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Syarifin, Andi Noor Kholidha
Department Of Biochemistry, Faculty Of Medicine, Univeristas Halu Oleo, Kendari, Sulawesi Tenggara, Indonesia
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences

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Uji Diagnostik dengan Menggunakan Kriteria qSOFA dalam Mendiagnosis Awal Pasien Sepsis di Rumah Sakit Umum Bahteramas Provinsi Sulawesi Tenggara Nabila Shaddad; Agussalim Ali; Andi Noor Kholidha
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 8, No 2 (2021)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46496/medula.v8i2.20619

Abstract

ABSTRAKLatar Belakang: Sepsis merupakan salah satu masalah terbesar yang memerlukan perhatian, karena merupakan penyebab utama kematian dan penyakit kritis di seluruh dunia. Pada praktiknya, penilaian sepsis dengan skor SOFA membutuhkan pemeriksaan laboratorium, dan kriteria tersebut jarang digunakan di luar ruang rawat intensif. Mempertimbangkan hal tersebut, The Sepsis-3 Task Force memperkenalkan alat identifikasi yang lebih sederhana yaitu The Quick Sequential Organ Failure Assessment atau qSOFA. Penelitian ini bertujuan untuk mengetahui sensitivitas, spesifisitas, akurasi, nilai duga negatif, nilai duga positif kriteria qSOFA dalam mendiagnosis awal pasien sepsis di Rumah Sakit Umum Bahteramas Provinsi Sulawesi Tenggara. Metode: Penelitian ini adalah penelitian observasional deskriptif dengan rancangan penelitian cross sectional. Lokasi penelitian di ruang rekam Medik Rumah Sakit Umum Bahteramas. Sampel sebanyak 72 responden yang diambil menggunakan tehnik purposive sampling dengan menggunakan analisis data tabel 2x2. Hasil: Hasil penelitian didapatkan uji diagnostik kriteria qSOFA dalam mendiagnosis awal sepsis di RSU Bahteramas Provinsi Sulawesi Tenggara memiliki sensitivitas 55%, spesifisitas 88%, akurasi 72%, nilai duga positif 85% dan nilai duga negatif 66%.  Simpulan: Kriteria qSOFA memiliki sensitifitas kurang baik, namun spesifisitas yang baik dalam mendiagnosis awal pasien sepsis di RSU Bahteramas Provinsi Sulawesi Tenggara.Kata Kunci: Sepsis, qSOFA, Uji Diagnostik
Uji Aktivitas Ekstrak Etanol Daun Dadap Serep (Erythrina lithosperma Miq) sebagai Antibakteri terhadap Bakteri Salmonella typhi Andi Noor Kholidha; I Putu Wira Putra Suherman; Hartati Hartati
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 4, No 1 (2016)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (258.842 KB) | DOI: 10.46496/medula.v4i1.2555

Abstract

Dadap serep (Erythrina lithosperma Miq) is one of the plants that grow in Indonesia. Dadap serep leaves are commonly used as a traditional medicin. It can be used as an antimicrobial. This study aims to determine the inhibition of Dadap Serep (Erythrina lithosperma Miq) Leaf Extract  on the growth of the bacteria Salmonella typhi. The methods used in this research was an analytic experimental test. The samples of this study are Leaf Extract of Dadap Serep (Erythrina lithosperma Miq), which is divided into eight concentration, i.e. the concentration of 200,000 ppm, 100,000 ppm, 50,000 ppm, 25,000 ppm, 12,500 ppm, 6,250 ppm, 3,125 ppm, 1,560 ppm and two control i.e. a positive controls and a negative controls. Each test was repeated three times. Antibacterial activity test performed by disc diffusion method, wherein the diameter of each extract was determined and assessed their effectiveness inhibitory zone with chloramphenicol. Minimum Inhibitory Concentration (MIC) was determined by disc diffusion method togeth er with the inhibition test. We then measured at the lowest concentration of extract that they can inhibit the bacteria Salmonella typhiTop of FormBottom of Form. The results showed that the leaves of Dadap Serep (Erythrina lithosperma Miq) has antibacterial activity against growth of bacteria Salmonella typhi. MIC seen from the leaves of Dadap Serep is 50,000 ppm with inhibition zone diameter of 1.3 mm were formed. Diameter of clear zone is highest at a concentration of 200,000 ppm with inhibition zone diameter formed is 4.83 mm. Phytochemical test results on Leaf of Dadap Serep (Erythrina lithosperma Miq) retrieved alkaloids, flavonoids, tannins and saponins are positive.From this research it can be concluded that the extracts from dadap serep leaves (Erythrina lithosperma Miq) has antibacterial activity against growth of bacteria Salmonella typhi.Keywords: Dadap serep leaves (Erythrina lithosperma Miq), Salmonella typhi, Minimum inhibitory concentration (MIC), Antibacterial test
Pengaruh Ekstrak Bawang Putih Terhadap Kadar Serum Kreatinin Tikus Hipertensi Two Kidney One Clipp (Effect of Allium sativum Extract to Serum Creatinine of Two Kidney One Clipp Hypertension Rat) Sapto Raharjo; Gustavita Maria Bandong; Tien Tien; Andi Noor Kholidha Syarif; Agus Chahyadi; Pranita Aritrina
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 7, No 1 (2019)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (123.047 KB) | DOI: 10.46496/medula.v7i1.11831

Abstract

Background: Garlic (Allium sativum) has long been used both as a food and traditional medicine. Several studies have shown  potential of garlic (Allium sativum) as an antihypertensive. In previous in vitro study found that dipeptide on garlic extract after hydrolyzed by the enzyme papain have ACE inhibitory activity. Induction of hypertension with 2 Kidney One Clip (2K1C) methodcauses the kidneys lose their physiological functions. A.sativum is expected to ameliorate kidney function. This study aimed to analyze creatinine levels in rat induced by 2K1C. Method: These study was an in vivo study with Pre-Post Test Only Control group Design. Before treatment, 30 subjects induced hypertension by 2K1C method. Treatment was conducted for four weeks. The recent study was conducted on 36 Rattus norvegicus, Wistar strain were divided into 6 groups. Measurement of creatinine was conducted by spectrophotometry method. Result: The results showed that there were significant differences in creatinine levels between groups (p < 0.05) both in the pre-test and post-test. The normal group and hypertension group did not have significant differences in creatinine pre- and post-test levels (p > 0.05). A.sativum 75m/kgBB gave the best decrease in creatinine levels up to 1.75 mg/dL compared to the A.sativum 25mg/kgBB and A.sativum group 50 mg/kgBB. There were significant differences in creatinine levels A.sativum 75 mg/kgBB and captopril (p <0.05). Conclusion: There was significant differences in creatinine levels of hypertensive rats between groups and the most effective dose was 75 mg / kg. Keywords: A.sativum, hypertension, creatinine, 2K1C Latar Belakang: Bawang putih (Allium sativum) telah lama digunakan, baik sebagai bahan masakan maupun sebagai obat tradisional. Beberapa studi menunjukkan potensi bawang putih (A. sativum) sebagai antihipertensi. Pada penelitian sebelumnya secara in vitro ditemukan bahwa dipeptida pada ekstrak bawang putih setelah dihidrolisis dengan enzim papain memiliki aktivitas inhibisi terhadap ACE. Induksi hipertensi 2 Kidney One Clip (2K1C) menyebabkan ginjal kehilangan fungsi fisiologisnya. Pemberian A.sativum  diketahui mampu memperbaiki fungsi ginjal. Penelitian ini bertujuan untuk menganalisis kadar kreatinin pada tikus yang diinduksi 2K1C. Metode: Penelitian ini merupakan jenis penelitian in vivo dengan menggunakan rancangan Control Group Time Series Experimental. Parameter dalam penelitian ini adalah tekanan darah. Sebelum perlakuan, subjek diinduksi hipertensi dengan metode 2K1C. Perlakuan dimulai pada minggu ke-enam setelah induksi. Perlakuan berlangsung selama empat minggu. Subjek yang digunakan dalam penelitian adalah tikus putih (Rattus norvegicus, strain Wistar), sebanyak 36 ekor dibagi dalam 6 kelompok: normal/sehat (tidak diinduksi), hipertensi yang diberi kaptopril, hipertensi yang diberi ekstrak A.sativum 25mg/kgBB, hipertensi yang diberi ekstrak A. sativum 50mg/kgBB, hipertensi yang diberi ekstrak A. sativum 75mg/kgBB, dan hipertensi tanpa perlakuan. Pengukuran kreatinin dilakukan menggunakan metode spektrofotometri. Hasil: Analisis statistik menunjukkan terdapat perbedaan kadar kreatinin signifkan pada setiap kelompok (p < 0.05) baik pre-test maupun post-test. Kelompok normal dan hipertensi tidak memiliki perbedaan signifikan pada kadar kreatinin pre dan post-test (p > 0.05). Kelompok A. sativum 75m/kgBB menunjukkan penurunan kadar kreatinin yang sangat signifikan hingga 1.75 mg/dL dibanding kelompok  A. sativum 25mg/kgBB and A. sativum group 50 mg/kgBB. Terdapat perbedaan kadar kreatinin yang signifikan antara kelompok A. sativum 75 mg/kgBB dan captopril (p <0.05). Simpulan: Terdapat perbedaan kadar kreatinin yang signifikan antar kelompok dan penurunan kadar kreatinin terbaik yaitu pada dosis  75 mg / kg. Kata Kunci: A.sativum, hipertensi, kreatinin, 2K1C
Hubungan Kebiasaan Merokok, Stres dan Riwayat Keluarga dengan Kejadian Hipertensi Pada Masyarakat Usia Produktif di Puskesmas Katobu Kabupaten Muna Andi Noor Kholidha S; I Putu Sudayasa; Laode Anugrah Alhadzah Effendy
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 8, No 1 (2020)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46496/medula.v8i1.15028

Abstract

ABSTRAKLatar Belakang. Penyakit tidak menular (PTM) merupakan penyebab kematian di seluruh dunia dengan membunuh 36 juat jiwa pertahun. Salah satu penyebab kejadian penyakit tidak menular adalah hipertensi. Hipertensi adalah peningkatan tekanan darah sistolik lebih atau sama dengan 140 mmHg atau tekanan darah diastolik lebih atau sama dengan 90 mmHg. Berdasarkan umur, hipertensi paling banyak terjadi pada kelompok usia produktif sebesar 73.639 kasus. Pada tahun 2018 prevalensi hipertensi berdasarkan diagnosis dokter pada penduduk umur ≥18 tahun  menurut provinsi, Indonesia memiliki persentase 8,4%. Data profil kesehatan Sulawesi Tenggara tahun 2017 sebesar 11.265 kasus, kasus hipertensi di Puskemas Katobu sebanyak 539 kasus. Tujuan: Penelitian ini bertujuan Untuk mengetahui hubungan kebiasaan merokok, tingkat stres, dan riwayat keluarga hipertensi dengan kejadian hipertensi pada masyarakat usia produktif di Puskesmas Katobu, kabupaten Muna. Metode: Penelitian ini adalah penelitian analitik observasional dengan pendekatan case-control study. Kelompok kasus adalah penderita hipertensi berdasarkan diagnosis dokter puskesmas, kelompok kontrol adalah individu sehat yang tidak menderita hipertensi bertempat tinggal di wilayah kerja Puskesmas Katobu Kabupaten Muna. Jumlah sampel adalah 136 sampel terdiri dari 68 kelompok kasus dan 68 kelompok kontrol. Teknik pengambilan sampel menggunakan metode purposive sampling. Hasil: Hasil analisis bivariat kebiasaan merokok menunjukkan bahwa nilai p-value sebesar 0,000 dengan nilai OR 5.435. Hasil analisis pada stres menunjukkan bahwa nilai p-value sebesar 0,001, dengan nilai OR 3.429. Sedangkan analisis pada riwayat menunjukkan bahwa nilai p-value sebesar 0,000, dengan nilai OR 9.112. Simpulan: Simpulan dari penelitian ini adalah terdapat hubungan kebiasaan merokok, stres, dan riwayat keluarga dengan kejadian hipertensi pada masyarakat usia produktif di Puskesmas Katobu Kabupaten Muna. .Kata kunci. Hipertensi, merokok, riwayat keluarga hipertensi, stres, dan usia produktif.
Uji Antidiabetik Ekstrak Buah Pare (Momordica charantia L.) terhadap Penurunan Kadar Glukosa Darah pada Mencit yang Diinduksi Streptozotocin Parawansah Parawansah; Nuralifah Nuralifah; Andi Noor Kholidha
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 5, No 1 (2017)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (181.321 KB) | DOI: 10.46496/medula.v5i1.3889

Abstract

ABSTRACT Diabetes mellitus is a chronic disease in which the patient has excess glucose levels in the blood. Pare (Momordica charantia L.) is one of the plants that have efficacy in treating various diseases one of them is antidiabetes. Activity of active substances from the pare may play a role in lowering blood sugar levels. This research is done to know the effect of increasing concentration of pare extract to decrease blood glucose level in mice induced by streptozotocin.This study was experimental laboratory, the study was done by measured  the initial blood sugar level in mice, sugar content after induction of steptozotosin, and after administration of 100 mg / kgBW extract test, 250 mg / kgBW and 400 mg / kgBW with observation time for 7 days , as well as gave metformin suspension as a positive control.The results showed that the optimum value of antidiabetic activity of ethanol extract of pare fruit at a concentration of 400 mg / kgBW and had an average decrease of 122 mg / dl.Keywords: Antidiabetes, Momordica charantia L., Streptozotocin
Momordica charantia L. Fruit Fractions inhibit Malondialdehyde Level and Regenerate Hepatic Damage of Hyperglycemic Rats Parawansah Parawansah; I Putu Sudayasa; Andi Noor Kholidha Syarifin; Amirudin Eso; Nuralifah Nuralifah; Wa Ode Siti Rahayu Fathanah; Ferry Sandra
The Indonesian Biomedical Journal Vol 12, No 1 (2020)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v12i1.963

Abstract

BACKGROUND: Chronic hyperglycemia causes an increase of free radical production and in longterm, the hyperglycemia increases oxidative stress. Among medicinal plants, Momordica charantia L. fruit has been known to overcome hyperglycemia. However, role of M. charantia L. fruit on oxidative stress is not well understood. Therefore, current study was conducted to investigate the effect of M. charantia L. fruit extract on malondialdehyde (MDA) level and hepatic damage in hyperglicemic rat model.METHODS: Twenty five white rats (Rattus novergicus) were induced with Streptozotocin (STZ) and treated with/without glibenclamide, sodium carboxymethyl cellulose (Na-CMC), or M. charantia L. fruit ethanol/ethyl acetate/ n-hexane fraction. After the treatment, rat’s livers were collected and separated for histopathological examination and MDA analysis.RESULTS: The MDA level average of rats before the STZ induction was 1.37 μg/mL. MDA level average was markedly increased (23.85 μg/mL) in rats induced with STZ and treated with Na-CMC merely. The MDA level average of STZ-induced glibenclamide-treated rats was 3.12 μg/mL. Meanwhile, the MDA level averages of STZ-induced M. charantia L. fruit ethanol, ethyl acetate and n-hexane fractions-treated rats were 14.95, 8.98 and 5.37 μg/mL, respectively. The histopathology results of this study showed that adipocytes, dilated sinusoids and central vein thickening were mostly observed in STZ-induced Na-CMC-treated rats. Meanwhile, the STZ-induced ethanol/ethyl acetate/n-hexane fraction-treated rats did not exhibitthose expressions.CONCLUSION: M. charantia L. fruit fractions inhibit the MDA level average in liver tissue and regenerate hepatic damage of STZ-induced rats, especially the n-hexane fraction which could be a potential hepatic antioxidant and regenerative agent.KEYWORDS: Momordica charantia L., malondialdehyde, oxidative stress, hyperglycemia, diabetes mellitus
Hubungan Kadar High Density Lipoprotein (HDL) Dengan Kejadian Hipertensi Muhammad Syahril Rafsanjani; Asriati Asriati; Andi Noor Kholidha; La Ode Alifariki
Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan Vol 13, No 2 (2019): Jurnal Profesi Medika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran UPN Veteran Jakarta Kerja Sama KNPT

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33533/jpm.v13i2.1274

Abstract

Eventyally this study aims to determine the correlation between HDL levels as a risk factor of hypertension. This research used observational analytic design with cross sectional approach. The independent variable was total cholesterol levels and the dependent variable was hypertension. The research was located in Selabangga Village, Moramo District with the total sample of 57 samples based on the inclusion and exclusion criteria selected by the purposive sampling method. These data were obtained by using a measurement instrument of HDL level (lipids Pro) and blood pressure measurement devices (aneroid sphygmomanometer). The result of data was processed by Chi Square statistic test and Prevalence Odds Ratio (POR). The results of HDL research on hypertension found that from the 57 respondents, 34 respondents (56,9%) were hypertension and 25 respondents (43,9%) were hypertension whit HDL level at risk. Based on Chi-square statistical test, it was found that between HDL level and hypertension showed p value of 0.000 <α (0,05). While, the POR value of the HDL variable was 10,000 CI 95% 2,865-34,899. The conclusion of this study was the HDL level correlated as a risk factor for hypertension incidence.
PERBANDINGAN INDEKS MASSA TUBUH DAN TEKANAN DARAH PADA PEKERJA DI RUMAH POTONG HEWAN DAN KELOMPOK PETANI DI KOTA KENDARI Dionisius Excelsis Deo Sombolinggi; Andi Noor Kholidha Syarifin; Tien Tien; Laode Kardin; Pranita Aritrina; Arimaswati Arimaswati
NURSING UPDATE : Jurnal Ilmiah Ilmu Keperawatan P-ISSN : 2085-5931 e-ISSN : 2623-2871 Vol 13 No 1 (2022): MARET
Publisher : NHM PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36089/nu.v13i1.716

Abstract

Circadian rhythm is a natural clock in the human body. Night work can cause disturbances in the circadian rhythm. Circadian rhythm disturbances are known to be associated with an increase in psychosocial stress which can lead to an increase in blood pressure and BMI. This study aimed to compare BMI and blood pressure in day and night workers. This study was an analytical observational methods with a design case control. It was conducted in Labibia Village, Mandonga District and Anggoya Slaughterhouse, Kendari City in November 2021. The number of samples is 65 respondents, consist of 20 slaughterhouse workers and 45 farmer groups. Data analysis was carried out with the statistical test Chi-Square and then continued by determining the Odds Ratio (OR). The results showed that there was no significant difference between BMI of slaughterhouse workers and farmer groups (p = 0,096; POR 2,471 95% CI 0,840 – 7,265) and there was a significant difference between blood pressure of workers in abattoirs and farmer groups (p = 0,000 ; POR 52,250 ; 95% CI 6,293 – 433,842). There was no significant difference between BMI in slaughterhouse workers and farmer groups in Kendari city. There was a significant difference between blood pressure in abattoir workers and farmer groups in Kendari city in 2021 and night work was a risk factor for increasing blood pressure.
Pengaruh Extra Virgin Olive Oil (EVOO) Terhadap Kadar Lipid dan Indeks Massa Tubuh Wanita Obesitas Usia Produktif Ririn Afrianto; Tien Tien; Nina Indriyani; Tety Yuniarty Sudiro; Andi Noor Kholidha Syarifin; Haryati Haryati
Poltekita : Jurnal Ilmu Kesehatan Vol. 16 No. 2 (2022): August
Publisher : Poltekkes Kemenkes Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33860/jik.v16i2.1153

Abstract

Saat ini World Health Organization telah menetapkan obesitas sebagai epidemik global. Obesitas sering dihubungkan dengan kejadian dislipidemia termasuk penurunan kadar high density lipoprotein (HDL) dan peningkatan kadar low density lipoprotein (LDL). Hal ini juga sangat berkaitan dengan munculnya risiko penyakit jantung bahkan kematian. Pencarian bahan alami untuk memperbaiki status lipid pada penderita obesitas terus dilakukan, salah yang potensial dengan kandungan metabolitnya yang melimpah adalah minyak zaitun. Minyak zaitun mengandung asam lemak tak jenuh dan flavonoid yang dapat menurunkan lipotoksisitas dan ukuran sel lemak. Jenis minyak zaitun yang paling baik digunakan adalah extra virgin olive oil (EVOO), sehingga tujuan yang ingin dicapai dalam penelitian ini adalah untuk mengetahui perbedaan kadar lipid dan indeks masa tubuh (IMT) pada wanita obesitas usia produktif sebelum dan setelah pemberian EVOO. Penelitian ini merupakan studi quasi-eksperimental dengan pendekatan one group pretest-posttest without control group. EVOO dikonsumsi selama 3 minggu dengan dosis 30 mL/hari. Penelitian ini didapatkan rerata kadar HDL, LDL, dan IMT pada subjek sebelum dilakukan intervensi (pre-test) adalah 42,27 ± 4,5 mg/dL, 131,18 ± 16,9 mg/dL dan 28,4273 ± 3,3 kg/m2, sedangkan rerata kadar HDL, LDL, dan IMT pada subjek setelah dilakukan intervensi (post-test) EVOO adalah 44,09 ±4,6 mg/dL, 127,45 ± 29,4 mg/dL, dan 28,2164 ± 3,4 kg/m2. Analisis statistik menunjukkan tidak terdapat perbedaan yang bermakna antara kadar HDL, LDL, dan IMT sebelum dan setelah pemberian EVOO
Histopathological analysis of the liver in hypercholesterolemia rats treated with Dillenia serrata fruits Tien; Tri Wistya Utami; Pranita Aritrina; Laode Kardin; Sukurni; Andi Noor Kholidha Syarifin
Acta Biochimica Indonesiana Vol. 5 No. 2 (2022): Acta Biochimica Indonesiana
Publisher : Indonesian Society for Biochemistry and Molecular Biology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32889/actabioina.56

Abstract

Background: Dillenia serrata (locally known as singi) is a natural product with the potential to improve liver function in hypercholesterolemia, due to anticholesterol and antioxidant properties. Objective: This study aimed to investigate the effect of D. serrata on the histopathological features of rat livers induced by a high-fat diet. Methods: This study used a quasi-experimental in vivo with a post-test-only control group design. Rats were divided into four groups: normal, high-fat diet, as well as D. serrata, and simvastatin treatment. Hypercholesterolemia was induced by a high-fat diet for two weeks. Rat liver tissues were analyzed histologically using Hematoxylin-Eosin (HE) staining, and were observed under a light microscope at 40x magnification in five wide fields of view. Results: The high-fat diet group had the most adipose cells, while the D. serrata group had the least. Statistical analysis demonstrated a significant difference between the high-fat diet group and the other groups (p < 0.05). Interestingly, no significant difference between the D. serrata group and either the normal or simvastatin group (p > 0.05), suggesting the treatment of fruit may restore liver function comparable to normal and simvastatin group. Conclusion: The D. serrata fruit reduces the number of fat cells in the histopathology of rats induced with the high-fat diet.
Co-Authors Agus Chahyadi Agussalim Ali Ali, Agussalim Alifariki, La Ode Amirudin Eso Arimas wati Arimaswti Arimaswati Asranudin Asranudin, Asranudin Asriati Asriati Chahyadi, Agus Dionisius Excelsis Deo Sombolinggi Erik Veri Ramadani Eso, Amiruddin Fadhilah, Aulia Ferry Sandra Fifi Nirmala Gustavita Maria Bandong Hafizah, Indriah Hartati Hartati Haryati Haryati Haryati Haryati Holilah Holilah, Holilah I Putu Sudayasa I Putu Sudayasa I Putu Sudayasa I Putu Sudayasa I Putu Wira Putra Suherman Ikhlasul Amal Abdal Jamaluddin jamaluddin Junuda RAF Laode Anugrah Alhadzah Effendy Laode Kardin Laode Kardin Maharuni Nurqadriasti Djuddawi Muhammad Fathur Rahman Muhammad Syahril Rafsanjani Musyarrafah, Musyarrafah Nabila Shaddad Nina Indriyani Nuralifah Nuralifah, Nuralifah Parawansah Parawansah Parawansah Parawansah Parawansah Parawansah Parawansah Parawansah Pranita Aritrina Pranita Aritrina Pranita Aritrina Pranita Aritrina Pranita Aritrina Rahma Wati Rahmawati Rahmawati Rahmawati, Rahmawati Ririn Afrianto Sapto Raharjo Sapto Raharjo shaddad, Nabila Sjarif Subijakto, Sjarif Sukurni Tety Yuniarty Sudiro Ti en Tien Tien Tien Tien Tien Tien Tri Wistya Utami Wa Ode Siti Rahayu Fathanah Waode sitti asfiah udu, Waode sitti asfiah