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All Journal Abdimasku : Jurnal Pengabdian Masyarakat Open Access Health Scientific Journal Jurnal Pengabdian Kepada Masyarakat: Kesehatan (JPKMK) Riset Informasi Kesehatan PCJN Pharmaceutical and Clinical Journal of Nusantara Strada Jurnal Ilmiah Kesehatan (SJIK) Strada Journal of Pharmacy APMa Jurnal Pengabdian Masyarakat
Putri, Luluk Aniqoh Meliana
Universitas STRADA Indonesia
Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Effectiveness and Physical Quality Test of Ashitaba Leaf Extract Exfoliating Toner against Staphylococcus epidermidis and Propionibacterium acnes Luluk Aniqoh Meliana Putri; Devita Riafinola Andaririt
Open Access Health Scientific Journal Vol. 7 No. 1 (2026): February 2026
Publisher : Griya Eka Sejahtera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55700/oahsj.v7i1.134

Abstract

Background: Acne (acne vulgaris) is a chronic inflammatory skin disease with a complex pathogenesis, involving the sebaceous glands and excessive colonization of acne-causing bacteria. In the modern era, the trend of using natural cosmetics is gaining momentum, not only in Indonesia but also globally. An example of a plant with great potential is Ashitaba. Ashitaba leaves have antibacterial. This study aimed to observe the physical quality test and antibacterial test of ashitaba leaf extract toner against Staphylococcus epidermidis and Propionibacterium acnes bacteria.Methods: The design in this study is an experimental method, physical quality tests include, Organoleptic tests are carried out visually, the components evaluated are the smell, shape, color and texture of the preparation, pH test and viscosity test.  analysis of data from the physical quality test of the Ashitaba leaf extract facial toner, the physical characteristics of the preparation, including organoleptic, homogeneity, viscosity, and pH, of all three formulas met the parameters.Results: The toner tested against Staphylococcus epidermidis and Propionibacterium acnes bacteria had the largest inhibition zone, namely with an extract concentration of 20%.Conclusion: The toner tested against Staphylococcus epidermidis bacteria with a 20% extract had the largest inhibition zone of 27.6 mm, while Propionibacterium acnes bacteria with a 20% extract had the largest inhibition zone of 27.9 mm
Anti-Acne Activity Evaluation Of Cyperus rotundus L. Rhizome Fraction Gel Against Staphylococcus aureus And Propionibacterium acnes Musdalifah Qadariah; Juvita Herdianty; Luluk Aniqoh Meliana Putri; Ardhi Broto Sumanto
Strada Journal of Pharmacy Vol. 7 No. 2 (2025): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v7i2.203

Abstract

Acne is an inflammatory skin condition often caused by bacteria such as Propionibacterium acnes and Staphylococcus aureus. The increasing incidence of antibiotic resistance encourages the search for alternatives from natural ingredients. Nut grass rhizome (Cyperus rotundus L.) is known to have antibacterial compounds. This study aimed to formulate a gel from the fractions of nut grass rhizome, test its activity against acne-causing bacteria, and identify the most potent fraction. This study employed a laboratory experimental design. The nut grass rhizome was extracted with 70% ethanol and then fractionated by liquid-liquid partitioning using n-hexane, ethyl acetate, and water as solvents. Each fraction was formulated into a gel at a 5% concentration, and its antibacterial activity was tested using the well diffusion method. All gel formulas met the physical quality evaluation requirements. The ethyl acetate fraction (F2) exhibited the strongest antibacterial activity, with an average inhibition zone of 19.48 ± 0.99 mm (moderate category) against Staphylococcus aureus and 25.86 ± 0.65 mm (strong category) against Propionibacterium acnes. The nut grass rhizome fraction gel preparation possesses anti-acne activity. The ethyl acetate fraction proved to be the most potent, showing efficacy against Propionibacterium acnes (inhibition zone 25.86 mm) that was statistically equivalent to the positive control (p = 0.767).
Co-Authors Adjie Wahyu Pradana Amalia Eka Putri Anggi Restyana Ardhi Broto Sumanto Ardhi Broto Sumanto Ardhi Broto Sumanto Arif Wijayanto Arif Wijayanto Chinthia Devientasari Chinthia Devientasari Dabyt Faizin Firzatullah Devientasari, Chinthia Devita Riafinola Ismi Rahmawati Ivan Junius Mesak Ivan Junius Mesak Ivan Junius Mesak Juvita Herdianty Juvita Herdianty Juvita Herdianty Lambertini, Imelda Lutpiani, Elpi Musdalifah Qadariah Opstaria saptarini Purnaningtyas, Sri Rahayu Dwi Qadariah, Musdalifah Saifullah Al Fahmi Selly Septi Fandinata Sri Rahayu Dwi Purnaningtyas Varel Tsania Faza Yahya Febrianto