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INDONESIA
Communications in Science and Technology
Published by Komunitas Ilmuwan dan Profesional Muslim Indonesia
ISSN : 25029258     EISSN : 25029266     DOI : -
Core Subject : Engineering,
Engineering
Communication in Science and Technology [p-ISSN 2502-9258 | e-ISSN 2502-9266] is an international open access journal devoted to various disciplines including social science, natural science, medicine, technology and engineering. CST publishes research articles, reviews and letters in all areas of aforementioned disciplines. The journal aims to provide comprehensive source of information on recent developments in the field. The emphasis will be on publishing quality articles rapidly and making them freely available to researchers worldwide. All articles will be indexed by Google Scholar, DOAJ, PubMed, Google Metric, Ebsco and also to be indexed by Scopus and Thomson Reuters in the near future therefore providing the maximum exposure to the articles. The journal will be important reading for scientists and researchers who wish to keep up with the latest developments in the field.
Arjuna Subject : -
Articles 209 Documents
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Discovery of thymol-fused chalcones as new competitive \(\alpha\)-glucosidase inhibitors: Design, synthesis, biological evaluation, and molecular modeling studies Danova, Ade; Hermawati, Elvira; Chavasiri, Warinthorn; Mujahidin, Didin; Alni, Anita; Roswanda, Robby
Communications in Science and Technology Vol 9 No 2 (2024)
Publisher : Komunitas Ilmuwan dan Profesional Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21924/cst.9.2.2024.1497

Abstract

This study aims to synthesize and evaluate the inhibitory activity of thymol derivatives targeting ?-glucosidase using in vitro and in silico studies. Ten thymol derivatives (2-11) including five new thymol-fused chalcones (7-11) were successfully synthesized. Among them, four compounds (4, 8, 9, 11) showed the best inhibitory activity with IC50 values of 18.45, 13.75, 8.86, and 10.67µM compared with acarbose (IC50 = 832.82 µM), respectively. The kinetic study of three new thymol-fused chalcones (8, 9, 11) exhibited a competitive inhibition. Molecular docking demonstrated the predicted interactions between ligand (8, 9, 11) and ?-glucosidase, which are responsible for inhibiting the enzyme's catalytic abilities. Furthermore, molecular dynamics simulation of the enzyme-ligand 9 complex indicated that this complex was stable in aqueous condition. This research contributes significantly to the understanding of thymol-fused chalcones that may have therapeutic potential and their possible application in the treatment of type 2 diabetes mellitus (T2DM) for further study.
Klanceng Honey (Tetragonula laeviceps): Its effect on fasting blood glucose, lipid and hematological profiles, and pancreatic histopathology of diabetic rats Agussalim; Umami, Nafiatul; Nurliyani; Wan Ismail, Wan Iryani; Masyithoh, Dewi; Ustadi; Agus, Ali
Communications in Science and Technology Vol 9 No 2 (2024)
Publisher : Komunitas Ilmuwan dan Profesional Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21924/cst.9.2.2024.1503

Abstract

This study aims to assess the daily ingestion of Klanceng Honey (KH) on fasting blood glucose (FBG), high-density lipoprotein (HDL), total cholesterol (TC), triglyceride (TG), low-density lipoprotein (LDL), and pancreatic histopathology. Thirty rats were involved and divided into six groups: G1 = untreated normal rats, G2 = untreated diabetic rats (DR), G3 = DR treated with 0.9 mg/kg BW glibenclamide, G4, G5, and G6 = DR treated with 1, 2, and 3 g/kg BW KH, respectively for 28 days. The FBG level of G1 was found lower than that of diabetic rat groups (G2–G6) (p<0.01). The TC level of G1 group on 14th and 28th days was lower than that of G2–G6 groups (p<0.01). The TG levels in all rat groups showed no significant difference at 0–28 days. On 14th day, the LDL level of diabetic groups were higher than the one in G1 group (p<0.01). Meanwhile, on 14th and 28th, the HDL levels of G3–G6 groups, were higher than the one in G1 group (p<0.01). The pancreatic histopathology of all rat groups showed no abnormalities of the Langerhans islets. The daily ingestion of KH prevented FBG, TC, TG, and LDL levels from rising, increased the HDL levels, and protected the pancreatic glands against damage. T. laeviceps honey can potentially be used as a functional food for therapy of DM patients.
Investigation of hexanal removal through adsorption and photocatalysis on ZIF-7 modified with ZnO, TiO\(_2\), and ZnO/TiO\(_2\) using ATR-FTIR Naufal, Widyan Muhammad; Wahyuningsih, Sayekti; Lestari, Witri Wahyu
Communications in Science and Technology Vol 9 No 2 (2024)
Publisher : Komunitas Ilmuwan dan Profesional Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21924/cst.9.2.2024.1505

Abstract

Zeolitic imidazolate framework (ZIF) is renowned for its high adsorption capacity and frequently adsorbs organic pollutants. However, its high band gap energy has limited its photocatalytic activity, thus necessitating a modification for enhance performance enhancement. This study focuses on developing a ZIF-7 composite material that integrates adsorption and photocatalysis to remove volatile organic compounds (VOCs), particularly hexanal. Modifications were made by incorporating ZnO, TiO2, and ZnO/TiO2 via a solvothermal method using dimethylformamide (DMF). ATR-FTIR analysis was employed to monitor any changes in peak intensity related to the C=O vibrations of hexanal around 1700 cm-1. The results showed that all samples effectively adsorbed hexanal, reducing peak intensity after UV irradiation, and confirming successful photocatalysis. Notably, TiO2@ZIF-7 exhibited the highest photocatalytic performance with 88.06% degradation efficiency. This study confirms that the ATR-FTIR method can be used to monitor the success of adsorption and photocatalysis and shows the potential for developing composite materials to remove VOCs such as hexanal.
One pot two-step borylation/fluorination reaction of dysobinin from Chisocheton macrophyllus and its cytotoxicity against cancer cell Huda, Muhammad Badrul; Nurlelasari; Safriansyah, Wahyu; Fajar, Mohamad; Widiyowati, Iis Intan; Supratman, Unang; Permana, Yessi; Budiman, Yudha P.
Communications in Science and Technology Vol 9 No 2 (2024)
Publisher : Komunitas Ilmuwan dan Profesional Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21924/cst.9.2.2024.1514

Abstract

Dysobinin is a naturally occurred limonoid, which is a specific form of triterpenoid, mostly found in certain plants, particularly the Meliaceae family. Overall, it has been found that limonoids have a wide range of biological functions. Typically, the compound comprises anticancer, antimicrobial, and anti-inflammatory properties. Even though dysobinin has shown some effectiveness, its potential in pharmacology, so far, is found limited. This study, therefore, aims to enhance the pharmacological properties of dysobinin through the addition of fluorine. To do this, a one-pot, two-step reaction comprising C-H borylation and selectfluor was used to turn dysobinin into two new compounds: 1,2-dihydro-6?-acetoxyazadirone (5) and 1?-fluorodysobinin (6). After the transformation, various spectroscopic methods, including UV (Ultraviolet), IR (infrared), MS (mass spectra), as well as NMR (1D and 2D) were applied to figure out the structures of the new compounds. Accordingly, of the derived compounds, 1?-fluorodysobinin showed significantly higher cytotoxicity against A549 lung cancer cells when compared to dysobinin.
Conductivity and mechanical properties of PEO/PVA/UiO-66 composite polymers for membrane of lithium-ion batteries Patah, Aep; Rochliadi, Achmad; Husein, Aditya; Ramadhan, Dadang
Communications in Science and Technology Vol 9 No 2 (2024)
Publisher : Komunitas Ilmuwan dan Profesional Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21924/cst.9.2.2024.1515

Abstract

Lithium batteries are crucial for energy storage in electronics, transportation, and industrial sectors. However, lithium-ion battery separators such as Celgard require significant improvements, particularly in ionic conductivity (?). Combining Metal-Organic Frameworks (MOFs) with polymers is expected to create a separator membrane that enhances conductivity and mechanical properties in lithium-ion batteries. UiO-66 MOFs were synthesized using the solvothermal method at 120? and then composited with polyethylene oxide (PEO) and polyvinyl alcohol (PVA) polymer membranes using the solution casting method. The UiO-66 MOFs/PEO/PVA polymer composites were made by varying the UiO-66 content from 2% to 8% (w/w) while keeping a constant LiPF6 concentration of 9% (w/w). These composites were characterized using X-ray Diffraction (XRD) and Fourier-Transform Infrared spectroscopy (FTIR). Subsequently, the EIS test and tensile tests assessed the performance of the composite membranes. The resulting membrane with 6% (w/w) UiO-66 MOFs exhibited a conductivity (?) of 5.60 × 10–3 S cm–1 and a tensile strength of 32.5 MPa.
Enhancing dissolving pulp quality of mixed raw materials through pre-hydrolysis kraft-cooking: A study on Acacia crassicarpa and Terminalia catappa Sahan, Yusnimar; Rahmi, Sri Wahdini; Evelyn; Herman, Syamsu; Chairul; Khairat; Ohi, Hiroshi; Amri, Amun
Communications in Science and Technology Vol 9 No 2 (2024)
Publisher : Komunitas Ilmuwan dan Profesional Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21924/cst.9.2.2024.1519

Abstract

Acacia crassicarpa wood is widely used in Indonesia as a raw material for dissolving pulp (DP) by the kraft-cooking process. Given that Indonesia has a rich variety and abundance of cellulose-rich wood, it is deemed crucial to research alternative raw materials, such as Terminalia catappa wood. As an alternative source of raw material, Terminalia catappa possesses excellent adaptability to various environmental conditions and is easy to grow everywhere. The current research sought to produce DP using the mixtures of materials from these two plant species as raw materials by pre-hydrolysis, kraft-cooking, and Elementary Chlorine Free (ECF) bleaching. The DP produced had ISO brightness > 88%, alpha-cellulose content > 94%, viscosity > 6.2 cP, and pentosan content of 2.54%. The DP quality traits have met the SNI 938:2017 standards for rayon-grade pulp. Acacia Crassicarpa and Terminalia Catappa are the prospective wood mixture for producing high-quality dissolving pulp via the kraft-cooking process.
Investigating the antimicrobial activity of silver nanoparticles with varying charges green-synthesized from Tabebuia rosea flower Nguyen, Trung Dien; Nguyen, Thao Phuc-Nguyen; Thai, Nhung Thi-Tuyet; Hoang, Yen Hai; Trinh, Gia Thi-Ngoc
Communications in Science and Technology Vol 9 No 2 (2024)
Publisher : Komunitas Ilmuwan dan Profesional Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21924/cst.9.2.2024.1521

Abstract

The integration of nanotechnology and biomedicine has driven a significant interest in silver nanoparticles due to their unique properties. This study presents a novel approach by combining Tabebuia rosea flower extract and chitosan to manipulate the surface charges of synthesized silver nanoparticles. These biosynthesized nanoparticles, presenting negative, neutral, and positive charges, were thoroughly analyzed by means of a number of techniques including Ultraviolet-visible spectroscopy, X-ray diffraction, transmission electron microscopy, and Fourier-transform infrared spectroscopy. By incorporating chitosan, the zeta potential of the green-synthesized nanomaterials was modified, shifting from negative to positive. The resultant silver nanoparticles showed the zeta potentials of –24.8 mV for negatively charged particles, +22.9 mV for positively charged ones, and neutrality at approximately 0.04% chitosan. Meanwhile, the particle sizes for the negative, neutral, and positive nanomaterials were 19.7, 15.8, and 14.2 nm, respectively. The antimicrobial and anticancer activities of these biosynthesized nanoparticles were evaluated against gram-negative bacteria (Pseudomonas aeruginosa, Escherichia coli, and Salmonella enterica), gram-positive bacteria (Bacillus subtilis, Lactobacillus fermentum, and Staphylococcus aureus), and cancer cell lines (A549, Hep-G2, KB, and MCF-7). These results highlight the crucial role of surface stabilizers, particle size, and charge in determining the biomedical potential of nanosilver particles. Notably, the biosynthesized silver nanoparticles exhibited a number of promising antimicrobial and anticancer properties, emphasizing their potential for biomedical applications.
Nitrogen fertilizer use reduction by two endophytic diazotrophic bacteria for soil nutrients and corn yield Chuong, Nguyen Van; Nguyen Ngoc Phuong, Trang; Nguyen Van, Thuan
Communications in Science and Technology Vol 9 No 2 (2024)
Publisher : Komunitas Ilmuwan dan Profesional Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21924/cst.9.2.2024.1527

Abstract

Today, the utilization of endophytic diazotrophic bacteria (EDB) purposely to minimize the application of urea fertilizer (UF), and enhance soil fertility, crop quality and corn yield in sustainable agricultural practices is an inevitable trend. The experiment was arranged outside the AGU green house of Agriculture Research Center, An Giang university, Vietnam, which consisted of two factors: (i) two EDB species [Bacillus sp. NTLG2-20 (Bacillus A) and Bacillus arybhattai strain CM44 (Bacillus B)] and (ii) three UF ratios (0.0, 100 and 200 kg N ha-1) and four replications. Research data presented that the fresh cob yield of Bacillus A was found 4.0% higher than that of Bacillus B and 12.7% than that of non EDB inoculation. Furthermore, the inoculation of Bacillus B had 9.02% higher fresh cob yield compared to non-inoculation. The 50% reduction of UF application combined EDB addition obtained the fresh cob with no significant difference, compared to 100% recommended urea application. The interaction between the effectiveness of EDB inoculation and UF reduction was clearly different in favor of corn grown on sandy loam soils with low nutrient contents. Both Bacillus A and Bacillus B had the abilities of high yield and good nitrogen fixation with the potential to simultaneously improve soil fertility and corn yield. The results of this study demonstrated that two strains of Bacillus A and Bacillus B have the potential to promote the growth and increase the yield of peanuts, and it should be suggested for future biological fertilizer production.
Novel colored biomass-waste from food industry sector derived hierarchical porous carbon nanofiber for robust symmetric supercapacitor Nursyaputri, Wan Mery; Fairuzy, Zeeva Khalilah; Khumairah, Zahra; Yanti, Novi; Nursyafni, Nursyafni; Apriwandi, Apriwandi; Taslim, Rika; Taer, Erman
Communications in Science and Technology Vol 9 No 2 (2024)
Publisher : Komunitas Ilmuwan dan Profesional Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21924/cst.9.2.2024.1534

Abstract

A major challenge in the use of supercapacitor energy storage applications is optimizing 3D-hierarchical porous and 2D nanofiber structures to improve the electrochemical performance of colored biomass-derived activated carbon (AC). Therefore, this study aims to synthesize AC from Dracaena Angustifolia (DA) leaves and dregs using a sustainable method through chemical activation and high-temperature pyrolysis. AC was designed to be adhesive-free to maintain the true mechanical properties of the precursor. Research results showed that the sample of DA-dregs-KOH shows optimal results with a specific surface area (317.66 m2 g-1). The electrochemical performance of hierarchical porous carbon treated with 1 M H2SO4 electrolyte in a 2-electrode system had a nanofiber structure with the highest specific capacitance (248 F g-1) at 1 A g-1 and energy density (12.96 Wh kg-1) with a coulomb efficiency 84.1%. Based on these results, DA dreg-KOH based porous AC with hierarchical porous morphology shows significant potential to be used as binder-free electrode materials that can produce high-performance supercapacitors as a new renewable and sustainable energy storage solution.
Fixing cobalt metal onto mordenite through spray impregnation and its evaluation as a catalyst in transforming used coconut cooking oil into bio-jet fuel Saviola, Aldino Javier; Wijaya, Karna; Syoufian, Akhmad; Vebryana, Marini Fairuz; Anggraeni, Widuri; Rozana, Kharistya; Darsono, Nono; Saputra, Dita Adi; Saputri, Wahyu Dita
Communications in Science and Technology Vol 9 No 2 (2024)
Publisher : Komunitas Ilmuwan dan Profesional Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21924/cst.9.2.2024.1535

Abstract

Given the challenges posed by fossil-based jet fuel, research into bio-jet fuel production has intensified to achieve carbon neutrality. The present work reports a significant breakthrough with the successful conversion of used coconut cooking oil into bio-jet fuel utilizing a cobalt-impregnated mordenite catalyst. Cobalt was introduced to mordenite via the spray impregnation method at a concentration of 2% using a CoCl?·6H?O solution. The resultant catalyst was characterized using FTIR, XRD, NH?-TPD, SAA, FESEM-EDX Mapping, TEM, XPS, and TG/DTA instruments. Hydrotreatment was conducted in a semi-batch reactor at atmospheric pressure, employing H? gas at a flow rate of 20 mL/min and a catalyst-to-feed ratio of 1:200 (w/w) for a duration of 2 h. The addition of cobalt significantly enhanced the efficiency of the hydrotreatment by improving the catalytic performance of mordenite as a support material. The liquid product conversion and total bio-jet fuel yield obtained from the hydrotreatment of used coconut cooking oil using the Co/mordenite catalyst were 60.25% and 51.11%, respectively. The highest selectivity for bio-jet fuel was observed in fraction II (450–550 °C) at 88.90%. This catalyst exhibited sustained performance over three consecutive runs, indicating its potential application in the future biofuel industry. Altogether, this research reveals the possibility of employing used coconut cooking oil as a sustainable and promising feedstock to be converted into bio-jet fuel by hydrodeoxygenation and/or hydrocracking reactions.

Page 18 of 21 | Total Record : 209

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