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All Journal Jurnal Teknologi Dan Industri Pangan Jurnal Teknik Industri Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Jurnal AGROTEKNOLOGI Jurnal Kedokteran Brawijaya The Journal of Experimental Life Sciences (JELS) Alchemy : Journal of Chemistry Agrointek Journal of Innovation and Applied Technology Jurnal Pangan dan Agroindustri Jurnal Keteknikan Pertanian Tropis dan Biosistem Jurnal Teknologi Pertanian agriTECH JPPM (Jurnal Pengabdian dan Pemberdayaan Masyarakat) Advances in Food Science, Sustainable Agriculture and Agroindustrial Engineering (AFSSAAE) Berkala Penelitian Hayati Jurnal Riset Teknologi Pangan Dan Hasil Pertanian (RETIPA)

SIMON BAMBANG WIDJANARKO

Jurusan Teknologi Hasil Pertanian Fakultas Teknologi Pertanian Universitas Brawijaya

Author-ID : 415979

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Electrical & Electronics Engineering Energy Engineering Environmental Science Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Neuroscience Public Health Social Sciences

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Extraction and Stability of Betacyanin from Blood Leaf (Study on Water to Ethanol Ratio and Extraction Temperature) Khuluq, Ahmad Dhiaul; Widjanarko, Simon Bambang; Murtini, Erni Sofia
Jurnal Teknologi Pertanian Vol 8, No 3 (2007)
Publisher : Fakultas Teknologi Pertanian Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (216.148 KB)

The aim of this research was to know the temperatureâ€™s influence and the solvent comparison (water:ethanol) on the betacyanin extract properties from blood leaf. The research was also aimed to know the stability of betacyanin extract toward temperature, pH, oxidant, and light of the best treatment. This research was conducted in two factorial randomized block design. The first factor was extraction temperature (4oC, 30oC and 60oC) and the second factor was water to ethanol ratio (8:2, 5:5, and 2:8 (v/v). Each treatment combination was conducted in triplication. The result of this research was analyzed using ANOVA, followed by 5% LSD test. If it had interaction, it would be continued by DMRT 5% test. The best treatment was tested using De Garmo effectiveness index. The best characteristic of extract was obtained from the water to ethanol ratio of 5:5 and extraction temperature of 30oC. Extract had physic-chemical properties as follows: betacyanin content of 45,81 mg/100 g, yield of 81,05%, ethanol residue of 0,099%, pH of 6,68, and color intensity L* of 24,4; a* of 4,7; and b* of 7,9. The stability of extract decreased as well as the increasing of heating temperature, oxidant concentration (H2O2), and duration of lamp rays radiation, and the extract stability increased at pH 5Keywords: Betacyanin, solvent, temperature, stability

PENGARUH METODE PERENDAMAN KEDELAI (Glycine max) TERHADAP KARAKTERISTIK PEKTIN Prabowo, Ivy Dian Puspitasari; Widjanarko, Simon Bambang; Yuwono, Sudarminto Setyo
Jurnal Teknologi Pertanian Vol 19, No 2 (2018)
Publisher : Fakultas Teknologi Pertanian Universitas Brawijaya

ABSTRAKPerendaman kedelai dapat mempengaruhi rendemen dan derajat esterifikasi dari pektin. Setiap industri tempe memiliki metode perendaman kedelai yang berbeda-beda. Air rendaman kedelai dan kulit ari kedelai merupakan produk samping dari industri tempe yang berpotensi sebagai bahan baku pembuatan pektin. Tujuan dari penelitian ini adalah menentukan metode perendaman kedelai yang terbaik untuk menghasilkan rendemen dan derajat esterifikasi pektin yang tinggi, sekaligus mengetahui kadar asam galakturonat. Pengujian dilakukan secara RAK (Rancangan Acak Kelompok) dengan faktor metode perendaman kedelai yaitu (1) kedelai direbus 30 menit, (2) kedelai direndam 18 jam kemudian direbus 30 menit, dan (3) kedelai direbus 30 menit kemudian direndam 18 jam. Hasil penelitian menunjukan kedelai yang direbus 30 menit kemudian direndam 18 jam merupakan perlakuan yang paling baik karena memiliki rendemen (1.12 Â± 0.03%) dan derajat esterifikasi (56.33 Â± 1.96%) yang paling tinggi. Pektin dari penelitian ini memiliki kadar asam galakturonat sebesar 22.45 Â± 0.84%. Industri tempe dapat menerapkan penelitian ini untuk mengurangi limbah padat dan limbah cair menjadi pektin.Â ABSTRACTSoaking soybean may affect the yield and degree of esterification of pectin. Each tempe industry has different soybean soaking methods. Soaking soybean water and soybean hull are a by-product of tempe industry which has potential as raw material for pectin making. The purpose of this research is to determine the best soybean soaking method to produce high yield and degree of esterification, simultaneously to determine galacturonic acid content. The experiments used RAK (Randomized Block Design) with factor of soybeans soaking method. The methods were: (1) Soybean boiled for 30 minutes, (2) Soybeans soaked 18 hours then boiled 30 minutes, and (3) Soybean boiled 30 minutes then soaked 18 hours. The results showed that soaked soybeans 30 minutes and then soaked 18 hours is the best treatment because it has the highest yield (1.12 Â± 0.03%) and degree of esterification (56.33 Â± 1.96%). The pectin of this soybean has 22.45 Â± 0.84% of galacturonic acid. Tempe industry can apply this research to reduce its solid and liquid waste to be pectin

Optimasi Produksi Tepung Porang dari Chip Porang Secara Mekanis dengan Metode Permukaan Respons Faridah, Anni; Widjanarko, Simon Bambang; Sutrisno, Aji; Susilo, Bambang
Jurnal Teknik Industri Vol 13, No 2 (2012): Agustus
Publisher : Department Industrial Engineering, University of Muhammadiyah Malang

Porang Tuber (Amorphophallus oncophyllus) has high Glucomanan content which is very useful in food and non food industry as well as in medical industry. The only main problem in development of porang flour is its Calcium Oxalate content that stipulates irritation (itchiness) and health disorder. Optimization study of diminution (reduction) content of Calcium Oxalate during mechanical grinding process using stamp mill and blowing fractionation. Optimization was performed by applying Response Surface Model (RSM), central composite model. Three variables i.e. weight of porang chip, grinding time and grinding speed were studied in order to study the Calcium Oxalate content as a response. Response model obtained was quadratic which was acquired at 1.3 kg porang optimum weight; grinding time 17.4â€™8â€; and grinding speed at 19,23 rpm. Optimum Calcium content has been predicted at 0.2978% which was 0.3% in actual, decrease 92,12%Â

OPTIMALISASI FUNGSI PIGMEN BUNGA MAWAR SORTIRAN SEBAGAI ZAT PEWARNA ALAMI DAN BIOAKTIF PADA PRODUK INDUSTRI Saati, Elfi Anis; RRD, Theovilla; Widjanarko, Simon Bambang; Aulanni'am, A
Jurnal Teknik Industri Vol 12, No 2 (2011): Agustus
Publisher : Department Industrial Engineering, University of Muhammadiyah Malang

The roses known to contain anthocyanins pigments and as a bioactive compound which can act as free radical catcher material. When harvest season arrives in number will be very abundant. Flowers sorting which can decrease the selling price can be processed in the form of natural dyes for food, cosmetics and medicines / herbs. The purpose of this study is to know applications rose to the quality of some industrial products. The experiment was conducted in (fresh, 2 and 4 days), that performed using randomized block design. Phase II is the application of pigment products of red roses on some industrial products (ie food products, herbal and cosmetics), using the design in accordance with their respective target. The results showed that ucts such as fruit juice, yoghurt, jelly, carbonated beverage (food) and body lotion (cosmetic), and can contribute to the natural color at a time serves as a source of bioactive in effervescent tablets.

Aktivitas Sitotoksik Fraksi Heksana Terung Pokak (Solanum torvum) terhadap Sel Kanker T47D Helilusiatiningsih, Nunuk; Yunianta, Yunianta; Harijono, Harijono; Widjanarko, Simon Bambang; Sujuti, Hidayat
Jurnal Kedokteran Brawijaya Vol 30, No 4 (2019)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2019.030.04.4

Terung pokak adalah tanaman dari genus Solanum yang diperkirakan memiliki sifat antikanker. Tujuan penelitian ini menganalisis kandungan dan aktivitas sitotoksik fraksi heksana terung pokak terhadap sel kanker T47D secara invitro. Uji identifikasi senyawa pada fraksi heksana terung pokak menggunakan uji kualitatif dengan penapisan fitokimia danÂ (Gas Chromatography-Mass Spectometry), uji sitotoksik menggunakan metode MTT, uji siklus sel kanker T47D dan apoptosis menggunakan metode flowcytometry.Â Hasil uji fitokimia menunjukkan terung pokakÂ mengandung alkaloid, saponin, glikosida dan steroid.Â Hasil uji identifikasi kimia fraksi heksanaÂ terung pokak menunjukkan 29 komponen yaitu asam asetat, asam propionat, 2- pentenal, 2- metilfuran, 1- penten-3-on, asam butirat, 2 -metilbutan, 2,3 butanedion, dimetil disuksipirazin, lfida, asam valerat, furfural, 3- heksanon, metional, heksanal, benzaldehid, 2-heptenal, 4- heptenal, 1,5 - octadien 3-on, 2- butilfuran, 3,5- oktadien-2- on, 1 okten-3-on, 2-pentilfuran, 2,6-nonadienal, 2- nonenal, 2- Isopropil-3-metoksipirazin, linalool, 2- isobutil metoksipirazin, dekalakton. Fraksi heksana terung pokak bersifat sitotoksik terhadap sel kanker T47DÂ dengan IC50 sebesarÂ 85,58Âµg/mL. Fraksi heksana terung pokak dapat menghambat siklus sel T47D pada fase G0-G1 sebesar 35,84%, fase S 27,05%, fase G2-M 37,46% dari pengamatan 20.000 sel T47D . Fraksi heksana terung pokak dapat memacu apoptosis awal sebesar 28,89% dan apoptosis akhirÂ 1,04% dari pengamatan 20.000 sel T47D.Â Hasil tersebut menunjukkan bahwaÂ fraksi heksana terung pokak bersifat sitotoksik, menghambat proliferasi dan memacu apoptosis sel T47D, sehingga layak dikembangkanÂ sebagai antikanker.

OPTIMASI DURASI DAN RASIO BAHAN PER PELARUT EKSTRAK DAUN PEPAYA UNTUK UJI AKTIVITAS ANTIBAKTERI Sabathani, Anniversary; Widjanarko, Simon Bambang; Yuwono, Sudarminto Setyo
Jurnal Teknologi Pertanian Vol 19, No 3 (2018)
Publisher : Fakultas Teknologi Pertanian Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jtp.2018.019.03.6

AbstrakTujuan penelitian ini adalah mengetahui kombinasi waktu sonikasi dan bahan per pelarut (b/v) ekstrak daun pepaya segar, yang menghasilkan respon total fenol, aktivitas antioksidan (IC50), dan rendemen yang optimum; juga untuk mengetahui efek dari dosis ekstrak daun pepaya pada aktivitas antibakteri Escherichia coli dan Staphylococcus aureus. Ekstrak daun pepaya dihasilkan menggunakan metode ultrasonik dengan pelarut aquades. Rancangan penelitian menggunakan Response Surface Method, sedangkan desain eksperimen menggunakan General Factor Design, dengan satu faktor yang terdiri dari 6 tingkat dosis ekstrak daun pepaya, kontrol positif dan negatif, diulang 3 kali. Kontrol positif adalah kertas cakram mengandung 10 Î¼g ampisilin untuk bakteri Staphylococcus aureus, kertas-cakram mengandung 30 Î¼g kloramfenikol untuk Escherichia coli, sedangkan kontrol negatif adalah aquades steril. Hasil penelitian menunjukkan kombinasi b/v 16.92 g/100 ml dengan lama waktu ekstraksi daun pepaya 14.36 menit dan menghasilkan tiga respon optimum rendemen 2.89%, total fenol 50.03 mgGAE/g, dan aktivitas antioksidan (IC50) 211.924 ppm. Ekstrak daun pepaya pada konsentrasi 3.125 mg/ml, 6.25 mg/ml, dan 12.5 mg/ml tidak berpengaruh terhadap perkembangan bakteri Staphylococcus aureus dan Escherichia coli, dan berpengaruh mulai 25 mg/ml, 50 mg/ml, 100 mg/ml. Hal ini menunjukkan bahwa ekstrak daun pepaya berpotensi menahan perkembangan bakteri Staphylococcus aureus dan Escherichia coli.Â AbstractThe objective of this research is to know the combination of time duration of sonication and the ratio of the weight of material per solvent of fresh papaya leaf, which produce optimum response of total phenol, antioxidant activity (IC50), and rendemen; and to know the effect of the dose of papaya leaf extract on antibacterial activity, Escherichia coli and Staphylococcus aureus. The papaya leaf extract is resulted by using ultrasonic method with aquades. Experimental design is using response surface method and general factor design, with one factor consisting of 6 levels of papaya leaf extract dose, negative, and positive control and repeated 3 times. The positive control is disc-paper containing 10 Î¼g ampicillin for Staphylococcus aureus bacteria, disc-paper containing 30 Î¼g chloramphenicol for Escherichia coli. Whereas the negative control is sterile aquadest. The results shows a combination of the ratio the weight material per solvent 16.92 g/ 100 ml with the duration of papaya leaf extraction 14.36 minutes and yields three optimum responses: rendemen of 2.89%, total phenol of 50.03 mgGAE/g, and antioxidant activity (IC50) 211.924 ppm, furthermore pepaya leaf extract at concentrations of 3.125 mg/ml, 6.25 mg/ml, and 12.5 mg/ml does not have any effect on the development of Staphylococcus aureus and Escherichia coli bacteria, and only has an effect of 25 mg/ml, 50 mg/ml, 100 mg/ml. This suggests that papaya leaf extract has the potential to withstand the development of Staphylococcus aureus and Escherichia coli bacteria.Â

Potential Use of Compounds from Neem Leaves (Azadirachta indica Juss) as PPARg and ERa Inhibitors to Control Breast Cancer Cell Growth In Silico Model Supriyanto, Supriyanto; Rifa'i, Muhaimin; Yunianta, Yunianta; Widjanarko, Simon Bambang
ALCHEMY Vol 8, No 1 (2020): ALCHEMY: Journal of Chemistry
Publisher : Department of Chemistry, Faculty of Science and Technology UIN Maulana Malik Ibrahim Malan

Treatment using herbs is currently growing rapidly. Compounds in herbal plants can cure various degenerative diseases. The study aims to analyze the potency of nimbin, deacetylnimbin, salanin, and deacetylsalanin compounds in the neem leaves extract to inhibit target proteins namely PPARg and ERa. PPARg is the main regulator of the function of adipose tissue microvascular endothelial cells (aMVECs) while ERa is a protein that mediates all estrogen effects and it is important in the growth of prostate and breast cancer. Inhibition of ERa can prevent the proliferation and growth of breast cancer cells by affecting the performance of estrogen which binds to hormonal receptors and causes inhibition of breast cancer cell proliferation. The results of in silico analysis show that deacetylnimbin can inhibit ERa protein. The docking analysis shows that deacetylnimbin has the potential to replace tamoxifen as a breast cancer drug. The other studies such in vitro and in vivo are needed to validate in silico study.

Immunomodulatory Activity of Methanol Leaf Extract of Neem (Azadirachta indica Juss) Against Suppressor and Proinflammatory Molecules Supriyanto, Supriyanto; Widjanarko, Simon Bambang; Rifa'i, Muhaimin; Yunianta, Yunianta
Journal of Tropical Life Science Vol 11, No 3 (2021)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.11.03.07

Neem plant is rich in bioactive constituents, which make it massively discussed the treatment of various diseases. A study on the immunomodulatory activities of neem is given here. This current work aimed to investigate the effects of neem leaf extract on immunocompetent cells. In vivo experiment was carried out using mice (Mus musculus) Â induced with DMBA, comprising positive control, negative control, and treatments of neem leaf extracts (250, 500, and 1000 ppm). Data obtained from flow cytometric analysis were evaluated using BD Cellquest ProTM software, then statistically analyzed in SPSS version 21. Parametric analysis in one-way ANOVA was performed at a significance level of 5%. The significant difference was compared in the Duncan test. The results showed that administration of neem leaf extracts significantly affected the expression of CD4+, CD8+, CD25+, CD62L, IL-10, and IL-17 cells .Neem leaf extract has immunomodulatory activities by increasing pressure molecules and decreasing pro-inflammatory molecules

Complex Compound with Transitional Metal of Akway Bark (Drimys piperita Hook f.) as Low Molecular Weight Scavenging Antioxidant: a Computational Study Hutasoit, Hostalige; Djoko, Dionysius Joseph; Sumitro, Sutiman B; Widjanarko, Simon Bambang
Journal of Tropical Life Science Vol 11, No 3 (2021)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.11.03.02

Akway (Drimys piperita Hook f.) was known as an endogenous plant of Indonesia. This plant was investigated as free radical scavenger based on paramagnetic properties. This study aimed to identify the bioactive compound and the role of Fe metals ions to enhance the free radical scavenger capacity as Low molecular weight antioxidant (LWMA) of akway. This study was designed by ultra-performance liquid chromatography (UPLC) coupled with ultra-high-resolution time of flight-mass spectrometry detector (TOF-MS), docking (Pyrex and Discovery Studio 2016 Client) and pharmacokinetic properties prediction (SwissADME). UPLC-TOF-MS analysis showed that herbal akway bark has five molecular formula (C4H3N10O21-, C14H19N4O91-, C4H7N6O51-, C15H28NO31+, and C23H32NO71+). The docking was illustrated the complex binding akway formula with Fe and its role as a metal donor and metal acceptor. It also confirmed on pharmacokinetics properties prediction which molecular compounds of akway have aqueous solubility. It meant the herbal akway bark complexed to Fe could be a low molecular weight antioxidant and it could be escalated free radical scavenger capacity.

CHEMICAL CHARACTERISTIC AND ANTIOXIDANT ACTIVITY OF METHANOL EXTRACT NEEM LEAVES (AZADIRACHTA INDICA JUSS) Supriyanto, Supriyanto; Widjanarko, Simon Bambang; Rifa'i, Muhaimin; Yunianta, Yunianta
AGROINTEK Vol 15, No 2 (2021)
Publisher : Agroindustrial Technology, University of Trunojoyo Madura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21107/agrointek.v15i2.10605

The neem plant (Azadirachta indica) is a herb with the potential as a source of antioxidants. This study aimed to identify compounds that exist in the neem leaf and determine their antioxidant activity. Neem leaf extract was collected by using 80% methanol. Â Furthermore, methanol extracts from neem leaves with the highest antioxidant activity were partitioned with n-hexane, ethyl acetate, and water. This research were analyzed by partition for antioxidant activity, and DPPH (1,1-diphenyl-2-pycrilhydrazil) and the half-maximal inhibitory concentration (IC50) values were determined. The results showed that the ethyl acetate partition had the highest antioxidant activity, with IC50 values of 1.004 Âµg/ml. Neem leaf extract has the potential for a use as an herbal medicine in the treatment of various diseases..

Co-Authors A Aulanni'am A. Harijono Aan Muzaky Kusuma Achmad Subagio Adinda Ayu Dyahnugra Adinda Ayu Dyahnugra Agnes Christy Margaretha Agnes Christy Margaretha Ahmad Dhiaul Khuluq Ahmad Zaki Mubarok AJI SUTRISNO Aji Sutrisno Amanda Krysanti Amanda Krysanti Ambrosia Adela Merry Christianita Ambrosia Adela Merry Christianita Amira Hasnanuha Ulayya Andina Rahma Safitri Andina Rahma Safitri, Andina Rahma Anna Nur Hidayati Anna Nur Hidayati, Anna Nur Anni Faridah Arina Manasika Arina Manasika Army Ika Prastini Army Ika Prastini Aulanni'am, Aulanni'am AulanniÃ¢â‚¬â„¢am . Aulanni’am Aulanni’am Bambang Dwi Argo Bambang Susilo BAMBANG SUSILO Chilyatul Mustafidah Chilyatul Mustafidah Christovorus Gusung Saputra Deara Gita K Dego Yusa Ali Delima, Meita Putri Devy Ulandari Dewi Liesnoor Setyowati Dian Widya Ningtyas Djoko, Dionysius Joseph Dr.Ir. Yunianta, DEA Dyah Ayu Anggraeni Dyah Ayu Anggraeni Dyah Tri Wahyuni Dyah Tri Wahyuni Eka Dessy Natalia Eka Dessy Natalia Elfi Anis Saati Elfira Rosyadi Elfira Rosyadi Elliza Rachma Dwiyanti Elliza Rachma Dwiyanti Elok Zubaidah Endrika Widyastuti Engganeyski Jana Claudia Engganeyski Jana Claudia, Engganeyski Jana Erni Sofia Murtini Etis Finallika Etis Finallika Eva Nur W Fath Isandy Rozaq Feronika Heppy Sriherfyna Grace Maria Ulfa H., Nunuk Hanif, Muhamad Ibnu Harni Ayu Sari Harni Ayu Sari Hidayat Sujuti Hutasoit, Hostalige Ikke Ayu Sulistyaningrum Indria Purwantiningrum Indria Purwantiningrum Indria Purwantiningrum Irma Nopriyani Ivy Dian Puspitasari Prabowo Jatmiko Eko Witoyo Jaya Mahar Maligan Johana Megawati Julio Kurniawan Julio Kurniawan Karina Kristanti Ekarani Rahardjo Karina Kristanti Ekarani Rahardjo Karina Pradipta Ananda Karina Pradipta Ananda, Karina Pradipta KIKI FIBRIANTO Kurnia Wulandari Latifa Putri Aulia Marlita Eklesia Masruri Masruri Masruri Meilani Anugrah Gusti Meilani Anugrah Gusti, Meilani Anugrah Mimin Suryani Mochamad Affandi Montanus Barep Hiovenaguna Muhammad Irsan K Muhammad Kharis Abdullah Affandy Nela Agustin Kusuma Wardani Nelsy Dian Permatasari Ni'maturohmah, Eva Nilta Shabrina Itsnani Nimas Ratu Kali Dewi Nimas Ratu Kali Dewi Novan Nandiwilastio Novan Nandiwilastio Nur Ida Panca Nugrahini Okky Meidiana Prameswari Okky Meidiana Prameswari Pamungkas, Bangkit Puji Putra Patrick Pantang W Rahmah Utami Budiandari Rifa'i, Muhaimin Rista Fitria Anggraini Rizka Aulia Rahma Rizki Tika Mawarni Rizki Tika Mawarni Rofiq Sunaryanto Sabathani, Anniversary Saiin Mustafa Saiin Mustafa Saleh, Nuriyya Sandymas Satria Irawan Sandymas Satria Irawan SARASWATI, Ayu Rahayu Setyo Pambudi Setyo Pambudi Siti Aisyah Nurfiliyah Siti Aisyah Nurfiliyah Siti Narsito Wulan Sudarminto Setyo Yuwono Supriyanto Supriyanto Susilo, Donor Utomo M. Susinggih Wijana Sutiman B. Sumitro Taufik Boby Wisesa Taufik Boby Wisesa Thabah Sigit Suwasito Theovilla RRD THEOVILLA RRD, THEOVILLA Tri Wahono Tunjung Mahatmanto Veronica Lydia Violetta Prisca Effendi Violetta Prisca Effendi Vivien Fathuroya Widodo Widodo Widya Dwi Rukmi Putri Willy Yanuar Wiwit Mariana Yuli Witono Yumna Khoirunnisa Zamnia Wahyuli

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