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All Journal JURNAL TEKNIK MESIN I-ECONOMICS: A Research Journal on Islamic Economics Jurnal Terapan Abdimas AL-FALAH : Journal of Islamic Economics NALAR: Jurnal Peradaban dan Pemikiran Islam Jurnal Kesehatan Tambusai AL-FALAH : Journal of Islamic Economics JOURNAL LA MEDIHEALTICO Jurnal Ekonomi dan Perbankan Syariah Jurnal Pengabdian Masyarakat Nusantara Jurnal Penelitian Inovatif Disclosure: Journal of Accounting and Finance COMSERVA: Jurnal Penelitian dan Pengabdian Masyarakat Buletin Kedokteran dan Kesehatan Prima International Journal of Health and Pharmaceutical (IJHP) Al-Istinbath: Jurnal Hukum Islam Journal of Pharmaceutical and Sciences.
Hendrianto Hendrianto, Hendrianto
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Evaluasi Formulasi Teh Celup dari Kombinasi Kulit Jeruk Manis (Citrus sinensis L.) dan Buah Ara (Ficus carica L.) sebagai Antibakteri terhadap Staphylococcus aureus Husni, M. Irgisyach Aqilla; Simat, Marcelina Oktavia Mayang Sari; Suhartomi, Suhartomi; Hendrianto, Hendrianto; Syarifah, Siti; Putri, Maulinda; Widyawati, Tri
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 4 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i4.1205

Abstract

The development of natural-based antibacterial agents is essential to reduce dependency on antibiotics and the risk of resistance. Sweet orange peel and fig fruit contain bioactive compounds with potential antibacterial effects. This study aimed to develop tea bag formulations made from sweet orange peel with the addition of fig fruit as an additive and to evaluate their in vitro antibacterial activity against Staphylococcus aureus. This experimental study employed two approaches, including disc diffusion and microdilution on several combination formulations of sweet orange peel and fig tea bags. The formulations consisted of F1 (1 g sweet orange peel and 1 g fig), F2 (1.5 g sweet orange peel and 0.5 g fig), and F3 (1.75 g sweet orange peel and 0.25 g fig). The disc diffusion assay showed that all formulations exhibited weak antibacterial activity against Staphylococcus aureus, producing inhibition zones of approximately 6–7 mm, except for F3 infusion, which demonstrated the widest inhibition zone with a mean diameter of about 8.21 mm (P-Value = 0.688). In the microdilution test, the MIC of F3 infusion was found to be 40 mg/mL, while the MBC was not detected at the tested concentrations. Overall, it can be concluded that the infusion of the tea bag formulation containing 1.75 g sweet orange peel and 0.25 g fig was the most promising combination; however, its antibacterial activity remained weak and was bacteriostatic rather than bactericidal.
Co-Authors Arhamni, Ade Artiani, Litri Diah Natalisa, Diah Dian Eka, Dian Elfalahy, Lutfi Elfalahy, Lutfy Erni Haryanti Fadhiyani, Zidya Ferdinand, Sahna Habiburrahman Habiburrahman, Habiburrahman Husni, M. Irgisyach Aqilla Ilhamiwati, Mega Ismoyo Haryanto Jansen, Jansen Khairul Umam Louis, Karen Lubis, Mutiara Salsabila Monica, Fina Mulan, Mulan Nadapdap, Faskanita Maristella Nasir, Nanat Fatah Noza Aflisia, Noza Nurcahyati, Dwi Ongko, Nicholas Xavier Patoni , Khairul Prasetiawan, Jauhari Putri, Maulinda Rahayu, Ika Gustin Rahimi, Armon Ratna Lestari Ridwan, A Hasan Silaban, Roma Asih Simat, Marcelina Oktavia Mayang Sari Sinaga, Lisa Kristiani Siti Syarifah Sopacua, Erwin Suhartomi Syahrial Dedi, Syahrial Tarigan, Setia Budi Toni Prahasto Tri Widyawati, Tri Ulmawandri, Juniko Yakin, Ikin Ainul