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All Journal Jurnal Anestesiologi Indonesia Jurnal Anestesi Perioperatif Biology, Medicine, & Natural Product Chemistry Abdimas Talenta : Jurnal Pengabdian Kepada Masyarakat Jurnal Biomedika dan Kesehatan Journal SAGO Gizi dan Kesehatan Prosiding Konferensi Nasional PKM-CSR Majalah Anestesia & Critical Care (MACC)
Yunanda, Yuki
Departemen Ilmu Kedokteran Komunitas, Fakultas Kedokteran, Universitas Sumatera Utara, Medan
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Control & Systems Engineering Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences

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EDUKASI DAN SOSIALISASI PENCEGAHAN PENYEBARAN COVID-19 PADA SISWA DAN GURU SEKOLAH MENENGAH PERTAMA BERBASIS USAHA KESEHATAN SEKOLAH (UKS) DI KECAMATAN BINJAI KABUPATEN LANGKAT, PROVINSI SUMATERA UTARA, TAHUN 2020 Rina Amelia; Arlinda Sari Wahyuni; Yuki Yunanda; , Putri Chairani Eyanoer; Juliandi Harahap; Isti Ilmiati Fujiati
Prosiding Konferensi Nasional Pengabdian Kepada Masyarakat dan Corporate Social Responsibility (PKM-CSR) Vol 3 (2020): Peran Perguruan Tinggi dan Dunia Usaha Dalam Pemberdayaan Masyarakat Untuk Menyongsong
Publisher : Asosiasi Sinergi Pengabdi dan Pemberdaya Indonesia (ASPPI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (81.842 KB) | DOI: 10.37695/pkmcsr.v3i0.1040

Abstract

The coronavirus pandemic (COVID-19) is designated as a Public Health Emergency that is troubling the world, much remains unknown about the virus that causes COVID-19, but in general, this virus is transmitted through direct contact with droplets from the respiratory tract of an infected person (which exits through coughs). And sneezes). People can also become infected by touching a surface contaminated with this virus and then touching their face (eg, eyes, nose, mouth). The school health program (SHP) is a health program implemented at the school level. The main activities of SHP are carried out through health education, health services, and fostering a healthy school environment with the primary target of students, educators, educators, and the school community. Efforts to maintain health can be started from the school environment, which emphasizes changing behavior. Therefore this SHP program is essential because it includes early health education. This community service aims to provide education and socialization to prevent the spread of the COVID-19 virus to teachers and students based on UKS at Amanah SMPS, Binjai District, Langkat Regency. Before being given education, assessing the COVID-19 prevention behavior that they have implemented is carried out using a valid questionnaire. Then proceed with educational activities. The educational method carried out was by lecturing and discussing the prevention of COVID-19 and simulating the proper use of masks, after which several participants were asked to practice it and witnessed by other participants. It is hoped that with this community, serving students and teachers will increase their understanding and be able to prevent COVID-19 both for themselves and prevention in the community.
Perbandingan bupivacain 0,5% 15 mg dan fentanil 25 mcg dengna bupivacain 0,5% 15 mg terhadap nilai oksigenasi pada pasien dengan anestesi spinal Ahmad Ridho Lubis; Rr Sinta Irina; Rommy F. Nadeak; Yuki Yunanda
Jurnal SAGO Gizi dan Kesehatan Vol 5, No 1 (2023): Desember
Publisher : Poltekkes Kemenkes Aceh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30867/gikes.v5i1.1286

Abstract

Background: Spinal anesthesia is a safe anesthetic technique for elective and emergency surgeries. Spinal anesthesia adversely affects cerebral oxygenation, especially when fentanyl is administered as an adjuvant to spinal anesthesia.Objectives: To determine the difference in cerebral oxygenation values between patients undergoing spinal anesthesia using bupivacaine 0,5% with fentanyl and bupivacaine 0,5% in patients undergoing spinal anesthesia.Methods: This was an analytic post-test experiment with a cross-sectional design. This study was conducted at the Haji Adam Malik Hospital Medan, with a total sample of 36 patients. The research group was divided into groups that received bupivacaine 0,5% 15 mg and bupivacaine 0,5% 15 mg plus fentanyl 25 µg. The rSO2 value was assessed before spinal action (T0), shortly after spinal anesthesia (T1), and 15 min after spinal anesthesia (T2). Near-infrared spectroscopy was used as the measurement instrument. Data to be collected were analyzed with a bivariate, independent T-test and Mann-Whitney test with a 95% confidence interval (CI).Results: The average rSO2 values of patients who received bupivacaine were 64,0% on the right and 65,1% on the right and left sides, respectively. The average rSO2 values of patients who received bupivacaine were 74,8% on the right and 76,1% on the left. There was a significant difference in blood pressure and rSO2 values in patients who received 0,5% bupivacaine spinal anesthesia with 0,5% bupivacaine added to 25 µg fentanyl (p <0,05).Conclusion: There was a significant difference in rSO2 values between patients who received 0,5% bupivacaine spinal anesthesia with 0,5% bupivacaine plus 25 µg fentanyl. 
Perbandingan Vasopressin dan Norephinephrine sebagai Vasopressor pada Pasien Syok Sepsis Andrio Farel Edward Gultom; Rommy F. Nadeak; Tasrif Hamdi; Yuki Yunanda
Jurnal Anestesi Perioperatif Vol 12, No 2 (2024)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15851/jap.v12n2.3739

Abstract

Sepsis menyebabkan kematian terbesar, tingkat mortalitas sepsis tinggi dan dapat mencapai 50% pada syok sepsis. Tatalaksana resusitasi pada syok sepsis menggunakan vasopresor. norepinephrine saat ini adalah rekomendasi utama pada syok sepsis, vasopressin digunakan sebagai obat lini kedua untuk mengurangi efek samping yang disebabkan oleh obat seperti norephinephrine, dan juga membantu pada keadaan syok resisten-katekolamin. Penelitian ini merupakan penelitian uji klinis dengan metode acak tersamar ganda. Penelitian ini bertujuan untuk mengetahui perbandingan penggunaan vasopressin dan norephinephrine sebagai vasopresor pada pasien syok sepsis di ICU RSUP H. Adam Malik Medan. Pencatatan hasil dilakukan setelah diberikan intervensi (T0), 6 jam (T1), dan 24 jam (T2). Sampel yang diperoleh pada penelitian ini berjumlah 36 pasien dengan 13 pasien dalam kelompok vasopressin dan 13 pasien dalam kelompok norepinephrine. Rerata TDS, TDD dan Mean Arterial Pressure (MAP) T0, T1, dan T2 kelompok norepinephrine lebih tinggi bila dibanding dengan dengan kelompok vasopressin. pH pada kelompok norepinephrine lebih rendah bila dibanding dengan dengan kelompok vasopressin. Simpulan, terdapat perbedaan yang signifikan antara norepinephrine dengan vasopressin sebagai vasopressor, dimana MAP dan kadar laktat, pada kelompok Norepinephrine lebih tinggi bila dibanding dengan dengan vasopressin. Sedangkan pH didapatkan lebih rendah pada kelompok norepinpehrine pada jam ke-24 dibanding dengan kelompok vasopressin.
PERBANDINGAN EFIKASI MGSO4 DENGAN KETAMIN SEBAGAI ADJUVAN MULTIMODAL ANALGESIA PASKA OPERASI SEKSIO SESARIA Eka Setia Miharja; Mhd Ihsan; Dadik Wahyu Wijaya; Yuki Yunanda
Jurnal Anestesi Perioperatif Vol 11, No 3 (2023)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15851/jap.v11n3.3652

Abstract

Nyeri perut pascaseksio sesaria tampaknya menjadi masalah yang signifikan, namun cukup bervariasi, berbagai modalitas analgesia diketahui dapat digunakan sebagai analgesia pascaoperasi. Salah satunya adalah ketamin dan magnesium sulfat yang sering digunakan sebagai tambahan untuk analgesik pascaoperasi. Penelitian ini merupakan studi randomized control trial (RCT) dilakukan selama Agustus–September 2023. Sampel merupakan pasien hamil yang akan menjalani pembedahan seksio sesaria dalam anetesi spinal. Penelitian dibagi menjadi 3 kelompok, MgSO4, ketamin, dan kontrol. Pada periode pascaoperasi, kelompok MgSO4 diberikan infus MgSO4 20 mg/kg/jam, kelompok ketamin menerima infus ketamine 0,2 mg/kg/jam selama 12 jam. Lalu, dilakukan penilaian skala nyeri pascaoperasi Penelitian terdiri dari 30 sampel, yaitu 10 sampel setiap kelompok. Berdasarkan skala nyeri istirahat dan aktivitas didapatkan perbedaan bermakna secara statistik pada pemantauan jam ke-12 dan jam ke-24, p<0,05. Sementara pada perubahan hemodinamik selama pemantauan tidak didapatkan perbedaan bermakna pada perubahan MAP dan detak jantung pada seluruh waktu pemantauan, p>0,05. Didapatkan 2 kejadian sedasi pada perlakuan ketamin dan 8 sampel memerlukan rescue opioid. Terdapat perbedaan efikasi ketamin dibanding dengan magnesium sulfat sebagai adjuvan analgesia pascaoperasi. Ketamin memberikan efek analgesia yang lebih baik dibanding dengan magnesium sulfat. 
PERBANDINGAN FLUOKSETIN 20 MG DENGAN AMITRIPTILIN 12,5 MG SEBAGAI ADJUVAN KOMBINASI PARASETAMOL DAN MORFIN DALAM MENGURANGI NYERI PADA PASIEN NYERI KANKER Ramud, Samawi Husein; Hamdi, Tasrif; Bangun, Chrismas Gideon; Yunanda, Yuki
Jurnal Anestesi Perioperatif Vol 12, No 3 (2024)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15851/jap.v12n3.3628

Abstract

Data WHO menunjukkan bahwa 30–40% pasien kanker mengalami nyeri sedang atau berat. Empat kelas obat antidepresan dapat dipakai dalam pengobatan nyeri neuropatik. Penelitian ini bertujuan untuk mengetahui perbandingan fluoksetin 20 mg dengan amitriptilin 12,5 mg sebagai adjuvant kombinasi parasetamol 1000 mg dalam mengurangi gejala nyeri pada pasien nyeri kanker. Penelitian dilaksanakan sejak Juli–September 2023 di klinik nyeri Rumah Sakit Umum Pusat Haji Adam Malik Medan. Penelitian ini adalah uji klinis acak tersamar. Sebanyak 40 subjek dibagi dalam 2 kelompok. Kelompok A (n=20) mendapat fluoksetin, morfin dan parasetamol, sedangkan kelompok B (n=20) mendapat amitriptilin, morfin dan parasetamol. Skor nyeri pada subjek diukur dengan menggunakan PainDETECT. Data dianalisis secara univariat dan bivariat. Data bivariat dianalisis dengan uji Chi-Square, T-Test Independent, T-Test Paired dan Mann-Whitney. Terdapat penurunan skor numeric rating scale dan PainDETECT yang signifikan antara sebelum dan setelah pemberian fluoksetin maupun amitriptilin dengan nilai p<0,05. Kelompok fluoksetin maupun amitriptilin dapat menurunkan skor numeric rating scale dan PainDETECT secara statistik, akan tetapi tidak bermakna secara klinis.
PERBANDINGAN NEBULISASI LIDOKAIN 2% DAN SPRAY LIDOKAIN 10% DALAM MENCEGAH REFLEKS BATUK PADA PASIEN BRONKOSKOPI DENGAN SEDASI DI RSUP HAJI ADAM MALIK MEDAN Pohan, Alfindy Maulana; Tanjung, Qadri Fauzi; Silaen, Ester Lantika Ronauli; Yunanda, Yuki
Jurnal Anestesi Perioperatif Vol 12, No 3 (2024)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15851/jap.v12n3.4010

Abstract

Keluhan batuk sering muncul pada pasien yang menjalani bronkoskopi akibat adanya trauma mekanik pada dinding saluran napas. Lidokain digunakan pada bronkoskopi untuk menekan refleks batuk. Penelitian ini bertujuan menilai efek lidokain yang diberikan secara nebulisasi dan spray terhadap refleks batuk pada pasien bronkoskopi. Desain penelitian randomized control trial dilaksanakan di RSUP Haji Adam Malik bulan Agustus sampai dengan September 2023 pada pasien bronkoskopi dengan sedasi. Sampel yang diperoleh 36 pasien yang dibagi menjadi 2 kelompok yaitu kelompok yang mendapat spray Lidokain 10% dan kelompok yang mendapatkan nebulisasi lidokain 2%. Variabel yang diteliti adalah derajat batuk. Analisis statistik yang digunakan adalah mann whitney. Berdasarkan penelitian yang dilakukan terdapat perbedaan derajat batuk yang bermakna pada pada menit ke-15, menit ke-30 dan postperlakuan (p<0,05). Pada kelompok nebulisasi Lidokain 2% derajat batuk lebih rendah dibanding dengan pada kelompok spray Lidokain 10%. Simpulan: Pemberian nebulisasi lidokain 2% lebih efektif menekan derajat batuk dibanding dengan spray lidokain 10% pada tindakan bronkoskopi dengan sedasi.
Comparison of Fluoxetine (20 Mg) and Amitriptyline (12.5 Mg) As Adjuvants for The Combination of Paracetamol and Morphine in Cancer Patients' Pain Relief Ramud, Samawi Husein; Hamdi, Tasrif; Bangun, Chrismas Gideon; Yunanda, Yuki
JAI (Jurnal Anestesiologi Indonesia) Vol 17, No 1 (2025): JAI (Jurnal Anestesiologi Indonesia)
Publisher : Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jai.v0i0.59070

Abstract

Background: Pain is one of the most common symptoms in cancer which affects 30–50% of patients on average and rises to 70–90% in cases of advanced disease. As cancer advances, so does the frequency of discomfort associated with the illness. When cancer is detected in its terminal stage, 30–40% of patients report experiencing moderate pain, and 60–100% report experiencing severe pain. Tricyclic antidepressants (TCAs), selective serotonin and norepinephrine reuptake inhibitors (SNRIs), selective serotonin reuptake inhibitors (SSRIs), and monoamine oxidase inhibitors (MAOIs) are the four families of antidepressant medications that have been investigated for use in the treatment of neuropathic pain.Objective: This research was conducted at the pain clinic of Adam Malik Hospital, this study intends to compare the effectiveness of fluoxetine with amitriptyline as an adjuvant to the combination of paracetamol and morphine in reducing pain symptoms in cancer patients.Methods: This study was designed as a randomized, double-blind clinical experiment. The study was carried out in 2023 between July and September. Two groups of forty research participants receiving outpatient care at the pain clinic were formed. Fluoxetine, morphine, and paracetamol were administered to group A (n = 20), whereas amitriptyline, morphine, and paracetamol were administered to group B (n = 20). PainDETECT was used to measure the subjects' pain scores. Both univariate and bivariate data analysis was done. The Chi-Square test, Independent T-test, Paired T-test, and Mann-Whitney were used to examine the bivariate data.Result: The delivery of amitriptyline and fluoxetine resulted in a substantial reduction in PainDETECT scores, with a p-value of less than 0.05.Conclusion: This study show that PainDETECT score was statistically reduced in both the fluoxetine and amitriptyline groups but the reduction was not clinically meaningful because the target score drop was less than 4 on a scale of 0–10, or a 50% reduction in pain.
Perbandingan Preloading Cairan 20 cc/kgBB dan 30 cc/kgBB setelah One-Hour Bundle terhadap Nilai Laktat pada Pasien Sepsis di Ruang ICU Rendi Sidiq; Hamdi, Tasrif; Bisono, Luwih; Yunanda, Yuki
Majalah Anestesia & Critical Care Vol 43 No 1 (2025): Februari
Publisher : Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif (PERDATIN) / The Indonesian Society of Anesthesiology and Intensive Care (INSAIC)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55497/majanestcricar.v43i1.371

Abstract

Latar Belakang: Sepsis adalah disfungsi organ yang mengancam jiwa akibat respons tubuh yang tidak teratur terhadap infeksi. Kadar laktat serum sering digunakan sebagai biomarker kegagalan organ, di mana kadar yang lebih tinggi menunjukkan tingkat kerusakan yang lebih parah. Meskipun preloading cairan 20–30 cc/kgBB direkomendasikan dalam resusitasi sepsis pada periode one-hour bundle, efektivitas dosis yang berbeda masih belum jelas. Penelitian ini bertujuan menganalisis perbedaan dosis preloading cairan 20 cc/kgBB dan 30 cc/kgBB terhadap kadar laktat pada pasien sepsis di RSUP H. Adam Malik. Metode: Penelitian ini merupakan randomized clinical trial dengan metode double-blind, melibatkan 36 pasien sepsis yang dibagi menjadi dua kelompok yaitu kelompok 1 (20 cc/kgBB) dan kelompok 2 (30 cc/kgBB). Hasil: Tidak terdapat perbedaan bermakna dalam kadar laktat 6 jam setelah loading cairan (p>0,05). Namun, terdapat perbedaan signifikan pada nilai klirens laktat (p=0,002), di mana kelompok 1 (32,55 ± 30,69 mmol/L) memiliki klirens lebih tinggi dibandingkan kelompok 2 (15,62 ± 50,61 mmol/L). Simpulan: Preloading cairan 20 cc/kgBB setelah one-hour bundle meningkatkan nilai laktat klirens pada pasien sepsis.
Antibacterial Effect of Moringa oleifera Leaves on Staphylococcus aureus Based on Different Concentration and Harvest Time Panjaitan, Jeremia Aris; Kusumawati, R. Lia; Yunanda, Yuki; Lubis, Arvitamuriany Triyanthi
Biology, Medicine, & Natural Product Chemistry Vol 14, No 1 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.141.351-355

Abstract

This study investigates the antibacterial activity of Moringa oleifera leaf extract against Staphylococcus aureus ATCC 25923, focusing on the effects of harvest time and extract concentration. Leaves were harvested in the morning (08:00–10:00) and afternoon (15:00–17:00), then extracted with 96% ethanol. The antibacterial efficacy was evaluated using the Kirby-Bauer disc diffusion method at 60%, 70%, and 80%. The largest inhibition zone was observed at 80% concentration from the afternoon harvest (10.38 ± 0.43 mm), while the smallest was recorded at 60% from the morning harvest (8.25 ± 0.20 mm). Statistical analysis confirmed a significant concentration‑dependent antibacterial effect (p < 0.001, η² = 88.6%). However, harvest time did not significantly affect inhibition zone size (p = 0.882). These results suggest that M. oleifera is an effective natural antimicrobial agent against S. aureus, with concentration being the key determinant of antibacterial activity. Further research is recommended to explore its potential combined with antibiotics and its full therapeutic applicability.
Hubungan Antara Kelelahan dan Sindrom Burnout Pada Residen di Departemen Anestesiologi dan Terapi Intensif Venawati, Feni; Lubis, Andriamuri Prima; Bangun, Chrismas Gideon; Yunanda, Yuki
Jurnal Biomedika dan Kesehatan Vol 6 No 3 (2023)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2023.v6.330-339

Abstract

Background Anesthesiologists in Indonesia are still in high demand. The large number of patients and the heavy workload faced by residents are accompanied by quite high pressure from various aspects, this can cause anesthesia resident participants to experience fatigue so they are prone to a syndrome called burnout syndrome. This study aims to determine the relationship between fatigue and burnout syndrome among residents in the Anesthesiology and Intensive Therapy Department, Faculty of Medicine, Universitas Sumatera Utara. Methods This study was a cross-sectional study on 106 residents that was performed using a questionnaire consisting of characteristics of study samples, translated Fatigue Assessment Scale (FAS), and Maslach Burnout Inventory-Human Service Survey (MBI-HSS). Results From the analysis, it was discovered that 50% of the residents didn’t experience fatigue with a median score of FAS 21.5, and 84.9% of the residents didn’t experience burnout syndrome with a median score of MBI-HSS was 51,84 ± 19,59. There was a significant relationship between FAS and total score of MBI-HSS, emotional exhaustion, depersonalization, and personal achievement with p-value <0.001. Conclusions There was a significant relationship between FAS and total score of MBI-HSS, emotional exhaustion, depersonalization, and personal achievement.
Co-Authors Ahmad Ridho Lubis Alona, Ivana Andrio Farel Edward Gultom Arlinda Sari Wahyuni Bangun, Chrismas Gideon Bisono, Luwih Dadik Wahyu Wijaya Eka Setia Miharja Ester Lantika Ronauli Silaen Fujiati, Isti Ilmiati Hamdi, Tasrif Harahap, Juliandi Hendri Wijaya, Hendri Juliandi Harahap Kusumawati, R. Lia Lubis, Andriamuri Prima Lubis, Arvitamuriany Triyanthi Mhd Ihsan Panjaitan, Jeremia Aris Pohan, Alfindy Maulana Putri Chairani Eyanoer, Putri Chairani Qadri Fauzi Tanjung Ramud, Samawi Husein Rendi Sidiq Rina Amelia Rommy F. Nadeak Rommy F. Nadeak Rr Sinta Irina Tasrif Hamdi Venawati, Feni Wahyuni, Arlinda Sari