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Sabrina Hayati
Universitas Abdurrab
Agriculture, Biological Sciences & Forestry Arts Humanities Computer Science & IT Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

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Lunasin's Mechanism as an Antioxidant and Hypocholesterolemic Agent Santi Widiasari; Sabrina Hayati; May Valzon; Wahyu Ramadhan
International Journal Of Health Science Vol. 5 No. 1 (2025): : International Journal of Health
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/ijhs.v5i1.5637

Abstract

Several ways that can help lower cholesterol levels in the blood include using drugs (pharmacotherapy) or by modifying lifestyle and consuming certain foods. One of them is lunasin. Lunasin is a peptide found in soybean plants and is a promising drug candidate because it has broad health effects such as antioxidant, anti-inflammatory, anti-cancer, and lowering blood cholesterol through various mechanisms. This paper aims to examine the role and mechanism of action of lunasin as an antioxidant and its ability to lower blood cholesterol levels due to the unique peptide structure of lunasin as well as the bioavailability of lunasin starting from degradation, absorption, translocation and distribution of lunasin to target organs or target tissues after oral administration . This paper also discusses soybean plants as the main source of lunasin and the optimal content of lunasin in soybeans.
Co-Authors Abdul Karim Abdul Karim Adam Adam Afriwardi Afriwardi Akbar, Alifya Aldama, Ardita Alfatlillah Alhafisht Amdila, Reyhan Amelia, Cici Arnila Melina Attachira Br. Ritonga Cheesa Prisilla Ronald Dela Agung Septriady Egis Feby Asyaroh Elanesi Esvandhiary, Faradilla Eva Oktariani Evy Eryta Fahmi Novriandi Faroliu, Goldha Inggrit Anggraini Jayu, Prastiwi Julianis, Erva Lisa Sari, Lilis M. Naufal Makarim Misfa, Olvaria Muhammad Arief Mustaqim Mursyida, Eliya Nadya Putri Auliya Nengsi Fitria Neni Ristiani Novita Rahman, Fauzya Nurmaliza, Nurmaliza Oriza Sativa Pratiwi, Yuharika Putri Wulandini Rahayu, Yessi Ramadhan, Kurnia Riki Richer Ruswaldi Munir Safitri, Bellanera Alifia Samosir, Nova Relida Santi Widiasari Santi Widiasari, Santi SAPUTRA, DEBI Sativa, Oriza Siska Andriani Rukmana Siska Silviana Siti Nurbaiti Stephen Scorpianus Ryanto Supriadi Supriadi Tasya Rani, Diana Valzon, May Veni Dwi Lestari Wahyu Margi Sidoretno Wahyu Ramadhan Wahyu Ramadhan Windy Claudya Yan Hendrika Zulfan Rasyidi