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Mar’atun Jannah, Imrawati, Muzakkir Baitz,
STIFA Makassar
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Education Electrical & Electronics Engineering Energy Engineering Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health

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VARIASI CAIRAN PENYARI EKSTRAK DAUN PUCUK MERAH (Syzygium myrtifolium Walp.) TERHADAP BIOAKTIVITAS BAKTERI Propionibacterium acne Imrawati, Imrawati; Kursia, Sukriani; Desiana, Desiana
JNSTA ADPERTISI JOURNAL Vol. 3 No. 2 (2023): Juli 2023
Publisher : Aliansi Dosen Perguruan Tinggi Swasta Indonesia (Adpertisi)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62728/jnsta.v3i2.455

Abstract

Acne is a skin disease that can block the appearance of the face, neck and back of the body. Acne occurs because the liquid sebum fat is converted by the bacteria Propionibacterium acne to become denser so that it is easy to clog the skin pores. The purpose of this study was to determine the antibacterial activity of red shoots (Syzygium myrtifolium Walp.) with a variety of filter fluids against Propionibacterium acnes bacteria. The sampling technique was carried out by picking the red leaves. The results showed that the bioactivity as antibacterial of ethanol extract, ethyl acetate, and n-hexane of red shoots leaves contained tannins in the ethanol extract, flavonoids, alkaloids, tannins, saponins and steroids in the ethyl acetate extract and alkaloids, tannins, saponins and steroids in the extract. n-hexane. testing the antibacterial activity of each extract with a concentration of % obtained the great value on the n-hexane extract with an inhibitory power value of 14.5 mm with a strong category, and the results of statistical processing SPSS non-parametric method with further tests from the Kruskal Wallis Test it was found that the difference between each extract with the great value was found in the n-hexane extract, namely 14.21.
Edukasi Pencegahan Penyakit Skabies Melalui Peer Educator Di Sekolah Enterpreneur Tahfidz Kekasih Al-Aqsha, Gowa, Sulawesi Selatan Muslimin, Lukman; Marwati, Marwati; Mus, Suwahyuni; Rosyid, Sujud Z; Irwana, Rina; Djamaluddin, Suci F; Khairi, Nur; Indrisari, Maulita; Nursamsiar, Nursamsiar; Megawati, Megawati; Imrawati, Imrawati; Nur, Syamsu; Sami, Fitriyanti; Amin, Astuti; Paluseri, Andi
Jurnal Pengabdian Kefarmasian Vol 4, No 2 (2023): JURNAL PENGABDIAN KEFARMASIAN
Publisher : Jurusan Farmasi Politeknik Kesehatan Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32382/jpk.v4i2.3421

Abstract

Scabies Prevention Through Peer Educators At The Entrepreneur School Of Tahfidz Kekasih Al-Aqsha, Gowa, South SulawesiBased on a survey that was carried out, it was found that there were incidents of head lice and scabies infections at the Tahfidz Kekasih Al-Aqsa Entrepreneurial School, in Pattallassang, Kab. Gowa, South Sulawesi. This shows that the student's knowledge of this disease is still low. So it is necessary to carry out outreach to increase students' knowledge of the dangers of scabies and its treatment. 45 students and 5 teachers attended this counseling. The methods used in this service are lecture, question and answer, and scabies examination. The presentation of material about scabies was carried out using PowerPoint media, after which the material continued with a question-and-answer session. At the end of the activity, a health examination was carried out to identify and provide treatment to students and teachers who suffered from scabies. The results of the counseling showed that 2 students were suffering from scabies. The counseling was considered successful because the students answered all the questions (100%).Keywords: Counseling, Peer Education, Scabies Berdasarkan survei yang telah dilakukan ditemukan adanya kejadian infeksi kutu rambut dan skabies (kudis) di Sekolah Enterpreneur Tahfidz Kekasih Al-Aqsha, di Pattallassang, Kab. Gowa, Sulawesi Selatan. Hal ini menunjukkan masih rendahnya pengetahuan para santri terhadap penyakit tersebut. Maka perlu dilakukan sosialisasi untuk meningkatkan pengetahuan santri terhadap bahaya penyakit skabies serta pengobatannya. Penyuluhan ini diikuti oleh 45 orang santri dan 5 orang guru. Metode yang digunakan dalam pengabdian ini adalah metode ceramah, tanya jawab, dan pemeriksaan skabies. Pemaparan materi tentang skabies dilakukan menggunakan media PowerPoint, setelah pemaparan materi dilanjutkan dengan sesi tanya jawab. Di akhir kegiatan, dilakukan pemeriksaan kesehatan untuk mengetahui dan memberikan pengobatan kepada santri maupun guru yang menderita skabies. Hasil penyuluhan menunjukkan bahwa ada 2 orang santri yang menderita skabies. Penyuluhan dinilai berhasil karena semua pertanyaan yang diberikan berhasil dijawab oleh santri (100%).Kata kunci : Penyuluhan, Peer Education, Skabies
Identifikasi dan Penetapan Kadar Flavonoid Ekstrak Etil Asetat Daun Mimba (Azadiractha indica A. Juss) Metode Spektrofotometri UV- Vis Utami, Yuri Pratiwi; Imrawati, Imrawati; Mustarin, Rahmah; Mus, Suwahyuni; Jariah, Ainun
Journal of Experimental and Clinical Pharmacy (JECP) Vol 4, No 2 (2024): August 2024
Publisher : Poltekkes Kemenkes Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52365/jecp.v4i2.1049

Abstract

Flavonoid terdiri dari 15 molekul yang tersusun dalam susunan C6-C3-C6 yang merupakan senyawa polifenol. Senyawa ini berbentuk kerangka karbon dan terurai menjadi dua set: C6 dan C3. Daun mimba (Azadiractha indica A. Juss) mengandung flavonoid yang memiliki sifat antioksidan, antibakteri, dan antikanker. Penelitian ini bertujuan untuk mengidentifikasi kelompok senyawa dalam daun mimba (Azadirachta indica A. Juss) dan menentukan kadar flavonoidnya. Ekstraksi dilakukan menggunakan teknik maserasi dengan pelarut etil asetat untuk mendapatkan ekstrak yang kemudian diuji melalui skrining fitokimia. Pengukuran kadar flavonoid dilakukan dengan metode spektrofotometri UV-Vis. Dari hasil ekstraksi, diperoleh rendemen ekstrak sebesar 5,83%. Hasil skrining fitokimia menunjukkan adanya kandungan flavonoid dan alkaloid. Kadar flavonoid ditentukan menggunakan kuersetin sebagai standar pembanding, dengan persamaan garis y = 0,0739x + 0,0776. Kesimpulannya, ekstrak etil asetat mengandung flavonoid dengan kadar 1,183 ± 0,018%.Flavonoids consist of 15 molecules arranged in a C6-C3-C6 configuration, which are polyphenolic compounds. These compounds form a carbon framework and are divided into two sets: C6 and C3. Neem leaves (Azadirachta indica A. Juss) contain flavonoids that have antioxidant, antibacterial, and anticancer properties. This study aims to identify the group of compounds in neem leaves (Azadirachta indica A. Juss) and determine their flavonoid content. Extraction was carried out using the maceration technique with ethyl acetate as a solvent to obtain an extract that was then tested through phytochemical screening. Flavonoid content was measured using the UV-Vis spectrophotometric method. The extraction process yielded an extract with a percentage of 5.83%. Phytochemical screening results indicated the presence of flavonoids and alkaloids. The flavonoid content was determined using quercetin as a reference standard, with the equation y = 0.0739x + 0.0776. In conclusion, the ethyl acetate extract contains flavonoids with a concentration of 1.183 ± 0.018%.
Sosialisasi Pelaksanaan Pengelolaan Obat Di Puskesmas Mamajang Aripa, Lusyana; Betan, Abu Bakar; Zaenal, Zaenal; Wahyuni, Sri; Utami, Yuri Pratiwi; Imrawati, Imrawati
Sahabat Sosial: Jurnal Pengabdian Masyarakat Vol. 1 No. 4 (2023): Sahabat Sosial: Jurnal Pengabdian Masyarakat (September)
Publisher : Asosiasi Guru dan Dosen Seluruh Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59585/sosisabdimas.v1i4.171

Abstract

Drug management is a pharmaceutical service activity that starts from planning, procurement, distribution, use and disposal of drugs. The aim is to ensure the continuity and availability of efficient, effective and rational medicines, increase the competency of pharmaceutical staff, create a management information system and implement service quality control and implementation relationships in drug management at the Mamajang Community Health Center, Mamajang District, Makassar City. Collection was carried out through in-depth interview techniques and direct observation. The results of drug planning at the Mamajang Community Health Center are in accordance with the drug management guidelines which are seen based on needs at the Community Health Center. Requests for drugs are in accordance with the procedures for procuring/requesting drugs from the Health Service via LPLPO to the District Pharmacy Warehouse (GFK). The distribution of medicines at the Mamajang Community Health Center is not in accordance with the drug management guidelines from GFK and is not in accordance with the needs at the Community Health Center, due to the lack of budget from the APBD which is channeled through the City Health Service. The conclusion is that the planning and use of drugs is in accordance with procedures, while the distribution of drugs is not in accordance with drug management guidelines because the APBD budget is not channeled through the Health Service. So it is hoped that when distributing medicines from the Makassar City Health Service or (GFK) they should pay attention to the procurement/request for medicines based on the LPLPO. The high population ratio in Pamenang, Tanjung, and Gangga Districts compared to existing health facilities and personnel is a very principal problem related to health education for the community, including information about health. One of them is about the correct procedures for obtaining, using, storing and managing medicines which includes how to use special medicines. The aim of this socialization is to educate human resources at the Mamajang Community Health Center. Socialization of this program is carried out through the delivery of material, discussions, questions and answers, demonstrations by pharmacists. The participants happened to be human resources at the Community Health Center who were very enthusiastic about this program because of the participants' activeness in asking and answering questions about drug management.
Pendidikan Kesehatan, Pemeriksaan dan Deteksi Dini Pencegahan Penyakit Tidak Menular melalui Kegiatan Olah Raga Fisik di Wilayah Kerja Puskesmas Tamalanrea Makassar Hilal, Achmad; Rachman, Arif; Hardianti, Hardianti; Sari, Lely Meriaya; Imrawati, Imrawati; Utami, Yuri Pratiwi
Sahabat Sosial: Jurnal Pengabdian Masyarakat Vol. 2 No. 4 (2024): Sahabat Sosial: Jurnal Pengabdian Masyarakat (September)
Publisher : Asosiasi Guru dan Dosen Seluruh Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59585/sosisabdimas.v2i4.417

Abstract

Non-communicable diseases are a group of diseases that cannot be transmitted, but non-communicable diseases are the main cause of death in 68% of the world. In fact, currently the incidence of non-communicable diseases has reached ±38 million sufferers and is predicted to continue to increase to reach 52 million people in 2030. This activity aims to increase people's knowledge and healthy living behavior regarding non-communicable diseases, empower health cadres and community health centers to carry out early detection of non-communicable diseases through anthropometric measurements, and reduce the prevalence and complications of non-communicable diseases in the community. The benefits of this activity are providing accurate and easy to understand information about non-communicable diseases through leaflets, improving people's health and quality of life, and supporting government programs in preventing and controlling non-communicable diseases. The methods used in this activity are health checks, nutritional counseling and community service demonstrations through training and counseling activities with Health Education, Examination and Early Detection, Prevention of Non-Communicable Diseases through Physical Sports Activities in the Tamalanrea Makassar Health Center Working Area. The results of the education were assessed by completing a pre-post education questionnaire and a significant increase in scores was obtained, meaning that the education carried out had increased the knowledge of women of childbearing age and the elderly regarding non-communicable diseases and their prevention.
Penetapan Sifat Fisikokimia Ekstrak Etanol Daun Mimba (Azadiractha indica A. Juss) : Penelitian Eksperimen Berskala Laboratorium Pratiwi Utami, Yuri; Imrawati, Imrawati; Jariah, Ainun; Mustarin, Rahmah; Bone, Mahfuzun; Bachri, Nurjannah
Health Information : Jurnal Penelitian Vol 16 No 3 (2024): September-Desember
Publisher : Poltekkes Kemenkes Kendari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36990/hijp.v16i3.1298

Abstract

Daun mimba (Azadirachta indica A. Juss) banyak digunakan sebagai obat tradisional yaitu untuk mengobati malaria, kencing manis, diare, penurun panas, dan antitukak lambung. Aktivitas suatu ekstrak dapat dipengaruhi oleh senyawa aktif yang terkandung di dalamnya yang bergantung pada sifat fisikokimia dari ekstrak. Penelitian ini bertujuan untuk menentukan sifat fisikokimia ekstrak etanol daun mimba (A. indica A. Juss.). Penelitian bersifat experimental berskala laboratorium yang dimulai dengan sampel diproses hingga menjadi simplisia; kemudian, simplisia diekstraksi melalui metode maserasi dengan pelarut etanol 70%. Penetapan sifat fisikokimia meliputi beberapa parameter yaitu rendemen, organoleptik, kadar senyawa terlarut, penetapan kadar senyawa terlarut, skrining fitokimia, dan penetapan kadar flavonoid total. Hasil penelitian menunjukkan bahwa ekstrak etanol menghasilkan sifat fisikokimia yaitu rendemen ekstrak 19,438 %, organoleptik ekstrak (bentuk (kental); warna (hijau kehitaman); bau (khas); dan rasa (pahit)), penetapan kadar senyawa terlarut (senyawa terlarut air (62.5%); senyawa terlarut pada etanol (71.3%)), skrining fitokimia mengandung (alkaloid, flavonoid, saponin, steroid dan tannin), dan kadar flavonoid total ekstrak yaitu 1.829%.  Dapat disimpulkan bahwa ekstrak etanol daun mimba (A. indica A. Juss.) dapat ditetapkan sifatnya secara fisikokimia dengan beberapa parameter yang telah diuji untuk mengetahui karakteristiknya sehingga disarankan ekstrak ini dapat dikembangkan dalam bentuk sediaan obat bahan alam.
Implementasi Fungsi Sebagai Apoteker Dalam Terapi Pengobatan Swamedikasi Diare Pada Anak Di Sulawesi Selatan Utami, Yuri Pratiwi; Mustarin, Rahmah; Humang, Rezki Ihsan; Imrawati, Imrawati; Amody, Zahira
Sahabat Sosial: Jurnal Pengabdian Masyarakat Vol. 3 No. 3 (2025): Sahabat Sosial: Jurnal Pengabdian Masyarakat (Juni)
Publisher : Asosiasi Guru dan Dosen Seluruh Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59585/sosisabdimas.v3i3.688

Abstract

Diarrhea is one of the main causes of morbidity and mortality in children, especially in areas with limited access to health services. Self-medication is the main alternative for some people, but is often done without adequate understanding. This community service activity aims to improve parents' understanding of self-medication for diarrhea in children and implement the role of pharmacists in providing education and monitoring rational drug use. Activities are carried out in several areas in South Sulawesi through counseling, training, and individual consultations. The results of the activity show an increase in knowledge and more appropriate behavior in the use of antidiarrheal drugs. The implementation of the role of pharmacists has proven effective in encouraging safe and rational self-medication in the community.
Profile of Pulmonary Tuberculosis Treatment at Kaluku Bodoa Health Center, Makassar City, 2023 Imrawati, Imrawati; Utami, Yuri Pratiwi; Mustarin, Rahmah; Jariah, Ainun; Humang, Rezki Ihsan; Amody, Zahira; S, St. Mujahida
International Journal of Health Sciences Vol. 3 No. 2 (2025): IJHS : International Journal of Health Sciences
Publisher : Asosiasi Guru dan Dosen Seluruh Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59585/ijhs.v3i2.752

Abstract

Global TB Report 2022 recorded more than 700 thousand TB cases. This figure is the highest since TB became a National Priority Program. In Indonesia, the highest number of TB cases is found in the productive age group, especially those aged 45 to 54 years. This study aims to determine the profile of pulmonary tuberculosis treatment at the Kaluku Bodoa Health Center. The research design used is a non-experimental study with data collection conducted retrospectively using medical records, including individual characteristics (age, gender, education, occupation), patient type, type of Directly Observed Treatment (DOT) supervisor, and treatment category. Based on the research conducted at the Kaluku Bodoa Health Center, data showed a total of 201 pulmonary tuberculosis patients. In terms of individual characteristics, there were 44 patients aged 46-55 years, 123 male patients, the majority of whom had a primary education level (97 patients), and most of the patients were working (174 patients). Based on patient type, there were more new patients, totaling 177. All patients had a family DOT supervisor, totaling 201 patients. The treatment category used is category 1 for 197 patients.
Ekstrak Daun Kenikir (Cosmos caudatus Kunth.) dengan Variasi Metode Ekstraksi sebagai Penangkal Radikal Bebas ABTS: Kenikir Leaf Extract (Cosmos caudatus Kunth.) with Variations in Extraction Methods as an Antidote to Free Radicals ABTS Utami, Yuri Pratiwi; Mubarak, Fhahri; Imrawati, Imrawati; Jariah, Ainun; Mangosa, Grace Pretty
Jurnal Sains dan Kesehatan Vol. 7 No. 4 (2025): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v7i4.2448

Abstract

Cosmos caudatus Kunth. is a plant that has secondary metabolites that are antioxidant. This study aims to determine the antioxidant activity of the ethanol extract of kenikir leaves which was extracted using a variety of extraction methods with the radical antidote ABTS. Samples of kenikir leaves were processed until they became simple and then extracted using three methods, namely maceration, percolation and digestion. The extracts obtained were subjected to phytochemical screening and the antioxidant activity of the ethanol extract of kenikir leaves was tested using UV-Vis spectrophotometry using the ABTS method (2,2 azinobis (3-ethylbenzothyiazoline-6-sulfonic acid). In testing the antioxidant activity of kenikir leaves, the results showed that the extract using the maceration method had antioxidant activity with an IC50 of 166,962 µg/mL, the extract using the digestion method IC50 84,117 µg/mL and the ethanol percolation extract of kenikir leaves 113,901 µg/mL, with quarcetin. as a positive control with an IC50 of 90.566 µg/mL. This study concluded that extracts with a variety of extraction methods had antioxidant activity, namely digestion (strong), percolation (medium), and maceration (weak). Keywords:          Cosmos caudatus Kunth., extraction, antioxidant, ABTS   Abstrak Kenikir (Cosmos caudatus Kunth.) merupakan tanaman yang memiliki metabolit sekunder yang bersifat antioksidan. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan dari ekstrak etanol daun kenikir yang diekstraksi menggunakan variasi metode ekstraksi dengan penangkal radikal ABTS. Sampel daun kenikir diolah hingga menjadi simplisia kemudian dilakukan ekstraksi dengan tiga metode yaitu maserasi, perkolasi dan digesti. Ekstrak yang diperoleh dilakukan skrining fitokimia dan pengujian aktivitas antioksidan ekstrak etanol daun kenikir dilakukan menggunakan spektrofotometri UV-Vis dengan menggunakan metode ABTS (2,2 azinobis (3-ethylbenzothyiazoline-6-sulfonic acid). Pengujian aktivitas antioksidan daun kenikir diperoleh hasil bahwa ekstrak dengan metode maserasi memiliki aktivitas antioksidan dengan IC50 166,962 µg/mL, ekstrak metode digesti IC50 84,117 µg/mL dan ekstrak perkolasi etanol daun kenikir 113,901 µg/mL, dengan kuarsetin sebagai kontrol positif dengan IC50 90,566 µg/mL. Penelitian ini menyimpulkan bahwa ekstrak dengan variasi metode ekstraksi memiliki aktivitas antioksidan yaitu digesti (kuat), perkolasi (sedang), dan maserasi (lemah). Kata Kunci:         Kenikir,  eksraksi, antioksidan, ABTS
Antioxidant Activity Of Leilem Leaf Extract Fractions Clerodendrum minahassae Teijsm. and Binn. Using The DPPH Method (2,2-Diphenyl-1-Picrylhydrazil) Imrawati, Imrawati; Utami, Yuri Pratiwi; Hardianto, Hardianto
International Journal of Health Sciences Vol. 1 No. 4 (2023): IJHS : International Journal of Health Sciences
Publisher : Asosiasi Guru dan Dosen Seluruh Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59585/ijhs.v1i4.220

Abstract

Clerodendrum minahassae Teijsm. and Binn plant is included in the Clerodendrum genus which contains chemicals such as alkaloids, flavonoids, phenols, tannins and steroids which have an important role in the development of medicine, including as antioxidants, anti-inflammatory, anti-diabetic and antibacterial. This study aims to determine the antioxidant activity of leilem leaf fractions using the DPPH method. Leilem leaves were extracted using the maceration method using 70% ethanol, then partitioned using the liquid-liquid extraction method using three different solvents, namely n-hexane, ethyl acetate and water. The fraction of the partition was then tested for antioxidant activity using the DPPH method and its absorbance was measured using a UV-VIS spectrophotometer with a wavelength of 515 nm. The research results showed that the n-hexane fraction had an IC50 value of 185.704 ppm, the ethyl acetate fraction had an IC50 value of 105.357 ppm and the water fraction had an IC50 value of 549.258 ppm with the IC50 value of the quarcetin comparison being 8.86 ppm. It can be concluded that the highest antioxidant activity is found in the ethyl acetate fraction, which is included in the moderate antioxidant category.
Co-Authors Abubakar Betan Agiel, Fadillah Maryam Bau Ainun Jariah Amody, Zahira Arif Rachman Aripa, Lusyana Astri, Andi Astri Sri Nurul Fardila Astuti Amin Bone, Mahfuzun Desiana Desiana, Desiana Djamaluddin, Suci F Fhahri Mubarak Hardianti Hardianti, Hardianti HARDIANTO - Hilal, Achmad Humang, Rezki Ihsan Irwana, Rina Khairi, Nur Mangosa, Grace Pretty Maria Ulfa Maulita Indrisari, Maulita Megawati - Mus, Suwahyuni Muslimin, Lukman Nurjannah Bachri, Nurjannah Nursamsiar Nursamsiar paluseri, Andi Pratiwi Utami, Yuri Rahmah Mustarin Rosyid, Sujud Z S, St. Mujahida Sami, Fitriyanti Sari, Lely Meriaya Solly Aryza Sri Wahyuni Sukriani Kursia, Sukriani Syamsu Nur, Syamsu Umar, Abd. Halim Utami, Yuri Pratiwi Zaenal Zaenal, Zaenal