Teguh Prakosa, Teguh
Faculty Of Medicine, Universita Sebelas Maret / Department Of Obstetrics And Gynecology, Dr. Moewardi Hospital, Ir. Sutami 36 A, Kentingan Surakarta 57126 Telp. (0271) 662622

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Analysis of the COVID-19 Severity Based on NLR and the Mortality Rate of Pregnant Women with COVID-19 at Dr. Moewardi General Hospital, Surakarta, Central Java, Indonesia Rachma, Dhea Fitria; Prakosa, Teguh; Setyawan, Sigit; Laqif, Abdurahman
Indonesian Journal of Medicine Vol. 7 No. 4 (2022)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (31.196 KB) | DOI: 10.26911/theijmed.2022.7.4.592

Abstract

Background: Coronavirus Disease 2019 (COVID-19) is a disease of the human respiratory system. Pregnant women are more susceptible to respiratory infections due to physiological changes in the immune and cardiopulmonary systems. Routine laboratory biomarkers such as lymphocytes, neutrophils, and NLR are considered prognostic in COVID-19. This study aimed to analyzed the severity of COVID-19 based on NLR on the mortality of pregnant women with COVID-19 at Dr. Moewardi, Surakarta.Subjects and Method: This study used analytic observational with a cross-sectional. The study subjects were 82 pregnant women with confirmed COVID-19, aged over 18 years, and being treated at RSUD Dr. Moewardi Surakarta between March 2020 to January 2022. The samples were taken using the consecutive sampling technique. The independent variable is the severity of COVID-19 based on clinical presentation. The dependent variable is the laboratory results in lymphocytes, neutrophils, and NLR. Data were collected from medical records and anlayzed using SPSS software.Results: There was correlation between NLR on the severity of pregnant women with COVID-19 (Mean= 10.11; SD= 4.10; p= 0.026) and there was a significant correlation between NLR on the mortality rate of pregnant women with COVID-19 (Mean= 9.92; SD= 3.94; p<0.001).Conclusion: NLR affected the severity and the mortality rate among pregnant women with COVID-19.Keywords: COVID-19, pregnancy, lymphocytes, neutrophils, NLR, mortalityCorrespondence: Dhea Fitria Rachma. Faculty of Medicine Universitas Sebelas Maret Surakarta. Jl. Ir. Sutami 36A, Surakarta 57126, Indonesia. Email: dheaf1020@student.uns.ac.id. Mobile: 085702594898.Indonesian Journal of Medicine (2022), 07(04): 401-410https://doi.org/10.26911/theijmed.2022.07.04.05 
Hubungan Kadar D-dimer pada Ibu Hamil COVID-19 terhadap Kejadian Intrauterine Fetal Death (IUFD) di RSUD Dr. Moewardi Sania Ainin Nuzula; Prakosa, Teguh; Setyawan, Sigit; Abdurahman Laqif
Plexus Medical Journal Vol. 3 No. 1 (2024): Februari
Publisher : Fakultas Kedokteran, Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/plexus.v3i1.1094

Abstract

Pendahuluan: Pada kehamilan umumnya terdapat peningkatan aktivitas koagulasi secara fisiologis. Tingkat keparahan COVID-19 juga sejalan dengan aktivasi jalur koagulasi. Salah satu parameter koagulasi adalah D-dimer. Peningkatan kadar D-dimer pada ibu hamil COVID-19  berhubungan dengan terjadinya hiperkoagulabilitas. Perubahan koagulasi tersebut dapat berisiko terhadap kejadian Intrauterine Fetal Death (IUFD) karena terganggunya supply nutrisi dan oksigen dari ibu ke janin. Penelitian ini bertujuan untuk mengetahui apakah terdapat hubungan antara kadar D-dimer pada ibu hamil COVID-19 dengan kejadian Intrauterine Fetal Death (IUFD) di RSUD dr. Moewardi. Metode: Penelitian ini dilaksanakan di RSUD dr. Moewardi dengan menggunakan pendekatan cross-sectional. Jumlah sampel yang diperlukan adalah 67 sampel yang terdapat dalam rekam medis sejak Maret 2020 sampai Maret 2023. Analisis data menggunakan SPSS dengan uji Chi Square.  Hasil: Hasil analisis bivariat pada 67 sampel ibu hamil COVID-19 yang terdiri dari 41 ibu hamil non IUFD dan 26 ibu hamil IUFD dengan menggunakan Chi Square didapatkan P-value sebesar 0,000 (P<0,05) dengan nilai Odds-Ratio 15,111. Kesimpulan: Terdapat hubungan antara kadar D-dimer pada ibu hamil COVID-19 terhadap kejadian Intrauterine Fetal Death (IUFD).  
Education on Assisted Reproductive Technology Program with Low Cost Budihastuti, Uki Retno; Laqif, Abdurahman; Melinawati, Eriana; Prakosa, Teguh; Udiyanto, Hermawan; Priyanto, Heru; ., Darto; Ratnasari, Affi Angelia; Anggraeni, Asih; Wijayanti, Agung Sari
Placentum: Jurnal Ilmiah Kesehatan dan Aplikasinya Vol 11, No 1 (2023): February
Publisher : Program Studi Kebidanan Fakultas Kedokteran Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/placentum.v11i1.64796

Abstract

Background: Assisted reproductive technology (ART) programs have proven to be a solution to help infertility couples to conceive. However, most couples face a financial crisis related to the relatively expensive cost of ART treatment. This service aims to educate about ART's meaning, direction, and procedures. Thus, couples want children to be able to understand the ART program at an affordable cost (low-cost) and undergo the ART program without any concerns about costs.Method: Seminar participants be given socialization in person and online through zoom software by the service provider. It is in two stages, in-person and online, so participants who cannot attend in person can follow this service program. In addition, participants are given a pre-test and post-test questions to assess their understanding of the ART program at an affordable cost.Result: The pre-test and post-test results were analyzed using Wilcoxon, which showed that after providing education about the ART program, the post-test results were significantly better than the pre-test results. Down value: 5.5%, fixed value: 15.2%, value rise: 79.3% with significance p<0.001.Conclusion: There are significant differences in the pre-test and post-test scores, which means that the participants understood the explanation the servicer gave.
Efforts to Increase Understanding of COVID-19 Screening in Assisted Reproductive Technology Services Budihastuti, Uki Retno; Laqif, Abdurahman; Melinawati, Eriana; Prakosa, Teguh; Udiyanto, Hermawan; Priyanto, Heru; ., Darto; Ratnasari, Affi Angelia; Anggraeni, Asih
Placentum: Jurnal Ilmiah Kesehatan dan Aplikasinya Vol 11, No 2 (2023): August
Publisher : Program Studi Kebidanan Fakultas Kedokteran Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/placentum.v11i2.74618

Abstract

Background: The assisted reproductive technology (ART) program for examining infertile couples requires face-to-face with a doctor. This face-to-face examination for the ART program has a risk for the transmission of COVID-19 to all medical personnel and infertile couples who want to undergo the ART program. This study aims to understand pre- and post-test education about COVID-19 screening on ART services.Methods: A total of 50 infertile couples in the ART program are given education online. The use of online methods using the Zoom application due to the COVID-19 pandemic. Evaluation of the level of understanding using pre and post-test providing education. Data analysis was carried out using the SPSS 23 application.Results: Analysis of the level of understanding of pre-test and post-test education using the Wilcoxon test. Pre-test results were 69.90±12.05, post-test 73.00±10.83 with significance values p<0.001. Chi-Square test analysis results obtained p<0.001 and OR = 15.68.Conclusion: There was a significant increase in understanding of COVID-19 screening in the post-test education ART service via the Zoom application compared to pre-test education.
Hubungan Endometriosis dengan Kejadian Infertilitas Wanita di Poliklinik Obstetri dan Ginekologi RSUD Dr. Moewardi Dihade, Ajeng; Hermawan Udiyanto; Teguh Prakosa
Plexus Medical Journal Vol. 5 No. 1 (2026): Februari
Publisher : Fakultas Kedokteran, Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/plexus.v5i1.2555

Abstract

Pendahuluan: Endometriosis merupakan penyakit sistemik kompleks di mana jaringan mirip endometrium tumbuh di luar rahim dan dapat mengganggu fungsi reproduksi. Salah satu komplikasi yang sering dikaitkan adalah infertilitas. Infertilitas memengaruhi sekitar 110 juta wanita di dunia dan meningkat sebesar 0,68% per tahun. Penelitian ini bertujuan mengetahui hubungan antara endometriosis dan infertilitas pada pasien di RSUD Dr. Moewardi. Metode: Penelitian observasional analitik dengan desain cross-sectional ini dilakukan pada 17–19 Juni 2025. Subjek adalah wanita usia reproduktif (20–45 tahun) yang telah menikah, terdiagnosis endometriosis melalui histopatologi, dan memiliki rekam medis lengkap. Sampel diambil secara purposive sampling sebanyak 50 pasien. Analisis data menggunakan uji chi-square dan perhitungan odds ratio. Hasil: Sebanyak 20 pasien (40%) terdiagnosis endometriosis dan 30 pasien (60%) tidak. Terdapat 30 pasien (60%) mengalami infertilitas dan 20 pasien (40%) tidak. Uji chi-square menunjukkan tidak ada hubungan signifikan antara endometriosis dan infertilitas (p = 0,077; OR = 3,00; CI 95%: 0,869–10,363). Analisis karakteristik menunjukkan usia memiliki perbedaan signifikan yang mungkin menjadi faktor perancu Kesimpulan: Tidak ditemukan hubungan yang signifikan secara statistik antara endometriosis dan infertilitas di RSUD Dr. Moewardi. Namun secara klinis, terdapat kecenderungan pasien dengan endometriosis memiliki risiko tiga kali lebih besar mengalami infertilitas dibandingkan pasien tanpa endometriosis.