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All Journal Indonesian Journal of Cancer Chemoprevention Martabe : Jurnal Pengabdian Kepada Masyarakat Jurnal Ilmu Kesehatan ad-Dawaa : Journal of Pharmaceutical Sciences HERBAPHARMA : Journal of Herb Farmacological Jurnal Kesehatan Tambusai Journal of Fundamental and Applied Pharmaceutical Science Medimuh : Jurnal Kesehatan Muhammadiyah Indonesian Community Journal Jurnal Ilmiah Bakti Farmasi Medical Sains : Jurnal Ilmiah Kefarmasian SITAWA : Jurnal Farmasi Sains dan Obat Tradisional Borobudur Pharmacy Review Ekalaya: Jurnal Pengabdian Kepada Masyarakat Indonesia Sinteza CERATA Journal Of Medicine And Health Sciences (Medisci) Medimuh : Jurnal Kesehatan Muhammadiyah Medical Sains : Jurnal Ilmiah Kefarmasian Baktimu : Jurnal Pengabdian Kepada Masyarakat Indonesian Journal of Pharmacology and Therapy Baktimu : Jurnal Pengabdian Kepada Masyarakat Medimuh : Jurnal Kesehatan Muhammadiyah
Hadi, Ismanurrahman
Universitas Muhammadiyah Ahmad Dahlan, Indonesia
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Description of Mother’s Knowledge and Adherence to Use of Helminthic Drugs in Kuwaluhan Village, Magelang Regency, Central Java Amanda, Shalma Risqi; Haresmita, Perdana Priya; Wardani, Arief Kusuma; Hadi, Ismanurrahman
Jurnal Ilmu Kesehatan Vol 11 No 1 (2023): Jurnal Ilmu Kesehatan
Publisher : Universitas Muhammadiyah Kalimantan Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30650/jik.v11i1.3626

Abstract

Worm infection has become public health issue with the highest prevalence in children under the age of five and elementary school-aged children. The children have difficulty maintaining the hygienist, especially when they are playing. This study aims to describe the level of knowledge and mothers’ adherence to the use of helminthic drugs in Kuwaluhan Village, Magelang Regency. This research used a descriptive study with both a survey method and a cross-sectional approach. The purposive sampling technique was used, while the questionnaire was distributed to mothers with children under the age of five and elementary school-age children in Kuwaluhan Village RW 2, Magelang Regency, in December 2022. The results showed that the level of knowledge of mothers in Kuwaluhan Village RW 2, Magelang Regency, regarding the use of helminthic drugs out of a total of 74 mothers indicated that 33 respondents (44.59%) had good knowledge, 29 respondents (39.19%) had sufficient knowledge, and as many as 12 respondents (16.22%) had less knowledge. Meanwhile, at the adherence level, respondents were categorized as having high adherence by 1 respondent (1.35%), medium adherence by 73 respondents (98.65%), and low adherence by 0 respondents (0%). Based on these results, most of the mothers in Kuwaluhan RW 2, Magelang Regency have good knowledge and have a medium level of adherence to using helminthic drugs for children.
Telaah Potensi Antivirus Mitraginin terhadap Protease 3CLpro SARS-CoV-2 dengan Pendekatan Molecular Docking Setiawansyah, Arif; Susanti, Gita; Hidayati, Nurul; Gemantari, Baiq Maylinda; Alrayan, Reza; Hadi, Ismanurrahman; Luthfiana, Dewi; Hasanah, Nurul
Sinteza Vol. 4 No. 2 (2024): August
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/sinteza.v4i2.25634

Abstract

SARS-CoV-2 is a novel coronavirus identified as a major caused of COVID-19. COVID-19 can be prevented and managed by preventing the SARS-CoV-2 infection through inhibition of SARS-CoV-2 main protease. Mitragynine is one of the major compounds found in Mitragyna speciosa leaves that has the potential to be developed as an anti-COVID-19 agent. This research was implemented to evaluate that potential by observing the molecular interaction of mitragynine with the essential amino acid residues of SARS-CoV-2 3CLpro. The study was undertaken by in silico method via molecular docking approach using Autodock 4.2. The potential of mitragynine in inhibiting the SARS-CoV-2 main protease was justified based on its free binding energy and Ki. The result revealed that mitragynine exhibited a lower free binding energy and Ki than remdesivir with the free binding energy and Ki value of -7.80 kcal/mol dan 1.92 µM dan -7.41 kcal/mol dan 3.72 µM, respectively. This concluded that mitragynine has the potential as a SARS-CoV-2 main protease inhibitor with the affinity was better than remdesivir. However, further in vitro research must be carried out to prove this potential. 
Pengaruh Variasi Minyak Kelapa Terhadap Karakteristik Fisik Sabun Padat Minyak Atsiri Sereh Wangi Listiyani, Oktavia; Wardani, Arief Kusuma; Yuliastuti, Fitriana; Hadi, Ismanurrahman
SITAWA : Jurnal Farmasi Sains dan Obat Tradisional Vol. 5 No. 1 (2026): SITAWA : Jurnal Farmasi Sains dan Obat Tradisional
Publisher : LPPM Akademi Farmasi Imam Bonjol Bukittinggi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62018/sitawa.v5i1.164

Abstract

Sabun padat merupakan produk pembersih yang semakin diminati karena efektif dan ekonomis. Salah satu bahan alami potensial dalam pengembangan sabun padat adalah minyak atsiri sereh wangi sebagai antibakteri, serta minyak kelapa yang berperan dalam pembentukan busa sabun. Penelitian ini bertujuan untuk mengevaluasi pengaruh variasi konsentrasi minyak kelapa terhadap karakteristik fisik sabun padat berbahan aktif minyak atsiri sereh wangi. Penelitian dilakukan secara eksperimental dengan tiga formula berbeda (F1: 18%, F2: 16%, F3: 14% minyak kelapa) dan konsentrasi minyak atsiri tetap 2%. Evaluasi dilakukan terhadap parameter organoleptik, pH, tinggi busa, dan stabilitas busa selama penyimpanan empat minggu. Hasil menunjukkan bahwa F1 memiliki kestabilan bentuk dan warna terbaik, sementara F3 menghasilkan tinggi dan stabilitas busa paling konsisten. Seluruh formula berada dalam rentang pH sesuai SNI 3532:2021. Kesimpulannya, variasi konsentrasi minyak kelapa memengaruhi karakteristik fisik sabun, dan formulasi F1 dinilai paling optimal dalam mendukung pembentukan dan kestabilan busa.
Co-Authors Achmad Dinoto Ade Irawan Ade Irawan Alfayyasy, Akhmad Irfan Alrayan, Reza Amanda, Shalma Risqi Amelia Zannah Andi Suhendi Antika Mardhotillah Meilian Arif Setiawansyah Arsul, Muhammad Ikhlas Aulia, Diva Ayu Puspitasari, Ayu Ayu Zakkiyah Azhari, Samsudin Baiq Maylinda Gemantari Dadan Hidayattullah Dewi Luthfiana Didik Setiawan Dwi Lestari Edy Meiyanto Efirani, Like Efriani, Like Ema Damayanti Febriansah , Rifki Fitriana Yuliastuti Flori Sindi Agwiana Gita Susanti, Gita Haq, Mailatul Ilal Heni Lutfiyati, Heni Hidajah Rachmawati Ikhlas Arsul, Muhammad JAKA WIDADA Joko Priyanto Wibowo Khoirun Nisa Like Efriani Like Efriani Listiyani, Oktavia Luthfiana, Dewi MARIAM ULFAH Mariam Ulfah MARIAM ULFAH ULFAH Muhamad Rifki Purnama Mustofa Mustofa Nur Aprillia Martalina Nurfazera, Asya Nurlutfiana, Deby Nurul Hasanah Nurul Hidayati oliviana, Resya Perdana Priya Haresmita Perdana Priya Haresmita, Perdana Priya Prihatiningsih, Sherly Purnama, Muhamad Rifki Putra, Teguh Adiyas Reza Alrayan Ria Utami, Primanitha Riris Istighfari Jenie Rohmatika, Nirma Shinta, Tiara Aries Silviyani, Amerta Supandi Tuzzahra, Fatimah Ulfah, Mariam Wardani, Arief Kusuma Wismayani, Leni Wiwin Widayanti