Article Per Year (5 Year)
p-Index From 2021 - 2026
1.829
P-Index
This Author published in this journals
All Journal The Indonesian Biomedical Journal Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Jurnal Ilmiah Kesehatan Jurnal Ilmiah Kebidanan Indonesia (Indonesian Midwifery Scientific Journal) Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Medika Teknika : Jurnal Teknik Elektromedik Indonesia Cermin Dunia Kedokteran Jurnal Ilmu Kesehatan Indonesia (JIKSI) Makara Journal of Health Research
Hariyono Winarto
Faculty Of Medicine Universitas Indonesia/ Dr. Cipto Mangunkusumo General Hospital Jakarta
Biochemistry, Genetics & Molecular Biology Education Electrical & Electronics Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Published : 29 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 29 Documents
Search

 1   2   3 
Socio-demographic Profiles of Cervical Cancer Patients at Cipto Mangunkusumo Hospital - 2009-2019 and Its Association with Cancer Stages at Diagnosis Fitriyadi Kusuma; Kemal Akbar Suryoadji; Michael Adrian; Tofan Widya Utami; Hariyono Winarto; Tricia Dewi Anggraeni; Kartiwa Hadi Nuryanto; Muhammad Haekal
Cermin Dunia Kedokteran Vol 49, No 5 (2022): Jantung dan Saraf
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v49i5.1846

Abstract

Objective: To determine the socio-demographic profile of cervical cancer patients at Cipto Mangunkusumo Hospital in 2009-2019 based on educational level, parity, age, residence, and employment status and their relationship to cervical cancer stage at diagnosis. Methods: Comparative analytical study was conducted retrospectively based on medical records in Cipto Mangunkusumo Hospital. The selection was based on data completeness: cervical cancer stages, sociodemographic profiles consisting of education level, parity, age, Java or non-Java Island resident, and occupation. Multivariate analysis calculated the association between socio-demographic factors and cervical cancer stages. Data were analyzed using SPSS v.22.0 and Microsoft Excel. Results: This study included 4,584 patients with complete data. Only 19.3% patients were in the early stage, 63.3% had less than three parities, 82.8% of patients had formal primary school education or less, 80.9% patients were aged 18-65 years, 88.3% patients resided in Java Island, and 80.5% didn’t have the occupation. There was a significant association (p <0.05) between cervical cancer stage and educational level (aOR= 0.86; 95% CI= 0.78-0.94) and age (aOR= 1.46; 95% CI= 1.18-1.40). There is no significant association (p >0.05) between cervical cancer stage and parity, residence, and employment status. Conclusion: Low education and old age (> 65-year-old) were associated with the advanced stage of cervical cancer at diagnosis. Tujuan: Mengetahui profil sosiodemografi pasien kanker serviks di Rumah Sakit Cipto Mangunkusumo tahun 2009-2019 berdasarkan tingkat pendidikan, jumlah paritas, usia, status kependudukan, pekerjaan, serta hubungannya terhadap stadium kanker serviks saat diagnosis. Metode: Penelitian analitik komparatif retrospektif berdasarkan data rekam medis Rumah Sakit Cipto Mangunkusumo. Pemilihan sesuai kelengkapan data: stadium kanker serviks, profil status sosiodemografi yang terdiri atas tingkat pendidikan, paritas, usia, penduduk pulau Jawa atau non-Jawa, dan status pekerjaan. Hubungan antar variabel dianalisis multivariat untukmencari hubungan berbagai faktor sosiodemografi terhadap stadium kanker serviks. Analisis data menggunakan program SPSS versi 22.0 dan Microsoft Excel.Hasil: Terdapat 4.584 pasien kanker serviks yang memenuhi kriteria inklusi. Sebanyak 19,3% pasien dengan stadium awal. Selanjutnya 82,8% pasien memiliki pendidikan formal sekolah dasar atau kurang, 63,3% pasien memiliki jumlah paritas kurang dari tiga, 80,9% pasien berusia antara 18-65 tahun, 88,3% pasien berdomisili di pulau Jawa, dan 80,5% tidak bekerja. Didapatkan asosiasi bermakna (p<0,05) antara stadium kanker serviks dan tingkat pendidikan (aOR = 0,86; 95% CI= 0,78-0,94) dan usia (aOR= 1,46; 95% CI= 1,18-1,40). Tidak ditemukan asosiasi bermakna (p>0,05) antara stadium kanker serviks dengan paritas, domisilikependudukan, dan status pekerjaan. Simpulan: Tingkat pendidikan rendah dan usia lanjut (>65 tahun) berasosiasi dengan stadium lanjut kanker serviks saat diagnosis. 
Thrombositosis sebagai Prediktor Kanker pada Keganasan Ginekologi: a Narrative Review Kusuma, Fitriyadi; Suryoadji, Kemal Akbar; Abdullah, Muhammad Raoul Taufiq; Putra, Abdul Hafiidh Surya; Purwoto, Gatot; Winarto, Hariyono; Utami, Tofan Widya
Jurnal Ilmiah Kebidanan Indonesia Vol 13 No 02 (2023): Jurnal Ilmiah Kebidanan Indonesia (Indonesian Midwifery Scientific Journal) Uni
Publisher : Q PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33221/jiki.v13i02.2616

Abstract

Thrombositosis, peningkatan jumlah trombosit dalam darah, telah dikaitkan dengan kanker pada keganasan ginekologi. Trombositosis dapat dipicu oleh pelepasan sitokin oleh tumor ganas, seperti IL-6. Trombositosis berperan dalam perkembangan kanker melalui perlindungan terhadap sel tumor, produksi faktor pertumbuhan, dan angiogenesis. Tinjauan literatur ini mengumpulkan dan menganalisis penelitian terkait trombositosis sebagai prediktor kanker pada keganasan ginekologi. Pemahaman yang komprehensif tentang hubungan ini dapat membantu pengembangan metode deteksi dini dan terapi yang lebih efektif untuk kanker pada keganasan ginekologi.
The SDGs Perspective of TeleDoVIA Reliability for Cervical Cancer Elimination in 2030: A Cross Sectional Study in Indonesia Widya Utami, Tofan; Nuranna, Laila; Purwoto, Gatot; Winarto, Hariyono; Fitriyadi Kusuma; Rizky Humairah , Inas; Faisha Rahma, Melly; Kekalih, Aria; Peters, Alexander AW
Indonesian Journal of Obstetrics and Gynecology Volume 12 No. 4 October 2024
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v12i4.1956

Abstract

Objective: To describe the prevalence of HPV infection in women with negative Visual Inspection with Acetic Acid (VIA) and introduce Teleconsultation of Documented VIA (TeleDoVIA) as an objective test and provide a rationalization for recommending TeleDoVIA as a “high-performance” test for cervical cancer screening in lower resource settings, from SDGs perspective, to accelerate the achievement of second pillar elimination and the third SDGs target in 2030. Methods: This is a 7-year cross-sectional study. Subjects were recruited consecutively from several public and private health providers in Jakarta. VIA test was documented and consulted to the experts panel (TeleDoVIA). Negative VIA women underwent HPV-DNA testing using SPF10-DEIA-LiPA25 for PCR and electrophoresis. Results: A total of 1,397 negative VIA subjects were collected, consist of 52 HPV-DNA positive. False-negative of VIA was 3.7% (95% CI 0.027–0.047). Conclusion: VIA is a reliable screening method with a low false-negative rate. TeleDoVIA could be recommended as a reliable cervical cancer screening method in low resource settings such as Indonesia, which is in line with the third SDG: good health and well-being. Keywords: Southeast Asia < Asia; public health.
Correlation Between Chemotherapy-Induced Nausea and Vomiting with Quality of Life in Patients with Ovarian Cancer at Dr. Cipto Mangunkusumo Hospital Madjid, Veinardi; Calvin, David; Purwoto, Gatot; Utami, Tofan Widya; Anggraeni, Tricia Dewi; Vidiawati, Dhanasari; Winarto, Hariyono
Makara Journal of Health Research Vol. 28, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction: Nausea and vomiting (NV) remain as side effects of chemotherapy, which has a detrimental effect on patients’ quality of life (QOL) and treatment adherence. This study aimed to determine the effect of chemotherapy-induced NV (CINV) on the QOL of patients with ovarian cancer treated with chemotherapy at Dr. Cipto Mangunkusumo Hospital (CMH). Methods: We conducted a cross-sectional study in patients with ovarian cancer receiving first-line chemotherapy regimens of carboplatin and paclitaxel. The European Organisation for Research and Treatment helped translate the Quality-of-Life Questionnaire-OV28 (QLQ-OV28) into Indonesian and tested it in a preliminary study. The approved Indonesian version of the QLQ-OV28, with the Quality-of-Life Questionnaire-C30 (QLQ-C30), was then used to evaluate QOL before and 1 week after chemotherapy. Results: Several symptom scales increased, whereas function scales decreased. Moreover, 72.5% had an increase in the NV symptom scale, whereas 67.5% had a decrease in patients’ scale after chemotherapy. CINV had a significant partial effect on reducing QOL (p = 0.047 and y = 12.208–0.432). Conclusions: CINV has a significant influence on lowering the QOL of patients with ovarian cancer undergoing first-line chemotherapy regimens with carboplatin and paclitaxel in CMH.
The Age as a Risk Factor for Advanced Stage in Cervical Cancer Patients at RSUPN Cipto Mangunkusumo 2019-2022: A Retrospective Multivariate Study Kusuma, Fitriyadi; Suryoadji, Kemal Akbar; Purwoto, Gatot; Wulandari, Anisa Saphira; Soloan, Garry; Sini, Kieran Pasha Ivan; Utami, Tofan Widya; Anggaraeni, Tricia Dewi; Putra, Andi Darma; Nuryanto, Kartiwa Hadi; Winarto, Hariyono
Indonesian Journal of Obstetrics and Gynecology Volume 13. No. 1 January 2025
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v13i1.2366

Abstract

Abstract Introduction: In 2020, cervical cancer ranked as the fourth most common cancer in women globally, with an incidence of 604,000 cases. In Indonesia, cervical cancer holds the second position among the most prevalent cancers in women. This study aims to evaluate the relationship between age and the occurrence of advanced-stage cervical cancer as a step towards effective prevention, early detection, and management. Methods: This research adopts a retrospective study design based on the Cancer Registration database of RSUPN Cipto Mangunkusumo, focusing on cervical cancer patients from 2019 to 2022. Multivariate analysis was conducted with age as the primary independent variable, considering parity and employment status in the analysis. The FIGO classification of cervical cancer stages was used to categorize patients into early and advanced stages. Results: Out of 512 cervical cancer cases, 492 were included in this study. The distribution of cervical cancer stages and the age distribution of patients is depicted in Figure 1 and Figure 2. The analysis of the relationship between cervical cancer stage, age, parity, and employment status is presented in Table 2. The association between age and cervical cancer stage is statistically significant (p<0.05) with an odds ratio of 2.13, particularly in individuals aged >54 years. Conclusion: Age over 54 years is a significant risk factor for advanced-stage cervical cancer. Although there is no significant association with parity and employment history, these findings support preventive and early detection efforts in the older population. Increased screening programs and education are expected to reduce cases of advanced-stage cervical cancer in the future.
Higher HIF-1alpha Level in Cervical Cancer Worsen the Outcome of Radiotherapy in Stage IIIB Squamous Cell Carcinoma of the Cervix Malano, Yoarva; Fitriyadi Kusuma; Prijanti, Ani Retno; Winarto, Hariyono; Anggraeni, Tricia Dewi; Utami, Tofan Widya; Adiyarianni, Ghina
Indonesian Journal of Obstetrics and Gynecology Volume 12 No. 2 April 2024
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32771/inajog.v12i2.1871

Abstract

Prevalensi Infeksi Human Papilloma Virus Risiko Tinggi Pada Wanita dengan Positif Human Immunodeficiency Virus di Dunia: Tinjauan Sistematis Berdasarkan Studi Terkini Kusuma, Fitriyadi; Suryoadji, Kemal Akbar; Abdullah, Muhammad Raoul Taufiq; Fauzi, Ahmad; Ridwan, Alifaturrasyid Syafaatullah; Purwoto, Gatot; Winarto, Hariyono; Anggraeni, Tricia Dewi; Utami, Tofan Widya
Jurnal Ilmiah Kesehatan Vol 22 No 02 (2023): Jurnal Ilmiah Kesehatan terbitan Agustus Volume 22 Nomor 02 Tahun 2023
Publisher : UIMA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33221/jikes.v22i02.2652

Abstract

Tipe Human Papilloma Virus (HPV) risiko tinggi merupakan etiologi dari kanker serviks yang menjadi kanker kedua terbesar pada wanita. Infeksi Human Immunodeficiency Virus (HIV) menjadi salah satu faktor risiko infeksi HPV. Pada pasien dengan HIV terjadi penurunan sistem imun yang dapat menyebabkan peningkatan risiko infeksi terlebih jika kadar CD4+ rendah. Untuk menelusuri seberapa banyak wanita dengan HIV yang terinfeksi virus HPV risiko tinggi pada berbagai penelitian terkini. Penelusuran dilakukan dengan metode systematic review menggunakan database Pubmed, Cochrane, dan ScienceDirect. Digunakan kata kunci “((HPV Positive) AND (HIV) AND (Cervical Cancer))”.Dalam systematic reviews ini, didapatkan hasil akhir 3 penelitian yang memenuhi kriteria inklusi. Di antaranya penelitian di Kenya tahun 2012 menunjukkan 52,6% dari 498 wanita dengan HIV terinfeksi HPV risiko tinggi, penelitian di Nigeria pada 2017 menunjukkan 29% dari 449 wanita dengan HIV terinfeksi HPV risiko tinggi dan juga terdapat hubungan signifikan antara HIV pada pasien wanita dengan infeksi HPV risiko tinggi dibandingkan dengan pasien wanita tanpa HIV dengan dengan OR 3,38 (95% CI 2,34–4,87, p < 0,001), dan penelitian di Nigeria tahun 2014 menunjukkan prevalensi HPV risiko tinggi lebih besar pada pasien dengan HIV positif (24,5%) dibandingkan HIV negatif (15,9%) secara bermakna (P<0,005; OR=1,7; 95% CI=1,1-2,7), serta terdapat penurunan dari prevalensi infeksi HPV risiko tinggi pada wanita dengan HIV positif apabila jumlah CD4 pasien lebih dari 500 sel/mm3 (OR = 0,7; 95% CI: 0,5-0,8). Prevalensi yang besar dan hubungan signifikan antara infeksi HPV risiko tinggi dengan HIV pada pasien wanita menunjukkan diperlukannya skrining HPV tipe risiko tinggi pada pasien wanita dengan HIV sebagai strategi pencegahan yang lebih awal terhadap kanker serviks dan dibutuhkan pemberian terapi yang rutin kepada wanita dengan HIV positif untuk memiliki angka CD4 >500 sel/mm3.
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN TINGKAT KEHAMILAN PASIEN HIPERPLASIA DAN KANKER ENDOMETRIUM: TINJAUAN SISTEMATIS DAN META-ANALISIS Kusuma, Fitriyadi; Suryoadji, Kemal Akbar; Wulandari, Anisa Saphira; Binathara, Geraldus Sigap Gung; Soloan, Garry; Sini, Kieran Pasha Ivan; Purwoto, Gatot; Utami, Tofan Widya; Anggaraeni, Tricia Dewi; Putra, Andi Darma; Nuryanto, Kartiwa Hadi; Winarto, Hariyono
Jurnal Ilmiah Kesehatan Vol 23 No 03 (2024): Jurnal Ilmiah Kesehatan terbitan Desember Volume 23 Nomor 03 Tahun 2024
Publisher : UIMA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33221/jikes.v23i03.3405

Abstract

Hiperplasia endometrium dan kanker endometrium adalah kondisi yang memengaruhi kesuburan wanita. Tujuan dari tinjauan sistematis dan meta-analisis ini adalah untuk mengevaluasi faktor-faktor yang berhubungan dengan tingkat kehamilan pada pasien dengan kondisi tersebut. Pencarian dilakukan di lima database utama: PubMed, Science Direct, Scopus, Embase, dan Cochrane Library. Dari 2.742 studi yang awalnya ditemukan, 7 studi memenuhi kriteria inklusi dan dianalisis lebih lanjut. Meta-analisis dilakukan untuk mengevaluasi efek terapi kombinasi Levonorgestrel-Releasing Intrauterine System (LNG-IUS) dengan progestin dan pengaruh indeks massa tubuh (BMI) terhadap tingkat kehamilan. Analisis gabungan dari dua studi yang membandingkan kombinasi LNG-IUS dengan progestin terhadap LNG-IUS saja menghasilkan Odds Ratio (OR) sebesar 1,54 [95% CI: 0,74–3,24], tanpa signifikansi statistik (p = 0,25). Untuk BMI, gabungan dua studi memberikan Risk Ratio (RR) sebesar 1,40 [95% CI: 0,93–2,10], juga tidak signifikan (p = 0,11). Heterogenitas yang rendah (I² = 0%) pada analisis terapi dan sedang (I² = 53%) pada analisis BMI menunjukkan konsistensi antarstudi. Meskipun ada tren peningkatan angka kehamilan dengan terapi kombinasi LNG-IUS dan progestin serta BMI ≥ 25, hasil meta-analisis ini belum menunjukkan signifikansi statistik. Penelitian lebih lanjut diperlukan untuk memperjelas faktor-faktor yang berhubungan dengan kehamilan pada pasien dengan hiperplasia dan kanker endometrium.
Gambaran Myelosupresi pada pasien Kanker Ovarium yang Menerima Kemoterapi Carboplatin-Paclitaxel di RSUPN Cipto Mangunkusumo Tahun 2018 Winarto, Hariyono; Wijaya, Andrew
Majalah Kedokteran Indonesia Vol 70 No 4 (2020): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.70.4-2020-160

Abstract

Background: Ovarian cancer has the highest mortality rate among other gynecologic cancers with poor prognosis due to unspecific symptoms. Ovarian cancer is mainly treated by surgical and chemotherapy combination. Despite its curative effect chemotherapy’s, myelosuppressive is a notable side effect and may impact the next cycle of chemotherapy. This study is aimed to record laboratory changes in chemotherapy recipient in Cipto Mangunkusumo Hospital.Methods: Hemoglobin, Absolute Neutrophil Count (ANC), and thrombocyte data are obtained from medical records whose received 6 cycles of Carboplatin-Paclitaxel from January-December 2018. Patients who received other chemotherapy and bone marrow metastasis were excluded.Results: Sixteen patients who completed 6 cycles were recorded. Baseline hemoglobin was 11.30±0.887 mg/dL and mean reduction was 0.29 g/dL per cycle. Mean ANC was 5,394.43±2096 cells/mm3, mean reduction was 543 cells/mm3 per cycle, and 5,35% developed neutropenia. Mean thrombocyte level was 34.225 cells/mm3 and 23% developed thrombocytopenia.Conclusions: Carboplatin-Paclitaxel’s effect on myelosuppression is prominent within the first cycle. Extra precaution must be done to prevent unwanted events.
Co-Authors Abdullah, Muhammad Raoul Taufiq Addin Trirahmanto Adiyarianni, Ghina Alexander AW Peters Amalia, Gassani Andi Darma Putra Andrew Wijaya Andrijono Andrijono Andrijono Andrijono Andrijono Anggaraeni, Tricia Dewi Anggraeni, Tricia Dewi Ani Retno Prijanti Antonius, Puja Agung Aria Kekalih Bambang Sutrisna Bambang Sutrisna Bambang Sutrisna Bambang Sutrisna Bambang Sutrisna Binathara, Geraldus Sigap Gung Bismarck J. Laihad Budiningsih Siregar Budiningsih Siregar Calvin, David Daud, Sulaeman Dhanasari Vidiawati Ediwibowo Ambari Ediwibowo Ambari Eka R Gunardi Erwin Rahakbauw Faisha Rahma, Melly Fauzi Ahmad Muda Ferry Sandra Fitriyadi Kusuma Gatot Purwoto Heru Prasetyo Indra, Ken Jamhari Jamhari Kartiwa H Nuryanto Kartiwa Hadi Nuryanto Kemal Akbar Suryoadji Ken Indra Laila Nuranna Laila Nuranna Madjid, Veinardi Malano, Yoarva Markus, Unedo H Markus, Unedo H Maulana, Muhammad Sobri Michael Adrian Muhammad Haekal Nana Supriana Nana Supriana Nuryanto, Kartiwa H Putra, Abdul Hafiidh Surya Rahakbauw, Erwin Ratnasari, Affi Angelia Ridwan, Alifaturrasyid Syafaatullah Rizky Humairah , Inas Sigit Purbadi Sini, Kieran Pasha Ivan Soloan, Garry Sri M. Sekarutami Sulaeman Daud Suryoadji, Kemal Akbar Tofan Widya Utami Tricia Dewi Anggraeni Unedo H Markus Utami, Tofan Widya Widya Utami, Tofan William Halim Wulandari, Anisa Saphira