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All Journal Pharmaciana: Jurnal Kefarmasian Pharmacology and Clinical Pharmacy Research Jurnal Ilmiah Farmako Bahari Jurnal Buana Farma Indonesian Journal of Community Empowerment
ASMAN SADINO, ASMAN
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Humanities Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Social Sciences Other

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TINJAUAN LITERATUR: AKTIVITAS FARMAKOLOGI DAN KANDUNGAN SENYAWA DARI KACANG KEDELAI (Glycine max L.) Sadino, Asman; Apriani, Riza; Solihah, Puspa Sari Dewi; Rachmawati, Siti
Jurnal Buana Farma Vol 5 No 4 (2025): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v5i4.1569

Abstract

Soybean (Glycine max L.) is a functional food from the legume group that is rich in bioactive compounds and has the potential to prevent degenerative diseases. This review aims to assess the content of the main active compounds and pharmacological activities of soybeans based on current scientific evidence. The method used is narrative review through literature searches on Google Scholar and PubMed databases of full-text articles published in the period 2010-2025. Articles included were in vitro and in vivo experimental studies that addressed the compound content and pharmacological activity of soybeans, while review articles, proceedings, and irrelevant publications were excluded. From the selection process, 12 articles were obtained that met the criteria for analysis. The results showed that isoflavones are the dominant compounds in soybeans that play a role in various pharmacological activities that can be grouped into several main categories, namely antioxidant and anti-inflammatory activities, metabolic activities (antidiabetes, antiobesity, and antihyperuricemia), and cardiovascular activities (antihypertension and anticholesterol). In addition, soy also shows potential as a supportive agent in the prevention of cancer and osteoporosis. Based on these findings, soy has great potential to be developed as a functional food and therapeutic support material in the prevention of degenerative diseases.
TINJAUAN LITERATUR: ETNOFARMASI DAN AKTIVITAS FARMAKOLOGI KULIT PISANG KEPOK (Musa paradisiaca formatypica) Sadino, Asman; Fadhlillah, Faizah Min; Hajar, Dhea Siti; Apriani, Riza
Jurnal Buana Farma Vol 6 No 1 (2026): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v6i1.1649

Abstract

Ethnopharmaceutical study is an approach to explore the local knowledge of people from certain tribes and ethnicities regarding the utilization of plants as traditional medicines. This review aims to examine the ethnopharmaceutical utilization and pharmacological activity of kepok banana peel waste (Musa paradisiaca formatypica) based on current scientific evidence. The method used was narrative review through literature searches on Google Scholar and PubMed databases of full-text articles published in the period 2011-2026. The keywords used included “ethnopharmaceutical,” “Musa paradisiaca,” “kepok banana peel”, and “pharmacological activity of Musa paradisiaca.” Included articles were national and international accredited/ISSN publications that addressed the ethnopharmaceutical aspects and pharmacological activity of kepok banana peel, while irrelevant articles and publications below 2011 were excluded. The results showed that kepok banana peel has been utilized as a traditional medicine by several ethnic groups in Indonesia, including Dondo, Kaili, Mori, Sasak, and Banggai. Pharmacologically, kepok banana peel is reported to have several main activities including antidiarrheal, anti-inflammatory, wound healing (cuts and burns), and anti-acne activity. Based on these findings, kepok banana peel waste has the potential to be developed as an ethnopharmaceutical-based traditional medicine ingredient and candidate raw material for pharmaceutical preparations supporting therapy.
TINJAUAN LITERATUR: AKTIVITAS ANTIDIABETES MELLITUS BEBERAPA TANAMAN FAMILI MALVACEAE Sadino, Asman; Nuari, Doni Anshar; Apriani, Riza; Muharam, Ceceng Fajar
Jurnal Buana Farma Vol 6 No 1 (2026): Jurnal Buana Farma
Publisher : Fakultas Farmasi Universitas Buana Perjuangan Karawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36805/jbf.v6i1.1650

Abstract

The Malvaceae family is a group of plants widely used empirically as traditional medicine to help control diabetes mellitus (DM) and has been supported by various experimental studies. This review aims to assess the types of Malvaceae family plants that have potential as antidiabetics and to summarize scientific evidence related to their pharmacological activity and the active compounds involved. The method used was a narrative review through a literature search in Google Scholar and PubMed for full-text articles published during 2011–2026. The included articles consisted of in vitro and in vivo studies discussing the antidiabetic or antihyperglycemic activity of Malvaceae family plants, while duplicate articles, review articles, proceedings, and irrelevant publications were excluded. Based on the selection process, several articles met the criteria for descriptive analysis. The results showed that several Malvaceae family plants have antidiabetic potential, including hibiscus (Hibiscus rosa-sinensis), roselle (Hibiscus sabdariffa), okra (Abelmoschus esculentus), durian (Durio zibethinus), sidaguri (Sida cordifolia), kapas hantu (Abroma augusta), biruan (Grewia asiatica), kapuk (Ceiba pentandra), kembang sore (Abutilon indicum), and pulutan (Urena lobata), all reported to have blood glucose-lowering effects. This activity is related to secondary metabolites such as flavonoids, alkaloids, tannins, saponins, and phenolic compounds, which act through antioxidant mechanisms, increased insulin sensitivity, inhibition of α-amylase and α-glucosidase enzymes, and protection of pancreatic β cells. Based on these findings, Malvaceae family plants have the potential to be developed as sources of natural medicine candidates and supportive therapies in the management of diabetes mellitus.
Co-Authors Anas Subarnas Apriani, Riza Apriliani, Nisa Siti Asri Dewi, Asri Astri Senania, Astri Atun Qowiyyah Cahyati, Effan Faizah Min Fadhlillah Hajar, Dhea Siti Hermawan, Belya Anindia Kanto, Dhini Annisa Rahmasari Karina Karina Mochammad Imron Awalludin Muchtaridi Muchtaridi Muharam, Ceceng Fajar Novriyanti Lubis, Novriyanti Nuari, Doni Anshar Nurhandayani, Yuni Rena Rena Renggana, Hesti Riska Prasetiawati, Riska Rohimah, Vina Siti Sahidin, Idin SITI RACHMAWATI Solihah, Puspa Sari Dewi Suryana, Shendi Susanti, Risa Suwandi, Deden Winda Suwendar Suwendar Tina Rostinawati