Article Per Year (5 Year)
p-Index From 2021 - 2026
3.799
P-Index
This Author published in this journals
All Journal Jurnal Kesehatan Andalas Molecular and Cellular Biomedical Sciences (MCBS) Syntax Literate: Jurnal Ilmiah Indonesia Indonesian Journal of Obstetrics & Gynecology Science Journal of Midwifery JIK- JURNAL ILMU KESEHATAN Health and Medical Journal Andalas obstetrics and gynecology journal Jurnal Health Sains Jurnal Ilmu Kesehatan Indonesia (JIKSI) Jurnal Riset Ilmiah
Antonius, Puja Agung
Andalas University
Humanities Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

Published : 26 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 26 Documents
Search

 1   2   3 
Adjuvant Chemotherapy For FIGO Stage IIA2 Cervical Cancer : A Case Report Deni Heryanto; Syamel Muhammad; Puja Agung Antonius
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 2 (2024)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.2.792-800.2024

Abstract

Background : Cervical cancer ranked as the third most prevalent cancer among women. This case report is to examine the current status of adjuvant chemotherapy in the treatment of early-stage cervical cancer as documented in the literature. Currently, there is no established evidence supporting the therapeutic efficacy of adjuvant chemotherapy as a standalone treatment following radical hysterectomy surgery. Nevertheless, some literature recommend the use of adjuvant radiotherapy (AR), adjuvant chemotherapy (AC), or concomitant chemoradiotherapy (CCRT) as the standard adjuvant therapies for early-stage cervical cancer following radical hysterectomy with positive prognostic factor. Case report: A 53-year-old female was diagnosed with stage IIA2 in April 2021. The histology type was determined to be keratinized squamous cell carcinoma, moderately well differentiated. The patient underwent a radical hysterectomy, resulting in the acquisition of uterine and cervical tissue measuring 11x11×6 cm. The histology results revealed moderately to poorly differentiated keratinizing squamous cell carcinoma, with no invasion of the parametrium or pelvic lymph nodes with vaginal cutting margin is free of tumor growth, but lymph vascular space invasion was present. Subsequently, adjuvant chemotherapy was administered using carboplatin (AUC 5) and paclitaxel for a total of 6 cycles. After 2 years with follow-up with CT-Scan examination in April 2023 confirmed the absence of any residual mass. Conclusion: A radical hysterectomy combined with adjuvant chemotherapy has been shown to reduce the chance of recurrence or progressiveness of the disease, in which this patient did not experience a recurrence after two years of treatment  
Rapidly Growing Ovarian Granulosa Cell Tumor Following Complete Debulking for Suspected Ovarian Cancer with Histopathology Result of Benign Ovarian Cyst Muhammad, Syamel; Antonius, Puja Agung; Oktavian, Rizki; Savannah, Aisha
Molecular and Cellular Biomedical Sciences Vol 7, No 3 (2023)
Publisher : Cell and BioPharmaceutical Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21705/mcbs.v7i3.352

Abstract

Ovarian granulosa cell tumor (GCT) is a rare low-grade malignancy condition. One type of GCT is adult GCT (AGCT), which has the tendency for late recurrence. AGCT is clinically palpable and focally cystic and solid. In this case report, a condition of recurrent ovarian cancer after laparotomy debulking surgery was reported. A 57-year-old woman, who was diagnosed with AGCT, had a history of laparotomy debulking three months prior and complained of abdominal pain and enlargement, along with significant weight loss. Ultrasound examination revealed a solid cyst, raising suspicion of recurrent ovarian cancer. Laboratory results indicated elevated CA-125 levels. Histopathology results confirmed metastasis of AGCT, after the second laparotomy debulking was done. Recurrence of GCT is uncommon within three months of debulking. In this rare condition, we suggested a laparotomy debulking and adjuvant chemotherapy as a treatment. Effectiveness of treatment of recurrent disease is an independent risk factor to reduce the risk of another relapse and increase the survival rate.Keywords: granulosa cell tumor, ovarian cancer, debulking
Perbandingan Lama Rawatan Pasien Sectio Caesarea Metode ERACS dengan Metode Konvensional di RSIA Restu Ibu Padang Harbaindo, Shavira Quincy; Effendi, Rinal; Linosefa, Linosefa; Suharti, Netti; Rustini, Rini; Antonius, Puja Agung
Jurnal Ilmu Kesehatan Indonesia Vol. 5 No. 4 (2024): Desember 2024
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v5i4.989

Abstract

Latar Belakang. Angka sectio caesarea yang mengalami peningkatan dari tahun ke tahun mendorong banyaknya potensi yang timbul untuk mengembangkan pelayanan, salah satunya dari aspek kecepatan pemulihan yang ditawarkan metode ERACS (Enhanced Recovery After Caesarean Surgery). Metode ERACS memiliki beberapa perbedaan dari metode konvensional, dan menurut penelitian terdahulu, metode ERACS menunjukan lebih banyak keunggulan yang dapat menguntungkan pasien, salah satunya dari segi lama rawatan. Objektif. Mengetahui perbandingan lama rawatan pasien sectio caesarea metode ERACS dengan metode konvensional di RSIA Restu Ibu Padang. Metode. Jenis penelitian ini adalah analitik observasional dengan desain kohort. Data diambil secara retrospektif dari rekam medik pasien sectio caesarea di RSIA Restu Ibu periode November-Desember 2021. Sampel berjumlah 67 pasien yang dipilih menggunakan total samplingberdasarkan kriteria inklusi dan eksklusi. Hasil. Frekuensi lama rawatan paling tinggi pada pasien sectio caesarea dengan metode konvensional adalah lebih dari atau sama dengan 3 hari, sedangkan lama rawatan pada metode ERACS menunjukan paling banyak pasien dirawat selama 2 hari. Hasil analisis dengan uji Chi-square pada perbandingan lama rawatan antara metode ERACS dengan metode konvensional di rumah sakit tempat penelitian menunjukan nilai p=0,002. Kesimpulan. Kesimpulan dari penelitian ini adalah terdapat hubungan yang signifikan (p<0,05) dari perbandingan lama rawatan antara metode ERACS dengan metode konvensional di RSIA Restu Ibu Padang.
High Grade Appendiceal Mucinous Neoplasma Reviewing Primary Tube Malignancy : A Case Report Kurnia, Irfan; Antonius, Puja Agung; Muhammad, Syammel
Andalas Obstetrics And Gynecology Journal Vol. 7 No. 2 (2023)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.7.2.467-472.2023

Abstract

Appendiceal mucinous neoplasms (AMNs) are rare tumors accounting for less than 1% of all cancers. The clinical presentations of AMN vary significantly and the diagnosis of most patients is during surgery for suspected appendicitis, peritonitis or gynecological cancer. There were many case reports AMN mimicking an ovarian cancer. In this case, we reported a 64-year postmenopause woman with diagnosed peritonum carcinomatosis dd/ ovarian cancer and it actually AMN in RSUP dr. M. Djamil Padang, West Sumatera. The diagnosis is estimated by ultrasonography (USG), computed tomography (CT), magnetic resonance imaging (MRI) and diagnostic laparoscopy followed by histopathologic verification. The evaluation of the prognosis of appendix mucinous adenocarcinoma mainly depends on whether the tumour is in an advanced stage, the degree of malignancy, and whether an AMN is formed
PERBANDINGAN FAKTOR RISIKO DAN MANIFESTASI KLINIS HPV 16 DENGAN HPV 18 PADA PENDERITA KARSINOMA SERVIKS Anavelda, Aura Putri; Putra, Andani Eka; Defrin, Defrin; Suharti, Netti; Antonius, Puja Agung; Elmatris, Elmatris
SINERGI : Jurnal Riset Ilmiah Vol. 2 No. 4 (2025): SINERGI : Jurnal Riset Ilmiah, April 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/sinergi.v2i4.1114

Abstract

Background: High-risk Human Papillomavirus (hrHPV) infection causes 99.7% of cervical carcinoma cases. Among the thirteen types of hrHPV, types 16 and 18 have a strong correlation with- cervical carcinoma. HPV 16 infection makes the immune system in the cervix hyporesponsive compared to HPV 18 infection. Objective: This study aims to compare the risk factors and clinical manifestations of HPV 16 with HPV 18 in cervical carcinoma patients. Method: This is an analytic study with a retrospective cohort approach using secondary data from the research of Dr. dr. Andani Eka Putra, M.Sc and dr. Syandrez Prima Putra which has been collected into a research master table. The sampling technique was non-probability sampling with convenience sampling on 38 respondents whose specimens were stored at the Central Laboratory of Diagnostics and Research on Infectious Diseases, Faculty of Medicine, Andalas University. Data analysis was carried out using Fisher's Exact test. Results: The results of statistical tests on the comparison of marriageable age between patients with HPV 16 and HPV 18 types showed a value of p = 0.038 (p <0.05). In this study, women who are > 45 years old, married early (<20 years), have a low level of education, work as housewives, and have a multiparity history are at high risk of cervical carcinoma. Patients with HPV 16 and 18 had risk factors and clinical manifestations were not much different (p>0.05). Conclusion: There is no significant comparison of the risk factors and clinical manifestations of HPV 16 with HPV 18 in patients with cervical carcinoma.
Correlation of Leukopenia with Vitamin D Levels in Ovarian Cancer Patients Undergoing Platinum-Taxane-Based Chemotherapy Antonius, Puja Agung; Firdawati, Firdawati; Syamel Muhammad; Yusrawati, Yusrawati; Karmia, Hudila Rifa; Wijaya, Caesar Muhammad
Andalas Obstetrics And Gynecology Journal Vol. 9 No. 2 (2025)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.9.2.251-258.2025

Abstract

Introduction: Ovarian cancer is a significant cause of death in women. One of the management of advanced ovarian cancer patients is chemotherapy. The effects of administering Platinum-Taxane-Based chemotherapy to ovarian cancer patients show side effects of myelosuppression, one of which is leukopenia. Methods: This type of study is a correlation analytical study with a cross-sectional design from October 2023 to May 2024 at Dr. M. Djamil Central General Hospital Padang. The patients included were ovarian cancer patients who underwent Platinum-Taxane-Based chemotherapy with laboratory results of leukopenia. Results: From 70 patients, it was found that 37 patients (52.9%) had grade I leukopenia, 27 patients (38.6%) had grade II, and 6 patients (8.6%) had grade III. Based on the results obtained, in grade I leukopenia, the average vitamin D value is 13.162 ng/mL, grade II has an average vitamin D value of 11.851 ng/mL, grade III has an average vitamin D value of 14.333 ng/mL. The study results showed a relationship between leukopenia and vitamin D levels p = 0.034 (p < 0.05). Conclusion: There was a relationship between leukopenia and vitamin D levels in ovarian cancer patients undergoing Platinum-Taxane-Based Chemotherapy at Dr. M. Djamil Central General Hospital Padang.
Uterine Corpus Endometrial Carcinoma in Young Women Caesar Muhammad Wijaya; Antonius, Puja Agung; Syamel Muhammad; Anugrah, Mutia Paramadita
Andalas Obstetrics And Gynecology Journal Vol. 9 No. 1 (2025)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.9.1.161-166.2025

Abstract

Introduction : Endometrial carcinoma is a malignant epithelial tumor that forms in the uterus's inner lining, or endometrium. The average age at diagnosis is 61 years, with cases diagnosed after 50 years more than 90%. Endometrial carcinoma is rare in young women, usually defined as occurring under age 50 or menopause, with rare cases occurring under age 40. Case Report : A 35-year-old woman nulliparous complaints of abdominal pain since 3 months ago and complained of weight loss. Based on the anamnesis, the patient is not married. On physical examination, revealed an area of firmness in the suprapubic region associated with pain on palpation. On ultrasound examination, the uterus was found to be anteflexed, with an inhomogeneous appearance, and a solid cystic mass along the uterus. Adnexa measuring 10.02 x 10.20 x 12.02 cm, vascular scale 4, not clearly defined. The patient was diagnosed with suspected uterine corpus carcinoma. Result : In this patient, a total hysterectomy and bilateral salpingo-oophorectomy were performed because the patient did not want fertility. Conclussion : In young women who want to preserve fertility, conservative management is often implemented. But, when fertility-sparing treatment is not considered, the rate of recurrence and progression is considerably low in this case. Ultimately, although fertility-sparing treatments are an attractive alternative to surgery resulting in permanent loss of fertility, unfortunately, they can only be applied in a subset of cases. The standard surgical procedure recommended is a total extra-fascial hysterectomy with bilateral salpingo-oophorectomy. Keywords: Uterine Corpus Endometrial Carcinoma, Young Women
PREVALENSI ANEMIA PADA KEHAMILAN : SEBUAH TINJAUAN LITERATUR SISTEMATIS Azmira, Nazurah; Defrin, Defrin; Burhan, Ida Rahmah; Rustam, Erlina; Antonius, Puja Agung; Yusri, Elfira
SINERGI : Jurnal Riset Ilmiah Vol. 2 No. 9 (2025): SINERGI : Jurnal Riset Ilmiah, September 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/sinergi.v2i9.1374

Abstract

Background : Anemia has become a public health problem that bring many potencial danger to both maternal and neonatal side. Many studies show that there are significant correlation between maternal mortality and anemia during pregnancy.Objective: This review is done to determine the prevalence and risk factors of anemia among pregnant women Methods : This study is a systematic literature review focused on the prevalence of anemia during pregnancy from 2011-2020. Literature search on Pubmed and Proquest databases was carried out to identify studies included in inclusion criteria related to prevalence of anemia during pregnancy. In this review, 60 articles were reviewed after 4105 articles found in both databases were screened using PRISMA guidelines. A total of 49589 participants from 20 developing countries were included. Results : The results showed that the rate of anemia in pregnancy range from 7,4% to 90%, with an average of 36,2%. The most reported risk factors are low economic level/ household income (10,2%), maternal age (9,6), rural residence (7,8%), educational status of the mother (7,2%)and less consumption of iron/folic acid (7,2%). Conclusion : Based on the review, available evidence suggest that prevalence of anemia remain high especially in low and middle income countries. Maximum efforts need to be initiated to help prevent anemia during pregnancies. Public should be educated on early initiation of antenatal care to enhance surveillance, identification and treatment of anemia
Perineal Trauma Impact on Postpartum Sexual Function: A Cross-Sectional Study Using Female Sexual Function Index Karsa, Salsa Bila; Antonius, Puja Agung; Fitria, Henni; Insani, Aldina Ayunda; Fadila, Zurraya; Dimba, Modester
JIK-JURNAL ILMU KESEHATAN Vol 9, No 2 (2025): JIK-OKTOBER VOLUME 9 NOMOR 2 TAHUN 2025
Publisher : UNIVERSITAS ALIFAH PADANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33757/jik.v9i2.1459

Abstract

Background: Perineal trauma resulting from vaginal delivery can negatively impact postpartum sexual function; however, data from Southeast Asian populations are still scarce.Objective: We aimed to study the relationship between perineal trauma and sexual dysfunction measured by the Female Sexual Function Index (FSFI) among postpartum women in Indonesia.Methods: A cross-sectional study was carried out at Pauh Community Health Center, Padang City, between May and June 2025. We used purposive sampling to recruit forty-six women who had a vaginal delivery within the last six months. Sexual function was measured using the Indonesian FSFI version, a tool validated for the Indonesian population, with scores below 26.55 indicating dysfunction. Perineal trauma condition was ascertained from the medical record. The chi-square test assessed the association between perineal trauma and sexual dysfunction.Results: Sexual dysfunction prevalence was 54.3% (n=25). Of the women who had perineal trauma, 82.6% were sexually dysfunctional, compared to 26.1% in the group without trauma. The relationship was statistically significant (p=0.001) with a crude odds ratio of 13.81 (95% CI: 3.46-55.12). The pain and desire domains were affected the most.Conclusion: Perineal trauma is a significant risk factor for postpartum sexual dysfunction among Indonesian women. Besides that, health care workers should promote the sexual health of their clients by regularly integrating the screening of sexual health into routine postpartum care, applying evidence-based interventions to reduce perineal injury, and providing easy access to pelvic floor rehabilitation services as a way to improve maternal quality of life.
Carcinoma Endometrioid Ovary pada Struma Ovarii Muhammad, Syamel; Antonius, Puja Agung; Meuthia, Susan; Savannah, Aisha
Health and Medical Journal Vol 5, No 3 (2023): HEME September 2023
Publisher : Universitas Baiturrahmah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33854/heme.v5i3.1361

Abstract

Kanker ovarium merupakan penyebab utama kematian pada wanita yang didiagnosis sebagai kanker ginekologi. Tingginya angka kematian akibat kanker ovarium karena mayoritas kasus bersifat asimptomatik dan skrining yang dilakukan untuk menegakkan diagnosis masih kurang. Hal ini menyebabkan kanker ovarium dikenal sebagai silent killer. Etiologi spesifik kanker ovarium hingga belum diketahui dengan pasti, namun teradapat beberapa faktor risiko yang berperan terhadap terjadinya kanker ovarium. Faktor risiko genetik diduga berkaitan erat dengan kejadian kanker ovarium, diantaranya mutasi pada gen TP53, BRCA1 dan BRCA2.  Diagnosis kanker ovarium sulit dilakukan pada stadium dini karena tidak adanya gejala spesifik.  Untuk menegakkan diagnosis kanker ovarium dibutuhkan anamnesis, pemeriksaan fisik dan pemeriksaan penunjang seperti CT scan, USG, pemeriksaan tumor marker dan biopsi. Hingga saat ini, pembedahan masih menjadi penatalaksanaan utama bagi kanker ovarium. Pemeriksaan histopatologi juga perlu dilakukan untuk menentukan keganasan, jenis kanker, dan penentuan staging. Kemoterapi adjuvan diberikan pada pasien setelah pembedahan, kecuali jika penyakit hanya terbatas pada ovarium dan  pada kanker yang tidak bisa dioperasi. Prognosis kanker ovarium bergantung dari jenis kanker, stadium  dan komplikasi yang terjadi. Pada jurnal ini dilaporkan kasus seorang pasien perempuan, berusia 59 tahun dengan carcinoma endometrioid ovary pada struma ovarii.
Co-Authors Anavelda, Aura Putri Andani Eka Putra Annissa Qatrunnada Anugrah, Mutia Paramadita Azmira, Nazurah Caesar Muhammad Wijaya Defrin, Defrin Deni Heryanto Dia Rofinda, Zelly Dia Dimba, Modester Effendy Fila Elmatris Sy Erlina Rustam Fadila, Zurraya Fajriman Fajriman Fajriman, Fajriman Fardani Putra Syafar Firdawati Firdawati Firdawati, Firdawati Fitrayeni Fitrayeni Fitria, Henni Harbaindo, Shavira Quincy Hariyono Winarto Ida Rahmah Burhan Insani, Aldina Ayunda Irfan Kurnia Karmia, Hudila Rifa Karsa, Salsa Bila Kurnia, Irfan Linosefa Linosefa Lusi Jelita Sari Meuthia, Susan Mohamad Reza Muhammad Zaldy Rasyid Putra Muhammad, SpOG(K)-Onkogin, Dr. dr. Syamel Muhammad, Syammel Netti Suharti, Netti Putri, Biomechy Oktomalio Rahman, Chairani Rasyid Putra, Muhammad Zaldy Rinal Effendi Rini Rustini Saberko, Santy Salsabila Dhiyaa Syifa Santy Saberko Sari, Lusi Jelita Savannah, Aisha Sugeng Santoso Syafar, Fardani Putra Syamel Muhammad Syammel Muhammad Syammel Muhammad Tricia Dewi Anggraeni Virgusrudhina, Mitra Wenny Nursa Octarina Wijaya, Caesar Muhammad Yusrawati Yusrawati Yusri, Elfira