Nadia Farhanah Syafhan
Division Of Clinical Pharmacy, Faculty Of Pharmacy, Universitas Indonesia, Depok 16424, West Java, Indonesia | Universitas Indonesia Hospital, Jl. Prof. DR. Bahder Djohan, Pondok Cina, Beji, Depok, West Java 16424, Indonesia

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Cognitive Function in Type 2 Diabetes Mellitus Patients Taking Metformin and Metformin-Sulfonylurea Rachman, Abu; Sauriasari, Rani; Syafhan, Nadia Farhanah; Prawiroharjo, Pukovisa; Risni, Hindun Wilda
Kesmas Vol. 17, No. 4
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The most prescribed antidiabetic drugs in Indonesian primary health care are metformin or a combination of metformin and sulfonylurea. Studies on metformin have shown various impacts on cognitive decline in patients with type 2 diabetes mellitus, whereas sulfonylurea has been shown to reduce this impact. This study aimed to compare the impacts of metformin and metformin-sulfonylurea on cognitive function and determine what factors affected it. This cross-sectional study was conducted at Pasar Minggu Primary Health Care involving 142 type 2 diabetes mellitus patients taking metformin or metformin-sulfonylurea for > 6 months and aged > 36 years. Cognitive function was assessed using the validated Montreal Cognitive Assessment Indonesian version. The effects of metformin and metformin-sulfonylurea on cognitive decline showed no significant difference, even after controlling for covariates (aOR = 1.096; 95% CI = 0.523–2.297; p-value = 0.808). Multivariate analysis showed age (OR = 4.131; 95% CI = 1.271–13.428; p-value = 0.018) and education (OR = 2.746; 95% CI = 1.196–6.305; p-value = 0.017) affected cognitive function. Since a lower education and older age are likely to cause cognitive decline, health professionals are encouraged to work with public health experts to address these risk factors for cognitive function.
Pendidikan dan Pelatihan untuk Peningkatan Kompetensi Apoteker terkait Telefarmasi: Scoping Review Permata Sari, Kartika Citra Dewi; Maria, Nisa; Kusumawardani, Larasati Arrum; Risni, Hindun Wilda; Syafhan, Nadia Farhanah; Fauziyyah, Afina Nur
JURNAL ILMU KEFARMASIAN INDONESIA Vol 21 No 2 (2023): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v21i2.1487

Abstract

Antihypertensive and antidiabetic drugs in chronic kidney disease (CKD) patients undergoing hemodialyThe high demand for telepharmacy services led to the urge for proper training and education to enhance its quality. This review aimed to assess the implementation and outcomes of telepharmacy training and education programmes. This scoping review was conducted on ScienceDirect, Sage Journal, SpringerLink, and Google Scholar databases using keywords “training” OR “education” AND “telepharmacy,” “training” OR “education” AND “digital competency” AND “pharmacy.” Only English-written articles published between 2000 – 2023, original research and brief report were included in this review. Eight of 171 articles met the criteria and the study’s objectives. Those studies discussed telepharmacy learning programmes for pharmacy students in the USA (5 articles), UAE (2 articles), and Malaysia (1 article). The learning methods included didactic learning, case-based study, simulation/roleplay, and clerkship employing technological tools. Rubrics, quizzes, questionnaires, and objective structured clinical examination (OSCE) were used as assessment methods. All studies reported improved students’ knowledge, perceptions, and telepharmacy competencies. In conclusion, the telepharmacy learning programmes have effectively upgraded students’ knowledge and skills by various methods at every level. However, there remains a considerable need for evidence on suitable training for pharmacists to improve their telepharmacy competencies and service quality.
The Impact of Appropriateness of Empirical Antibiotic in Hospitalized Pneumonia Patients on Clinical Outcomes and Length of Stay Thoriq, Syahrul Fath; Syafhan, Nadia Farhanah; Aziz, Muhammad Luthfi
Eduvest - Journal of Universal Studies Vol. 4 No. 11 (2024): Journal Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v4i11.1450

Abstract

Pneumonia is the leading cause of morbidity and mortality in adults worldwide. The incidence of pneumonia is still very high in Indonesia. The main standard therapy for pneumonia is empirical antibiotic administration.  The purpose of this study was to determine whether there was an impact of the appropriateness of empirical antibiotics therapy on clinical outcomes and length of stay of non-ICU pneumonia patients at X Hospital in Jakarta. This study used a retrospective cohort design to determine the appropriateness of empirical antibiotics use in non-ICU pneumonia patients. The samples taken are all non-ICU pneumonia patients during the period January 2022 – December 2023 who met the inclusion criteria. Data analysis was carried out descriptively for patient characteristics, drug use profile, and the appropriateness of empirical antibiotic. A chi-square test was used to determine the impact of appropriateness of empirical antibiotics on clinical outcomes and length of stay. The appropriateness of empirical antibiotics obtained 59,5% (173 regimens) met category 0 (appropriate), and 40,5% (118 regimens) met category I-VI (inappropriate). Based on the results, there is an impact of the appropriateness of empirical antibiotics on clinical outcomes (P = 0,000; RR =1,916; 95% CI = 1,558 – 2,357), and impact of of the appropriateness of empirical antibiotics on length of stay (P = 0,002; RR =1,410; 95% CI = 1,126 – 1,765). The analysis's results showed that the impact of appropriateness of empirical antibiotic on clinical outcomes and length of stay of non-ICU inpatients with pneumonia at X Hospital in Jakarta.
Systematic Review: The Impact of Antimicrobial Stewardship Program Implementation in Hospital Intensive Care Units Candra, Tifany Maulida; Syafhan, Nadia Farhanah; Kurniasih, Fransisca Dhani
Eduvest - Journal of Universal Studies Vol. 4 No. 11 (2024): Journal Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v4i11.1467

Abstract

Antimicrobial resistance represents a significant challenge in clinical settings, particularly in intensive care units (ICUs). The incidence of antimicrobial resistance in the ICUs has reached 30% of all hospital patients. Furthermore, over 71% of patients on the unit were using antibiotics. Consequently, infections contribute substantially to the elevated mortality and morbidity rates in patients with critical status. The Antimicrobial Stewardship Program (ASP) is a program that refers to a multidisciplinary approach to optimize the appropriate use of antimicrobials. This systematic review aims to identify ASP policies implemented in hospital ICUs, utilizing various parameters for assessment. This systematic review was conducted using PubMed, Scopus, Google Scholar, and the Cochrane Database of Systematic Reviews, focusing on publications from January 1, 2015, to June 1, 2024. A comprehensive review of 4,419 articles identified 12 studies that met the inclusion and exclusion criteria. The primary goal of ASP is to enhance the appropriateness of antimicrobial use, ensuring accurate prescribing practices in terms of indication, antimicrobial selection, route of administration, and therapy duration. The outcomes of ASP implementation are evaluated based on decreased in antimicrobial use, increased in the number of recommendations, decreased in treatment costs, and a decrease in multidrug-resistant organism (MDRO) incidence. Although numerous articles have provided positive results regarding the implementation of ASP in ICU settings, there remains a need for extensive and structured research to validate these findings comprehensively.
The Implementation of Telepharmacy in Bangka Belitung Islands Province Djuria, Rachmawati Felani; Andrajati, Retnosari; Syafhan, Nadia Farhanah; Wispriyono, Bambang
JURNAL INFO KESEHATAN Vol 21 No 3 (2023): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol21.Iss3.1059

Abstract

Telepharmacy is a telemedicine health service in the pharmaceutical sector that uses telecommunications to assist patients located far away during the Covid-19 pandemic. Furthermore, professional organizations are responsible for continuously providing information to pharmacists, ensuring they stay updated with the latest developments in the field. Mobile applications have emerged as the primary medium through which information can be accessed. Therefore, this research aimed to determine the implementation of telepharmacy in the Bangka Belitung Islands Province using observational research with a qualitative approach. The participants comprised a total of 11 individuals and the technique employed was purposive sampling. Subsequently, the collected data were subjected to analysis using the Miles and Huberman model. The results showed that the utilization of telepharmacy commenced within Bangka Belitung Islands Province and the community pharmacy service implemented the concept in the form of Drug Information Services, drug consultation or patient counseling, and prescription services through e-prescribing. Additionally, field observations highlighted the presence of services such as home delivery of medicines, patient education, and online non-cash payments. The implementation of telepharmacy within hospitals remains absent, despite the widespread adoption of digital services facilitated by the SIMRAS application. Pharmacists also ensured the administrative compliance of their colleagues through the utilization of the SIAP application. The preliminary stages of the implementation commenced in the Bangka Belitung Islands Province.  
Evaluation of drug services based on prescription indicators and patient care according to who at the hospital general practitioner (GP) outpatient clinic in Depok, Indonesia Syafhan, Nadia Farhanah; Risni, Hindun Wilda; Salsabila, Azzahra Fahira; Purnama Putri, Raden Jacinda Yasmin; Prasetyaningrum, Marchen
JURNAL ILMU KEFARMASIAN INDONESIA Vol. 23 No. 1 (2025): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v23i1.1609

Abstract

The World Health Organization (WHO) has developed prescription and patient care indicators, accompanied by optimal benchmarks, aimed at promoting the rational and optimal medicine use. This study aims to evaluate drug services utilizing WHO prescription and patient care indicators at the hospital General Practitioner (GP) outpatient clinic. The research was conducted retrospectively for prescription indicators, consisting of 1505 prescriptions totaling 4647 medication items administered for 804 individuals between January and December 2022. Prospective data collection to evaluate patient care was conducted from April to May 2023. Evaluation of WHO prescription indicators yielded the following results: the average number of drugs prescribed per patient was 3.09 ± 2.00; the percentage of drug prescribed by generic drug names was 47.47%; the percentage of antibiotic prescriptions was 5.46%; the percentage of injectable drug prescriptions was 6.80%; and the percentage of prescriptions in accordance with the national formulary was 75.91%. The percentages of antibiotic and injectable drug prescriptions met the optimal WHO prescription values. In terms of patient care, the results showed that the average duration of a medical consultation was 12.44±8.1 minutes, the average duration of a drug dispensing was 45.65±28.8 minutes, 96.25% of the drugs were dispensed appropriately, 100% of the drugs were labeled adequately, and 78.78% of the patients were knowledgeable. Age (p=0.111) and gender (p=0.075) showed no significant correlation with patient knowledge. There was a significant relationship between education level (p=0.014) and patient knowledge. Prescription and patient care indicators are aspects of improvement to meet the optimal benchmarks according to WHO standards.