitian ini, analog kurkumin telah diskrining dari database bahan alam Zinc15 dengan menggunakan model farmakofor yang diperoleg dengan pendekatan berbasis ligan. Hasil skrining kemudian dievaluasi dengan menerapkan teknik docking molekuler dan dinamika molekuler berdasarkan energi interaksi, rata-rata energi pengikatan bebas dan stabilitas interaksi antara ligan dan situs aktif DYRK2. Skrining terhadap 270.547 molekul dari database bahan alam Zinc15 menghasilkan 110 senyawa hit terpilih. Dengan mempertimbangkan hasil simulasi docking dan dinamika molekuler, tiga analog kurkumin prospektif telah dipilih yaitu ZINC000085597244, ZINC000217945958, dan ZINC000217643970. Molekul-molekul ini memiliki kriteria yang lebih baik dibandingkan kurkumin pada beberapa kriteria, seperti energi interaksi, energi pengikatan bebas, dan stabilitas interaksi dengan target. Disimpulkan, senyawa-senyawa ZINC000085597244, ZINC000217945958, dan ZINC000217643970 diprediksi sebagai kandidat potensial untuk obat anti-kanker dengan mekanisme aksi spesifik terhadap DYRK2.
The Effect of Ethnoscience Approach Through Problem Based Learning Model on Chemical Literacy Ability of Class XI Students on Reaction Rate Material at SMA Negeri 7 Gorontalo Riryn Tahir; Hendri Iyabu; Julhim S. Tangio; Mangara Sihaloho; Wiwin Rewini Kunusa; Thayban Thayban
Pentagon : Jurnal Matematika dan Ilmu Pengetahuan Alam Vol. 3 No. 1 (2025): Maret : Pentagon : Jurnal Matematika dan Ilmu Pengetahuan Alam
Publisher : Asosiasi Riset Ilmu Matematika dan Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/pentagon.v3i1.388

Abstract

The research aims to determine the effect of the ethnoscience approach through the problem-based learning model on the chemical literacy skills of Grade XI students in the reaction rate material at SMA Negeri 7 Gorontalo. The research employs a quasi experimental method with a nonequivalent control group design. The sample consisted of Grade XI IPA ( Natural Science) students from SMA Negeri 7 Gorontalo. The instrument used in this research was an essay test. Data processing and analysis were conducted using Microsoft Office Excel and SPSS version 16. The hypothesis test results on students’ post-test data using the Mann-Whitney test at a significance level of α = 0.05 showed that the Asymp. Sig. (2-tailed) value was less than 0.05 (0,002 < 0,05). Therefore, H1 was confirmed, and H0 was rejected. The N- Gain test results also indicated that the ethnoscience approach through the problem-based learning model was moderately effective in improving students’ chemical literacy skills in reaction rate material, with the experimental class achieving an N-Gain score percentage of 57.13% (moderately effective category), while the control class achieved a percentage of 31.42% (ineffective category). In conclusion, the ethnoscience approach through the problem-based learning model significantly affects students’ chemical literacy skills in reaction rate material.
Analisis Penguasaan Konsep Materi Senyawa Hidrokarbon Siswa Kelas XI SMA Moh Musli Malajai; Masrid Pikoli; Mangara Sihaloho; Julhim S. Tangio; Ahmad Kadir Kilo; Haris Munandar
Algoritma : Jurnal Matematika, Ilmu pengetahuan Alam, Kebumian dan Angkasa Vol. 3 No. 1 (2025): Algoritma : Jurnal Matematika, Ilmu pengetahuan Alam, Kebumian dan Angkasa
Publisher : Asosiasi Riset Ilmu Matematika dan Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/algoritma.v3i1.370

Abstract

This study aims to analyze students' conceptual mastery of hydrocarbon compounds. The method used in the study is descriptive qualitative. The study was conducted in the even semester of the 2023/2024 academic year. The subjects of this study were 59 students of class XI MIPA SMA Negeri 1 Limboto. The data collection technique used a concept mastery test instrument in the form of multiple choices that had been tested for validity and reliability. The results showed that conceptual understanding. The percentage of students in Determining the molecular formula and structure of hydrocarbon compounds obtained a percentage of 78.53% with a good category, on the indicator Distinguishing types of reactions and physical regularity of 67.80% with a sufficient category, on the indicator determining the isomers of hydrocarbon compounds of 40.68% with a less category, on the indicator analyzing the type of C atom based on the number of C atoms bound to the carbon atom chain of 27.12% with a less category, on the indicator predicting the type of isomers of hydrocarbon compounds, namely 38.42% with a less category and on the indicator correcting the structural formula of hydrocarbon compounds, namely 63.84% with a sufficient category. Then the total average percentage value is 52.73% with the Less category.
Pengaruh Model Pembelajaran CERDAS terhadap Hasil Belajar Siswa pada Materi Nanoteknologi di Kelas X SMA Negeri 7 Prasetya Gorontalo Zulfa K Muslimin; Mangara Sihaloho; Mardjan Paputungan; Julhim S. Tangio; Erni Mohamad; Thayban Thayban
Algoritma : Jurnal Matematika, Ilmu pengetahuan Alam, Kebumian dan Angkasa Vol. 3 No. 1 (2025): Algoritma : Jurnal Matematika, Ilmu pengetahuan Alam, Kebumian dan Angkasa
Publisher : Asosiasi Riset Ilmu Matematika dan Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/algoritma.v3i1.380

Abstract

This research aimed to examine the effect of the CERDAS learning model on student learning outcomes. The research employed a quasi-experimental method with a non-equivalent prest-posttest control group design. The sample consisted of students from class X Merdeka 3, serving as the experimental group, and class X Merdeka 1 as the control group. Both from SMA Negeri 7 Prasetya Gorontalo. These classes were selected using purposive sampling. The research instrument was an objective test. The results revealed a significant difference in the average scores between the experimental and control classes. Specifically, the average student learning outcome in the experimental group was 79,77, while in the control group, it was 67,27. Hypothesis testing using the t-tes yielded tcount value > ttable, indicated the tcount (2,99) was greater than the ttable value (2,01), which led to the rejection of H0 and confirmation of H1, Confirming that the CERDAS learning model had a significant effect on student learning outcomes. Additionally, the N-Gain test showed a moderate effect (0,68), indicating that the CERDAS learning model is fairly effective in improving student learning outcomes.
Pelatihan Pembuatan pupuk Organik dari Limbah Cucian Beras (L-AIBER) dan Limbah Kulit Nenas pada masyarakat Desa Bulotalangi Timur Mohamad, Erni; Bialangi, Nurhayati; Sihaloho, Mangara; Tangio, Julhim S; Zakaria, Perry
Damhil: Jurnal Pengabdian kepada Masyarakat Vol 3, No 2: December 2024
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/damhil.v3i2.29552

Abstract

Pengabdian kepada masyarakat ini bertujuan untuk memberikan pelatihan tentang pembuatan pupuk organik cair dari limbah cucian beras (L-AIBER) dan limbah kulit nanas kepada masyarakat Desa Bulotalangi Timur. Pelatihan ini diadakan sebagai upaya untuk meningkatkan kesadaran dan keterampilan masyarakat dalam memanfaatkan limbah rumah tangga menjadi produk yang bernilai guna tinggi serta ramah lingkungan.Metode yang digunakan dalam pelatihan ini meliputi penyampaian materi secara teoritis mengenai manfaat dan teknik pembuatan pupuk organik cair, diikuti dengan praktek langsung pembuatan pupuk oleh peserta. Hasil dari pelatihan menunjukkan bahwa peserta mampu memahami dan mempraktekkan teknik pembuatan pupuk organik cair dengan baik. Selain itu, pelatihan ini juga berhasil meningkatkan pengetahuan peserta mengenai pentingnya pengelolaan limbah rumah tangga dan manfaat pupuk organik bagi pertanian.Melalui program ini, diharapkan masyarakat Desa Bulotalangi Timur dapat secara mandiri memproduksi pupuk organik cair, mengurangi ketergantungan pada pupuk kimia, dan meningkatkan kualitas hasil pertanian. Program ini juga diharapkan dapat menjadi contoh bagi desa-desa lain dalam mengelola limbah rumah tangga secara produktif dan berkelanjutan.Kata Kunci: pelatihan, POC,  cucian beras,  kulit nanas
The Effect of STEM (Science, Technology, Engineering, and Mathematics) Learning Model on Critical Thinking Ability of Students on Colloid Material Lasim, Windi Sulistiyani; Musa, Weny J.A; Mohamad, Erni; Laliyo, Lukman Abdul Rauf; Iyabu, Hendri; Sihaloho, Mangara
Jambura Journal of Educational Chemistry Vol 7, No 1 (2025): February
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/jjec.v7i1.28516

Abstract

This research focuses on Natural Science learning, especially colloid material, where teaching is still dominated by the lecture method. Learning models that encourage students to make direct observations through experiments are rarely applied. This causes students to be less trained in solving problems, so their critical thinking skills are not optimally developed. This study aims to determine the effect of STEM (Science, Technology, Engineering, and Mathematics) learning model on students' critical thinking skills on colloid material at SMA Negeri 1 Telaga. The research design used was pre-experiment with one group pre-test post-test design. The research sample consisted of 29 students selected by census/total sampling. Data collection was done through critical thinking skills test. The results showed that the average percentage of students' critical thinking skills in the pre-test was 46.11%, which was in the medium category, and in the post-test it increased to 83%, which was in the very high category. This shows that the STEM learning model can improve students' understanding and critical thinking skills. The statistical test shows a significance value of 0.000 < 0.05, which means H1 is accepted and H0 is rejected. Thus, it can be concluded that the STEM learning model has a positive influence on students' critical thinking skills.
Analysis of Students' Metacognition Skills in Problem Solving on Thermochemical Materials Manaa, Ramayanti N; Lukum, Astin; Tangio, Julhim S; Pikoli, Masrid; Alio, La; Sihaloho, Mangara; Sangkota, Vivi Dia Afrianti
Jambura Journal of Educational Chemistry Vol 7, No 1 (2025): February
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/jjec.v7i1.26381

Abstract

This research is a descriptive qualitative research that aims to determine students' metacognition skills in problem solving on thermochemical material. The instrument used in this research is a 5-number description test in problem solving questions to measure students' metacognition skills. The subjects in this study were 34 students of class XI SMA Negeri 1 Tapa. The data analysis technique in this research is descriptive qualitative analysis which includes the stages of data reduction, data presentation, data analysis and conclusion drawing. The results showed that from the indicators of the questions given, students get an average value of the ability of metacognition skills for each indicator, namely: planning indicators by 67.8%, monitoring indicators by 48.2%, and evaluation indicators by 21.2%. The average results obtained on all indicators can be concluded that the ability of students' metacognitive skills on planning indicators is quite high, monitoring indicators are moderate, and evaluation indicators are low.
The Effect of Contextual Teaching and Learning (CTL) Model on Reaction Rate Material on Critical Thinking Ability and Character of Student Arwin, Muh.; Pikoli, Masrid; Sihaloho, Mangara; Kunusa, Wiwin Rewini; Tangio, Julhim S.; Munandar, Haris
Jambura Journal of Educational Chemistry Vol 7, No 1 (2025): February
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/jjec.v7i1.28723

Abstract

This research investigates the impact of the Contextual Teaching and Learning (CTL) model on critical thinking abilities and student character in the reaction rate topic at SMA Negeri 3 Gorontalo Utara. This research employs a quantitative methodology with a near-experimental design, specifically employing a one-group pre-test and post-test design. Data were gathered through questionnaires and tests. The study's population consisted of grade XI students at SMA Negeri 3 Gorontalo Utara throughout the opening term of the academic cycle for 2024-2025. A total sampling method was used, selecting 50 students from two classes who enrolled in chemistry specialization. The findings indicate that the application of the CTL model led to an improvement in critical thinking skills, with the experimental class showing a mean pre-test result of 37.56% and a post-test result of 84.22%, whereas the replication group recorded pre-test and post-test averages of 37.33% and 83.89%, respectively. As for character growth, the experimental group displayed an average score of 80.13%, while the replication group showed 79.90%. Both classes demonstrated significant progress, as shown by the consistency of the results in both groups. The outcomes of the paired sample t-test reveal a noteworthy value of 0.000 < 0.05, prompting the dismissal of H0 and the endorsement of Ha, confirming that the CTL model positively affects critical thinking skills and student character in reaction rate material.
Analisis Kemampuan Pemahaman Konsep Siswa pada Materi Hidrokarbon Menggunakan Three-Tier Multiple Choice Diagnostic Instrument : Literature Review Marsya Divya Olii; Nurhayati Bialangi; Julhim S. Tangio; Mangara Sihaloho; Erga Kurniawati
Jurnal Pendidikan Kimia, Fisika dan Biologi Vol. 1 No. 3 (2025): Mei : Jurnal Pendidikan Kimia, Fisika dan Biologi
Publisher : Asosiasi Riset Ilmu Pendidikan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/jupenkifb.v1i3.321

Abstract

This study aims to analyze students’ conceptual understanding of hydrocarbons through a literature review utilizing the Three-Tier Multiple Choice Diagnostic Instrument. Hydrocarbons are a fundamental topic in chemistry education that often leads to student misconceptions. The three-tier diagnostic instrument is designed not only to assess students’ cognitive knowledge through correct or incorrect answers but also to explore the reasoning behind their choices, enabling more accurate identification of misconceptions and conceptual understanding. The methodology employed is a literature review examining various scientific sources on the application of this diagnostic tool in teaching hydrocarbon concepts. The findings indicate that the Three-Tier Multiple Choice Diagnostic Instrument is effective in systematically detecting and classifying students’ difficulties and misconceptions. Furthermore, the use of this instrument contributes significantly to developing targeted and data-driven instructional strategies to enhance students’ conceptual mastery in chemistry. The implications of this study highlight the necessity of integrating three-tier diagnostic instruments in the assessment process to support optimal learning outcomes in hydrocarbon material.
Co-Authors Abdul Wahab Pahrun Ahmad Kadir Kilo Ahmat Sudir Umar Aisyah, Sifa Nurul Akram La Kilo Apriyanto Syawal Arfan Arfan Arfan Arfan Arsyad, Muhammad Arif M. Arwin, Muh. Asaria Dakhi Astin Lukum Botutihe, Deasy N. Dewi Budi Purwati Erga Kurniawati Erni Mohamad Fidya, Fidya Haris Lukum HARIS MUNANDAR Haris Munandar Harni Anhar S. Ambololo Hendri Iyabu Hendri Iyabu Hidanurhayati, Hidanurhayati Ika Riyana Tungkagi Ipilo, Sri Rahayu Ishak Isa Jafar La Kilo Julhim S Tangio Julhim S Tangio Julhim S. Tangio Karmila B. Enu Kasman Kasman La Alio La Ode Aman Lasim, Windi Sulistiyani Limbanadi, Sandi Lukman A. R. Laliyo Maksum, M. Junaidi Manaa, Ramayanti N Mardjan Paputungan Marsya Divya Olii Masrid Pikoli Masrina . Moh Musli Malajai Moh. Fajri Langgene Muh. Arwin Musa, Weny A Najmah Najmah Netty Ino Ischak Ni Wayan Desni Nur, Dian Nurhayati Bialangi Olii, Marsya Divya Openhotman, Openhotman Opir Rumape Perry Zakaria Pinangi, Dea Pratiwi Salilung Puriyanto, Edi Rahman, Sapriyaty Rahmawati Hilala Riryn Tahir Sangkota, Vivi Dia Afrianti Sriyanti S Said Suliyana Ibrahim Sumarlin Soleman Suti Anggriani Latief Sutra S Hadis Thayban Thayban Thayban, Thayban Tri Handayani Weny J.A. Musa Wiwin Rewini Kunusa Wiwiyani Wiwiyani Yuszda K Salimi Zulfa K Muslimin