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All Journal Shaut Al-'Arabiyah Jurnal Psikologi Teori dan Terapan Jurnal Pengabdian Hukum Indonesia (Indonesian Journal of Legal Community Engagement) JPHI Insight: Jurnal Ilmiah Psikologi Jurnal Suara Keadilan Media Iuris Psikosains: Jurnal Penelitian dan Pemikiran Psikologi Amsir Law Jurnal (ALJ) PENGABDI: Jurnal Hasil Pengabdian Masyarakat Indonesian Journal of Community Dedication in Health (IJCDH) Hang Tuah Medical Journal Room of Civil Society Development Gema Lingkungan Kesehatan Jurnal Pengabdian Nasional (JPN) Indonesia Wulang: Jurnal Pendidikan Guru Madarasah Ibtidaiyah Room of Civil Social Development Iftitiah: Jurnal Ilmiah Pendidikan Islam Anak Usia Dini PALASTREN: Jurnal Studi Gender
Fatimatuz Zahra, Fatimatuz
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Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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Efek Sinergis Vitamin C Dalam Meningkatkan Kinerja Antijamur Madu Apis dorsata Terhadap Biofilm Candida albicans Untuk Terapi Kandidiasis MASFUFATUN; ZAHRA, FATIMATUZ; AGUSTIN ANGRAENI, DWI PUTRI; NUZULA, FIRDAUSI
Hang Tuah Medical Journal Vol 22 No 1 (2024): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v22i1.698

Abstract

Honey is a natural ingredient produced by bees from flower nectar that has antimicrobial, antioxidant, anti-inflammatory, good wound healing effects, and bacteriostatic. This study aims to determine the synergistic effect of vitamin C in improving the antifungal performance of Apis dorsata honey against Candida albicans biofilm for candidiasis therapy. This research design is true experimental with a post-test only control group design approach using the microtiter plate assay method to measure the Optical Density (OD) value of the biofilm matrix. The test of the synergistic effect of Vitamin C on Honey was carried out by adding vitamin C to honey concentrations of 5%, 10%, 15%, 20%, 25%, 30%, 35%, 40%, 45%, and 50%. Furthermore, the MBIC50 value between honey and the combination of honey and vitamin C was compared. The results showed that both honey and the combination of honey and vitamin C were each able to decrease the growth of C. albicans biofilm matrix against A. dorsata honey at various concentrations. The results of the Minimum Biofilm Inhibitory Concentration 50% (MBIC50) value in A. dorsata honey and the combination of A. dorsata honey and vitamin C were 84.27% and 63.56% respectively. Based on this study, it can be concluded that vitamin C can increase the antifungal performance of A. dorsata by lowering the MBIC50 value. Thus, the combination of vitamin C and honey can be used as an alternative therapy for candidiasis.
Co-Authors Agusniar Furkani Listyawati AGUSTIN ANGRAENI, DWI PUTRI Ahdan, Fatmaziza Berliane Alfajri, Muhamad Alaihun Amelasasih, Prianggi Aryani, Lia Duwi Aspar MS, Rezky Fathiyah Putri Dakum, Dakum Dody Rahayu Prasetyo, Dody Rahayu Elmuna, Nilna Febiana, Novi Febriantie, Eka Ladya Charyl Firdausi Nuzula Firman Menne Ima Fitri Sholichah Laili, Fadzila Nur Maali, Abul Machfiroh, Ade Safriani Maimunah, Nurul Ayatul Masfufatun Moh. Jufriyanto Nabila, Sherly Helma Nadhirotul Laily Nasrullah, Muhammad Pazri Ningsih, Fahriya Norazizah, Siti Nurmuhamad, Fendy Pratama, Gito Aji Primanthoro, Ramdhan Purwasetiawatik, Titin F. Putri, Sunita Rahayu Rabbani, Nazwa Nayya Nanita Rahayu Puji Lestari Rifky, Haidar Riyadi, Dedek Muhammad Rohmah, Siti Mufidhatur Sabila, Yuffa Maulana Safitri, Eli Sarniwatie Sofii, Abdul Johan Suci Muzfirah Suparnyo Surya, Faizal Adi Thalib, Tarmizi Tsurayya, Husna Uzlifatul Jannah