Article Per Year (5 Year)
p-Index From 2020 - 2025
3.701
P-Index
This Author published in this journals
All Journal Pharmaciana: Jurnal Kefarmasian JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Jurnal Penelitian Kesehatan Suara Forikes Belitung Nursing Journal JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Respirologi Indonesia Jurnal Ilmu Kefarmasian Indonesia Indonesian Journal of Cancer Eduvest - Journal of Universal Studies Jurnal Farmasi Indonesia Holistik Jurnal Kesehatan Jurnal Info Kesehatan Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)
Nadia Farhanah Syafhan
Division Of Clinical Pharmacy, Faculty Of Pharmacy, Universitas Indonesia, Depok 16424, West Java, Indonesia | Universitas Indonesia Hospital, Jl. Prof. DR. Bahder Djohan, Pondok Cina, Beji, Depok, West Java 16424, Indonesia
Aerospace Engineering Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

Published : 23 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 23 Documents
Search

 1   2   3 
Pemakaian Obat Nefrotoksik Sebagai Determinan Drug-Induced Acute Kidney Injury (D-AKI) Hadiwati, Rangkay; Andrajati, Retnosari; Syafhan, Nadia Farhanah; Wahono, Dwi Edi
Jurnal Penelitian Kesehatan SUARA FORIKES Vol 15, No 1 (2024): Januari-Maret 2024
Publisher : FORIKES

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33846/sf15130

Abstract

Events related to drug reactions are very difficult to recognize, because they often look like other diseases and many symptoms of drug reactions appear, especially for short drug exposures. Acute Kidney Injury is a condition that affects the structure and function of the kidneys, which is characterized by a sudden decrease in kidney function which causes necrosis of the tubules. The aim of this study was to analyze the prevalence of Drug-Induced Acute Kidney Injury and determine the main risk factors as well as drug data that can influence the increase in serum creatinine levels during treatment. This study implemented a cross-sectional design. The sampling location was the Medical Records section of Gatot Soebroto Army Hospital, with a sample size of 56 patients identified using the Kidney Disease Improving Global Outcomes (KDIGO) criteria and using trigger tools. Data were analyzed using the Chi-square test. The results of the analysis showed that the prevalence of Drug-Induced Acute Kidney Injury in the RSPAD Gatot Soebroto inpatient room was 8.975%-18.527%. Factors that influence the occurrence of Drug-Induced Acute Kidney Injury in the inpatient room were comorbidities (PR = 8.975; 95% CI = 1.317-61.159; p-value = 0.025) and drug interactions (PR = 18.527; 95% CI = 1.727 -177.909; p-value = 0.011). In general, the most widely used nephrotoxic drugs were a combination of >3 types of nephrotoxic drugs, diuretics, NSAIDs, cephalosporins, ARBs, ACEi and chemotherapy drugs. Based on the research results, it was concluded that the use of nephrotoxic drugs was a determinant of Drug-Induced Acute Kidney Injury in the Gatot Soebroto Army Hospital inpatient room.Keywords: kidney disease; Drug-Induced Acute Kidney Injury; nephrotoxic drugs; trigger tools; creatinine ABSTRAK Kejadian yang berhubungan dengan reaksi obat sangat sulit dikenali, karena sering tampak seperti penyakit lain dan banyak gejala reaksi obat yang muncul, terutama untuk paparan obat yang singkat. Acute Kidney Injury adalah salah satu dari kondisi yang mempengaruhi struktur dan fungsi ginjal, yang ditandai dengan penurunan fungsi ginjal secara tiba-tiba yang menyebabkan nekrosis pada tubulus. Tujuan penelitian ini adalah menganalisis prevalensi Drug-Induced Acute Kidney Injury dan menentukan faktor risiko utama serta data obat-obatan yang dapat mempengaruhi peningkatan kadar kreatinin serum selama dirawat. Penelitian ini menerapkan desain cross-sectional. Tempat pengambilan sampel adalah bagian Rekam Medis RSPAD Gatot Soebroto, dengan ukuran sampel adalah 56 pasien yang diidentifikasi dengan menggunakan kriteria Kidney Disease Improving Global Outcomes (KDIGO) dan menggunakan trigger tools. Data dianalisis menggunakan uji Chi-square. Hasil analisis menunjukkan bahwa prevalensi Drug-Induced Acute Kidney Injury di ruang rawat inap RSPAD Gatot Soebroto adalah 8,975%-18,527%. Faktor-faktor yang mempengaruhi terjadinya Drug-Induced Acute Kidney Injury di ruang rawat inap adalah komorbid (PR = 8,975; 95% CI = 1,317-61,159; p-value = 0,025) dan interaksi obat (PR = 18,527; 95% CI = 1,727-177,909; p-value = 0,011). Secara umum obat nefrotoksik yang paling banyak digunakan adalah kombinasi obat nefrotoksik >3 macam, obat diuretik, NSAID, sefalosporin, ARB, ACEi dan obat kemoterapi. Berdasarkan hasil penelitian disimpulkan bahwa pemakaian obat nefrotoksik merupakan determinan dari Drug-Induced Acute Kidney Injury di ruang rawat inap RSPAD Gatot Soebroto.Kata kunci: kidney disease;  Drug-Induced Acute Kidney Injury; obat nefrotoksik; trigger tool; kreatinin
Pendidikan dan Pelatihan untuk Peningkatan Kompetensi Apoteker terkait Telefarmasi: Scoping Review Kartika Citra Dewi Permata Sari; Nisa Maria; Larasati Arrum Kusumawardani; Hindun Wilda Risni; Nadia Farhanah Syafhan; Afina Nur Fauziyyah
JURNAL ILMU KEFARMASIAN INDONESIA Vol 21 No 2 (2023): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v21i2.1487

Abstract

Antihypertensive and antidiabetic drugs in chronic kidney disease (CKD) patients undergoing hemodialyThe high demand for telepharmacy services led to the urge for proper training and education to enhance its quality. This review aimed to assess the implementation and outcomes of telepharmacy training and education programmes. This scoping review was conducted on ScienceDirect, Sage Journal, SpringerLink, and Google Scholar databases using keywords “training” OR “education” AND “telepharmacy,” “training” OR “education” AND “digital competency” AND “pharmacy.” Only English-written articles published between 2000 – 2023, original research and brief report were included in this review. Eight of 171 articles met the criteria and the study’s objectives. Those studies discussed telepharmacy learning programmes for pharmacy students in the USA (5 articles), UAE (2 articles), and Malaysia (1 article). The learning methods included didactic learning, case-based study, simulation/roleplay, and clerkship employing technological tools. Rubrics, quizzes, questionnaires, and objective structured clinical examination (OSCE) were used as assessment methods. All studies reported improved students’ knowledge, perceptions, and telepharmacy competencies. In conclusion, the telepharmacy learning programmes have effectively upgraded students’ knowledge and skills by various methods at every level. However, there remains a considerable need for evidence on suitable training for pharmacists to improve their telepharmacy competencies and service quality.
Medication Adherence, Glycemic Control and Quality of Life in Patients with Type 2 Diabetes Mellitus: a cross-sectional study Eliza, Delila; Syafhan, Nadia Farhanah; Andrajati, Retnosari; Fitriani, Sri Wulandah
JSFK (Jurnal Sains Farmasi & Klinis) Vol 10 No 1 (2023): J Sains Farm Klin 10(1), April 2023
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.10.1.21-27.2023

Abstract

Medication adherence is important in controlling blood sugar levels (HbA1c) in patients with Diabetes Mellitus (DM). Studies on the relationship between medication adherence and blood sugar control on the quality of life (QoL) in Type 2 DM patients are limited in Indonesia. This study aims to assess the relation between medication adherence with blood sugar control and the quality of life of Type 2 DM patients. This study used a cross-sectional design conducted at Universitas Indonesia Hospital. It used Medication Adherence questionnaires and EuroQoL 5D-5L questionnaires to assess patients’ medication adherence and quality of life. This study involved a total of 74 Type 2 DM patients with an average age of 57 ± 10.74 years. Medication adherence with good blood sugar control (HbA1c <7%) showed a significant relationship (p-value <0.05) with COR values of 3.74 (1.21 - 11.6) compared to non-adherent patients. But not on the QoL Index and VAS (Visual Analog Scale) values, where the value is lower in patients with high adherence and good blood sugar control. Factor asscociated with blood sugar controlled were comorbidites and medication adhrence while factor that associated with quality of life were comorbidities, ages, education and employment status
Prevalence and Associated Factors of Drug-Drug Interactions in Hospitalized Diabetic Patients: A Cross-Sectional Study Adil khan, Muhammad; Syafhan, Nadia Farhanah; Andrajati, Retnosari; Wispriyono, Bambang; Noor, Sidra
JSFK (Jurnal Sains Farmasi & Klinis) Vol 11 No 2 (2024): J Sains Farm Klin 11(2), August 2024
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.11.2.86-94.2024

Abstract

Diabetes mellitus is a chronic metabolic condition frequently associated with complications and comorbidities that often require hospitalization for effective management. Such patients are often prescribed multiple medications, which elevate the risk of potential drug-drug interactions (pDDIs). Hence, this study aims to determine the prevalence, severity, common interacting pairs, and factors associated with pDDIs among hospitalized diabetes patients. The study used a retrospective cross-sectional study design conducted at Universitas Indonesia Hospital. Lexicomp® Lexi-InteractTM software was used to analyze and classify possible drug interactions. Logistic regression analysis was used to identify different factors associated with potential DDIs. Of the 200 patients, 89.0% were observed to have pDDIs. A total of 966 interactions were found, of which 75.6% were moderate, 16.2% were minor, and 8.1% were of major severity. Meanwhile, in the risk rating C category, 71.0% were predominant, followed by B and D, 15.0% and 11.0%, respectively. Multivariate regression analysis showed a statistically significant association of pDDIs with 5–8 prescribed medicines (OR=22.8; 95% CI=5.5-94.7; p<0.001), >8 prescribed medicines (OR=64.4; 95% CI=11.3-336.5; p<0.001). The findings of this study revealed that pDDIs are highly prevalent in adult inpatients with diabetes. This emphasizes the critical need for appropriate monitoring and management strategies to reduce pDDIs and their adverse consequences.
Antibiotic Use Evaluation Based on AWaRe Classification in Hospitalized Patients (Intensive and Non-Intensive Care) at Universitas Indonesia Hospital Syafhan, Nadia Farhanah; Sri Wulandah Fitriani; Dinda Bestari Sutantoputri; Nadhila Hasna Hanifah; Adityo Susilo
JSFK (Jurnal Sains Farmasi & Klinis) Vol 11 No 3 (2024): J Sains Farm Klin 11(3), December 2024
Publisher : Fakultas Farmasi Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jsfk.11.3.161-168.2024

Abstract

Antibiotic stewardship program has been largely implemented to reduce antibiotic resistance rates. The present study aimed to evaluate antibiotic use based on the AWaRe classification using the ATC/DDD method and Drug Utilization 90% (DU 90%). This analytical descriptive study used a cross-sectional study design and retrospective data collection obtained using a total sampling technique and processed using Microsoft Excel. The sample for this study involved data from inpatients aged ≥ 18 years at Universitas Indonesia Hospital who had been prescribed antibiotics from 1 January - 31 December 2022. Data from patients who only received topical antibiotic or antibiotics without a DDD standard value from WHO, or patients who had incomplete medical record data were excluded from the study. The results of this study indicated that the total use of antibiotics was 427.85 DDD/100 patient-days. Based on the AWaRe (Access, Watch, Reserve) classification, the Watch class became the most frequently used antibiotic group, followed by the Access and Reserve classes. The 90% DU segment was mostly composed of third-generation cephalosporin group and fluoroquinolones which were included in the Watch class. From the result of this study, to optimally reduce resistance rates, antibiotic stewardship programs need to run continuously.
Assessment of medication-related liver and kidney impairment in admitted patients in Depok, Indonesia: an observational study employing the Naranjo algorithm Syafhan, Nadia Farhanah; Aldora, Ghea Shafa; Kamila, Shinta
Pharmaciana Vol. 15 No. 1 (2025): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v15i1.29012

Abstract

Liver and kidney impairment caused by medications represents serious side effects that may extend hospital stays and increase the risk of patient death. Implementing strategies to recognize, document, and analyze cases of patient harm related to drug use is crucial for medicines optimization. This study aimed to evaluate the prevalence of medication-related liver and kidney impairment among hospitalized patients, while also identifying the specific medication categories implicated. A retrospective review of patient records was conducted at Universitas Indonesia Hospital (Depok, Indonesia), focusing on adult patients diagnosed with liver or kidney impairment during their 2021 hospital admission. The Naranjo algorithm was applied to assess the likelihood that these injuries were caused by medications. Among the 4,273 admitted patients, it was found that 1.01% experienced medication-related liver impairment (MRLI), while 0.77% experienced medication-related kidney impairment (MRKI). The most common medications associated with liver impairment were antibiotics (31.58%), cardiovascular medications (24.21%), pain relievers (14.74%), anti-ulcer medications (11.58%), antiviral medications (8.42%), antiemetics (8.42%), and antidiabetic medications (1.05%). In contrast, kidney disease was primarily linked to diuretics (29.76%), antibiotics (21.43%), ACE inhibitors/ARBs (21.43%), antiviral medications (9.52%), and NSAIDs (7.14%). Importantly, there was no statistically significant correlation between the occurrence of MRLI or MRKI and factors such as gender, age, body mass index (BMI), or the presence of other health conditions (p > 0.05). These findings underscore the need for heightened awareness regarding the potential for medication-related impairments in hospitalized patients and suggest that careful monitoring of medication use is essential to mitigate these risks.
Pengaruh Faktor Risiko terhadap Kejadian Peningkatan Kadar Enzim Transaminase pada Pasien Covid-19 dengan Terapi Tocilizumab Nasution, Izza Aulia Rizqika; Andrajati, Retnosari; Syafhan, Nadia Farhanah; Imaniar, Rania
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 15 No. 1 (2023): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (398.476 KB) | DOI: 10.35617/jfionline.v15i1.137

Abstract

Abstract: Tocilizumab is an anti-IL-6 which is recommended as cytokine release syndrome therapy in the treatment of Covid-19. One of the side effects of tocilizumab that can occur is hepatotoxicity, from mild elevated transaminases to severe drug-induced liver injury (DILI). Currently, research related to tocilizumab hepatotoxicity and the risk factors affecting Covid-19 patients is limited and still needs to conduct. This research is an observational study with cross-sectional design. Data collection was carried out retrospectively using secondary data obtained from medical records department, patients with Covid-19 at Universitas Indonesia Hospital in 2020-2021. Patients confirmed with positive Covid-19 receiving Tocilizumab therapy in medical record were included in this study. Patient demographics, clinical diagnoses, laboratory examinations, history of others medication were also reviewed. Patients with less than 18 years old, incomplete medical record data, and referred to other hospitals were excluded. The sampling technique used was total sampling, namely all patients who met the inclusion criteria were taken as subject in this research. Chi-square test was used to analyze the relationship between each risk factors and the incidence of elevated transaminases. The results of Chi-square test showed that several risk factors significantly increased the incidence of elevated transaminases in patients given tocilizumab therapy, including age, obesity, diabetes mellitus, and ceftriaxone as antibiotic therapy.
The Implementation of Telepharmacy in Bangka Belitung Islands Province Rachmawati Felani Djuria; Retnosari Andrajati; Nadia Farhanah Syafhan; Bambang Wispriyono
JURNAL INFO KESEHATAN Vol 21 No 3 (2023): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Politeknik Kesehatan Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol21.Iss3.1059

Abstract

Telepharmacy is a telemedicine health service in the pharmaceutical sector that uses telecommunications to assist patients located far away during the Covid-19 pandemic. Furthermore, professional organizations are responsible for continuously providing information to pharmacists, ensuring they stay updated with the latest developments in the field. Mobile applications have emerged as the primary medium through which information can be accessed. Therefore, this research aimed to determine the implementation of telepharmacy in the Bangka Belitung Islands Province using observational research with a qualitative approach. The participants comprised a total of 11 individuals and the technique employed was purposive sampling. Subsequently, the collected data were subjected to analysis using the Miles and Huberman model. The results showed that the utilization of telepharmacy commenced within Bangka Belitung Islands Province and the community pharmacy service implemented the concept in the form of Drug Information Services, drug consultation or patient counseling, and prescription services through e-prescribing. Additionally, field observations highlighted the presence of services such as home delivery of medicines, patient education, and online non-cash payments. The implementation of telepharmacy within hospitals remains absent, despite the widespread adoption of digital services facilitated by the SIMRAS application. Pharmacists also ensured the administrative compliance of their colleagues through the utilization of the SIAP application. The preliminary stages of the implementation commenced in the Bangka Belitung Islands Province.  
Evaluation of drug services based on prescription indicators and patient care according to who at the hospital general practitioner (GP) outpatient clinic in Depok, Indonesia Syafhan, Nadia Farhanah; Risni, Hindun Wilda; Salsabila, Azzahra Fahira; Purnama Putri, Raden Jacinda Yasmin; Prasetyaningrum, Marchen
JURNAL ILMU KEFARMASIAN INDONESIA Vol 23 No 1 (2025): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v23i1.1609

Abstract

The World Health Organization (WHO) has developed prescription and patient care indicators, accompanied by optimal benchmarks, aimed at promoting the rational and optimal medicine use. This study aims to evaluate drug services utilizing WHO prescription and patient care indicators at the hospital General Practitioner (GP) outpatient clinic. The research was conducted retrospectively for prescription indicators, consisting of 1505 prescriptions totaling 4647 medication items administered for 804 individuals between January and December 2022. Prospective data collection to evaluate patient care was conducted from April to May 2023. Evaluation of WHO prescription indicators yielded the following results: the average number of drugs prescribed per patient was 3.09 ± 2.00; the percentage of drug prescribed by generic drug names was 47.47%; the percentage of antibiotic prescriptions was 5.46%; the percentage of injectable drug prescriptions was 6.80%; and the percentage of prescriptions in accordance with the national formulary was 75.91%. The percentages of antibiotic and injectable drug prescriptions met the optimal WHO prescription values. In terms of patient care, the results showed that the average duration of a medical consultation was 12.44±8.1 minutes, the average duration of a drug dispensing was 45.65±28.8 minutes, 96.25% of the drugs were dispensed appropriately, 100% of the drugs were labeled adequately, and 78.78% of the patients were knowledgeable. Age (p=0.111) and gender (p=0.075) showed no significant correlation with patient knowledge. There was a significant relationship between education level (p=0.014) and patient knowledge. Prescription and patient care indicators are aspects of improvement to meet the optimal benchmarks according to WHO standards.
Relationship of Cognitive Function on Medication Adherence and Clinical Outcomes of Geriatric Patients with Diabetic Neuropathy Fauzi, Muhamad Andhika; Syafhan, Nadia Farhanah; Habibie, Taufan Harun
Eduvest - Journal of Universal Studies Vol. 5 No. 2 (2025): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i2.44735

Abstract

Diabetic neuropathy is a common complication of diabetes mellitus that significantly impacts quality of life and is also prone to cognitive decline exacerbated by diabetes complications. Medication adherence has been shown to slow or prevent cognitive decline. Neuropathy symptoms, neuropathic pain, and sensory disturbances can worsen cognitive function. This study aimed to assess the relationship between cognitive function and medication adherence, as well as clinical outcomes of neuropathy symptoms in geriatric patients with diabetic neuropathy. This observational cross-sectional study involved 217 geriatric patients at RSUD Tebet from June to September 2024. Cognitive function was assessed using the MoCA-Ina questionnaire, and adherence was measured through questionnaires, medical records, and direct observation (MARS-5, MPR, and Pill Count) as well as DNS scoring to assess clinical outcomes of neuropathy symptoms. This study found that women (71,5%) were more likely to experience cognitive decline than men (28,5%). The study found that medication adherence varied by method. Triangulation showed 64.6% non-adherence in cognitive decline versus 35.4% in normal function (OR 1.774, 95% CI: 1.001-3.144). Caregiver presence significantly affected adherence (p=0.011), with a 2.8 times higher risk of non-adherence and a 2.4 times higher risk of neuropathy symptoms in patients without caregivers.
Co-Authors Abu Rachman Adil khan, Muhammad Aditya Wirawan Adityo Susilo, Adityo Afina Nur Fauziyyah AGUSDINI BANUN SAPTANINGSIH Aldora, Ghea Shafa Amarila Malik Andi Utari Prasetya Ningrum Andrajati, Retnosari Ariesa Oktamauri Azizahwati Bambang Karsono Bambang Wispriyono Chairunnisa, Dian Fitri Deli Marteka Delila Eliza DENNI JOKO PURWANTO, DENNI JOKO Dinda Bestari Sutantoputri Djuria, Rachmawati Felani Eliza, Delila Elsa Vera Denida Purba Farmasita Budiastuti, Rizky Fauzi, Muhamad Andhika Habibie, Taufan Harun Hadijah Tahir Hadiwati, Rangkay Hindun Wilda Risni Hindun Wilda Risni Imaniar, Rania Imanuel Sianipar Ingrid Faustine July Kamila, Shinta Kartika Citra Dewi Permata Sari Kartika Citra Dewi Permata Sari Kusumawardani, Larasati Arrum Meiliani Shara Suria L MUTIARA JEANY RAHAYU PERTIWI Nadhila Hasna Hanifah Nasution, Izza Aulia Rizqika Nisa Maria Noor, Sidra Prasetyaningrum, Marchen Pukovisa Prawiroharjo Pukovisa Prawiroharjo, Pukovisa Purnama Putri, Raden Jacinda Yasmin Rachman, Abu Rachmawati Felani Djuria Rani Sauriasari Rani Sauriasari Rani Sauriasari, Rani Retnosari Andrajati Retnosari Andrajati Retnosari Andrajati Retnosari Andrajati Retnosari Andrajati Retnosari Andrajati Risni, Hindun Wilda Salsabila, Azzahra Fahira Santi Purna Sari Sri Wulandah Fitriani Sri Wulandah Fitriani Sri Wulandah Fitriani, Sri Wulandah Vriona Ade Maenkar Wahono, Dwi Edi Yahdiana Harahap