Article Per Year (5 Year)
p-Index From 2021 - 2026
2.386
P-Index
This Author published in this journals
All Journal Bioma : Berkala Ilmiah Biologi IPTEK Journal of Proceedings Series Jurnal Kimia Riset Indonesian Journal of Chemical Science Jurnal Surya Medika Biosaintifika: Journal of Biology & Biology Education KLOROFIL: Jurnal Ilmu Biologi dan Terapan Gorontalo Agriculture Technology Journal Jurnal Respirologi Indonesia Jurnal Abdi Insani Spizaetus: Jurnal Biologi dan Pendidikan Biologi SIMBIOSA Humanism : Jurnal Pengabdian Masyarakat KLOROFIL: Jurnal Ilmu Biologi dan Terapan Journal Pharmasci (Journal of Pharmacy and Science) International Journal of Community Service Journal of Experimental and Clinical Pharmacy (JECP) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Prosiding Seminar Nasional Biologi Jurnal Komunitas Farmasi Nasional
Umarudin, Umarudin
Akademi Farmasi Surabaya
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

Published : 26 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 26 Documents
Search

 1   2   3 
Toxicity of Miana Leaf (Coleus blumei) Extract Against Houseflies (Musca domestica) Surahmaida, Surahmaida; Umarudin, Umarudin
Biosaintifika: Journal of Biology & Biology Education Vol 11, No 2 (2019): August 2019
Publisher : Department of Biology, Faculty of Mathematics and Sciences, Semarang State University . Ro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (469.62 KB) | DOI: 10.15294/biosaintifika.v11i2.19402

Abstract

Houseflies (Musca domestica) is an disease-carrying insect  that plays an important role in the spread of disease in humans and animals. One way to control houseflies is using Miana leaves (Coleus blumei) as botanical pesticide. The purpose of this study was to determine the chemical compounds contained in Miana leaf as well as determine the optimal concentration of Miana leaf extract in causing knockdown effect in houseflies. Miana leaf fine powder was soaked with methanol (maceration) for 3 days followed byphytochemical screening (chemical reagents and Gas Chromatography Mass Spectrophotometry (GCMS) and anti-houseflies toxicity tests. Testing of methanolic extract of Miana leaves was made in the form of spray using the knockdown method at concentrations of 5%, 10%, 20%, 30% and 40% and observed in 5, 10 and 15 minutes. The results of phytochemical screening with chemical reagents showed that the extract contained alkaloids, tannins, flavonoids, saponins and terpenoids; while the results of GCMS analysis showed 8 bioactive compounds. The results of the study revealed that at a concentration of 30% and 40%, methanolic extract of Miana leaves could result in a knockdown effect that was accompanied by death with a percentage value of 100% in the first 5 minutes of observation. This research shows that methanolic extract of Miana leaves can be used as an alternative to botanical pesticides in controlling houseflies (Musca domestica).
Efektivitas Tanaman Lemna (Lemna perpusilla Torr) Sebagai Agen Fitoremediasi Pada Keramba Jaring Apung (KJA) Disekitar Tanjungmas Semarang U, Umarudin; Nur, Jumriah; Wulandari, Ayu; Izzati, Munifatul
Bioma : Berkala Ilmiah Biologi Vol. 17, No.1, Tahun 2015
Publisher : Departemen Biologi, Fakultas Sains dan Matematika, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (650.505 KB) | DOI: 10.14710/bioma.17.1.1-8

Abstract

The port of Tanjung Emas, Semarang as the main port in Central Java that have activity increases pollution impact. Hence the need for special attention and handling by using aquatic plants Lemna perpusilla. The purpose of this research is to know the physical condition of floating around the net keramba Tanjungmas city of Semarang. Designing the application fitoremediasi on floating around the net keramba Tanjungmas city of Semarang and Knowing the prospects of development of fitoremidiasi. This paper uses a case study research methods (case study), which this method has the goal to provide a detailed description of the background, traits and characters typical of cases of water are there in KJA around the Tanjugmas City of Semarang by taking the research object. While this research is the observation and interview is open ended. So that the data obtained indicate that the physical condition of floating around the net keramba Tanjungmas Semarang blackened water greenish colours, smells, and oily. Application design fitoremidiasi by Lemna perpusilla utilize water plants and fish seed banding continued with the observed results. As well as direct application on the KJA in the waters of Tanjung Mas with lemna and seed density setting fish whitefish. Fitoremidiasi development prospects by looking at opportunities to fish bandeng and Lemna perpusilla. Key words: Fitoremediasi, KJA, Fish Bandeng, Lemna perpusilla, Pollution.  
Identifikasi dan Analisa Senyawa Kimia Ekstrak Daun Miana (Coleus blumei) Surahmaida, Surahmaida; Umarudin, Umarudin
IPTEK Journal of Proceedings Series No 4 (2019): Seminar Nasional Kimia (SENAKI) XV 2019
Publisher : Institut Teknologi Sepuluh Nopember

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (674.976 KB) | DOI: 10.12962/j23546026.y2019i4.6115

Abstract

Miana (Coleus blumei) atau yang lebih dikenal masyarakat dengan sebutan “Wiyono” termasuk salah satu tanaman hias dengan beragam varietas dedaunan yang berwarna-warni dan berkhasiat sebagai obat bisul atau memar. Tujuan penelitian adalah untuk mengidentifikasi dan menganalisis senyawa kimia yang terkandung dalam daun Miana. Daun Miana dicuci, dikeringkan, lalu diblender hingga menjadi serbuk halus. Serbuk halus daun Miana direndam ke dalam pelarut n-heksana selama 3 hari dengan 2 kali ulangan. Ekstrak n-heksana daun Miana dianalisis menggunakan Gas Chromatography Mass Spectrophotometry (GCMS). Hasil senyawa kimia yang teridentifikasi yaitu hexahydro-3H-1[2’trifluoromethyl]-6’[4”-trifluoromethylphenyl]-; 2-methylthiophene; 1-(4-phenylcyclohexyl)-1-hexanone; (Z)-3-heptadecen-5-yne; anilino-5H-dibenzo[b,e][1,4]diazepine; octadecane; silicone grease, siliconfett; dotriacontane; hexadecahydro-pyrene; aristolone dan triacontane. Dapat disimpulkan bahwa senyawa-senyawa kimia tersebut memiliki aktivitas biologi dan farmakologis yang berguna bagi manusia.
Porcine Detection on Anti-Covid 19 Immunity Gelatin Capsules Sold at Market X in North Surabaya Using Quartz Crystal Microbalance (QCM) Sensors Syukrianto, Syukrianto; Umarudin, Umarudin; Madurani, Kartika Anoraga; Kurniawan, Fredy
Indonesian Journal of Chemical Science Vol 10 No 3 (2021)
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/ijcs.v10i3.50456

Abstract

Immune gelatin capsules, which have not been fully indicated on the packaging, need to be investigated porcine or bovine using a Quartz crystal microbalance (QCM) tool. The advantages of the QCM tool are sensitivity to the crystal oscillation frequency at a specific temperature, humidity, pressure, speed, and vibration, which will make this piezoelectric oscillator used as a sensor with a high accuracy level. The purpose of this study was to determine the content of porcine (pork) or bovine (beef) in anticovi19 immunity gelatin capsules sold at market X, North Surabaya. The method used to distinguish pork gelatin and beef gelatin is a Quartz crystal microbalance (QCM) tool. In this study, the detection of anti-covid19 immunity gelatin capsules was carried out using a QCM tool. This research method was carried out in a factual experimental manner, and sampling with the quota technique was 3 grams for each sample with a different brand. The results of research conducted on four samples with other brands originating from the market X area of North Surabaya showed the detection results of 2 samples with adverse effects (-), and two samples with positive results (-), meaning that the negative samples contained beef gelatin (bovine) and the positive sample contains pork (porcine). A decrease in frequency characterized the sample of immunity gelatin capsules containing bovine gelatin. In contrast, the sample of immunity gelatin capsules containing porcine gelatin was characterized by increased frequency.
Pengaruh Variasi Kombinasi Konsentrasi Surfaktan Non Ionik (Span 60 Dan Peg-40 Hco) Terhadap Stabilitas Fisik Mikroemulsi Koenzym Q10 Silvi Ayu Wulansari; Umarudin Umarudin
Jurnal Surya Medika (JSM) Vol 6 No 1 (2020): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v6i1.1534

Abstract

Coenzyme Q10 is a compound that functions as an antioxidant with a large molecular weight of 863.36 g / mol and has lipophilic properties. This makes coenzyme Q10 need to be formulated to improve the solubility of the material and the delivery system in the skin. This study aims to determine the effect of various combinations of non-ionic surfactant concentrations (span 60 and PEG-40 HCO) on the physical stability of microemulsions. In this study Coenzyme, Q10 was formulated in oil-type microemulsion preparations in water. The oil used as the oil phase is rice bran oil with a combination of surfactant span 60 and PEG-40 HCO and 96% ethanol as a cosurfactant. the microemulsion was made in 4 microemulsion formulas namely FI, F2, F3, and F4, each formula was made 3 replications. Microemulsion preparations were evaluated after 24 hours after the preparations were made, observations made included organoleptic (shape, color, and phase formed), pH, viscosity, droplet size, zeta potential, and polydispersity index before and after centrifugation test with 10,000 rpm for 30 minutes. The research data were processed statistically using the Kruskal-Wallis analysis and Mann-Whitney follow-up tests. The results showed that the surfactant concentration affected physical characteristics (viscosity, droplet size, zeta potential, and polydispersity index) with a significantly different result (p <0.05) but the surfactant concentration did not affect the pH with the results not significantly different (p> 0, 05).
Senyawa Bioaktif Daun Kumis Kucing (Orthosiphon stamineus) Surahmaida Surahmaida; Umarudin Umarudin; Junairiah Junairiah
Jurnal Kimia Riset Vol. 4 No. 1 (2019): Juni
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (171.619 KB) | DOI: 10.20473/jkr.v4i1.13176

Abstract

AbstrakDaun kumis kucing (Orthosiphon stamineus) umumnya digunakan sebagai tanaman obat keluarga, hal ini diduga karena senyawa bioaktif yang terkandung didalamnya. Tujuan penelitian ini untuk mengetahui senyawa bioaktif ekstrak n-heksana daun kumis kucing (Orthosiphon stamineus) menggunakan GCMS. Hasil senyawa bioaktif yang teridentifikasi ekstrak n-heksana daun kumis kucing mengandung 1,1-Dicyclopentylethane; Bicyclo[3.2.0]hept-2,6-diene-1,2,3,4,4,5,6-d(7); n-Butyl palmitate; 1-oxo03.alpa.-(4-methyl-3-pentenyl)-6.alpa.-methyl-6a.alpa.-carbomethoxy-1,3,3a.alpa.,6a-tetrahydrocyclopenta[c]furan;  1,1,3,3,5,5,7,7,9,9,11,11,13,13-tetradecamethylheptasiloxane; 1,4-bis(trimethylsilyl)-benzene dan Silicone grease, Siliconfett. Senyawa-senyawa bioaktif ekstrak n-heksana daun kumis kucing tersebut kemudian dianalisis aktivitas biologi dan farmakologisnya. Katakunci: Orthosiphon stamineus, senyawa bioaktif, GCMS AbstractThe leaves of cat whiskers (Orthosiphon stamineus) are generally used as family medicinal plants, this is thought to be due to the bioactive compounds contained therein. The purpose of this study was to find out the bioactive compounds of n-hexane extract of cat whiskers (Orthosiphon stamineus) using GCMS. The results of bioactive compounds identified with n-hexane extract of cat whiskers containing 1,1-Dicyclopentylethane; Bicyclo[3.2.0]hept-2,6-diene-1,2,3,4,4,5,6-d(7); n-Butyl palmitate; 1-oxo03.alpa.-(4-methyl-3-pentenyl)-6.alpa.-methyl-6a.alpa.-carbomethoxy-1,3,3a.alpa.,6a-tetrahydrocyclopenta[c]furan;  1,1,3,3,5,5,7,7,9,9,11,11,13,13-tetradecamethylheptasiloxane; 1,4-bis(trimethylsilyl)-benzene and Silicone grease, Siliconfett. The bioactive compounds of the n-hexane extract of the cat's whiskers leaves were then analyzed for their biological and pharmacological activities. Keywords: Orthosiphon stamineus, bioactive compound, GCMS
The Correlation Between Interleukin-10 1082G/A Gene Polimorphism Late Onset with Nephrotoxicity Secondary to Antituberculosis Treatment in Multidrug Resistant Tuberculosis Patients Harsini Harsini; Reviono Reviono; Umarudin Umarudin
Jurnal Respirologi Indonesia Vol 39, No 4 (2019)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v39i4.71

Abstract

Backgrounds: Tuberculosis controlling programme has become more complex with MDR-TB problem. Interleukin 10 (IL-10) 1082G/A gene polimorphism correlates with IL-10 secretion as anti-inflammatory cytokine which plays important role in pathogenesis of MDR-TB infection. The management of MDR-TB which used aminoglycosides could cause nephrotoxic effect to the patients. The protective role of IL-10 from IL-10 1082 G/A genotype to nephrotoxicity due to kanamycin still becomes a prolem nowadays. Methods: This study was a retorspective cohort study of MDR-TB patients who underwent treatment in Dr. Moewardi Hospital in 2011-2015. Results: Subjects of the study were 89 MDR-TB patients with IL-10 1082 G/A genotype polimorphism. The proportions of IL-10 1082 G/A genotype were AA genotype of 13.48%, GG of 4.49%, and GA of 82.2%. Statistic test showed that the onset of nephrotoxicity in GG genotype was faster than GA and AA genotype Conclusions: Interleukin 10 1082 G/A gene polymorphism had no significant correlation with nephrotoxicity onset in MDR-TB patients treated with kanamycin in Dr. Moewardi hospital. (J Respir Indo. 2019; 39(4): 215-9)
Uji Antimikroba Daging Buah (Carica pubescens) Matang Terhadap Bakteri Staphylococcus aureus Metode Kirby Bauer Secara In Vitro Umarudin Umarudin; Floreta Fiska Yuliarni
SIMBIOSA Vol 8, No 2 (2019): JURNAL SIMBIOSA
Publisher : Universitas Riau Kepulauan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33373/sim-bio.v8i2.2043

Abstract

Staphylococcus aureus dapat menyebabkan infeksi kulit seperti bisul atau abses dan jerawat. Pengunaan antibiotik yang tidak tepat menyebabkan munculnya S. aureus yang resisten terhadap antibiotik karena adanya perubahan genetik. Permasalahan yang disebabkan akibat penggunaan antibiotik yang tidak tepat tersebut menimbulkan upaya eksplorasi senyawa antibakteri yang lebih efektif dengan dampak yang minimal. Salah satu tanaman yang bersifat sebagai antibakteri adalah daging buah karika (Carica pubescens). Penelitian ini dilakukan secara true eksperimental. S. aureus diperoleh dari laboratorium Universitas Airlangga dan diidentifikasi berdasarkan sifat biakan, pewarnaan Gram, uji biokimiawi dan uji gula-gula. Isolat selanjutnya diuji antimikroba terhadap ekstrak daging buah C. pubescens. Hasil penelitian menunjukkan bahwa bakteri yang tumbuh, dapat memfermentasi plat mannitol salt agar, sel berbentuk bulat bergerombol, bersifat Gram +, dapat memfermentasi maltosa dan laktosa, dapat menkoagulasi plasma kelinci dan bereaksi positif terhadap uji clumping faktor dan uji Voges Proskouer. Pada penelitian ini, hasil uji menunjukkan bahwa ekstrak daging buah Carica pubescens dengan konsentrasi 20%, 40%, dan 60% memiliki daya hambat terhadap Staphylococcus aureus. Daya hambat terbesar terdapat pada konsentrasi 60%. Semakin kecil konsentrasi ekstrak C. pubescens, semakin kecil daya hambatnya terhadap S. aureus.
Aplikasi Hand Sanitizer Kitosan Cangkang Bekicot Sebagai Antibakteri dan Upaya Preventif Covid 19 Umarudin Umarudin; Surahmaida Surahmaida; Syukrianto Syukrianto; Silvi Ayu Wulansari; Siti Nurhaliza
SIMBIOSA Vol 9, No 2 (2020): JURNAL SIMBIOSA
Publisher : Universitas Riau Kepulauan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33373/sim-bio.v9i2.2669

Abstract

Salah satu infeksi akibat bakteri yang dapat menyebabkan saluran pernapasan  adalah Klebsiella pneumonia. Desain yang digunnakan pada penelitian ini adalah true eksperimental. Tahapan penelitian dengan isolasi kitosan cangkang bekicot yaitu deproteinasi, demineralisasi, depigmentasi, dan deasetilasi, pembuatan hand sanitizer kitosan cangkang bekicot. Analisa data yang digunakan deskriptif kualitatif dan kuantatif untuk uji evaluasi organoleptis dan jumlah koloni bakteri dan uji ANOVA satu arah jika terdapat perbedaan dilakukan uji lanjut dengan uji LSD. Hasil penelitian menunjukan bahwa uji organoleptis hand sanitizer selama 28 hari dan didapatkan hasil sesuai spesifikasi yaitu berbentuk gel, warna transparan dan tidak ada aroma yang dikeluarkan, pH sediaan hand sanitizer sesuai dengan standart pH kulit, sediaan hand sanitizer kitosan cangkang bekicot homogen, jumlah koloni formula 2 (6%) dengan rata-rata 0,67 koloni, 3% dengan rata-rata 2,67 koloni lebih efektife alam menghambat pertumbuhan bakteri jika dibandingkan dengan K (-) dengan rata-rata 107,67. Perlakuan hand sanitizer 3% berbeda nyata secara signifikan dengan kontrol dan 6%, perlakuan hand sanitizer 6% berbeda nyata signifikan dengan kontrol dan 3%. Semakin tinggi konsentrasi cangkang bekicot semakin besar kemampuan daya hambat dan bersifat bakterisidal.
Isolasi, Identifikasi, Dan Uji Antibakteri Kitosan Cangkang Bekicot (Achatina fulica) Terhadap Staphylococcus aureus dari Penderita Ulkus Diabetikum Umarudin Umarudin; Surahmaida Surahmaida
SIMBIOSA Vol 8, No 1 (2019): JURNAL SIMBIOSA
Publisher : Universitas Riau Kepulauan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33373/sim-bio.v8i1.1894

Abstract

Salah satu bakteri penyebab ulkus diabetikum adalah Staphylococcus aureus. Pengunaan antibiotik yang tidak tepat menyebabkan munculnya S. aureus yang resisten terhadap antibiotik atau bertahan hidup karena adanya perubahan genetic. Bahan alam yang memiliki sifat sebagai antibakteri adalah kitosan cangkang bekicot.Penelitian ini bertujuan untuk melakukan isolasi dan uji antibakteri kitosan cangkang bekicot terhadap Staphylococcus aureus dari penderita ulkus diabetikum dan juga dilakukan uji sensitifitas S. aureus terhadap kitosan cangkang bekicot. Pada penelitian inidilakukan secara true eksperimental. S. aureus diisolasi dari penderita ulkus diabetikum dan diidentifikasi berdasarkan sifat biakan, pewarnaan Gram, uji biokimiawi dan uji gula-gula. Isolat selanjutnya diuji sensitifitasnya terhadap kitosan cangkang bekicot. Hasil penelitian menunjukkan bahwa isolasi bakteri yang tumbuh dan dapat memfermentasi plat mannitol salt agar, sel berbentuk bulat bergerombol, bersifat Gram +, memfermentasi maltosa dan laktosa, mengkoagulasi plasma kelinci dan bereaksi positif terhadap uji clumping faktor dan Voges Proskouer. Pada penelitian ini, hasil uji terhadap kitosan cangkang bekicot pada kosentrasi 300-700 ppm adalah sensitif. Penelitian ini dapat disimpulkan bahwa penderita ulkus diabetikum yang diidentifikasi adalah Staphylococcus aureus. Isolat S. aureus sebagian besar sensitif terhadap kitosan cangkang bekicot (Achatina fulica).
Co-Authors Adinirekso, Gidion Anidnya, Widya Dara Anindya, Widya Dara Anisa Rizki Amalia Aristyawan, Andhika Dwi Ayu Wulandari Bawanda, Edward Melfin Devianti, Vika Ayu Evy Aryanti Frans Assa, Adrie Fredy Kurniawan Galuh Gondo Kusumo Harsini Harsini Johanis Rumambi, Freddy Jumriah Nur, Jumriah Junairiah Junairiah Lailatus Sa’diyah Madurani, Kartika Anoraga Mochammad Sulton Aziz Irawan Munifatul Izzati Ramadhan Renaisansa Reviono Reviono Sa’diyah, Lailatus Sa’diyah, Lailatus Siti Nurhaliza Surahmaida, Surahmaida Syafitri, Meyke Herina Syukrianto Syukrianto Syukrianto Syukrianto, Syukrianto Ulfa, Ninik Mas Widjaja, Daniel Wulansari, Silvi ayu Yuliarni, Floreta Fiska Yuyun Widayati