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All Journal Biospecies Jurnal Kesehatan Jurnal Riset Kimia JOURNAL OF HEALTHCARE TECHNOLOGY AND MEDICINE CHEMPUBLISH JOURNAL Sains Natural: Journal of Biology and Chemistry Jurnal Farmasi Higea Academy of Education Journal Jurnal Pengabdian Harapan Ibu (JPHI) Sainstek : Jurnal Sains dan Teknologi Khazanah Intelektual Riset Informasi Kesehatan Journal of Pharmaceutical and Sciences. Indonesian Journal of Chemical Engineering Indonesian Journal of Pharmaceutical Research
Lia Anggresani
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Engineering Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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STUDI ETNOFARFARMASI PADA SUKU ANAK DALAM (SAD) DI DESA PEMAYONGAN KECAMATAN SUMAY KABUPATEN TEBO PROVINSI JAMBI: STUDI ETNOFARFARMASI PADA SUKU ANAK DALAM (SAD) DI DESA PEMAYONGAN KECAMATAN SUMAY KABUPATEN TEBO PROVINSI JAMBI Perawati, Santi; Sutrisno, Deny; Ara Ofiana; Deny Sutrisno; Siti Hamidatul 'Aliyah; Lili Andriani; Rizky Yulion Putra; Rahmadevi; Desi Sagita; Yuni Andriani; Lia Anggresani; Barmi Hartesi
Jurnal Khazanah Intelektual Vol. 7 No. 2 (2023): Khazanah Intelektual
Publisher : Balitbangda Provinsi Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37250/khazanah.v7i2.198

Abstract

Background : Suku Anak Dalam is one of the tribes in Indonesia who still upholds their customs and culture, including their local knowledge about medicine using medicinal plants. One of the Suku Anak Dalam community lives in Pemayongan Village, Tebo Regency, Jambi Province. This ethnopharmaceutical research was conducted to find out various diseases experienced by Suku Anak Dalam and to know various natural resources that are used as treatment. Method : This type of research is a descriptive study using qualitative methods and sampling techniques, namely snowball sampling through open-ended interviews with informants. Results: The results of the study stated that diseases that was often experienced by the Suku Anak Dalam included fever, coughing, itching, shortness of breath and abdominal pain. Treatment of the disease by utilizing natural resources in the form of plants and animals. Plant parts used are roots, leaves, bark, and fruit sap, while for animals the parts used are fat, scales, and meat. The processing method is scraped, crushed, boiled, fried, while the use of these ingredients is eaten, drunk, and applied to the affected part. Conclusion : Based on the results of research that has been done there are 5 diseases that often occur and there are 9 kinds of plants and 5 animals that are used as traditional medicine. Keywords : Ethnopharmacy, Disease, Jambi, Suku Anak Dalam, Natural Resources
Utilizing Anadara granosa Shells and PVA for Porous Hydroxyapatite Synthesis Anggresani, Lia; Nurmelinda, Nurmelinda; Yulianis, Yulianis; Lee Wah Lim
Indonesian Journal of Chemical Engineering Vol. 1 No. 2 (2023)
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26555/ijce.v1i2.663

Abstract

The majority of the inorganic material that makes up teeth and bones is called hydroxyapatite (Ca10(PO4)6(OH)2), and it is produced by isolating calcium oxide (CaO) from the high calcium carbonate content of anadara granosa shells, which is over 98%. The porous HAp is the type of hydroxyapatite that can be used for bone repair. The aim of this work is to use the polymer polyvinyl alcohol to synthesis porous hydroxyapatite from anadara granosa shell. The anadara granosa powder (AGP) was furnaced for 3 hour at 800oC. CaO powder was produced. Then, the CaO powder was treated with (NH4)2HPO4 at a mol Ca/P 1.67 to obtained the HAp. Then, HAp is combined with a PVA polymer at a 10:1 ratio. Compressive strength tests, FTIR, SEM, and XRD are carried out. The compressive strength resulted for HAp and porous HAp were14.58 and 50.43 Mpa., respectively. The results indicated that PVA achieved a good compressive strength with Hydroxyapatite – Anadara granosa shell.
A Review: Analysis Atomic Absorption Spectrometry (AAS) of Heavy Metal Content in Crude Palm Oil Veranica; Rahayu, Aster; Maryudi; Lim , Lee Wah; Anggresani, Lia
Indonesian Journal of Chemical Engineering Vol. 2 No. 1 (2024)
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26555/ijce.v2i1.694

Abstract

Indonesia, the world's largest producer of crude palm oil (CPO), turns its oil through a series of refinement processes that include degumming, bleaching, and deodorization before it is used as cooking oil. Still, heavy metals are the main focus of CPO research. Elements known as heavy metals can have harmful effects on the human body, even in small doses. Making sure the amount of metal in CPO doesn't go over the limit is crucial. To find out how much this ingredient contributes to the heavy metal contamination in crude palm oil, more research is required. The CPO refining process is carried out with the aim of reducing free fatty acids and removing dirt or metals dissolved in CPO, which can affect the quality of cooking oil. AAS can detect metals in small amounts and provide analytical differences of up to 0.006 mg/kg.
Isotherm Adsorption of Ion Phosphate from Vinasse Waste Using Quaternary Ammonium Polymer as Adsorbent in Term Effect of Temperature Veranica; Rahayu, Aster; Maryudi; Dhias Cahya Hakika; Lee Wah Lim; Lia Anggresani
Sains Natural: Journal of Biology and Chemistry Vol. 14 No. 2 (2024): Sains Natural
Publisher : Universitas Nusa Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31938/jsn.v14i2.720

Abstract

Vinasse liquid waste is a waste product resulting from the ethanol distillation process. Phosphate in high concentrations can harm the environment, such as by polluting water sources and underground surfaces. In this research, adsorption of phosphate ions was carried out in vinasse waste to remove these pollutants using quaternary ammonium polymers. The study examined the effect of vinasse waste sample temperature on the adsorption of phosphate ions. The first step in this work was to create a quaternary ammonium polymer utilising a one-pot technique using 2-[methacryloyloxy)ethyl trimethylammonium chloride solution, also referred to as META. Subsequently, the adsorption process was performed using temperature variations of 25, 30, 40, 50, and 60 . Phosphate ion adsorbance was measured with UV-Vis spectrometers at a wavelength of 880 nm. The quaternary ammonium polymer succeeded in adsorbing the phosphate ion content of the vinasse waste at an optimal temperature of 40 , with an adsorption capacity of 3.78 mg/L and a removal efficiency of 75.70%.  The adsorption isotherm model for phosphate ions onto quaternary ammonium polymer was studied using the Freundlich and Langmuir equations. The obtained data indicated that the Langmuir isotherm model, with an value of 0.9921, is well-suited for describing the adsorption behaviour in this research.
Isothermic Adsorption Study of Nitrate Ion Adsorption in Bioethanol Waste Using Quaternary Ammonium Polymer Amrillah, Nafira Alfi Zaini; Rahayu, Aster; Dhias Cahya Hakika; Vivi Sisca; Veranica; Firda Mahira Alfiata Chusna; Lia Anggresani; Lee Wah Lim
Sains Natural: Journal of Biology and Chemistry Vol. 15 No. 1 (2025): Sains Natural
Publisher : Universitas Nusa Bangsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31938/jsn.v15i1.770

Abstract

The global shift towards renewable energy sources has led to a significant increase in bioethanol production, particularly from sugar mills. Despite being an environmentally friendly alternative to fossil fuels, bioethanol production produces large amounts of waste containing dangerous contaminants such as nitrate ions (NO₃⁻). These contaminants pose severe environmental and health risks, including water pollution and eutrophication. This study explores the use of ammonium polymer as an adsorbent and the influence of pH in the adsorption process as a promising technique for removing nitrate ions from bioethanol waste. Based on the analysis that has been carried out, the optimal pH for adsorption of nitrate ions is around 9, where the removal efficiency (%RE) reaches 98.43% and the adsorption capacity (Qe) is 24.86 mg/g. These experiments show that the Freundlich model, with a heterogeneity factor (n) of 1.0947 and a Freundlich constant (KF) of 1.92 x 10³ units, provides the best fit to the adsorption data, indicating a heterogeneous adsorption process with a strong affinity for nitrate ions.
Formulasi Gel dari Fraksi Etil Asetat Batang Jarak Cina (Jatropha multifida L.) Efektivitas Terhadap Luka Bakar Giovana Zola, Elpa; Hartesi, Barmi; Anggresani, Lia
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 3 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i3.966

Abstract

Background: Burns represent a condition of damaged or lost skin tissue due to high-temperature exposure. Oral therapy has limitations in penetrating hardened skin tissue, necessitating topical preparations such as gels that offer advantages in comfort, absorption capability, and ease of application. The stem of physic nut (Jatropha multifida L.) contains bioactive compounds including alkaloids, flavonoids, saponins, and tannins that may accelerate burn wound healing, particularly in its ethyl acetate fraction. Objective: This study aimed to formulate the ethyl acetate fraction of physic nut stem into a gel preparation and evaluate the effect of concentration variations on burn wound healing efficacy. Methods: Physic nut stems were extracted with 96% ethanol, then fractionated using n-hexane, ethyl acetate, and ethanol solvents. The ethyl acetate fraction was formulated into a hydrophilic gel at concentrations of 0.140%, 0.281%, and 0.421%. The gel preparations were evaluated through organoleptic tests, homogeneity, pH, spreadability, stability, irritation, and burn healing efficacy tests in rabbits. Results: Phytochemical screening revealed that the ethyl acetate fraction contained alkaloids, flavonoids, saponins, and tannins. All gel formulations met physical preparation requirements with skin-compatible pH (5.95-6.37). Formula F1 (0.140%) demonstrated optimal burn healing efficacy, equivalent to positive control (p > 0.05), and was topically safe (non-irritating). Conclusion: The ethyl acetate fraction of physic nut stem was successfully formulated into a stable and effective gel preparation for burn wound healing, with 0.140% as the optimal concentration. Further studies are required to examine toxicity and the mechanism of action of active compounds.
Ethnopharmacy Study of Suku Anak Dalam (SAD) in Muara Kilis Village, Tengah Ilir, Tebo District, Jambi Province Perawati, Santi; Andriani, Lili; Anggresani, Lia; Ardila, Eti
Biospecies Vol. 12 No. 2 (2019): Juli 2019
Publisher : Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (156.254 KB) | DOI: 10.22437/biospecies.v12i2.5551

Abstract

ABSTRACT Background: Indonesia consists of various ethnics on each island, one of which is Suku Anak Dalam (SAD) precisely on Sumatra island of Jambi Province. Each ethnic group has a variety of natural and traditional remedies. This observation was conducted from November 2017 to February 2018 in Muara Kilis Village, Tengah Ilir District, Tebo District, Jambi Province.This research purpose to determined of various disease and know the various natural resources that are used as a treatmenton Suku Anak Dalam at Muara Kilis. Method: This research type is descriptive research using qualitative method and purposive sampling for sampling technique and open-ended interview with informant using voice recording media. Results: The disease are often experienced by Suku Anak Dalam among others fever, cough, asthma, measles, gastritis, hemorrhoids, stomachaches, and allergy. To treat the disease by utilizing natural resources like plants and animals. Part of the plants used among others, leaves, sap, and fruit, while for animal parts used are bile, urine, and blood. Processing methods are pounded, boiled, grated, and fried, while the use of these ingredients by eating, drinking, bathed, and applied directly on part of sickness skin Conclusion: Based on the results that has been done there are 8 diseases that often occur and there are 5 kinds of plants and 4 animals from different genus and family that are used as traditional medicine in Suku Anak Dalam Muara Kilis Village. Keywords: (Ethnopharmacy, Suku Anak Dalam, Diseases, Natural Resources)
Impact of magnetite on Fe3O4/Activated Carbon (AC)/ZnO Nanocomposite for Photodegradation of Rhodamine B Bemis, Restina; Marlinda, Lenny; Rahmi; Pratiwi, Nurul; Wibimanyu, Putu Adityo; Lia Anggresani
Chempublish Journal Vol. 9 No. 2 (2025): Chempublish Journal (July - December)
Publisher : Department of Chemistry, Faculty of Science and Technology Universitas Jambi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/chp.v9i2.47812

Abstract

Rhodamine B is an organic dye commonly used in the textile industry, but it is toxic. Therefore, a photodegradation method using Fe3O4/activated carbon (AC)/ZnO nanocomposite is necessary to address environmental issues caused by rhodamine B. The Fe3O4/AC/ZnO nanocomposite has been successfully synthesized using the sonication method. Iron sand is used as a source of magnetite (Fe3O4), coconut shells as a source of activated carbon, and Zinc nitrate as a source of ZnO. XRF results show that the Fe content in iron sand is 74.10%. The ratio of Fe3O4 addition used in Fe3O4/AC/ZnO nanocomposite is 0:1:1; 1:1:1; 2:1:1; 3:1:1; 4:1:1. XRD characterization shows that the 1:1:1 ratio of Fe3O4/AC/ZnO nanocomposite has the smallest crystal size of 48.17 nm. The addition ratio of Fe3O4 does not affect the structure of the formed Fe3O4/AC/ZnO nanocomposite. Fe3O4/AC/ZnO nanocomposite is formed at 2theta 30.23°; 35.60°; 57.11°; and 62.83° for Fe3O4, peak broadening at 26.72° and ~44.71 for AC, and 31.82°; 34.47°; 36.30°; 47.59°; 56.63°; 62.89° and 67.98° for ZnO. SEM results show particle sizes of 57.95 nm for ZnO and 42.74 nm for Fe3O4/AC/ZnO 1:1:1 nanocomposite. VSM showed saturation magnetism of 4.41 emu/g for Fe3O4/AC/ZnO 1:1:1 nanocomposite and 28.8 emu/g for Fe3O4. The photocatalytic test showed that the Fe3O4/AC/ZnO 1:1:1 nanocomposite had the best % degradation of rhodamine B, at 96.1%, under sunlight.
Pengaruh Paparan Radikal Bebas terhadap Kerusakan DNA dan Aktivasi Mekanisme Perbaikan DNA pada Sel Epitel Untary, Dwi Marlen; Chairunisa, Ully; Anggresani, Lia; Alifa, Aurora
Indonesian Journal of Pharmaceutical Research Vol 5, No 2 (2025): Indo J Pharm Res 2025 5 (2)
Publisher : Department of Pharmacy, Muhammmadiyah University of Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31869/ijpr.v5i2.7737

Abstract

Paparan radikal bebas dikenal dapat menyebabkan kerusakan pada DNA dan mengaktifkan mekanisme perbaikan sel, khususnya pada sel epitel yang sering kali terpapar stresoksidatif dari lingkungan. Penelitian ini bertujuan untuk menilai dampak dari paparan hidrogen peroksida (H₂O₂) terhadap kerusakan DNA dan aktivasi jalur perbaikan DNA dalam sel epitel manusia (HaCaT). Desain dari penelitian ini adalah studi eksperimental in vitro yang melibatkan lima kelompok perlakuan H₂O₂ (0–400 µM). Metode pengukuran yang digunakan mencakup viabilitas sel (MTT), produksi ROS intraseluler (DCFH-DA), tingkat kerusakan DNA (Comet assay, 8-oxo-dG ELISA, dan γ-H2AX), serta ekspresi gen/protein perbaikan DNA (OGG1, APE1, ATM, dan TP53) yang diukur melalui qPCR dan Western blot. Hasil menunjukkan bahwa paparan H₂O₂ menurunkan viabilitas sel secara signifikan pada konsentrasi ≥100 µM (p 0.05) dan meningkatkan produksi ROS secara dosis-respons hingga 7,2 kali lipat poada 400 µM. Kerusakan DNA meningkat seiring peningkatan dosis, ditunjukkan oleh kenaikan tail moment Comet assay (2,1 menjadi 65,0), peningkatan kadar 8-oxo-dG (0,35 menjadi 4,90 ng/mL), serta jumlah γ-H2AX foci per inti (0,8 menjadi 20,5). Ekspresi gen OGG1, APE1, dan ATM meningkat pada dosis rendah–sedang (50–200 µM), sedangkan aktivasi TP53 meningkat tajam pada 400 µM, menunjukkan kecenderungan menuju apoptosis atau penghentian siklus sel. Secara keseluruhan, penelitian ini mengindikasikan bahwa paparan radikal bebas menimbulkan kerusakan DNA yang signifikan dan memicu respons perbaikan DNA, namun pada tingkat paparan tinggi kapasitas perbaikan sel menurun dan jalur stress response p53 menjadi dominan. Temuan ini menegaskan pentingnya keseimbangan antara paparan oksidatif dan kapasitas perbaikan DNA dalam menjaga stabilitas genom sel epitel.Kata kunci: radikal bebas, ROS, sel epitel, perbaikan DNA, BER, γ-H2AX.
Co-Authors Ahmad Sukron Alifa, Aurora Amrillah, Nafira Alfi Zaini Ara Ofiana Ardila, Eti armini hadriyati, armini Astridawati, Indah Ayar Muhammad Adlu Barmi Hartesi Chairunisa, Ully Desi Sagita Dhias Cahya Hakika Firda Mahira Alfiata Chusna Fitri Diana Giovana Zola, Elpa Haflin Haflin Haflin, Haflin HARTESI, HARTESI Lee Wah Lim Lenny Marlinda Lili Andriani Lim , Lee Wah Lusyana, Indah Mahadma Bhima Whinata Mar’ie, Hibatullah Maryudi Medina, Fhatia Melianti, Dita Muammar Khadafi Novesar Jamarun Nurmelinda, Nurmelinda Nurul Pratiwi Rahayu, Aster Rahmadevi Rahmi Randa, Muhammad Restina Bemis, Restina Risnawati, Ida Rizky Yulion Santi Perawat Santi Perawati Santi Perawati, Santi Perawati, Santi Sari, Julia Ambar Siti Hamidatul 'Aliyah Supriadi Supriadi Suryani Suryani Sutrisno , Deny Swinche, Ulfa Deni Syukri Arief Untary, Dwi Marlen Veranica Vivi Sisca Whinata, Mahadma Bhima Wibimanyu, Putu Adityo Yanti, Novebri Yuliana, Mona Yulianis Yulianis Yuni Andriani Zuama, Novena