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All Journal Jurnal Ilmiah Aplikasi Isotop Radiasi Medika Tadulako IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) al-Afkar, Journal For Islamic Studies Jurnal Ilmiah Kesehatan QARDHUL HASAN: MEDIA PENGABDIAN KEPADA MASYARAKAT Jurnal Ekonomi Bisnis Indonesia Jurnal Abdimas Madani dan Lestari (JAMALI) Edu Masda Journal Lumbung Inovasi: Jurnal Pengabdian Kepada Masyarakat Indonesian Journal of Health Science Jurnal Pijar MIPA Indonesian Journal of Medical Chemistry and Bioinformatics Jurnal Inovasi Pengabdian dan Pemberdayaan Masyarakat Jurnal Adijaya Multidisiplin Jurnal Farmasi Kryonaut Therapy : Journal of Health Science ISTA Online Technologi Journal Jurnal Kesehatan Sundaram
Siva Fauziah, Siva
Institut Sains Dan Teknologi Al-Kamal
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THE INFLUENCE OF DIFFERENCES IN THE CONCENTRATION OF 70% ETHANOL EXTRACT OF YARROW LEAVES (Achillea millefolium L) IN GEL FORMULATION ON PHYSICAL PROPERTIES, PHYSICAL STABILITY, AND ANTIBACTERIAL ACTIVITY AGAINST Pseudomonas aeruginosa IN VITRO Nasar, Nur Afni Syariah; Nafisah, Lina; Fu'adah, Intan Tsamrotul; Pomalingo, Dwina Ramadhani; Fauziah, Siva
Edu Masda Journal Vol 9, No 2 (2025): EDU MASDA JOURNAL
Publisher : STIKes Kharisma Persada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52118/edumasda.v9i2.297

Abstract

                                                 ABSTRACTMany infections are caused by bacteria, viruses, fungi, or other minor groups. One of the bacteria that can cause skin infections is Pseudomonas aeruginosa. Yarrow (Achillea millefolium L) is a plant that is empirically used to treat bleeding wounds on the skin. This research was conducted by testing the antibacterial activity of 70% ethanol extract and in gel dosage form at concentrations of 5%, 10%, and 15% using the disc diffusion method. The reference substance/positive control used is gentamicin, and the negative control is sterile distilled water. The research results show that antibacterial activity at a concentration of 5% provides an inhibition zone against Pseudomonas aeruginosa bacteria of 16.46 mm, while the gel formulation at a concentration of 15% effectively inhibits the growth of Pseudomonas aeruginosa bacteria with an inhibition zone of 22.69 mm. Stability testing of the gel formulation during storage did not show any changes in colour, taste, odour, or form organoleptically. Homogeneous gel preparations with appropriate pH, spreadability, and viscosity remained stable for 28 days at different temperatures.                                           ABSTRAKBanyak infeksi disebabkaan oleh bakteri virus, jamur, atau beberapa kelompok minor lainnya. Salah satu bakteri yang dapat menyebabkan infeksi kulit adalah bakteri Pseudomonas aeruginosa. Daun Seribu (Achillea millefolium L) merupakan tumbuhan yang secara empiris digunakan untuk mengobati luka pendarahan pada kulit. Penelitian ini dilakukan dengan uji aktivitas antibakteri terhadap ekstrak etanol 70% dan dalam bentuk sediaan gel dengan konsentrasi 5%, 10% dan 15% dengan menggunakan metode difusi cakram. Sebagai zat pembandingnya/Kontrol positif yang digunakan adalah gentamicin dan sebagai kontrol negatif adalah aquadest steril. Hasil penelitian  menunjukan bahwa aktivitas antibakteri dengan konsentrasi 5% memberikan zona hambat pada bakteri Pseudomonas aeruginosa  16,46 mm sedangkan dalam bentuk sediaan gel dengan konsentrasi 15% efektif menghambat pertumbuhan bakteri Pseudomonas aeruginosa dengan zona hambat 22,69 mm. Uji stabilitas sediaan gel  pada penyimpanan secara organoleptik tidak terjadi perubhan warna, rasa, bau dan bentuk. Sediaan gel homogen dengan pH, daya sebar dan viskositas sesuai selama 28 hari dengan suhu yang berbeda.
Swamedikasi, DAGUSIBU, dan Waspada Bahan Berbahaya Kosmetik: Pengabdian Masyarakat di Dusun Kepuhsari, Surakarta: Indonesia Ainurofiq, Ahmad; Fatimi, Hana Anisa; Prabowo, Imam; Larasati, Rizky Dwi; Choiri, Syaiful; Az Zahro, Fatimah Aqilah; Usmarini, Razita Fathya; Maharani, Vania; Fauziah, Siva; Purbowati, Dwi; Rinaldi, Rafli; Jauhari, Muh Rizqi Fadlah
Jurnal Abdimas Madani dan Lestari (JAMALI) Volume 08, Issue 1, Maret 2026
Publisher : UII

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/jamali.vol8.iss1.art18

Abstract

Inappropriate self-medication limited public understanding of the DAGUSIBU (Dapatkan, Gunakan, Simpan, dan Buang) concept, and the widespread use of harmful cosmetic products remain major challenges in improving community health. This community service activity aimed to increase the knowledge of residents in Dusun Kepuhsari RW 38 regarding rational self-medication, proper application of the DAGUSIBU principle (Get, Use, Store, and Dispose of Medicine Correctly), and the risks associated with hazardous cosmetic ingredients. The activity was carried out through an educational and participatory approach consisting of a pretest, leaflet distribution, direct delivery of material by resource persons, interactive Q&A sessions, distribution of door prizes, and a posttest. The results showed an overall increase in participants' understanding across all three topics. Knowledge of self-medication increased by 1.2 times, while understanding of DAGUSIBU improved by 1.44 times. Education on harmful cosmetics also led to a significant improvement in participants' awareness of product legality, identification of dangerous substances, and associated health risks. Through this educational program, the community is expected to become more informed and responsible in using both medicines and cosmetics safely and wisely.
Antibacterial activity of deodorant stick formula from ethyl acetate fraction of beluntas leaves (Pluchea indica L.) against Pseudomonas aeruginosa and Streptococcus pyogenes bacteria that cause body odor. Yulis Adriana; Siva Fauziah
IJFAC (Indonesian Journal of Fundamental and Applied Chemistry) Vol 10, No 1 (2025): February 2025
Publisher : IJFAC (Indonesian Journal of Fundamental and Applied Chemistry)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Beluntas contains flavonoids, tannins and steroids which can inhibit growth and reduce the risk of infection by microorganisms. Empirically, beluntas leaves are used by people to overcome unpleasant body odor, usually body odor is caused by the Pseudomonas aeruginosa and Streptococcus pyogenes. Stick deodorant is a cosmetic made from; sodium stearate (steric acid and sodium hydroxide) and as a solvent using propylene glycol. The aim of this research was to formulate the ethyl acetate fraction of beluntas leaves into a stick deodorant and test the antibacterial activity of Pseudomonas aeruginosa and Streptococcus pyogenes using the well diffusion method and test physical, chemical and quality parameters. microbiology. Stick deodorant were made into three formulations with different concentrations of the ethyl acetate fraction of beluntas leaves, namely Formula I with a concentration of 20%, Formula II is 30% and Formula III is 40% with the harding agent stearic acid: NaoH 10% (8.5:7.5). The quality test of the three formulation sticks deodorants met the requirements for pH test (range 6-7.0), homogeneity test, melting point test (range 55.40-60.9 °C), Microbiology test and water capacity test (aw). The results of the inhibition test against Streptococcus pyogenes were between 23.33-8.33 mm in the very strong inhibition category, the comparison deodorant had no inhibitory area and gentamycin 0.01% as a positive control had an inhibitory area of 29.66 mm in the very strong category. The inhibitory power against Pseudomonas aeruginosa is 11.5-18.92 mm in the strong inhibitory category, the comparison deodorant has no inhibitory area and 0.01% gentamycin as a positive control has inhibitory area of 21.66 mm in the very strong category.Keywords: Ethyl acetate fraction, stick deodorant, Pluchea indica.L, Pseudomonas aeruginosa, Streptococcus pyogenes, inhibition test
UJI AKTIVITAS ANTIOKSIDANDAN PENETAPAN KADAR FLAVONOID TOTALDARI EKSTRAK ETANOL 70% DAUN KAPUK RANDU (CEIBA PENTANDRA(L.)GEARTN) DENGANMETODE DPPH Siva Fauziah; Nova Puspita Sari
IONTech Journal Vol. 1 No. 1 (2020): Agustus 2020
Publisher : Institut Sains dan Teknologi Al-Kamal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62702/ion.v1i1.23

Abstract

Abstrak Daun kapuk randu mengandung senyawa flavonoid yang memiliki aktivitas sebagai antioksidan. Penelitian ini bertujuan untuk menetapkan kadar flavonoid totaldan menguji aktivitas antioksidan dari ekstrak etanol 70% daun kapuk randu (Ceiba pentandra (L.)Gaertn.) dengan menggunakan spektrofotometer UV-Vis. Penentuan kadar flavonoid total ekstrak etanol 70% daun kapuk randu (Ceiba pentandra (L.)Gaertn.) ditentukan berdasarkan nilai absorbansi yang diukur pada panjang gelombang sinar tampak 429,0 nm dengan menggunakan pembanding kuersetin. Uji akivitas antioksidan ekstrak etanol 70% daun kapuk randu (Ceiba pentandra (L.)Gaertn.) ini dilakukan dengan mengukur aktivitas peredaman ekstrak terhadap radikal DPPH (1,1-difenil-2-pikrilhidrazil) secara spektrofotometer UV-Vis pada panjang gelombang 515,0 nm. Hasil penelitian menunjukan kadar flavonoid total yang diperoleh pada ekstrak etanol 70% daun kapuk randu yaitu12,69%. Hasil dari uji aktivitas antioksidan ekstrak etanol 70% daun kapuk randu diperoleh nilai IC50 sebesar 59,296 ppm. Disimpulkan bahwa ekstrak etanol 70% daun kapuk randu memiliki potensi sebagai antioksidan yang kuat. Abstract Kapok leaves contain flavonoid compounds which have antioxidant activity. Research of determination of total flavonoid content and antioxidant activity of 70% ethanol extract in kapok leaf (Ceiba pentandra (L.)Gaertn.) by using UV-Vis spectrophotometer. Determination of total flavonoid levels of 70% ethanol extract kapok leaf (Ceiba pentandra (L.)Gaertn.) Extract was determined based on the absorbance value measured at the wavelength of visible light 429.0 nm using a comprator quercetin. Antioxidant activity test for ethanol 70% kapok leaf extract (Ceiba pentandra (L.)Gaertn.) was carried out by measuring the reducing activity of the extract against DPPH radical (1,1-diphenyl-2-picrylhydrazyl) by UV-Vis spectrophotometer at a wavelength of 515.0 nm. The results showed total flavonoid levels obtained on70% ethanol extract kapok leaf (Ceiba pentandra (L.)Gaertn.) is 12,69%. The results of the kapok leaf antioxidant activity test obtained IC50 values in 70% ethanol extract kapok leaf (Ceiba pentandra (L.)Gaertn.) is59,296 ppm. It was concluded that 70% ethanol extract kapok leaf (Ceiba pentandra (L.)Gaertn.) it has potential as a powerful antioxidant.
IDENTIFIKASI DRUG RELATED PROBLEMS (DRPs) PADA PASIEN HIPERTENSI DENGAN PROGRAM RUJUK BALIK (PRB) DI INSTALASI RAWAT JALAN RUMAH SAKIT MEDIKA BSD TANGERANG SELATAN PERIODE JANUARI – MARET 2020 Boy Yunaidy; Silvia Anggraeni; Iyan Hardiana; Aulia Zahra; Dede Komarudin; Siva Fauziah
Jurnal Kesehatan Sundaram Vol. 1 No. 1 (2024): JKS
Publisher : LPPM STIKes Buleleng

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52073/t5r8s868

Abstract

Hipertensi merupakan peningkatan tekanan darah sistolik di atas batas normal >140mmHg dan diastolik >90mmHg. Di Eropa, 37% - 55% orang dewasa mengalami hipertensi. Di Indonesia 8,4% jumlah penduduknya menderita hipertensi dan prevalensi tertinggi yaitu Sulawesi Utara 13,2% Tujuan penelitian ini mengetahui presentase Drug Related Problems (DRPs) kategori ketidaktepatan dosis dan interaksi obat pada pasien Hipertensi PRB rawat jalan di Poli Jantung RS Medika BSD Tangerang Selatan. Penelitian ini merupakan penelitian non eksperimental deskriptif menggunakan data retrospektif untuk memperoleh gambaran obat antihipertensi yang digunakan pasien PRB rawat jalan di poli jantung Rumah Sakit Medika BSD Tangerang Selatan periode Januari-Maret 2020. Penelitian dilakukan di Instalasi Rekam Medik RS Medika BSD Tangerang Selatan selama 3 bulan mulai November 2020 - Januari 2021. Sampelnya pasien hipertensi program rujuk balik (PRB) yang berobat pada Januari - Maret 2020 ditentukan dengan metode purposive sampling. Kesimpulannya yaitu jumlah pasien PRB laki-laki 44 orang (88%) dan perempuan 12 orang (12%), kelompok umur terbanyak 50-59 tahun 40%. Obat hipertensi paling banyak digunakan Antagonis Reseptor Angiotensin II (Candesartan 16mg (33,33%)). Ketepatan dosis pada pasien 100% dengan jumlah pasien 50 orang. Interaksi Obat yang terjadi pada 48 pasien (96%) dan jumlah obat yang berinteraksi 222 obat (97,67%).
Co-Authors Adityo Hartono Ahmad Ainurofiq, Ahmad Amalia, Siska Andriansyah, Lucky Anggraeni, Anggi Sekar Aulia Zahra Az Zahro, Fatimah Aqilah Azwar Anas Badriah, Liah Boy Yunaidy Citra Dewi Dede Komarudin Devinda, Rinova Dinda Nur Fajri Hidayati Bunga Djoharsjah Djoharsjah Dwi Atmanto Dwi Purbowati Ekadipta Ekadipta Ermin Katrin Fatimi, Hana Anisa Febri Hidayat Ferial, Jihan Gina Aulia Hafiz, Muhamad Handono Handoyo Hendig Winarno Hernawati, Diana Herul, Herul Iin Hardiyati Imam Prabowo, Imam Intan Tsamrotul Fu’adah Iyon Muhdiyati Jauhari, Muh Rizqi Fadlah Kiki Deniati Larasati, Rizky Dwi Maharani, Vania Megan Asri Humaira Muftiyah, Alvi Nur Mulyani Putri, Anissa Mustika Tripatmasari Nada Widiyanti Nafisah, Lina Nasar, Nur Afni Syariah Nisa, Ima Vera Nova Puspita Sari NURINA AYUNINGTYAS Nurul Fauziah Paujiah, Lutfia Pomalingo, Dwina Ramadhani Puji Sari Putri D, Bunga Putri, Annisa Septyana Rafli Rinaldi Rahmawati, Rahmawati Ratih Pramintari Ruslihagi, Farid Sholihah, Anna Zahratas Silvia Anggraeni Siti Muti’ah, Siti Siti Nurbaya Susanto Susanto Syaiful Choiri Usmarini, Razita Fathya Veranita, Weri Yulis Adriana Yulis Adriana