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Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya
Published by Universitas Muhammadiyah Surabaya
ISSN : 25412272     EISSN : 25489526     DOI : -
Core Subject : Health,
Health Professions Medicine & Pharmacology
Arjuna Subject : -
Articles 301 Documents
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Index and Acknowledgement Yelvi Levani
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 4, No 2 (2020)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v4i2.5598

Abstract

Index and Acknowledgement
Electrocardiogram abnormality and Distance Covered during Six Minute Walk Test on Diabetes Mellitus Type 2 Ni Made Elva Mayasari; Adhi Permana; Yudi Fadilah; Namira Amanda
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 4, No 2 (2020)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v4i2.3598

Abstract

AbstractDiabetes Mellitus (DM) is a metabolic disease that has the characteristics of hyperglycemia that occurs due to abnormalities of insulin secretion, insulin action, or both. Macrovascular complications are often also referred to as secondary atherosclerosis due to DM, which can cause cerebral vascular disease, coronary arterial disease, and peripheral atrial disease. Diagnostic tools are needed for early detection in cardiovascular diseases which is accurate, inexpensive, comfortable, and available in almost health center. One of the diagnostic tools for early detection of cardiovascular diseases is an electrocardiogram (ECG). Six Minute Walk Test (SMWT) is a simple, objective, inexpensive, and efficient test to assess functional capacity and prognosis. This study aims to [nmem1] see whether there is a correlation between abnormalities of ECG and distance covered during SMWT in DM patients. This study was a cross-sectional study design from DM patients in the Polyclinic of the Muhammadiyah Hospital in Palembang. Forty patients with type 2 DM who fulfilled inclusion and exclusion criteria were selected using a consecutive sampling method. Twenty-seven patients have abnormal ECG, and only thirteen patients had distance covered during SMWT >300m. There is a correlation between abnormalities of ECG and distance covered during SMWT in DM patients with a significance value p = 0.011.Keywords: Diabetes Mellitus type 2, Eelectrocardiogram, Six Minute WalkingCorrespondence author: elva.maya@yahoo.com  
Association between gestational age and persistent pulmonary hypertension of the newborn (PPHN) severity in preterm babies at Sidoarjo Regional Hospital Aisyah Faadhilah; M. Perdana Airlangga; Nurma Yuliyanasari; Gina Noor Djalilah
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 5, No 1 (2021)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v5i1.6107

Abstract

AbstractPersistent pulmonary hypertension of the newborn (PPHN) is a condition that occurs due to increased resistance to blood vessels in the lungs that occur persistently after the baby is born. This can be attributed to congenital heart disease such as right-to-left shunts through foramen ovale (PFO) or patent ductus arteriosus (PDA) due to an error transition fetal blood circulation to the neonate. Although PPHN is always associated with births in post-term babies, PPHN cases are often found in preterm babies. Chances of babies born with PPHN are quite large, at 1.9% per 1000 live births. PPHN can be fatal, causing mortality rates ranging from 4 to 33%. The incidence of preterm births in Indonesia is estimated at 7-14%, around 459,200 - 900,000 babies per year. This study aimed to prove the relationship between premature babies and persistent pulmonary hypertension of the newborn (pphn) in Sidoarjo  Regional Hospital and to know the characteristics and analyze these variables.  This research used crossed sectional studied design; the population was all preterm babies in the NICU at Sidoarjo  regional hospital. All samples are from medical records in January-December 2018. There is a significant difference between preterm babies and PPHN (p < 0.05); besides, the results from Spearman's correlation analysis obtained a correlation coefficient (ρ) = 0.485. In the cross-tabulation analysis, the result of the proportion with the highest correlation was Late Preterm babies with severe PPHN of 46.7%. It can be concluded that there is a relationship between premature babies and PPHN in Sidoarjo  regional hospital..Keywords                      : Persistent pulmonary hypertension of the newborn, PPHN, Preterm BabiesCorrespondence            : aisyahhelmadevithalib@gmail.com
Solanum betaceum Extract as a Protective on Spermatozoa Morphology of Mice Exposed to Lead Acetate Rima Wirenviona; Reny I&#039;tishom; Siti Khaerunnisa; Anak Agung Istri Dalem Cinthya Riris; Nurul Fatimah Susanti; Nurul Jannatul Wahidah; Abadiyah Zakiah Kustantina
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 5, No 1 (2021)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v5i1.4594

Abstract

Environmental pollution is one of the factors that contribute to the decline in male fertility. Lead is one of six air pollutants harmful to the reproductive system. One parameter of infertility in men is an increase in reproductive function observed with decreased morphological abnormalities of spermatozoa. The purpose is to analyze the effect of giving various dosages of Solanum betaceum extract on spermatozoa morphology of mice exposed to lead acetate. This study was true experimental using a randomized post-test only control group design. The total sample was 40 male mice Balb/ C taken by simple random sampling technique. Treatment and maintenance of experimental animals for 35 days. Statistical tests showed there were significant differences with p-value 0.005. Solanum betaceum extract can be used as a protective to improve the normal morphology spermatozoa of mice that exposed to lead acetate.
Oxygen saturation among newborns in the first 10 hours of life to detect Critical Congenital Heart Disease - Ductus Dependent Fatchul Wahab; Mahrus Abdul Rahman; Teddy Ontoseno; Risa Etika; Alit Utamayasa; Taufiq Hidayat; Sarmanu Sarmanu
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 4, No 2 (2020)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v4i2.4258

Abstract

ABSTRACT Delay diagnosis of Critical Congenital Heart Disease (CHD) can be associated with sudden clinical deterioration and dangerous cardiovascular conditions. The oxygen saturation screening among newborns in the first 10 hours of life is essential for early detection of critical CHD. This study aims to prove that measuring oxygen saturation among newborns in the first 10 hours of life can detect critical CHD. This study is a diagnostic experimental with consecutive sampling subjects in the infant care unit of Dr. Soetomo Hospital, including all newborns with birth weight ≥ 1500 grams and oxygen saturation at ≥ 1 hour of age below 90%. The measurement of oxygen saturation uses fingertip pulse oximetry in the right hand and foot at the age of 10 hours. A "positive oxygen saturation" is defined as oxygen saturation ≤ 85% or different oxygen saturation ≥ 3%, while a "negative oxygen saturation" is when the oxygen saturation is 85% to 90% or different oxygen saturation is 3%. Echocardiography is performed for the gold standard. From November 2019 to January 2020, 11 newborns underwent an oxygen saturation examination. Five subjects (45.46%) in the category of positive oxygen saturation, echocardiographic showed all Critical CHD (100%). Six subjects (54.54%) with negative oxygen saturation category, echocardiographic results showed two critical CHD (33.34%) and four non-critical CHD (66.66%). Fisher's exact test p < 0.005 (α). The diagnostic oxygen saturation test among newborns at 10 hours of life shows ≤85%, all subject’s echocardiography (100%) shows detection of critical CHD, while saturation 85% to 90% has of 33.3% for detection of critical CHD. The sensitivity and specificity of oxygen saturation for early diagnosis of critical CHD are 100% and 67%, respectively. Keywords: critical congenital heart disease, oxygen saturation, fingertip pulse oximetry, diagnostic tests*Corresponding Author: wfatchul045@gmail.com
Relationship of Prostate-Specific Antigen (PSA) and Prostate Volume in Patients with Biopsy Proven Benign Prostatic Hyperplasia (BPH) Aulia Nur Fadila; Anny Setijo Rahaju; Tarmono Tarmono
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 4, No 2 (2020)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v4i2.3426

Abstract

Abstract  Benign prostatic hyperplasia (BPH) is one of the most common benign tumors in men with prevalence ranging from 50% for men in their 60s to 90% for men in their 80s. The researcher sought to determine the relationship of prostate-specific antigen (PSA) and prostate volume in patients with benign prostatic hyperplasia. This study was based on 33 cases of benign prostatic hyperplasia in the Department of Urology, RSUD Dr. Soetomo Surabaya that diagnosed by histopathology examination. Cases with malignancy, acute urinary retention and prostatitis were excluded. The variables of prostate-specific antigen and prostate volume were examined. The results of this study found that 33 men were enrolled with mean PSA 16,04 ng/ml and a mean prostate volume of 49,13 ml. Overall, 84,8% had PSA level >4 ng/ml and 90,9% had prostate volume >25 ml. Prostate-specific antigen has significant correlation with prostate volume (p=0,019; r=0,362). This study concluded that prostate-specific antigen and prostate volume showed a significant correlation. Keywords             : benign prostatic hyperplasia, prostate specific antigen, prostate volumeCorrespondence   : anny_sr@fk.unair.ac.id
The association between demographic and attitude factors with the practice of malaria prevention among the rural community in Purworejo district, Indonesia Farindira Vesti Rahmasari; Winny Setyonugroho; I Ketut Swarjana; Desto Arisandi; Tri Wulandari Kesetyaningsih
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 5, No 1 (2021)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v5i1.5416

Abstract

Abstract Malaria is one of the global health problems that is faced by many countries, including Indonesia. This study aimed to examine the association between demographic and attitude factors with malaria prevention in the rural areas of Purworejo District, Indonesia. A community survey was conducted in Purworejo District that involved 147 respondents by using simple random sampling to select the respondents. A questionnaire interview was used to collect data about demographic factors, attitudes, and malaria prevention practices. A Chi-square test was performed to examine the association between demographic and attitude factors with the practice of malaria prevention in the community. Among 147 respondents, 80 (54.4%) respondents conducted malaria prevention practice using bed mosquito net in their own houses. Demographic factors such as education level (p<0.001), occupation (p=0.016), and attitude factor (p=0.006) were significantly associated with the use of bed mosquito net for malaria prevention practice. Meanwhile, 63 (42.9%) respondents used ventilation mosquito net for malaria prevention practice. Demographic factors such as education level (p<0.001), age groups (p=0.005), occupation (p=0.002), and attitude factor (p=0.001) were associated significantly with the use of ventilation mosquito net for malaria prevention practice. Overall, malaria prevention by using both bed and ventilation mosquito nets were very low percentages. Keywords             : Malaria, prevention practice, mosquito net, IndonesiaCorrespondence   : farindira.vesti@gmail.com
Characteristics of complaints and functional outcomes of conservatively treated clavicle fractures in Dr. Soetomo general hospital: A case series Brilliant Citra Wirashada; Maghrizal Roychan; Teddy Heri Wardhana
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 5, No 1 (2021)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v5i1.3142

Abstract

ABSTRACT  Shoulder pain is a major complaint of patients with clavicle fractures as a result of trauma. At present most clavicle fracture treatments are performed surgery, although conservative therapy can produce the same results. This report aimed to show whether there were complaints of shoulder pain or disability in patients who have suffered clavicle fractures treated conservatively. There were fifteen patients with clavicle fractures at Dr. Soetomo Surabaya from January to July 2015, consisting of 14 male and one female patient. Data was taken from medical records, patient clinical records, home visits, physical examinations, SPADI questionnaires, and Quick DASH for patients. The results of SPADI questionnaire were varied; there were eight patients (53%) with an output of 0%, one patient (7%) each with a score of 0.63%, 1.25%, 5.90%, 7.13%, 8.50%, 9.90%, and a score of 10.50%. The results of calculating the Quick DASH questionnaire score also varied. There were ten patients (67%) with a score of 0, three patients (20%) with a score of 2.27, one patient (7%) with a score of 13.6, and one patient (6%) with a score of 6.81. In conclusion: (1) From the evaluation of 15 patients, there were no complaints of pain and disability in the shoulder joint. (2) From the evaluation of the results of the calculation of the SPADI questionnaire and Quick DASH, there were no significant complaints of shoulder joint pain and disability. (3) The conservative treatment of closed fractures on the clavicle can still be a reliable choice of treatment. Keywords                 : Clavicle fractures, shoulder pain, conservative clavicle.Correspondence to: brijurnalqanun@gmail.com  
Effects of Prebiotics, Probiotics, and Synbiotics on the Bodyweight, Blood Glucose, Triglyceride and TNF-α of Diet-induced Obesity Rats Lenny Octavia; Soebagijo Adi Soelistijo; Agung Dwi Wahyu Widodo
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 4, No 2 (2020)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v4i2.4206

Abstract

Abstract  High-fat diet leads to obesity-associated chronic low-grade inflammation. Prebiotics, probiotics, and synbiotics produced short-chain fatty acids (SCFA), bonded to G protein-coupled receptors (GPR)-41 and GPR-43 decreased triglyceride deposits in adipocytes and liver, decreased fatty acid oxidation, increased glucose regulation and insulin sensitivity thus reduced the risk of obesity and metabolic syndrome. This study conducted in order to evaluate the effects of prebiotics, probiotics, and synbiotics on the body weight, blood glucose, triglyceride, and TNF-α used rats model, which were fed by a high-fat diet. Thirty-eight 6-8 weeks old male rats were fed by high-fat diet for three weeks, then rats were randomly divided into four groups, high-fat diet (HFD), a high fat diet with prebiotics supplementation (HFD+ PRE), a high fat diet with probiotics supplementation (HFD+PRO), and high-fat diet with synbiotics supplementation (HFD+SYN) for three weeks. Blood samples and body weight were measured at the third and sixth week. There was no effect of prebiotics, probiotics, and synbiotics on body weight, triglyceride levels, blood glucose, and TNF-α in rats fed a high-fat diet compared to control. These results suggested that supplementations gave inconsistent results with other studies and needed further researches.Keywords             : high fat diet, prebiotics, probiotics, synbiotics, meta-inflammationCorrespondence   : soebagijo@yahoo.com
IN VITRO TEST: Antimicrobial Activity Potential From Ciplukan Fruit (Physalis minima L.) Extract in Methicillin-resistant Staphylococcus aureus (MRSA) Muhammad Hanun Mahyuddin; Arifa Mustika; Gwenny Ichsan Prabowo; Deby Kusumaningrum
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 4, No 2 (2020)
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v4i2.3645

Abstract

In Indonesia, in 2006 the prevalence of infections due to MRSA was 23.5%. Physalis minima L. plants are known to have antimicrobial activity because they contain compounds withaferin A which can induce programmed cell death. This research was to determine the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of Ciplukan (Physalis minima L.) extract in Methicillin-resistant Staphylococcus aureus (MRSA) bacteria. Dilution test with Mueller-Hinton broth medium used for measuring the minimum inhibitory concentration (MIC). Ciplukan  fruit extract was dissolved in distilled water, and poured into a test tube with a certain concentration (0.9 g/mL (90%); 0.3 g/mL (45%); 0.15 g/mL (22.5%); 0.075 g/mL (11.25%) and 0.0375 g/mL (5.625%). After being incubated for 24 hours, the bacteria in the test tube were plated on nutrient agar plates, to determine the MBC. The MIC cannot be determined, because the solution in the dilution test tube is disturbed by the color of the extract so that turbidity cannot be observed. From the observations of the minimum bactericidal concentration MBC of the Ciplukan (Physalis minima  L.) fruit extract against MRSA was in the P1 tube or equivalent to 0.9 g / ml (90%).

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