cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
-
Contact Email
-
Phone
-
Journal Mail Official
-
Editorial Address
-
Location
Kab. sleman,
Daerah istimewa yogyakarta
INDONESIA
Indonesian Journal of Chemistry
Published by Universitas Gadjah Mada
ISSN : 14119420     EISSN : 24601578     DOI : -
Core Subject : Science, Engineering,
Chemical Engineering, Chemistry & Bioengineering Chemistry
Indonesian Journal of Chemistry is an International, peer-reviewed, open access journal that publishes original research articles, review articles, as well as short communication in all areas of chemistry including applied chemistry. The journal is accredited by The Ministry of Research, Technology and Higher Education (RISTEKDIKTI) No : 21/E/KPT/2018 (in First Rank) and indexed in Scopus since 2012. Since 2018 (Volume 18), Indonesian Journal of Chemistry publish four issues (numbers) annually (February, May, August and November).
Arjuna Subject : -
Articles 2,006 Documents
 197   198   199   200   201 
Study of Bioactivity and Physicochemical Properties of New Metal Chelates of Schiff Base Derived from 4-Aminoantipyrine with Cysteine Hussein, Kawther Adeeb; Ali, Dina Naseer; Faeq, Marwa
Indonesian Journal of Chemistry Vol 26, No 1 (2026)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.111223

Abstract

Transition metallic complexes Cr, Co, Ni, Mn, and Cu were designed and prepared using a new bidentate chelator ligand from 4-aminoantipyrine with cysteine. The products were characterized using various analytical, spectroscopic, and theoretical methods. According to the various analysis data, the azomethine-Schiff base chelator linked with metallic cations as a neutral bidentate chelator exhibited distorted octahedral and tetrahedral structures, with protonated and deprotonated carboxyl oxygen and azomethine nitrogen atoms in a molar ratio of 1:2 metal: ligand in a structure of [M(L)2Cl2]·nH2O and [M(L)2]·Cl2nH2O. According to mass spectroscopy, the molecular weights of the azomethine-Schiff base closely match those estimated by m/z. Additionally, Fourier-transform infrared (FTIR), ultraviolet-visible (UV-vis), 1H-NMR, and 13C-NMR spectra, LC-MS, magnetic moment, and molar conductance were used to study the structure of the azomethine-Schiff base ligand and metallic complexes. The antibacterial activity was tested against Staphylococcus aureus, Streptococcus pyogenes, Escherichia coli, and Acinetobacter baumannii, while the antifungal activity was evaluated against Candida albicans, Candida parapsilosis, Candida lusitaniae, and Candida tropicalis. The free ligand showed negligible activity, whereas its metal complexes exhibited moderate to strong antimicrobial effects, confirming that metal coordination significantly enhances biological potency.
Antibacterial Activities of Novel Xestospongienol Compounds: Potential Natural Agents Against Vibrio sp. Latifah, Lulu Adilla; Soekamto, Nunuk Hariani; Tahir, Akbar
Indonesian Journal of Chemistry Vol 26, No 2 (2026)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.101132

Abstract

The marine sponges, especially Xestospongia, belonging to the class Demospongiae, order Haplosclerida, family Petrosiidae, produce diverse bioactive secondary metabolites, which can be the source of potentially valuable marine natural products. These secondary metabolites could be used as alternative antibiotics to inhibit pathogenic bacteria Vibrio sp. This study aimed to isolate and characterize active compounds from Xestospongia testudinaria collected from Badi Island, South Sulawesi, Indonesia, and to evaluate their antibacterial potential. Research methods were evaporation, fractionation, purification, identification, and characterization of compounds using 1D and 2D NMR. Pure compounds were determined for their antibacterial activities using agar diffusion method against Vibrio harveyi M-120, Vibrio parahaemolyticus T-170, and Vibrio alginolyticus B-425. The fractionation and elucidation results presented two new compounds: xestospongienol, one of the types of brominated polyunsaturated acetylenic fatty acids (BPUFAs). The inhibition zone value of new compounds is 6.33–7.97 mm, where compound 2 showed higher activity than compound 1 against V. harveyi (7.97 mm). This study was the first report on the antibacterial activity of xestospongienol compounds against Vibrio sp., suggesting their potential as natural antibacterial agents.
NMR-Based Metabolic Profiling and Anticancer Activity of Nephelium ramboutan-ake and Nephelium lappaceum Flesh Febrina, Lizma; Rusli, Rolan; Samsul, Erwin; Rijai, Laode; Ahmad, Islamudin; Rusman, Arman; Hikmawan, Baso Didik; Rija'i, Hifdzur Rashif; Almeida, Maria
Indonesian Journal of Chemistry Vol 26, No 2 (2026)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.104162

Abstract

In this research, 1H-NMR-based metabolomics assessed the metabolite profiles of two Nephelium species flesh, specifically Nephelium ramboutan-ake and Nephelium lappaceum. Our research findings indicate that the metabolite profile of N. ramboutan-ake is qualitatively identical, although numerically distinct from that of N. lappaceum. The PLSDA data indicate that N. ramboutan-ake possesses elevated concentrations of acetic acid, malic acid, GABA, and succinic acid compared to N. lappaceum. In N. lappaceum, alanine and glucose serve as the distinguishing metabolites. Additionally, the anticancer efficacy of two Nephelium samples was assessed. As a result, the anticancer properties of N. ramboutan-ake were superior to those of N. lappaceum. PLS analysis indicated that GABA exhibited the most positive connection with the anticancer activity of Nephelium samples. These results indicate that the higher GABA concentrations of N. ramboutan-ake have a beneficial effect on its anticancer activity.
Effect of Citric Acid Cross-Linking on the Functional and Mechanical Properties of Chitosan-Based Edible Films with Aloe vera Gel and Red Ginger Extract Cahayo, Mafud; Iftitah, Elvina Dhiaul; Mardiana, Diah
Indonesian Journal of Chemistry Vol 26, No 2 (2026)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.105521

Abstract

Chitosan-based edible films (CBEFs) suffer from poor water vapor barrier and mechanical properties. This study investigated the effect of citric acid cross-linking and bioactive additives, including Aloe vera gel (AVG) and red ginger extract (RGE), on the physicochemical, functional, structural, and thermal properties of CBEFs. Eight formulations were prepared by dissolving 1% chitosan in either 1.25% acetic acid (A1 series) or 1.25% citric acid (A2 series), with or without the addition of 30% AVG, 0.25% RGE, or both. RGE significantly enhanced antioxidant capacity, especially in non-cross-linked CBEFs (max. 61.2-fold). Citric acid cross-linking improved film thickness and elongation, while reducing WVTR, and slightly decreased antioxidant capacity. FTIR and FE-SEM suggested that RGE primarily interacted via hydrogen bonding and ionic interactions, reinforcing the film matrix. All formulations exhibited antimicrobial activity against Escherichia coli, Staphylococcus aureus, and Xanthomonas campestris. Thermal analysis revealed that A2C3 exhibited the highest Tmax (340 °C) and a pronounced high-temperature endothermic peak (~536.8 °C), indicating superior thermal stability. When applied to cherry tomatoes, A2C3 reduced weight loss (5.27%) and preserved vitamin C (11.2 mg/100 g) over 18 days without affecting sensory acceptance. These findings highlight A2C3 as a promising natural film and coating for the preservation of fresh produce.
Precipitation, Synthesis, and Characterization of Hydroxyapatite Derived from Gonggong Snail Shells (Strombus canurium) Maritza, Najla; Dewanti, Beauty Suestining Diyah; Yuliatun, Leny
Indonesian Journal of Chemistry Vol 26, No 2 (2026)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.107110

Abstract

The gonggong snail shell contains high calcium, reaching 67.70%, which potential to be used as a source of natural hydroxyapatite. Hydroxyapatite can be used as a biomaterial for bone substitutes because it is able to integrate with bone tissue without causing toxic effects or inflammation. The purpose of this study was to analyze the effect of temperature and precipitation synthesis time on the characteristics of hydroxyapatite produced from the gonggong snail shell for bone substitute biomaterials. The results showed that precipitation at 900 °C for 4 h is the best solution for synthesizing hydroxyapatite with a Ca/P ratio of 2.76, closely approximating the stoichiometric value of HAp. SEM revealed that the synthesized HAp exhibited a spherical morphology with a tendency to form granular aggregates. FTIR confirmed the presence of characteristic PO43− and OH− functional groups. XRD analysis indicated that primary phase of the synthesized material was HAp, consistent with JCPDS data. The optimal immersion time and temperature for fabricating at 900 °C for 4 h in HAp:alginate ratio (w/w) of 2.5:7.5 (HAPT2C) based on their mechanical properties. But HAp:alginate ratio (w/w) of 5:5 (HAPT2A) demonstrated higher water absorption compared to HAPT2C in the water uptake test. HAp from gonggong snail shell are promising biomaterial candidates for bone substitution applications, warranting further investigation through in vitro and in vivo biocompatibility studies.
Synthesis of Fe3O4/Hydroxyapatite Nanocomposites: Structural, Surface, and Magnetic Characterization Fadli, Ahmad; Prabowo, Agung; Drastinawati, Drastinawati; Wandika Putra, Bima; Sugesti, Heni; Puspasari, Febriyati
Indonesian Journal of Chemistry Vol 26, No 2 (2026)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.107697

Abstract

Magnetite/hydroxyapatite (Fe3O4/HA) nanocomposites are promising materials for biomedical applications, particularly in targeted drug delivery. This study investigates the effects of hydrothermal reaction time and FeCl3 precursor concentration on the structural, morphological, and magnetic properties of Fe3O4/HA composite powders synthesized via a one-pot hydrothermal method. The resulting composites exhibit biphasic structures comprising magnetite (cubic phase) and hydroxyapatite (hexagonal phase) crystallites, with average sizes ranging from 22 to 30 nm. Both increased reaction time and FeCl3 concentration contributed to the growth of crystal size. A notable enhancement in specific surface area was observed, increasing from 48.21 to 67.41 m2/g as FeCl3 concentration decreased from 0.15 to 0.05 M at a fixed reaction time of 15 h. Magnetic characterization revealed that the composites exhibited superparamagnetic behavior, with the highest saturation magnetization (Ms) reaching 17.27 emu/g. These results demonstrate that tuning synthesis parameters can optimize the structural and magnetic properties of Fe3O4/HA nanocomposites, making them strong candidates for use in controlled drug delivery systems.
Depth Analysis of Fe2O3-Incorporated Cobalt Synthesized via Gelatin-Modified Silica as Hard Template for Methylene Blue Photodegradation Ulfa, Maria; Rohmah, Istinganah Saetu
Indonesian Journal of Chemistry Vol 26, No 2 (2026)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.107799

Abstract

The escalating occurrence of methylene blue (MB) contamination from textile wastewater underscores the urgent demand for effective photocatalytic remediation. This study presents a depth analysis of Fe2O3-incorporated cobalt photocatalysts synthesized using a gelatin-modified silica hard-template method, followed by calcination at 300 and 550 °C. Structural characterization via XRD, FTIR, and EDX confirmed enhanced crystallinity and Co–O phase formation at elevated temperatures, while BET analysis revealed a reduction in surface area (123.4 to 104.5 m2/g) and pore volume (0.2236 to 0.1875 cm3/g) due to sintering and template removal. FTIR data indicated the attenuation of hydroxyl and water-related bands, suggesting decreased surface hydration at higher temperatures. Despite the decline in surface metrics, α-Fe2O3–Co–550 exhibited superior photocatalytic efficiency, achieving greater than 90% MB degradation under visible light, attributed to an increased cobalt content (Fe:Co≈2:1), improved phase purity, and an optimized electronic structure. Kinetic modeling revealed pseudo-first-order behavior for both samples, with α-Fe2O3-Co-300 showing a higher rate constant (K1 = 0.01116 min−1) yet lower overall degradation performance than α-Fe2O3-Co-550, highlighting the critical interplay of structural order, charge transfer efficiency, and compositional tuning enabled by hard-template synthesis for effective photocatalytic wastewater treatment.
Efficient and Reusable Activated Carbon from Aframomum angustifolium Fruits’ Shells for Removal of Ceftriaxone from Aqueous Solution: Adsorption Isotherms, Kinetics, and Thermodynamics Studies Kasazi, Baraka Alfaksad; Mwakalesi, Alinanuswe Joel; Lema, Emmy Solomon
Indonesian Journal of Chemistry Vol 26, No 2 (2026)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.108042

Abstract

The accumulation of ceftriaxone antibiotics in aquatic systems is a growing global concern due to their potential risks to human and ecological health. The current study investigates the synthesis, characterization, and application of activated carbon (AC-FPAA-H3PO4) made from the shells of Aframomum angustifolium fruits. AC-FPAA-H3PO4 was synthesized using chemical activation (H3PO4, 4 M) followed by pyrolysis at 600 °C for 1 h and characterized using BET, FTIR, and SEM-EDX. AC-FPAA-H3PO4 exhibited a surface area of 1895.6 m2/g, which allowed for its reuse in 5 consecutive cycles without requiring active site regeneration. The optimal removal efficiency (97.8%) was achieved at pH 2, 298.15 K, 100 rpm, 20 g/L adsorbent dosage, and 200 mg/L ceftriaxone concentration. The adsorption process was described by Langmuir (R2 = 0.9862) and Freundlich (R2 = 0.9833) isotherms, and the kinetics were fitted to the pseudo-second-order model. The adsorption was spontaneous (ΔG = −6.80 kJ/mol) and exothermic (ΔH = −4.43 kJ/mol), with increased randomness at the solid-solution interface (ΔS = 7.69 J/mol K). The adsorbent demonstrated high efficiency in removing ceftriaxone from real water samples, including river water (99.36%) and well water (96.92%). The findings suggest AC-FPAA-H3PO4 is a promising adsorbent for removing ceftriaxone from an aqueous environment.
Photocatalytic Degradation of Polyethylene Microplastics Using Microwave-Activated Gadolinium Oxide Catalyst Ismail, Mohammad Luqman; Hanafi, Muhammad Farhan; Zamanhuri, Norezatul Shahirah Ahmad; Sapawe, Norzahir; Nizar, Umar Kalmar; Hamid, Hairul Amani Abdul; Sidik, Siti Munirah; Ibrahim, Siti Fatimah; Danish, Mohammed
Indonesian Journal of Chemistry Vol 26, No 2 (2026)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.108052

Abstract

The persistent presence of polyethylene (PE) microplastics in aquatic environments poses serious environmental and health risks due to their resistance to conventional degradation methods. This study explores the photocatalytic degradation of PE microplastics using microwave-activated gadolinium oxide (Gd2O3) under visible light irradiation. Key operational parameters, including pH solution, catalyst dosage, and initial PE concentration were systematically investigated. Optimal degradation efficiency (68%) was achieved at pH 7, a catalyst dosage of 3 g/L, and a PE concentration of 10 mg/L. Kinetic analysis indicated that the degradation followed a pseudo-first-order model, with a maximum apparent rate constant (Kapp) of 0.0103 min−1 (R2 = 0.9782). The degradation mechanism was further elucidated using the Langmuir–Hinshelwood kinetic model, suggesting a surface-mediated reaction with a high adsorption equilibrium constant (KLH) of 0.4896 L/mg, indicating strong PE adsorption. The reduced degradation efficiency at higher PE concentrations was attributed to the limited generation of reactive oxygen species and increased light scattering. Overall, the findings demonstrate Gd2O3's potential as an efficient, environmentally benign photocatalyst, contributing significantly to the development of rare-earth-based materials for sustainable microplastic remediation in water treatment technologies.
Synthesis, Characterization, and Application of Magnetic Mesoporous MCM-41-Fe3O4 Core-Shell Nanoparticles in the Removal of Eosin Yellow Dye Alattar, Rawaa Abd; Mihsen, Hayder Hamied; Ahmed, Luma Majeed
Indonesian Journal of Chemistry Vol 26, No 2 (2026)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.108056

Abstract

Spinel ferrite (Fe3O4) nanoparticles have been produced as a black powder using precipitation and ultrasonic methods. The framework of MCM-41 was built using sodium silicate as the source of silica and CTAB as a template. Fe3O4 was immobilized on MCM-41 using the microwave method at 100 °C for 20 min, yielding MCM-41-Fe3O4 as a brown solid powder. This characterization was performed using FTIR, XRD, BET, TGA, FESEM-EDX, VSM, AFM, and TEM. The FTIR analysis demonstrated that the MCM-41-Fe3O4 had been properly synthesized. Two M−O bond peaks were discovered, one for the (Fe3+−O2−) octahedral site and one for the (Fe2+−O2−) tetrahedral sites. The XRD analyses revealed that MCM-41-Fe3O4 was synthesized with a highly ordered hexagonal building. The particles exhibited a spherical agglomeration and appeared smooth, as observed in TEM and FESEM examinations. The EDX analysis indicates that it was formed purely from Si, Fe, and O, with a weight percentage of 100%. BET analysis indicated that the sample had a relatively high surface area. In terms of a kinetic model, it was determined that a pseudo-second-order model provided the most suitable description. The thermodynamic study revealed that physical adsorption was exothermic and the adsorption process was nonspontaneous.

Page 199 of 201 | Total Record : 2006

 197   198   199   200   201 

Filter by Year

2001 2026


Reset
Filter By Issues
All Issue Vol 26, No 2 (2026) Vol 26, No 1 (2026) Vol 25, No 5 (2025) Vol 25, No 4 (2025) Vol 25, No 3 (2025) Vol 25, No 2 (2025) Vol 25, No 1 (2025) Vol 24, No 6 (2024) Vol 24, No 5 (2024) Vol 24, No 4 (2024) Vol 24, No 3 (2024) Vol 24, No 2 (2024) Vol 24, No 1 (2024) Vol 23, No 6 (2023) Vol 23, No 5 (2023) Vol 23, No 4 (2023) Vol 23, No 3 (2023) Vol 23, No 2 (2023) Vol 23, No 1 (2023) Vol 22, No 6 (2022) Vol 22, No 5 (2022) Vol 22, No 4 (2022) Vol 22, No 3 (2022) Vol 22, No 1 (2022) Vol 22, No 2 (2022) Vol 21, No 6 (2021) Vol 21, No 5 (2021) Vol 21, No 4 (2021) Vol 21, No 3 (2021) Vol 21, No 2 (2021) Vol 21, No 1 (2021) Vol 20, No 6 (2020) Vol 20, No 5 (2020) Vol 20, No 4 (2020) Vol 20, No 3 (2020) Vol 20, No 2 (2020) Vol 20, No 1 (2020) Vol 19, No 4 (2019) Vol 19, No 3 (2019) Vol 19, No 2 (2019) Vol 19, No 1 (2019) Vol 18, No 4 (2018) Vol 18, No 3 (2018) Vol 18, No 2 (2018) Vol 18, No 1 (2018) Vol 17, No 3 (2017) Vol 17, No 2 (2017) Vol 17, No 1 (2017) Vol 16, No 3 (2016) Vol 16, No 2 (2016) Vol 16, No 1 (2016) Vol 15, No 3 (2015) Vol 15, No 2 (2015) Vol 15, No 1 (2015) Vol 14, No 3 (2014) Vol 14, No 2 (2014) Vol 14, No 1 (2014) Vol 13, No 3 (2013) Vol 13, No 2 (2013) Vol 13, No 1 (2013) Vol 12, No 3 (2012) Vol 12, No 2 (2012) Vol 12, No 1 (2012) Vol 11, No 3 (2011) Vol 11, No 2 (2011) Vol 11, No 1 (2011) Vol 10, No 3 (2010) Vol 10, No 2 (2010) Vol 10, No 1 (2010) Vol 9, No 3 (2009) Vol 9, No 2 (2009) Vol 9, No 1 (2009) Vol 8, No 3 (2008) Vol 8, No 2 (2008) Vol 8, No 1 (2008) Vol 7, No 3 (2007) Vol 7, No 2 (2007) Vol 7, No 1 (2007) Vol 6, No 3 (2006) Vol 6, No 2 (2006) Vol 6, No 1 (2006) Vol 5, No 3 (2005) Vol 5, No 2 (2005) Vol 5, No 1 (2005) Vol 4, No 3 (2004) Vol 4, No 2 (2004) Vol 4, No 1 (2004) Vol 3, No 3 (2003) Vol 3, No 2 (2003) Vol 3, No 1 (2003) Vol 2, No 3 (2002) Vol 2, No 2 (2002) Vol 2, No 1 (2002) Vol 1, No 3 (2001) Vol 1, No 2 (2001) Vol 1, No 1 (2001) Article in press ARTICLE IN PRESS More Issue