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All Journal CAKRA KIMIA (Indonesian E-Journal of Applied Chemistry) Jurnal Veteriner JURNAL PETERNAKAN Indonesian Journal of Pharmaceutical Science and Technology Pharmascience Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) As-syifaa Jurnal Farmasi Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal farmasi UIN Alauddin Makassar Jurnal Agrisistem Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Parapemikir Jurnal Ilmiah Farmasi Kartika : Jurnal Ilmiah Farmasi
Abdul Wahid Jamaluddin
Universitas Hasanuddin
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Electrical & Electronics Engineering Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Physics Public Health Social Sciences Veterinary

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Journal : Pharmascience

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Perbandingan Pemberian Madu Lokal Bunga Cengkeh (Syzygium aromaticum) dan Madu Impor Bunga Manuka (Leptospermum scoparium) Secara Topikal Terhadap Penyembuhan Luka Sayat Pada Mencit Putih (Mus musculus) Nikita Tenritojang Mustafa; Dini Kurnia Ikliptikawati; Abdul Wahid Jamaluddin
Jurnal Pharmascience Vol 6, No 2 (2019): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v6i2.7347

Abstract

ABSTRAK Luka merupakan trauma fisik mengakibatkan kulit terbuka. Luka merupakan jalur masuk bagi mikroorganisme dari luar penyebab infeksi. Dahulu madu dimanfaatkan untuk mengobati luka bakar dan luka sayat. Madu memiliki keunggulan yakni memiliki hidrogen peroksida, eugenol dan methylglyoxal yang merupakan antibiotik yang unggul. Penelitian ini dilakukan dengan uji ekperimental. Hewan coba dibagi dalam 4 kelompok. Setiap kelompok diberikan perlakukan antara lain: dengan pemberian madu lokal, madu impor, dan salep povidone iodine (kontrol positif), dan kelompok kontrol negatif tanpa perlakuan. Dilanjutkan pemantauan dan pencatatan untuk proses penyembuhan tiap kelompok. Hal ini diukur dengan indikator antara lain: luas luka, kelembaban luka, warna, serta perubahan keropeng. Pada penelitian ini ditemukan bahwa dengan pemberian madu mempercepat proses penyembuhan luka dibandingkan dengan pemberian air dan povidone iodine (p<0,05). Selain itu ditemukan madu lokal memberikan efek penyembuhan luka yang lebih cepat dibandingkan madu impor. Pemberian madu memberikan efek yang lebih baik terhadap penyembuhan luka. Dibandingkan dengan pemberian salep Povidone iodine dan tanpa perlakuan.Kata kunci : Madu Bunga Cengkeh, Madu Bunga Manuka, Waktu penyebuhan, Warna Luka, Kelembaban. ABSTRACT Wound is a physical trauma causes discontinuity, Leads physiological dysfunction. Wound is an entry point for microorganisms from outside as source of infection. In the past, honey was used to treat burns and cuts. Honey is a natural ingredient as a moist wound-dressings. Besides that, honey contain hydrogen peroxide, eugenol, and methylglyoxal which is a superior antibiotic. This research was carried out by experimental test. The experimental animals were divided into 4 groups, each group consisted of 6 animals. Each group is treated, among others; by giving local honey, imported honey, povidone iodine (positive control), and negative control group without a treatment. Continued monitoring and recording for the healing process of each group. Statistical analysis is performed by calculation of frequency distribution and Independent-t, Anova, and regression analysis to determine the relationship between each variable. Statistical test results are significant if the value of p <0.05. This research found that addition of honeyaccelerated the wound healing process compared to the administration of water and povidone iodine (p <0.05). This is measured by indicators including; wide wounds, moisture wounds, colour change, and scab changes. By giving honey the perfect wound healing process begins on the 11th day until the 13th day. Besides that, local honey is found to provide healing effects that are faster than imported honey. Giving honey provides a better effect on wound healing. compared with Povidone iodine and without a treatment Keywords: Clove Flower Honey, Manuka Flower Honey, Time of Wasting, Colour of Wound, Moisture
Co-Authors A. Ika H.A. Imran A.B Adikurniawan, Yuko Mulyono Adriyani Ris Adryani Ris Ainun, Hasri Amir, Muhammad Nur Anak Agung Putu Joni Wahyuda Andi M. S. Apada Andi Magfira Satya Apada Andi Muhammad Taufan Apada, Andi Magfira Satya Aprilia, Eka Arifah, Sitti Ayu Lestari Azzahrah, Nur Faatimah Baso Yusuf Bone Ramadhan Carisma Sumule Ciputra, Lyvia Angeline Dwi Kesuma Sari Febyana, Andi Fedri Rell Handayani, Nur Atikah Hastang, Hastang Hikmah, Hikma Hosea, Cindy Trie Permatasari Ikliptikawati, Dini Kurnia Imran A.B, A. Ika H.A. Jamilah, Ainun Kadek Evi D.P. Dewi Lucia Musimin Lucia Muslimin M. Natsir Djide Magfira Satya Apada Mapparenta, Bulan Allu Mappiara, Muhammad Afiq S. Minarfa, Tiara S Muhammad Alamsyah Muhammad F. Mursalim Muhammad Fadhil Shalih Muhammad Fadhlullah Mursalim Muhammad Fadhlullah Mursalim Muhammad Fadhlullah Mursalim Muhammad Muflih Nur Muhammad Natsir Djide Mursalim, Muhammad Fadhlullah Musdalifah Musdalifah Muthia Milasari Nahariah Nahariah, Nahariah Nikita Tenritojang Mustafa Nur Ilmi Rahmiati Nur Sriani Rezki Nurmauliah Syaharuddin Nurul Fajriani M Purba, Fika Yuliza Rasdiyanah Rasdyanah Rasdyanah Rian Hari Suharto Ris, Adryani Risyani, Risna Rizal, Yuki Nurindar RR. Ella Evrita Hestiandari Sarah, Ruhil Aziz Siti Maryam Sitti Arifah Suharto, Rian Hari Suryadi Pappa Suryadi Pappa Syahbar, Lutfiah Kurnia Wa Ode Santa Monica waode santa monica WAODE SANTA MONICA Yuko Mulyono Adikurniawan Zainal Abidin Kholilullah Zainal Abidin Kholilullah Zulfikri Mustakdir