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All Journal Indonesian Journal of Pharmaceutical Science and Technology IDJP (Indonesian Journal of Pharmaceutics) Journal of Pharmacopolium JSFK (Jurnal Sains Farmasi & Klinis) PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Borneo Journal Of Pharmascientech Current Research on Biosciences and Biotechnology Edu Masda Journal Jurnal Abdimas Kartika Wijayakusuma Jurnal Sains dan Teknologi Farmasi Indonesia Jurnal Farmasi Indonesia Pharmaceutical Science Journal
Yola Desnera Putri
Sekolah Tinggi Farmasi Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : Pharmaceutical Science Journal

 1 
FORMULASI DAN EVALUASI KRIM KEFIR SUSU KAMBING DENGAN PENAMBAHAN EKSTRAK KULIT BUAH NAGA MERAH (Hylocereus polyrhizus [F.A.C Weber] Britton & Rose) SEBAGAI ANTIOKSIDAN Yola Desnera Putri
PHRASE (Pharmaceutical Science) Journal Vol 2, No 1 (2022): PHRASE (PHARMACEUTICAL SCIENCE) JOURNAL VOL 2 NO 1 (2022)
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v2i1.238

Abstract

Kefir yang dikombinasi ekstrak kulit buah naga merah (Hylocereus polyrhizus) mempunyai banyak manfaat, selain antioksidan yang kuat namun mempunyai manfaat lain yaitu sebagai bahan pencerah alami, melembabkan kulit serta dapat membuat kulit terlihat awet muda. Tujuan dari penelitian ini adalah untuk menguji sediaan krim kefir ekstrak kulit buah naga merah yang memiliki aktivitas antioksidan. Pengujian aktivitas antioksidan di lakukan dengan metode DPPH. Kefir dan ekstrak di formulasikan dalam bentuk sediaan krim dengan tiga perbandingan basis asam stearat dan trietanolamin (16,7:2,3), (15,7:3,3) dan (14,7:4,3) gram, hasil penelitian menunjukkan bahwa kombinasi 16,7:2,3 gram  merupakan basis yang paling baik maka di buat formula tiga konsentrasi yang berbeda 1% (F1), 2% (F2) dan 4% (F3). Evaluasi sediaan krim meliputi uji organoleptik, uji homogenitas, uji pH, uji viskositas, uji daya sebar, uji iritasi dan uji sentrifugasi yang memenuhi persyaratan. Hasil penelitian menunjukkan antioksidan krim pada hari ke-0 dengan nilai IC50 F1, F2 dan F3 adalah 159, 142, dan 72,81 ppm. Setelah penyimpanan selama 28 hari nilai IC50 F1, F2, dan F3 menjadi 187, 148 dan 75,31 ppm.
FORMULASI DAN EVALUASI SABUN PADAT DENGAN PENAMBAHAN YOGHURT SEBAGAI ANTIOKSIDAN Yola Desnera Putri; Ledianasari Ledianasari; Giani Nurrahmawati
PHRASE (Pharmaceutical Science) Journal Vol 3, No 1 (2023): Pharmaceutical Science Journal Vol 3 No 1, 2023
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v3i1.518

Abstract

Soap was used to clean the skin but not damage the skin and able to protect skin from free radical effect. The compounds that could counteract free radical are antioxidants which can be found in yoghurt. The purpose of this research was to determine the formula and evaluation of solid soap with the addition of yoghurt according to the SNI 2016 requirements. The methods used are making yoghurt, evaluating yoghurt, testing the antioxidant activity of yoghurt, formulating solid soap, and evaluating solid soap. Solid soaps F1, F2, F3, F4 with yoghurt concentrations were 2; 2.5; 3; 3.5. The evaluation results of solid soaps from yoghurt to the four formulas had good results, namely water content, insoluble material in ethanol, free fatty acids, and chloride levels that met the SNI 2016 requirements. The evaluation of the antioxidant activity test showed that the yoghurt was 57.87 µg / mL with the category strong and of the four solid soap formulas only F1 and F4 still have strong antioxidant activity. F1 with antioxidant activity of 98.81 µg / mL in the strong category, and F4 with antioxidant activity of 82.36 µg / mL in the strong category.
FORMULASI SEDIAAN MIKROEMULSI TRANSDERMAL PIROKSIKAM DENGAN MENGGUNAKAN VIRGIN COCONUT OIL (VCO) SEBAGAI FASE MINYAK Yola Desnera Putri; Haruman Kartamihadrja; Lusi Fauziah
PHRASE (Pharmaceutical Science) Journal Vol 2, No 2 (2022): PHRASE (PHARMACEUTICAL SCIENCE) JOURNAL VOL 2 NO 2 (2022)
Publisher : Sekolah Tinggi Ilmu Kesehatan Widya Dharma Husada Tangerang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52031/phrase.v2i2.399

Abstract

Piroxicam is a non-steroidal anti-inflammatory drug thus in the oral dosage of piroxicam often can irritate the stomach, thus piroxicam was made be of a transdermal microemulsion  preparation. The research was conducted in the preparation of transdermal piroxicam microemulsions by used Virgin Coconut Oil (VCO) as oil phase and tween 80 as a surfactant. The formula was varied into 5 formulas with distinguished tween 80 concentrations of 40%, 45%, 50%, 55%, 60% and propylene glycol as cosurfactants with 15% concentration, and emulsion preparations without the addition of propylene glycol as cosurfactants. This study aimsed to created a stable and transparent physically microemulsion preparation and determined piroxicam the ratio of diffusion rate in piroxicam microemulsions and  piroxicam emulsions. The test was performed by using Franz diffusion test by using Whatman membrane. In the microemulsion formula, the percentage of diffused piroxicam content obtained was greatest at F5 (24.35%) at 180 minutes and compared to emulsion (2,66%). The diffusion test resultsed show that the effect of addition of cosurfactant at the diffusion rate of the microemulsion preparation is compared to the emulsion preparation without the addition of cosurfactant. This cosurfactant can help surfactants to penetrate skin membranes.
Co-Authors Alhamd, Mutiara Aneu Nurdiana Angga Julianto Anisa D. Aryanti Anisa D. Aryanti, Anisa D. Ayuningtyas, Yudyana Aziza, Farradiba Nur Brilian, Alifa Deby - Tristiyanti Deby Tristiyanti Dytha Andri Deswati, Dytha Andri Ferdiansyah, Rival Fitriani, Dewi Fatimah Giani Nurrahmawati Gustini, Sri Hamdani, Syarif Haruman Kartamihadrja Haruman Kartamihardja Holis Abdul Holik Holis Abdul Holik, Holis Abdul Ida Musfiroh Ida Musfiroh, Ida Intan Lisna Julianto, Angga K Sari, Nia Ledianasari Ledianasari Ledianasari, Ledianasari Ledianasari, Ledianasari Legowo, Wahyu Priyo Lusi Fauziah Mardiah, Irma Marianta - Teresia Meisy Afdina Muhammad Haris Novitaria Br Sembiring Nur Asni Setiani P Legowo, Wahyu Riski Nur Utami Sani Nurlaela Fitriansyah Sohadi Warya Sohadi Warya Sriwidodo Sriwidodo, Sriwidodo Tristiyanti, Deby