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JRST (Jurnal Riset Sains dan Teknologi)
ISSN : 25799118     EISSN : 25499750     DOI : http://dx.doi.org/10.30595/jrst
JRST (Jurnal Riset Sains dan Teknologi) adalah jurnal peer reviewed dan Open-Acces. JRST merupakan jurnal yang diterbitkan oleh Lembaga Publikasi Ilmiah dan Penerbitan (LPIP) Universitas Muhammadiyah Purwokerto. JRST mengundang para peneliti, dosen, dan praktisi di seluruh dunia untuk bertukar dan memajukan keilmuan di bidang sains dan teknologi yang meliputi bidang Matematika, Kimia, Biologi, Teknologi Rekayasa dan Keteknikan, Farmasi, Geografi, Komputer dan Teknologi Informasi. Dokumen yang dikirim harus dalam format Ms. Word dan ditulis sesuai dengan panduan penulisan. JRST terbit 2 kali dalam setahun pada bulan Maret dan September.
Articles 24 Documents
Search results for , issue "Volume 10 No. 1, March 2026: JRST" : 24 Documents clear
Application of Symbiotic Culture of Bacteria and Yeast Kombucha Gel on Incision and Burn Wounds in Mice (Mus musculus): Aplikasi Gel Symbiotic Culture of Bacteria dan Yeast Kombucha pada Luka Sayat dan Bakar Mencit (Mus musculus) Andiarna, Funsu; Hidayati, Irul; Agustina, Eva; Purnamasari, Risa
JRST (Jurnal Riset Sains dan Teknologi) Volume 10 No. 1, March 2026: JRST
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/jrst.v10i1.24079

Abstract

SCOBY (Symbiotic Culture of Bacteria and Yeast) is a result of kombucha tea fermentation that contains active compounds, such as phenolic acids and flavonoids, which possess high antioxidant activity. However, the use of SCOBY is currently limited to serving as a starter culture for new batches of kombucha tea, necessitating innovation to enhance its other potential benefits. This study aims to evaluate the effectiveness of kombucha SCOBY gel in the healing of incised and burn wounds in mice (Mus musculus). The research methods included the preparation of kombucha tea, harvesting of SCOBY, formulation of gel, application of the gel to incised and burn wounds in mice, and observation of wound healing until closure. The results showed that kombucha SCOBY gel significantly accelerated the healing of both incised and burn wounds compared to the control group. Incised wounds fully healed by day 6, while burn wounds healed by day 7. This effectiveness is associated with the high total phenolic content (TPC) of the SCOBY gel, measured at 790.4 mg GAE/g extract, along with strong antioxidant activity of 12.42% (DPPH assay). Statistical analysis revealed a significant difference (p<0.05) in wound healing between the untreated and SCOBY gel-treated groups for both types of wounds. Therefore, kombucha SCOBY gel has potential as an effective natural topical wound-healing agent, particularly for mild to moderate wounds.   ABSTRAK (Bahasa Indonesia) SCOBY (Symbiotic Culture of Bacteria and Yeast) merupakan hasil fermentasi teh kombucha yang mengandung senyawa aktif, seperti asam fenolat dan flavonoid, yang memiliki aktivitas antioksidan tinggi. Namun penggunaan SCOBY hanya terbatas sebagai starter dalam pembuatan teh kombucha baru, sehingga diperlukan inovasi untuk meningkatkan manfaat lain dari SCOBY. Tujuan penelitian ini adalah untuk mengevaluasi efektivitas gel SCOBY kombucha dalam penyembuhan luka sayat dan luka bakar pada mencit (Mus musculus). Metode penelitian ini dimulai dari pembuatan teh kombucha, pemanenan SCOBY, pembuatan gel pengaplikasian pada luka sayat dan bakar pada mencit dan pengamatan penyembuhan luka sampai penutupan luka. Hasil penelitian menunjukkan bahwa gel SCOBY kombucha mempercepat penyembuhan luka sayat dan bakar secara signifikan dibandingkan kelompok kontrol. Luka sayat sembuh sempurna pada hari ke‑6, sedangkan luka bakar sembuh pada hari ke‑7. Efektivitas ini dikaitkan dengan tingginya kadar total fenolik (TPC) gel SCOBY, yaitu sebesar 790,4 mg GAE/g ekstrak, serta aktivitas antioksidan kuat sebesar 12,42% (uji DPPH). Hasil analisis statistik menyatakan pada luka sayat dan bakar terdapat perbedaan signifikan(p<0,05) antara kelompok tanpa perlakuan dan gel SCOBY. Dengan demikian, gel SCOBY kombucha berpotensi sebagai agen penyembuh luka topikal alami yang efektif, khususnya untuk luka ringan hingga sedang.
Coordinate Stability Analysis of PT PLN Customers with Variance and DBSCAN Clustering: Pontianak Case Study: Analisis Stabilitas Koordinat Pelanggan PT PLN dengan Variansi dan DBSCAN Clustering: Studi Kasus Pontianak Ayu, Oktavia Arnelliza; Haryadi, Agus; Kusumastuti, Nilamsari; Dzulqarnain, Muhammad Faqih
JRST (Jurnal Riset Sains dan Teknologi) Volume 10 No. 1, March 2026: JRST
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/jrst.v10i1.24866

Abstract

PT PLN (Persero) is a major electricity provider in Indonesia that relies on accurate spatial data management to support various operations, such as electricity bill delivery and network expansion planning. Accurate spatial data also plays an important role in making strategic decisions regarding future network development. This research aims to identify stable coordinate points and analyze clustering results using DBSCAN (Density-Based Spatial Clustering of Applications with Noise) on postpaid customer spatial data in Pontianak City, with a focus on the geographic coordinate point distance of customer homes. The dataset used includes information on the home coordinates of postpaid customers of PT PLN (Persero) Pontianak City from February to July 2024. Variance analysis was applied to determine which coordinate points were considered stable, while DBSCAN was used to determine clusters and identify noise based on data density. With an epsilon parameter of 0.0036 and minimum points (minPts) of 15, the results show two main clusters, the first cluster consists of 50 points and the second cluster consists of 18 coordinate points of customer house locations. In addition, no noise was detected in the data set. The results of this research provide strategic benefits for PT PLN. The main cluster allows PLN to prioritize network development in areas with high customer density to maintain optimal service quality. Meanwhile, although no noise was detected in this study, if there are low-density areas in other analyses, special strategies need to be designed to support service improvement in these areas.   ABSTRAK (Bahasa Indonesia) PT PLN (Persero) merupakan perusahaan penyedia listrik utama di Indonesia yang mengandalkan pengelolaan data spasial yang akurat untuk mendukung berbagai operasi, seperti pengiriman tagihan listrik dan perencanaan perluasan jaringan. Data spasial yang akurat juga memainkan peran penting dalam pengambilan keputusan strategis terkait pengembangan jaringan di masa depan. Penelitian ini bertujuan untuk mengidentifikasi titik koordinat yang stabil serta menganalisis hasil klasterisasi menggunakan DBSCAN (Density-Based Spatial Clustering of Applications with Noise) pada data spasial pelanggan pasca bayar di Kota Pontianak, dengan fokus pada jarak titik koordinat geografis rumah pelanggan. Dataset yang digunakan mencakup informasi titik koordinat rumah pelanggan pasca bayar PT PLN (Persero) Kota Pontianak dari Februari hingga Juli 2024. Analisis variansi diterapkan untuk menentukan titik koordinat yang dianggap stabil, sementara DBSCAN digunakan untuk menentukan klaster dan mengidentifikasi noise berdasarkan kepadatan data. Dengan parameter epsilon  sebesar 0,0036 dan minimum points (minPts) sebanyak 15, hasil menunjukkan dua cluster utama yaitu cluster pertama terdiri dari 50 titik dan cluster kedua terdiri dari 18 titik koordinat lokasi rumah pelanggan. Selain itu, tidak ada noise yang terdeteksi dalam data set. Hasil penelitian ini memberikan manfaat strategis bagi PT PLN. Klaster utama memungkinkan PLN dapat memprioritaskan pengembangan jaringan diarea dengan kepadatan pelanggan tinggi guna menjaga kualitas layanan tetap optimal. Sementara itu, meskipun tidak terdeteksi noise pada penelitian ini, jika terdapat area dengan kepadatan rendah pada analisis lain, strategi khusus perlu dirancang untuk mendukung peningkatan layanan diarea tersebut
Project Cost and Time Performance Analysis using the Earned Value Concept Method in Building Shophouses in Papua: Analisa Kinerja Biaya dan Waktu Proyek dengan Metode Earned Value Concept dalam Pembangunan Ruko di Papua Lazuardi, Fajar; Rizki, Muhammad Alvan
JRST (Jurnal Riset Sains dan Teknologi) Volume 10 No. 1, March 2026: JRST
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/jrst.v10i1.25969

Abstract

In construction implementation, effective management of cost, time, and resources is crucial to avoid the risk of project failure. Many problems encountered in construction projects stem from discrepancies between actual execution and initial planning, as well as a lack of accuracy in cost estimation during the planning phase, which can lead to budget overruns and scheduling deviations. This study aims to evaluate project performance using the Earned Value Concept (EVC) by assessing the ongoing work performance to provide a comprehensive overview of project efficiency. The research employs a descriptive quantitative method with an analytical approach to weekly project progress data collected at weeks 20, 23, 25, 27, and 30. The results indicate that the project experienced delays, as reflected by the Schedule Performance Index (SPI) consistently remaining below 1 and negative Schedule Variance (SV) values. Cost efficiency was initially achieved with a Cost Performance Index (CPI) of 1.23 in the early phase, but declined to 0.88 by week 30 due to increased actual costs. Based on estimation, the project is expected to be completed in 38 weeks, exceeding the original plan of 35 weeks, with a total projected cost of IDR 22,436,134,730.24, which is lower than the original budget of IDR 25,001,696,716.00   ABSTRAK (Bahasa Indonesia) Dalam Pelaksanaan konstruksi manajemen terhadap biaya, waktu, dan sumber daya sangat penting, untuk menghindari risiko kegagalan dalam pelaksanaan konstruksi. Banyak permasalahaan dalam pelaksanaan proyek konstruksi yang disebabkan karena ketidaksesuaian pelaksanaan dengan rencana, serta kurang ketelitian perhitungan biaya dalam tahap perencanaan yang dapat mengakibatkan pembengkakan biaya, selain itu ketidaksesuaian waktu yang direncanakan. Penelitian ini bertujuan untuk mengkaji kinerja proyek dengan pendekatan earned value concept dengan menilai kinerja pekerjaan yang sedang berlangsung sehingga dapat diperoleh gambaran mengenai evaluasi kinerja proyek. Penelitian ini menggunakan metode kuantitatif deskriptif, dengan pendekatan analitis terhadap data progres mingguan proyek pada minggu ke-20, 23, 25, 27, dan 30. Hasil penelitian menunjukkan bahwa proyek mengalami keterlambatan, tercermin dari nilai SPI yang selalu di bawah 1 dan SV yang bernilai negatif. Efisiensi biaya sempat tercapai pada awal pelaksanaan dengan CPI sebesar 1,23, namun menurun hingga 0,88 pada minggu ke-30 akibat peningkatan biaya aktual. Berdasarkan estimasi, proyek diperkirakan selesai dalam 38 minggu dari rencana awal 35 minggu, dengan total biaya penyelesaian sebesar Rp22.436.134.730,24, lebih rendah dari anggaran awal Rp25.001.696.716,00.
Cyberloafing Analytics: Predicting Causes Using Machine Learning Models Ferdiansah, Gilang; Yuadi, Imam
JRST (Jurnal Riset Sains dan Teknologi) Volume 10 No. 1, March 2026: JRST
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/jrst.v10i1.25997

Abstract

Cyberloafing refers to the practice of employees utilizing internet access for non-job-related activities during work hours. Cyberloafing poses a dilemma for organizations, as it is deemed aberrant conduct that might impact overall performance. Consequently, organizations must ascertain the determinants of cyberloafing. This study seeks to identify a suitable predictive model for the determinants of cyberloafing behavior in the workplace using a machine learning methodology. The employed methodology utilizes the conventional data mining cycle, namely the Cross-Industry Standard Process for Data Mining (CRISP-DM), with Orange Data Mining as the application tool. The findings indicate that Logistic Regression is the most effective model for forecasting cyberloafing. Logistic Regression yields performance scores of 90.5% Precision and 88.9% Recall. Conversely, the Naïve Bayes model had the lowest metrics, with a Precision of 64.8% and a Recall of 51.9%. This study serves as a reference demonstrating that Logistic Regression effectively predicts cyberloafing. This study enables firms to examine the factors contributing to cyberloafing, facilitating the development of policies aimed at mitigating its adverse effects.
Antibacterial Property Evaluation of Ethanolic Extract of Plantago major L. and Its Fractions Prismawan, Deka; Michael; Gunawan, Gwyneth Yovela; Kambira, Pretty Falena Atmanda
JRST (Jurnal Riset Sains dan Teknologi) Volume 10 No. 1, March 2026: JRST
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/jrst.v10i1.26388

Abstract

The escalating global health crisis of antibiotic resistance necessitates the search for novel antibacterial agents from natural sources. This study investigated the potential of Plantago major L., a plant used in traditional medicine, as a source of antibacterial compounds. It aimed to evaluate the antibacterial activity of its ethanol extract and its polarity-based fractions against Escherichia coli and Staphylococcus aureus. Dried P. major L. leaves were extracted with ethanol using maceration. The crude extract was then fractionated using a sequential liquid-liquid extraction with hexane, ethyl acetate, and n-butanol. The antibacterial activity of the extract and all fractions was tested against S. aureus (ATCC 25923) and E. coli (ATCC 25922) using the broth microdilution method to determine the Minimum Inhibitory Concentration (MIC). Results revealed distinct antibacterial profiles based on fraction polarity. The ethyl acetate fraction exhibited the strongest activity against S. aureus with an MIC of 0.104 mg/mL, indicating the presence of potent semi-polar compounds like flavonoids effective against gram-positive bacteria. Conversely, the n-butanol fraction was most effective against E. coli with an MIC of 3.3 mg/mL, suggesting the role of hydrophilic compounds such as saponins in disrupting the more complex gram-negative membrane. The crude ethanol extract showed lower activity, confirming the critical role of fractionation in concentrating the bioactive compounds. Plantago major L. possesses significant antibacterial potential, with its active compounds concentrated in specific polarity-based fractions. These findings validate its traditional use and support its further development as an alternative therapy in the face of growing antibiotic resistance.
Conveyor Performance Analysis In Secondary Packaging Using the Time and Motion Study Method: Analisis Kinerja Conveyor pada Pengemasan Sekunder dengan Metode Time And Motion Study Fadhli, Haiyul; Anggraeni, Ica Winanda; Mudia, Whulan; Kamil, Marshal M.
JRST (Jurnal Riset Sains dan Teknologi) Volume 10 No. 1, March 2026: JRST
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/jrst.v10i1.26423

Abstract

To avoid a shortage of drug stocks in the market with the high number of market demands, PT. Trifa Raya Laboratories always evaluates to achieve good product quality, one of which is in the field of packaging by optimizing the amount of labor and time needed using conveyor tools. The purpose of this study is to determine the optimal amount of manpower needs in the secondary packaging process at PT. Trifa Raya Laboratories using the Time and Motion Study method. This method was chosen to measure the time and efficiency of worker movements in each packaging activity, so that it can increase productivity. Data were collected through direct observation in the field with variations in the number of workers (5, 6, and 7 people) and were carried out three times every 5 minutes at different times. The results showed that the packaging of envelopes and small boxes was optimal with 7 workers, resulting in productivity per person of 21.33 and 52.24 respectively. Meanwhile, the packaging of medium and large boxes is optimal with 5 and 6 workers, resulting in productivity per person of 68.53 and 65.44 respectively. The conclusions of this study emphasize the importance of determining the ideal number of workers to increase efficiency and productivity in the secondary packaging process, as well as the need to pay attention to the level of complexity of packaging and the skills of workers. ABSTRAK (Bahasa Indonesia) Untuk menghindari kekosongan stok obat di pasaran dengan tinggi nya jumlah permintaan pasar, PT. Trifa Raya Laboratories selalu melakukan evaluasi untuk mencapai mutu produk yang baik salah satunya pada bidang pengemasan dengan mengoptimalkan jumlah tenaga kerja dan waktu yang dibutuhkan menggunakan alat conveyor. Tujuan dari penelitian ini untuk menentukan jumlah kebutuhan tenaga kerja yang optimal pada proses pengemasan sekunder di PT. Trifa Raya Laboratories dengan menggunakan metode Time and Motion Study. Metode ini dipilih untuk mengukur waktu dan efisiensi gerakan pekerja dalam setiap aktivitas pengemasan, sehingga dapat meningkatkan produktivitas. Data dikumpulkan melalui observasi langsung di lapangan dengan variasi jumlah pekerja (5, 6, dan 7 orang) dan dilakukan sebanyak tiga kali setiap 5 menit pada waktu yang berbeda. Hasil penelitian menunjukkan bahwa pengemasan dus amplop dan kecil optimal dengan 7 pekerja, menghasilkan produktivitas per orang masing-masing sebesar 21,33 dan 52,24. Sementara itu, pengemasan dus sedang dan besar optimal dengan 5 dan 6 pekerja, menghasilkan produktivitas per orang masing-masing sebesar 68,53 dan 65,44. Kesimpulan dari penelitian ini menekankan pentingnya penentuan jumlah tenaga kerja yang ideal untuk meningkatkan efisiensi dan produktivitas dalam proses pengemasan sekunder, serta perlunya perhatian terhadap tingkat kerumitan pengemasan dan keterampilan pekerja.
Analysis of Alternative Substitute Materials for Concrete Production Using Word Cloud Andaryati, Andaryati; Suharso, Akbar Bayu Kresno; Raharja, Danang Setiya; Saurina, Nia
JRST (Jurnal Riset Sains dan Teknologi) Volume 10 No. 1, March 2026: JRST
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/jrst.v10i1.26434

Abstract

Concrete is a construction material whose use continues to increase every year. This need is based on concrete forming materials, especially cement, which has experienced quite a large increase. Word cloud is a system that creates visualizations of words by emphasizing the frequency of occurrence of related words in written discourse. This research uses the text mining method with the help of Word Cloud and Term Document Matrix to analyze 76 articles as a dataset that discuss various concrete substitute materials including husk ash, dry bamboo leaves, construction waste, husk ash, and shells. The use of Word Cloud in the analysis of concrete substitute materials provides a fast and effective visualization of the frequency and relevance of words in the text and helps identify environmentally friendly substitute materials, the most widely used in the industrial world and has concrete compressive strength according to concrete quality standards based on the frequency of word occurrences. key in the dataset
Identification of Single Nucleotide Variation (SNV) -1082 A/G Gen Interleukin 10 (IL-10) in Tuberculosis Patients Using ARMS-PCR Method: Identifikasi Single Nucleotide Variation (SNV) -1082 A/G (rs1800896) Gen Interleukin 10 (IL-10) pada Penderita Tuberkulosis Menggunakan Metode ARMS-PCR Saroh, Dewi; Hana, Aninda
JRST (Jurnal Riset Sains dan Teknologi) Volume 10 No. 1, March 2026: JRST
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/jrst.v10i1.26435

Abstract

Tuberculosis (TB) is a significant global health problem and remains one of the leading causes of high morbidity and mortality worldwide. Genetic variation in the interleukin-10 (IL-10) gene, particularly SNV -1082 A/G (rs1800896), plays an important role in regulating the immune response to Mycobacterium tuberculosis. This study aimed to determine the distribution of genotypes and alleles of SNV -1082 A/G (rs1800896) in the IL-10 gene among tuberculosis patients and healthy individuals. A descriptive study was conducted using a total of 12 blood samples (6 active TB patients from Puskesmas Delanggu Klaten and 6 healthy individuals as controls). Identification of the SNV was performed using the ARMS-PCR method, followed by electrophoresis and DNA band analysis. The results showed that the A/A genotype was more frequently observed in TB patients, while the A/G genotype was more frequent in healthy individuals. The A allele was more dominant in TB patients, whereas the G allele was more common in the healthy group. These findings provide a preliminary overview of genotype and allele distribution in a limited population. However, the very small sample size represents a major limitation of this study, and therefore the findings should only be considered preliminary and cannot be generalized. Further studies with larger sample sizes are required to confirm these results.   ABSTRAK (Bahasa Indonesia) Tuberkulosis (TB) merupakan masalah kesehatan global yang signifikan dan masih menjadi penyebab morbiditas dan mortalitas tinggi. Variasi genetik pada gen interleukin-10 (IL-10), khususnya SNV -1082 A/G (rs1800896), berperan penting dalam regulasi respon imun terhadap Mycobacterium tuberculosis. Penelitian ini bertujuan untuk mengetahui distribusi genotipe dan alel SNV -1082 A/G (rs1800896) gen IL-10 pada pasien tuberkulosis dan individu sehat. Penelitian dilakukan secara deskriptif dengan total 12 sampel darah (6 pasien TB aktif dari Puskesmas Delanggu Klaten dan 6 individu sehat sebagai kontrol). Identifikasi SNV dilakukan menggunakan metode ARMS-PCR, dilanjutkan dengan elektroforesis dan analisis pita DNA. Hasil menunjukkan bahwa genotipe A/A lebih banyak ditemukan pada pasien TB, sedangkan genotipe A/G lebih banyak pada individu sehat. Alel A lebih dominan pada pasien TB, sementara alel G lebih banyak pada kelompok sehat. Hasil ini memberikan gambaran awal distribusi genotipe dan alel pada populasi terbatas. Namun, jumlah sampel yang sangat kecil menjadi keterbatasan utama penelitian ini, sehingga temuan hanya dapat dianggap sebagai data awal (preliminary) dan belum dapat digeneralisasi. Penelitian lanjutan dengan jumlah sampel lebih besar sangat diperlukan untuk mengonfirmasi hasil ini    
Analysis of risk factors for recurrent stroke in stroke patients: Analisis Faktor Risiko Kejadian Stroke Berulang Pada Pasien Stroke Dwiyanti, Luvty S.L.; Abdillah, Syamsudin; Sumarny, Ros; Diandy, M. Ivan
JRST (Jurnal Riset Sains dan Teknologi) Volume 10 No. 1, March 2026: JRST
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/jrst.v10i1.26489

Abstract

Stroke is the second leading cause of death after heart disease. It is reported that annually, over 15 million people worldwide suffer a stroke, resulting in disability or death. Indonesia has the highest stroke mortality rate among countries in Southeast Asia. Within 30 days, the risk of recurrent stroke is very high, with one contributing factor being non-adherence to antiplatelet therapy for recurrent stroke prevention. This study aimed to analyze medication adherence and risk factors associated with recurrent stroke incidents. The research employed an observational analytic method with a case-control study design. The study sample consisted of recurrent stroke patients and post-stroke patients, with 65 patients in each group, recruited from the neurology polyclinic of "X" Hospital in Jakarta during the period of December 2024 to January 2025. Data were collected using questionnaires and the Hospital Management Information System (SIMRS). Bivariate analysis was conducted using the Chi-Square test, and multivariate analysis was performed using multiple logistic regression. The results indicated that the respondent characteristics in both groups were patients aged 18–64 years, male, unemployed, and with low income below the regional minimum wage. Bivariate analysis identified the following risk factors associated with recurrent stroke: medication adherence, physical activity, blood pressure levels, and triglyceride levels. Multivariate analysis. ABSTRAK (Bahasa Indonesia) Stroke merupakan penyebab kematian tertinggi kedua setelah penyakit jantung, Dilaporkan bahwa setiap tahun >15 juta orang diseluruh dunia menderita stroke yang mengalami disabilitas bahkan kematian. Indonesia merupakan Negara dengan angka kematian tertinggi pada penderita stroke di Asia Tenggara. Dalam waktu 30 hari, resiko stroke berulang sangat tinggi, Salah satu pemicunya adalah ketidakpatuhan terhadap terapi pencegahan stroke berulang dengan antiplatelet. Penelitian ini bertujuan untuk menganalisis kepatuhan penggunaan obat dan faktor risiko yang berhubungan dengan kejadian stroke berulang. Metode penelitian yang digunakan adalah observasional analitik dengan desain case control study. Sampel penelitian adalah pasien stroke berulang dan pasien pasca stroke dengan jumlah sampel masing – masing sebanyak 65 pasien di poli saraf Rumah sakit “X” Jakarta periode Desember 2024 – Januari 2025. Pengambilan data menggunakan kuesioner dan SIMRS (Sistem Manajemen Rumah Sakit). Analisis bivariat menggunakan Chi Square, analisis multivariat dengan regresi logistik berganda. Hasil penelitian menunjukkan bahwa karakteristik responden di kedua kelompok adalah pasien dengan usia 18 – 64 tahun, berjenis kelamin laki – laki, tidak bekerja dan memiliki pendapatan rendah di bawah UMR. Secara bivariat, diperoleh faktor risiko yang berhubungan dengan kejadian stroke berulang adalah kepatuhan penggunaan obat, aktivitas fisik, nilai tekanan darah dan nilai trigliserida. Hasil analisis multivariat, variabel yang paling dominan berhubungan dengan kejadian stroke berulang adalah nilai tekanan darah yang tidak terkontrol (OR 0.216 dengan CI 0.086-0.543) pasien dengan nilai tekanan darah yang tidak terkontrol memiliki risiko 4.6 kali mengalami kejadian stroke berulang dibandingkan dengan pasien yang mempunyai nilai tekanan darah terkontrol.    
Bioethanol Synthesis from Areca Nut (Arecha catechu L.) Fiber Waste through Variations in Hydrochloric Acid Concentration and Hydrolysis Time: Sintesis Bioetanol dari Limbah Sabut Pinang (Arecha catechu L.) melalui Variasi Konsentrasi Asam Klorida Dan Waktu Hidrolisis Kolo, Sefrinus Maria Dolfi; Edi, Eduardus; Aki, Desidarius
JRST (Jurnal Riset Sains dan Teknologi) Volume 10 No. 1, March 2026: JRST
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/jrst.v10i1.26945

Abstract

Bioethanol is produced through the fermentation of glucose by microbes from biomass containing sugar, starch, cellulose, and lignocellulose. This study aims to determine the effect of varying concentrations of hydrochloric acid and hydrolysis time on the yield of reducing sugars and bioethanol concentration from areca nut husks. This study uses two independent variables, namely variations in acid concentration and hydrolysis time on the optimum acid concentration. The method used is the separate hydrolysis method and fermentation with variations in hydrochloric acid concentration of 1; 3; 5; and 7% and variations in hydrolysis time between 40; 50; 60; and 70 minutes at a temperature of 200°C. Fermentation was carried out with 10% inoculum using Saccharomyses cerevisiae yeast at room temperature for 4 days with a stirring speed of 200 rpm. Analysis of reducing sugars was carried out using a UV-Vis spectrophotometer, while ethanol content was analyzed using a GC-FID instrument. The results of the analysis showed that the optimum reducing sugar content was 65.25% obtained at a hydrochloric acid concentration of 3% and a hydrolysis time of 60 minutes. Ethanol analysis using GC-FID showed three peaks with an ethanol retention time of 3.263 minutes and an ethanol content of 22.29%.   ABSTRAK (Bahasa Indonesia) Bioetanol dihasilkan melalui fermentasi glukosa oleh mikroba dari biomassa yang mengandung gula, pati, selulosa, dan lignoselulosa. Penelitian ini bertujuan mengetahui pengaruh variasi konsentrasi asam klorida dan waktu hidrolisis terhadap perolehan gula pereduksi dan konsentrasi bioetanol dari sabut pinang. Penelitian ini menggunakan dua variabel independen, yaitu variasi konsentrasi asam dan waktu hidrolisis terhadap konsentrasi asam optimum. Metode yang digunakan adalah metode hidrolisis terpisah dan fermentasi dengan variasi konsentrasi asam klorida 1; 3; 5; dan 7% serta variasi waktu hidrolisis antara 40; 50; 60; dan 70 menit pada suhu 200 °C. Fermentasi dilakukan dengan inokulum 10% menggunakan khamir Saccharomyses cerevisiae pada suhu kamar selama 4 hari dengan kecepatan pengadukan 200 rpm. Analisis gula pereduksi dilakukan menggunakan spektrofotometer UV-Vis, sedangkan kadar etanol dianalisis menggunakan instrumen GC-FID. Hasil analisis menunjukkan kadar gula pereduksi optimum sebesar 65.25% yang diperoleh pada konsentrasi asam klorida 3% dan waktu hidrolisis 60 menit. Analisis etanol menggunakan GC-FID menunjukkan tiga puncak dengan waktu retensi etanol 3.263 menit dan perolehan kadar etanol sebesar 22.29%.  

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