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All Journal MEDIA MEDIKA INDONESIANA Journal of Nutrition and Health Rotasi JURNAL GIZI INDONESIA Jurnal Psikologi JURNAL TEKNIK MESIN Jurnal Kedokteran Diponegoro Medical Journal of Indonesia Journal of Biomedicine and Translational Research Global Medical and Health Communication The Indonesian Biomedical Journal Sari Pediatri Paediatrica Indonesiana Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Indonesian Journal of Global Health research Diponegoro International Medical Journal (DIMJ) Mechanical Engineering for Society and Industry
Tri Indah Winarni
Center For Biomedical Research (CEBIOR), Faculty Of Medicine, Universitas Diponegoro, Jl. Prof. Sudharto, SH, Tembalang, Semarang
Aerospace Engineering Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Control & Systems Engineering Dentistry Education Electrical & Electronics Engineering Energy Engineering Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Transportation

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Journal : JURNAL GIZI INDONESIA

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Anthropometric Markers, Visceral Adipocyte Index, Inflammation Markers and Bone Density in Reproductive Obese Women Meita Hendrianingtyas; Lisyani B.Suromo; Tri Indah Winarni
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 10, No 2 (2022): Juni
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jgi.10.2.135-140

Abstract

Background: Obesity has been associated with the risk of various diseases. The correlation between anthropometry and bone health is complex. Visceral adipocyte index (VAI) is one of the compositions of body fat compositions that mostly associated with proinflammatory cytokine, which can stimulate C- reactive protein (CRP) that affects bone density.Objectives: This study aimed to prove the correlation between VAI, CRP and BMD in Asian reproductive obese womenMaterials and Methods: A cross sectional study was conducted in November 2020 - February 2021 and a total of 134 women of reproductive age with obesity participated in this study. Weight, height, body mass index (BMI) and rate of visceral fat were measured by body composition analyzer. Waist (WC) and hip circumferences (HC) measured by using tape; lipid profile and CRP level were examined using a clinical chemistry automatic analyzer, and the examination of bone mineral density (BMD) using dual-energy x-ray absorptiometry. Waist to hip ratio (WHR)and VAI calculated manually. Pearson and Spearman test were used for statistical analysis.Results: There were positive weak correlations between weight, height, BMI, WC, HC, rate of visceral fat, WHR and VAI. There were weak positive correlations between HC, WHR and CRP. There were positive moderate correlations between weight, height, BMI, waist, visceral fat, WHR and CRP. Conclusion: Although there were correlations between anthropometric parameters and VAI and also CRP, but we did not found correlation between VAI and CRP to all BMD parameters.
Effect of vitamin D3 supplementation on serum 25 (OH)D Levels, hand grip strength, blood sugar levels, and cognitive function in the elderly Probosari, Enny; Subagio, Hertanto Wahyu; Winarni, Tri Indah; Nugroho, Heri; Manikam, Nurul Ratna Mutu
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 13, No 1 (2024): December
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jgi.13.1.79-87

Abstract

ABSTRACTBackground: The aging process in the elderly can be caused by a decrease in vitamin D precursors and reduced Vitamin D levels due to impaired absorption of Vitamin D. Vitamin D plays a role in cognitive function, acts as an immunomodulator affecting blood glucose levels, promotes muscle atrophy, and affects the intranuclear VDR concentration and gene expression of VDR.Objectives: To determine the effect of vitamin D3 supplementation on Serum 25(OH)D levels, hand grip strength, blood sugar levels, and cognitive function in the elderly.Materials and Methods: This study used a quasi-experimental pre-posttest control group design with a total of 60 subjects included and divided into two groups. The treatment group received vitamin D3 at a dosage of 1000 IU/day for three months, while the control group was given a placebo. Blood serum levels were used to obtained serum 25(OH)D and blood sugar level. Hand grip strength values were measured by a hand grip dynamometer, and cognitive function was assessed using the Mini-Mental State Examination (MMSE) Questionnaire. The data was analyzed using the Wilcoxon test, and the bivariate analysis was performed using the Mann-Whitney test.Results: Most subjects were between 60 and 92 years old and had a vitamin D deficiency. Significant (P<0,05) differences were observed in serum 25(OH)D levels, blood sugar levels, and cognitive function following the intervention. The differences in serum 25(OH)D levels were 8,50±6,17, blood sugar levels were -21,68±25,88, and cognitive function was 2,23±3,05. Additionally, hand grip strength increased after the intervention (mean=0,42±4,66) but was not statistically significant (P=0,633).Conclusion: There is an improvement in cognitive function and a decrease in blood glucose levels, along with an increase in 25(OH)D levels after three months of vitamin D supplementation. However, hand grip strength did not significantly increase after supplementation.Keywords: Vitamin D3 Supplementation; serum 25(OH)D; hand grip strength; blood sugar level; cognitive function; elderly.
Co-Authors A, Mahayu Dewi Achmad Zulfa Juniarto Afif, Ilham Afif, Ilham Yustar Agustini Utari Aisha Balkhar Ali Alifiati Fitrikasari Ammarullah, Muhammad Andria Pragholapati Ani Melani Maskoen Annastasia Ediati Atanasius Priharyoto Bayuseno Azalia, Putri Banundari Rachmawati Bremmy Laksono Budi Mulyono Cinta Cynthia Rudianto Donna Hermawati Edi Dharmana Enny Probosari Farmaditya EP Mundhofir Farmaditya EP Mundhofir Fatinah Shahab Ferdy Kurniawan Cayami Fitria Handayani Gara Samara Brajadenta Gatot Irawan Sarosa, Gatot Irawan Gunawan, I Putu Gde Fredy Hary Tjahjanto Heri Nugroho Hertanto Wahyu Subagio Husaini, Farhan Husaini, Farhan Ali Ignatius Riwanto, Ignatius Indriyati, Rita Inu Mulyantoro J. Jamari Jamari, J Jessica Juan Pramudita Lamura, M Danny Lamura, M. Danny Pratama Lestari, Esa Loyallita Lisyani B.Suromo Lisyani Budipardigdo Suromo Maria Belladonna Rahmawati Maula, Mohammad Meira Erawati Meita Hendrianingtyas Mohamad Izzur Maula Mohammad Sulchan Muhamad Bilal Mursyd, Ariq Imam Nani Maharani Nur Setiawati Dewi Nurul Ratna Mutu Manikam Nydia Rena Benita Sihombing Nyoman Suci Widyastiti Permatasari, Galuh Arum Ponco Birowo Pramudtya, Reza Rafli, Muhammad Rahman Jamal Rama, Leonardo Jalusius Rita Indriyati Selanno, Fradelino Esau Selvia Eva Sabatini Sihombing, Nydia Rena Benita Suardani, Ni Wayan Sue-Mian Then Suhartono, Suhartono Sultana MH Faradz Syarief Taufik Tithasiri Audi Audi Rahardjo Tri Nur Kristina Vynda Ulvyana Wicaksono, Hasyid Ahmad Zulfikar Ali, Zulfikar