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All Journal Martabe : Jurnal Pengabdian Kepada Masyarakat Jambura Journal of Chemistry Jurnal Mandala Pharmacon Indonesia Journal Syifa Sciences and Clinical Research (JSSCR) Indonesian Journal of Pharmaceutical Education Jurnal Kolaboratif Sains Jurnal Pengabdian Masyarakat Farmasi : Pharmacare Society Jurnal Kesehatan Farmasi Journal of Pharmaceutical and Sciences. Jurnal Farmasi Teknologi Sediaan dan Kosmetika (JFTSK) Journal of Pharmacology and Natural Products
Papeo, Dizky Ramadani Putri
Universitas Negeri Gorontalo
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Journal : Indonesian Journal of Pharmaceutical Education

 1 
Gambaran Penggunaan Obat Off-Label Pada Pasien Pediatrik Rawat Inap di Rumah Sakit Teti Sutriati Tuloli; Nur Rasdianah; Andi Makkulawu; Dizky Ramadani Putri Papeo; Maimun Datau
Indonesian Journal of Pharmaceutical Education Vol 2, No 2 (2022): Mei-Agustus 2022
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v2i2.11449

Abstract

Off-label drugs can be interpreted as drugs that are used not in accordance with drug information, distribution permits and sales licenses from the Marketing Authorization (MA) related to indications, age, dosage, route of administration and contraindications. The use of off-label drugs in children occurs because of incomplete data on pharmacokinetics, pharmacodynamics and side effect of a drug. It is because clinical research in children is quite difficult and not in accordance with research ethics and morals, so it has the potential to cause errors in treatment and unwanted drug reactions. This study aims to describe the use of off-label drugs in hospitalized pediatric patients at RSUD of Dr. M.M Dunda Limboto, Gorontalo District, Gorontalo Province. This is an  observational study using cross sectional design and retrospective data collection. The sampling technique applies a purposive sampling technique with a total of 155 patients who meet the inclusion criteria during the January-June 2020 period. The finding shows that from 155 patient medical records, there are 172 (16,51%) off-label drug used with a total of 1042 drugs. The off-label drugs used in the indication category are 64,53%, the off-label drugs used in dose category are 17,44%, the off-label drugs used in age category are 14,53%, the off-label drugs used in route of administration category are 3,49% and the off-label drugs used in contraindications category are not found. The are the most off-label drugs used in each category, including domperidone (off-label in indications and dose), rhinofed (off-label in age) and salbutamol (off-label in route of administration).
Pengaruh Variasi Konsentrasi Ekstrak Buah Mahkota Dewa (Phaleria macrocarpa) Terhadap Stabilitas Fisik Sediaan Krim Nur Ain Thomas; Robert Tungadi; Dizky Ramadani Putri Papeo; Andi Makkulawu; Yuni Sarah Manoppo
Indonesian Journal of Pharmaceutical Education Vol 2, No 2 (2022): Mei-Agustus 2022
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v2i2.13532

Abstract

God's crown is one of the plants with various components with flavonoid as one of these components, which is an abundant plant metabolite component in nature that significantly functions for the plant's growth and antioxidants. This study aimed to examine The Concentration Variation Effect of 70% Ethanol Extract from God's Crown (Phaleria Macrocarpa) Towards The Physical Stability of Cream Preparations by variating the extract concentration. The formula concentration on the extract consists of FI (1%), FII (3%), FIII (5%), by stearic acid, paraffin liquid, alcohol cetyl, paraben propyl for the oil phase, aquadest, triethanolamine (TEA), and methylparaben for the water phase. Further evaluations include organoleptic test (smell, color, texture), pH test, homogeneity test, viscosity test, distribution test, and adhesion test. Each evaluation result found changes as intended by the research purpose, which is the effect of the extract's concentration variation on the physical stability of the cream preparations.
Hubungan Antara Kepatuhan Minum Obat (MMAS-8) Dan Kualitas Hidup (WHOQOL-BREF) Penderita Tuberkulosis Di Puskesmas Di Kota Bandung Papeo, Dizky Ramadani Putri; Immaculata, Maria; Rukmawati, Iis
Indonesian Journal of Pharmaceutical Education Vol 1, No 2 (2021): Mei-Agustus 2021
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v1i2.11143

Abstract

Backgroumd: Tuberculosis (TB) is an infectious disease which is until now has not been able to be threated, i.e., because of patient non-adherence in taking anti-tuberculosis drug (ATD) Objective: The objective of this research is  to study the relationship between patients adherence in taking ATD determined by MMAS-8 questionnaire with QoL of patient determined by WHOQOL questionnaire. Method: Tuberculosis patients who undergo treatment for at least 4 weeks are the subjects in this study. This study was conducted by a cross-sectional method using the MMAS-8 and WHOQOL-BREF questionnaire of tuberculosis patients at Ibrahim Adjiand Gumuruh primary health care during March - August 2018. Result: Based on MMAS-8 questionnaire filled out by 75 patients, there was 69% of high adherence, 15% moderate,  and 16% has low adherence in taking ATD. Of the 6 characteristic factors (i.e., age, sex, occupation, income, education and length of treatment), only gender (p0.01) and occupation (p0.03) factors that influence the patient adherence significantly. Based on MMAS-8 and WHOQOL-BREF questionnaire analyses, there is only psychological health aspect (domain two) that have a significant (p = 0.01) correlated with patient adherence. Conclusion: Based on the results,the psychological health of tuberculosis patients play an important role in patient adherence. 
Co-Authors A. Mu’thi Andy Suryadi Abd. Ghiaz Putra Ramadan Ahmad Adati, Agnesia Ade Ari Puspitadewi Ahmad Rifly Suleman Akuba, Juliyanti Andi Makkulawu Andini Putri Sabihi Arini Arini Aziz, Rezky Nur Begali, Musdhalifah M. Bumulo, Mohamad Ramdan Rahmat Chinta Suryaningrum Dewi Rahmawaty Moo Dr. Apt. Hamsidar Hasan S.Si.,M.Si Elvie F Dungga Endah Nurrohwinta Djuwarno Erika Dami Fazril Pakaya, Mohamad Fhigra Marfiah Fika Nuzul Ramadhani Gunawan, Selvi Ayu Setiaarini Gusti Pandi Liputo Hiola, Faramita Hiola, Paramita Immaculata, Maria Intan Nusi Ishak Isa Julianty Akuba Kadaria Toana Kahar, Oktaviani Kasim, Sesha Ramadhani Kongkolu, Sitty Rahma Hutami Latif, Multiani S. Lia Amalia Madania, Madania Mahdalena Sy Pakaya Maimun Datau Makkulawu, Andi Mohamad Adam Mustapa Mubaraq, Fajar Saril Muhammad Taupik Muhammad Taupik Nabila Novreini Djunaidi Nur Ain Thomas Nur Rasdianah Nur'ain Dj. Silaka Nurhayati Salam Qarlan Pratama, Mohammad Rahmatia Samatowa Robert Tungadi Rukmawati, Iis Sri Wahyuni Suleman, Windy Riani Teti Sutriati Tuloli Teti Sutriyati Tuloli Tri Septian Maksum Widy Susanti Abdulkadir Widy Susanti Abdulkadir Widy Susanti Abdulkadir Widysusanti Abdulkadir Wiwit Zuriati Uno Yuni Sarah Manoppo Zahra Zakia, Wavika Zulkarnain Marhaba Zuriati Uno, Wiwit