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GAMBARAN KADAR HEMOGLOBIN PADA PENDERITA HIV DENGAN PENGOBATAN ANTIRETROVIRAL DI KOTA KENDARI Heni Umar; Ani Umar
Jurnal Analis Kesehatan Kendari Vol. 4 No. 1 (2021): Jurnal Analis Kesehatan Kendari (JAKK : Vol. 4 (1) Desember 2021)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46356/jakk.v4i1.169

Abstract

ABSTRAK Human Immunodeficiency Virus (HIV) merupakan retrovirus yang menyerang sistem kekebalan tubuh manusia. Penderita HIV harus memakai obat ARV seumur hidup yang berfungsi untuk mencegah replikasi virus HIV di dalam tubuh. Efek samping dari penggunaan obat antiretroviral akan dalam jangka lama akan cenderung menekan sel darah merah atau menghambat pertumbuhan sel-sel hematopoetik pada sumsum tulang penderita HIV/AIDS, sehingga mengalami penurunan kadar Hemoglobin. Penelitian ini dilaksanakan di Laboratorium Klinik Politeknik Bina Husada Kendari pada bulan Maret-April 2019. Tujuan dari penelitian ini untuk mengetahui hasil pemeriksaan kadar hemoglobin pada pasien HIV dengan pengobatan antiretroviral di Kota Kendari. Jenis penelitian yang digunakan adalah deskriptif dengan melakukan pemeriksaan kadar hemoglobin pada 20 sampel penderita HIV/AIDS menggunakan metode autoanalyzer. Dengan teknik pengambilan sampel secara accidentalsampling yaitu siapa saja yang bertemu dengan peneliti dapat digunakan sebagai sampel. Hasil penelitan diperoleh kadar hemoglobin yang normal sebanyak 14 orang (70%), dan kadar hemoglobin rendah sebanyak 6orang (30%). Jenis kelamin laki-laki lebih dominan dibanding perempuan yaitu jumlah pasien laki-laki sebanyak 15 orang (75%) dan perempuan sebanyak 5 orang (25%). Kata Kunci : HIV, AIDS, Antiretroviral, Hemoglobin ABSTRACT Human Immunodeficiency Virus (HIV) is a retrovirus that attacks the human immune system. HIV sufferers must take lifelong antiretroviral drugs used to prevent the replication of the HIV virus in the body. Side effects from the use of Antiretroviral drugs will tend to suppress red blood cells or inhibit the growth of hematopoietic cells in the bones of people with HIV / AIDS, resulting in a low decrease in hemoglobin. This research was carried out at the Hematology Laboratory of Bina Husada Polytechnic Kendari in March-April 2019. The purpose of this study was to determine the results of hemoglobin level examination in HIV patients with antiretroviral treatment in Kendari City. The type of research used was descriptive by examining Hemoglobin levels in 20 samples of HIVAIDS patients using the autoanalyzer method. With sampling teachniques using accidental sampling whoever meets the researcher can be used as a sample. The results showed that normal hemoglobin levels as much 14 people (70%) and low Hemoglobin levels as much 6 people (30%). Male sex is more dominant than women, namely the number of male patients is 15 people (75%) and women are 5 people(25%). Keywords : HIV, AIDS, Antiretroviral, Hemoglobin
GAMBARAN GLUKOSA URINE DAN KETON URINE PASIEN HIPERTENSI DI RUMAH SAKIT UMUM DAERAH KOTA KENDARI Susanti Susanti; Ani Umar; Ephi Trianti
Jurnal Analis Kesehatan Kendari Vol. 4 No. 2 (2022): Jurnal Analis Kesehatan Kendari (JAKK : Vol. 4 (2) Juni 2022)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46356/jakk.v4i2.184

Abstract

Hypertension is an increase in systolic blood pressure of at least 140 mmHg and a diastolic pressure of at least 90 mmHg. Urine is product of is end of system of metabolik released by kidney as remains or discard. Urine glucose is a simple sugar group that still in the urine after passing through various processes in the kidneys. Ketones is a metabolic product of fatty acids and proteins consisting of three compounds namely acetoacic acid, acetone, and beta hydroxybutyrate acid. Urine test can provide information about organabnormalities, but it can also be used to establish the result of treatment especially to monitor the development of disease such as high blood pressure (hypertension). Study aims to determine the description of glucose urine and ketone urine with patient hypertension. This type of research is descriptive by using device "study sectional cross" with sampling technique purposive sampling where the number of samples of 30 people. Based on the results of a study of 30 glucose urine and keton urine in patients hypertension at city general hospital kendari obtained normal urine glucose as many 5 patients (16,7%) and abnormal urine glucose 25 patients (83,3). While, ketone normal as many 30 patients (100%). Keywords : Hypertension, Glucose Urine, Keton Urine
PROFIL KOLESTEROL TOTAL PADA PENDERITA PENYAKIT JANTUNG KORONER DI RUMAH SAKIT UMUM DAERAH KOTA KENDARI Ani Umar; firdayanti firdayanti; Nur Hijreah Samsu
Jurnal Analis Kesehatan Kendari Vol. 5 No. 1 (2022): Jurnal Analis Kesehatan Kendari (JAKK) : Vol. 5 (1) Desember 2022)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46356/jakk.v5i1.215

Abstract

Total Cholesterol profile in patients with coronary heart disease at the city general hospital in kendari”. Coronary heart disease is one of the three main causes of death in the world each years. PJK is a disease that arises due to narrowing or blockage of arteries that enter the bloodstream to the heart muscle so that there is a lack of oxygen supply to the heart muscle. Total cholesterol is the total amount of cholesterol in the blood. Examination of total cholesterol which is a blood test that functions to determine total cholesterol levels in patients with coronary heart disease. The purpose of this study was to determine the total cholesterol profile in patients with coronary heart disease in the general hospital area of the city of kendari with enzymatic kinetic methods. Samples of patients with coronary heart disease as many as 18 samples with sampling techniques namely accidental sampling. Based on the research that has been done obtained results that there are 5 people (27%) have level ≥ 200 mg/dL shows an increase in total cholesterol levels and 13 people (72%) have level ≤ 200 mg/dL showing normal cholesterol levels. Key Words : Coronary Heart Disease, Total Cholesterol, Examination of Total Cholesterol.
SKRINING FITOKIMIA DAN UJI DAYA HAMBAT EKSTRAK PAKKAT UMBUT ROTAN (Callamus Caesius Blume) TERHADAP PERTUMBUHAN Staphylococcus aureus Ani Umar; Angriani Fusvita; Sri Rahayu
Jurnal Analis Kesehatan Kendari Vol. 5 No. 2 (2023): Jurnal Analis Kesehatan Kendari (JAKK) : Vol. 5 (2) Juni 2023)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46356/jakk.v5i2.253

Abstract

ABSTRACT Rattan tubers (Calamus caesius Blume) is a traditional food taken from the inside of young rattan which is usually used as vegetables. The growth of Staphylococcus aureus bacteria can be inhibited by the content of various chemical compounds in various plants such as rattan shoots. The rattan shoots contain saponins and alkaloids. This study aims to determine the phytochemical screening and test the inhibition of rattan root extract (Callamus Caesius Blume) on the growth of Staphylococcus aureus. The type of research carried out was an experiment with rattan umbut extract treated as a test of inhibition of the growth of Staphylococcus aureus ATCC 25923. 500 grams of rattan umbut pakkat extract was obtained by maceration method for 5 days. In this study using the Kirby Bauer method (disk diffusion). The results showed that the chemical compounds contained in the rattan umbut pack were alkaloids and saponins, while in the inhibition test there was no clear zone around the paper disk which indicated that the rattan umbut pack extract could not inhibit the growth of Staphylococcus aureus with a concentration of 5%, 10%, 15% , and 100% . Key words: Inhibition zone, rattan root extract, Staphylococcus aureus ABSTRAK Pakkat umbut rotan (Calamus caesius Blume) adalah makanan tradisional yang diambil dari bagian dalam rotan muda yang biasanya dijadikan sayur-sayuran. Pertumbuhan bakteri Staphylococcus aureus dapat dihambat oleh kandungan senyawa kimia yang beragam pada berbagai tumbuhan seperti umbut rotan. Umbut rotan tersebut memiliki senyawa saponin dan alkaloid. Penelitian ini bertujuan untuk mengetahui skrining fitokimia dan uji daya hambat ekstrak pakkat umbut rotan (callamus Caesius Blume) terhadap pertumbuhan Staphylococcus aureus. Jenis penelitian yang dilakukan adalah eksperimen dengan ekstrak pakkat umbut rotan diberikan perlakuan sebagai uji daya hambat terhadap pertumbuhan Staphylococcus aureus ATCC 25923. Ekstrak pakkat umbut rotan sebanyak 500 gram diperoleh dengan metode maserasi selama 5 hari. Pada penelitian ini menggunakan metode Kirby bauer (difusi disk). Hasil penelitian menunjukan bahwa senyawa kimia yang terdapat pada pakkat umbut rotan adalah alkaloid dan saponin sedangkan pada uji daya hambat tidak terdapat zona bening disekitar paper disk yang menandakan ekstrak pakkat umbut rotan tidak dapat menghambat pertumbuhan Staphylococcus aureus dengan konsentrasi 5%, 10%, 15%, dan 100% . Kata kunci: Zona Hambat, ekstrak pakkat umbut rotan, Staphylococcus aureus
Analysis of blood calcium levels in calcium water consumers Rubak, Bonni; Umar, Ani; Reymon, Reymon; Jannah, Nanda Reski
Jurnal Ilmiah Kesehatan Sandi Husada Vol 13 No 2 (2024): Jurnal Ilmiah Kesehatan Sandi Husada
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat Akademi Keperawatan Sandi Karsa (Merger) Politeknik Sandi Karsa

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35816/jiskh.v13i2.1216

Abstract

Introduction: Water is a primary and basic human need. One of the chemical parameters that must be met for drinking water needs is mineral content, such as calcium and magnesium. Water hardness is a condition in which there is excessive calcium and magnesium content, which is commonly known as calcareous water. If consumed long-term, high-water hardness that exceeds normal limits can interfere with body health. Specifically, excess calcium in the body can cause hypercalcemia, hyperparathyroidism, kidney stones, and muscle tissue damage (muscle weakness). Objective: This study aims to determine blood calcium levels in individuals who consume calcareous healthy water. Methods: The type of research used is descriptive-analytical, with blood calcium level analysis carried out using the Ion Selective Electrode (ISE) method through the Electrolyte Analyzer (CBS400). Result: Based on the results of the study, it was obtained that blood calcium levels in 30 community respondents in Ranomeeto District (100%) were above the reference value, indicating high blood calcium levels. Conclusion: blood calcium levels in people who consume lime juice indicate high blood calcium levels. Consuming water with a high lime content can hurt health. Therefore, people need to consider the quality of the drinking water they drink, especially those that have a high lime content, to maintain heart and kidney health in the long term.
Prevalensi Jenis Kelamin dan Usia Pasien Suspek Tuberkulosis (TB) Terhadap Hasil Pemeriksaan Tes Cepat Molekuler (TCM) Menggunakan GeneXpert di RSUD Bahteramas Darmayanita Wenty; Ani Umar; Heni Umar; Fika
Jurnal Analis Kesehatan Kendari Vol. 7 No. 2 (2025): Jurnal Analis Kesehatan Kendari (JAKK) : Vol. 7 (2) Juni 2025)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46356/jakk.v7i2.353

Abstract

Tuberculosis (TB) is one of the infectious diseases that is still a global health problem, including in Indonesia. Examination using Molecular Rapid Test (TCM) is an effective method in detecting TB and resistance to rifampicin. This study aims to determine the prevalence of gender and age of suspected TB patients against the results of TCM examination at Bahteramas Hospital. This study is a quantitative descriptive study with a retrospective approach. Data were obtained from the results of TCM examinations on 309 suspected TB patients conducted at Bahteramas Regional Hospital. The variables analyzed included age, gender, and TCM results, which were categorized as Rifampicin Sensitive (Rif Sen), Rifampicin Resistant (Rif Res), and Negative. The results of this study are that of the 309 patients, the majority were over 46 years old (60.2%) and male (54.4%). The results of the TCM examination showed that 59 patients (19.1%) were detected with rifampicin-sensitive TB, 9 patients (2.9%) with rifampicin-resistant TB, and 241 patients (78%) had negative results. Most patients with positive TB results came from the age group >46 years and were male. The conclusion of this study is that there is a tendency that elderly and male patients have a higher prevalence of positive TCM results. These results indicate the importance of active screening and early detection in certain age groups and genders for TB control.
Pencegahan Kecacingan Melalui Pendampingan Pembiasaan Pola Hidup Bersih Sehat dan Pemeriksaan Kecacingan pada Anak-Anak Di SD Negeri 3 Konawe Selatan: Pencegahan Kecacingan Melalui Pendampingan Pembiasaan Pola Hidup Bersih Sehat dan Pemeriksaan Kecacingan pada Anak-Anak Di SD Negeri 3 Konawe Selatan Aulya, Muhammad Sultanul; Idris, Sri Aprilianti; Fusvita, Angriani; firdayanti, Firdayanti; Fusvita; Umar, Ani; Idris, Kemal; Wenty, Darmayanita
Jurnal Pengabdian Magister Pendidikan IPA Vol 6 No 4 (2023): Oktober-Desember 2023
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpmpi.v6i4.6202

Abstract

Worm infections caused by Soil Transmitted Helminth (STH) are intestinal nematode worms which are transmitted through the soil in their life cycle. The various kinds of nematode class worms that are known are roundworms (Ascaris Lumbricoides), whipworms (Trichuris trichiura) and hookworms (Ancylostoma duodenale and Necator americanus). Worms have a very bad effect on health, in children worms will have an impact on learning disorders, decreased quality of intelligence and reduced nutritional intake. The aim of this community service activity is to provide socialization on the prevention of worms through assistance in getting used to a clean, healthy lifestyle and checking for worms among children at SD Negeri 3 Konawe selatan. The respondents in this activity were children at SD Negeri 3 Konawe selatan and 31 stool samples were obtained. The results of stool examination using the direct method on 31 children's stool samples did not find positive samples and 31 children's stool samples did not contain intestinal nematode worm eggs.
UJI DAYA HAMBAT EKSTRAK DAUN KEDONDONG (Spondias dulcis L.) TERHADAP PERTUMBUHAN JAMUR Aspergillus flavus Umar, Ani; jumiati, jumiati; Yuniar, Viranda
Jurnal Analis Kesehatan Kendari Vol. 6 No. 1 (2023): Jurnal Analis Kesehatan Kendari (JAKK) : Vol. 6 (1) Desember 2023)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46356/jakk.v6i1.281

Abstract

ABSTRACT Different chemical compounds in various plants such as leaves. One of an alternative vegetable material that has the potential to have activity as antifungi is a leaf of kedondong. The leaves have saponin compounds, alkaloids and tannins. This study aims to determine the inhibitor power of leaves kedondong (Spondias dulcis L.) to Aspergillus flavus and to determine the concentration of leaf extract kedondong (Spondias dulcis L.) which effectively inhibits the growth of Aspergillus flavus fungus. Types of research is experiments with the extract of the given kedondong leaf treatment as an inhibitory test againts Aspergillus flavus growth. Kedondong leaf extract obtained by maseration method for 5 days and this research uses Kirby bauer method (diffusion disk). The results showed that there is no clear zone around the disc paper indicating the extract of the kedondong leaf can not be inhibits the growth of Aspergillus flavus with concentrations of 5%, 10%, and 15%. Keywords : Inhibition Zones, Kedondong Leaves, Aspergillus flavus. ABSTRAK Pertumbuhan jamur Aspergillus flavus dapat dihambat oleh kandungan senyawa kimia yang beragam pada berbagai tumbuhan seperti daun. Salah satu alternatif bahan nabati yang berpotensi mempunyai aktivitas sebagai antifungi adalah daun kedondong. Daun tersebut memiliki senyawa saponin, alkaloid dan tannin. Penelitian ini bertujuan untuk mengetahui daya hambat daun kedondong (Spondias dulcis L.) terhadap jamur Aspergillus flavus dan untuk menentukan konsentrasi ekstrak daun kedondong (Spondias dulcis L.) yang efektif menghambat pertumbuhan jamur Aspergillus flavus. Jenis penelitian yang dilakukan adalah eksperimen dengan ekstrak daun kedondong diberikan perlakuan sebagai uji daya hambat terhadap pertumbuhan Aspergillus flavus. Ekstrak daun kedondong diperoleh dengan metode maserasi selama 5 hari dan penelitian ini menggunakan metode Kirby bauer (difusi disk). Hasil penelitian menunjukan bahwa tidak terdapat zona bening disekitar paper disk yang menandakan ekstrak daun kedondong tidak dapat menghambat pertumbuhan Aspergillus flavus dengan konsentrasi 5%, 10%, dan 15%. Kata kunci : Zona Hambat, Daun Kedondong, Aspergillus flavus
GAMBARAN JUMLAH ERITROSIT PADA PASIEN SUSPEK COVID-19 DI RSUD KOTA KENDARI Umar, Ani; Wenty, Darmayanita; Salni, Salni
Jurnal Analis Kesehatan Kendari Vol. 6 No. 2 (2024): Jurnal Analis Kesehatan Kendari (JAKK) : Vol. 6 (2) Juni 2024)
Publisher : Program Study of Medical Laboratory Technology , Politeknik Bina Husada Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46356/jakk.v6i2.305

Abstract

ABSTRACT Red blood cell or called Erythrocyte is red blood that has the most number of blood cells in the human body. The number of red blood cells can provide information that indicates the presence of hematological disordes. Hematological disorder is interference with the formation of red blood cells, including a decrease and increase in the number of cells (polycythaemia). Reduction in the number of red blood cells is found in chronic diseases, such as: liver disease, anemia, and leukemia, while polycythemia is found in patients with diarrhea, severe dehydration, burns, and heavy bleeding. The purpose of this study was to determine description of erythrocyte amounts in covid-19 suspected patients by using descriptive research, and sampling with total sampling from June -July 2020. The sample of this study was the result of examination of the number of erythrocytes in patients with suspected Covid-19. The results of the study provided a high number of erythrocytes found in patients with suspected Covid-19, as many as 7 patients (26%), the number of erythrocytes in patients with suspected Covid-19 was low, as many as 1 patient (4%), and the normal erythrocytes in patients with suspected Covid-19 was 19 patients (70%). key words: Erythrocyte, Covid-19, Number of Erythrocytes. ABSTRAK Sel darah merah atau disebut juga eritrosit merupakan sel darah yang jumlahnya terbanyak dalam tubuh manusia. Jumlah sel darah merah dapat memberikan informasi yang mengindikasikan adanya gangguan sel darah. Gangguan sel darah adalah gangguan pada pembentukan sel darah merah, meliputi penurunan dan peningkatan jumlah sel (polisitemia). Penurunan jumlah sel darah merah ditemukan pada penyakit kronis, seperti penyakit hati, anemia, dan leukemia, sedangkan polisitemia ditemukan pada penderita diare, dehidrasi berat, luka bakar, maupun pendarahan berat. Tujuan penelitian ini untuk mengetahui gambaran jumlah eritrosit pada pasien suspek Covid-19. Jenis penelitian ini adalah deskriptif dan pengambilan sampel dilakukan dengan total sampling yang merupakan data suspek Covid-19 di RSUD Kota kendari pada bulan juni-juli 2020. Sampel penelitian ini adalah data hasil pemeriksaan jumlah eritrosit pasien suspek Covid-19. Hasil penelitian menunjukkan jumlah eritrosit yang tinggi dijumpai pada pasien suspek Covid-19 yaitu 7 pasien (26%), jumlah eritrosit pada pasien suspek Covid-19 yang rendah yaitu 1 pasien (4%), dan jumlah eritrosit yang normal pada pasien suspek Covid-19 yaitu 19 pasien (70%). Kata Kunci : Eritrosit, Covid-19, Jumlah Eritrosit.
Analysis of the Potential of Platelet Indices as a Predictor of Hematological Comorbidity in Patients with Diabetes Mellitus Umar, Ani; Wenty, Darmayanita; Firdayanti; Susanti; Umar, Heni
Public Health of Indonesia Vol. 11 No. 4 (2025): October - December
Publisher : YCAB Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/phi.v11i4.1591

Abstract

Background: Diabetes Mellitus (DM) is one of the chronic diseases that is a global burden. The increase in DM cases poses a risk of complex comorbidities such as cardiovascular disease, kidney disease and hematological disorders. The Platelet indices (MPV, PDW, PCT, P-LCR) reflects platelet activation and has the potential to be a biomarker for predicting comorbidities, so it can help improve the quality of clinical management in DM patients. Objective: This study aims to evaluate the predictive potential of platelet indices as a biomarker of comorbidity hematology in DM patients. Methods: An analytical study with a cross-sectional design was conducted from June to July 2025 at the Bahteramas Regional Hospital, Indonesia, involving 100 patients with diabetes mellitus and 100 healthy individuals as controls selected through purposive sampling. Venous blood samples were taken from all participants to measure platelet indices (PLT, MPV, PDW, P-LCR) using an automated hematology analysis tool. Data analysis was carried out by an independent sample t-test to compare index values between groups, as well as an ROC curve to evaluate its predictive value against DM status, Statistical significance was set at p < 0.05. Results: showed that the mean platelet indices in the group of healthy individuals with PLT was 229.98 ×10³/μL and in DM patients with a mean value of 260.71 ×10³/μL, MPV in healthy individuals with MPV was obtained at 10.24 fL. In DM it rises to 10.46 fL. The PDW value in healthy individuals was 9.82 fL. In DM the average value increased to 11.80 fL, in Healthy Individuals PCT averaged 24.7%, In DM the value increased to 28.7%. The P-LCR value in healthy individuals was 22.12%. In DM, the average value increased to 25.80%, with a significant value of P< 0.05 which shows that between healthy patients and DM patients there is a significant difference in terms of PLT, MPV, PDW, PCT and P-LCR parameters. The ROC curve of each platelet parameter (PLT, MPV, PDW, PCT, and P-LCR) illustrates the sensitivity and specificity of the model in predicting the occurrence of comorbidities. This can be obtained from the Under the Curve Area Value (AUC) which shows that PDW has the highest AUC of 83.4%, which indicates the ability of the most effective parameters in predicting comorbidities in DM patients. Conclusions: This study shows that platelet indices, especially PDW values, has the most effective potential as a practical and easily accessible hematological biomarker for predicting comorbidity risk in patients with diabetes mellitus. These results confirm the role of the predictive value of platelet indices in early detection and risk stratification, which can support more proactive clinical decision-making and management of DM patients.